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https://www.readbyqxmd.com/read/29141236/concentrations-of-a-pgf2%C3%AE-metabolite-during-pregnancy-on-the-days-that-luteolysis-occurs-in-nonbred-heifers
#1
REVIEW
F L V Pinaffi, E R Araujo, O J Ginther
Concentrations of a metabolite of PGF2α (PGFM) were compared between nonbred (n = 6) and pregnant (n = 8) heifers on days 16, 17, and 18 postovulation. On each day, an 8-h session of hourly blood sampling was done. Averaged over the 8-h sessions, mean concentration of PGFM was less (P < 0.0009) in the pregnant group (45.2 ± 3.2 pg/mL) than that in the nonbred group (65.6 ± 7.9 pg/mL), but the minimal concentration per session was not significantly different between groups. Pulses of PGFM (identified by coefficient of variance) were similar in frequency between groups but were less (P < 0...
November 3, 2017: Domestic Animal Endocrinology
https://www.readbyqxmd.com/read/29141040/medical-therapy-versus-radiofrequency-endometrial-ablation-in-the-initial-treatment-of-heavy-menstrual-bleeding-itom-trial-a-clinical-and-economic-analysis
#2
Abimbola O Famuyide, Shannon K Laughlin-Tommaso, Sherif A Shazly, Kirsten Hall Long, Daniel M Breitkopf, Amy L Weaver, Michaela E McGree, Sherif A El-Nashar, Maureen A Lemens, Matthew R Hopkins
BACKGROUND: Radiofrequency endometrial ablation (REA) is currently a second line treatment in women with heavy menstrual bleeding (MHB) if medical therapy (MTP) is contraindicated or unsatisfactory. Our objective is to compare the effectiveness and cost burden of MTP and REA in the initial treatment of HMB. METHODS: We performed a randomized trial at Mayo Clinic Rochester, Minnesota. The planned sample size was 60 patients per arm. A total of 67 women with HMB were randomly allocated to receive oral contraceptive pills (Nordette ®) or Naproxen (Naprosyn®) (n = 33) or REA (n = 34)...
2017: PloS One
https://www.readbyqxmd.com/read/29138942/calculation-of-left-ventricular-volumes-and-ejection-fraction-from-dynamic-cardiac-gated-15-o-water-pet-ct-5d-pet
#3
Jonny Nordström, Tanja Kero, Hendrik Johannes Harms, Charles Widström, Frank A Flachskampf, Jens Sörensen, Mark Lubberink
BACKGROUND: Quantitative measurement of myocardial blood flow (MBF) is of increasing interest in the clinical assessment of patients with suspected coronary artery disease (CAD). (15)O-water positron emission tomography (PET) is considered the gold standard for non-invasive MBF measurements. However, calculation of left ventricular (LV) volumes and ejection fraction (EF) is not possible from standard (15)O-water uptake images. The purpose of the present work was to investigate the possibility of calculating LV volumes and LVEF from cardiac-gated parametric blood volume (V B) (15)O-water images and from first pass (FP) images...
November 14, 2017: EJNMMI Physics
https://www.readbyqxmd.com/read/29138552/sirt1-and-foxo1-mrna-expression-in-pbmc-correlates-to-physical-activity-in-copd-patients
#4
Chihiro Taka, Ryuji Hayashi, Kazuki Shimokawa, Kotaro Tokui, Seisuke Okazawa, Kenta Kambara, Minehiko Inomata, Toru Yamada, Shoko Matsui, Kazuyuki Tobe
Background: Physical activity (PA) is considered as one of the most important prognostic predictors in chronic obstructive pulmonary disease (COPD) patients. Longevity gene, SIRT1, is reported to be involved in the pathogenesis of COPD by regulating the signaling pathways of oxidative stress, inflammation, and aging. We hypothesize that SIRT1 and related genes are also associated with the benefits of PA in COPD patients. Methods: Eighteen COPD outpatients were enrolled in this study, and their PA level was assessed with an accelerometer...
2017: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/29138449/haemodynamic-recovery-properties-of-the-torsioned-testicular-artery-lumen
#5
Selda Goktas, Ozlem Yalcin, Erhan Ermek, Senol Piskin, Can T Capraz, Yusuf O Cakmak, Kerem Pekkan
Testicular artery torsion (twisting) is one such severe vascular condition that leads spermatic cord injury. In this study, we investigate the recovery response of a torsioned ram testicular artery in an isolated organ-culture flow loop with clinically relevant twisting modes (90°, 180°, 270° and 360° angles). Quantitative optical coherence tomography technique was employed to track changes in the lumen diameter, wall thickness and the three-dimensional shape of the vessel in the physiological pressure range (10-50 mmHg)...
November 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29137909/use-of-expired-air-carbon-monoxide-testing-in-clinical-tobacco-treatment-settings
#6
REVIEW
Adam O Goldstein, Stephanie P Gans, Carol Ripley-Moffitt, Chris Kotsen, Matthew Bars
Carbon Monoxide (CO) testing is considered an easy, non-invasive, and objective contribution to the assessment of smoking behavior, as CO is rapidly absorbed into the blood stream when lit cigarettes or cigars are inhaled. CO testing is a medically important, billable outpatient service that can contribute to sustainability of face-to-face tobacco use treatment services by clinicians. This article reviews research on the clinical use of CO testing to provide bio-medical feedback in assessing smoking behavior, on educating smokers on tobacco health effects, on assisting with treatment planning, and as a motivational tool to encourage people to become tobacco free...
November 11, 2017: Chest
https://www.readbyqxmd.com/read/29137853/antidiabetic-antihyperlipidemic-activities-and-herb-drug-interaction-of-a-polyherbal-formulation-in-streptozotocin
#7
Vishnu P Choudhari, Ketkee P Gore, Anil T Pawar
BACKGROUND: Ojamin (OJ), a polyherbal antidiabetic formulation, is extensively used as a food supplement to control diabetes alone or along with synthetic antidiabetic agents. However, it's phytochemical and pharmacological investigations are lacking. OBJECTIVE: The present study was undertaken to study antidiabetic and antihyperlipidemic potentials of OJ and its interaction with Metformin in streptozotocin (STZ)-induced diabetic rats. MATERIALS AND METHODS: Diabetes was induced in Wistar rats by single intraperitoneal (i...
November 11, 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/29137496/preoperative-quantitative-dynamic-contrast-enhanced-mri-and-diffusion-weighted-imaging-predict-aggressive-disease-in-endometrial-cancer
#8
Kristine E Fasmer, Atle Bjørnerud, Sigmund Ytre-Hauge, Renate Grüner, Ingvild L Tangen, Henrica Mj Werner, Line Bjørge, Øyvind O Salvesen, Jone Trovik, Camilla Krakstad, Ingfrid S Haldorsen
Background Quantitative dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) and diffusion-weighted imaging (DWI) may yield preoperative tumor biomarkers relevant for prognosis and therapy in cancer. Purpose To explore the value of preoperative DCE-MRI and DWI for the prediction of aggressive disease in endometrial cancer patients. Material and Methods Preoperative MRI (1.5-T) from 177 patients were analyzed and imaging parameters reflecting tumor microvasculature (from DCE-MRI) and tumor microstructure (from DWI) were estimated...
January 1, 2017: Acta Radiologica
https://www.readbyqxmd.com/read/29137200/a-lab-on-a-chip-based-non-invasive-optical-sensor-for-measuring-glucose-in-saliva
#9
Dong Geon Jung, Daewoong Jung, Seong Ho Kong
A lab-on-a-chip (LOC)-based non-invasive optical sensor for measuring glucose in saliva was fabricated. Existing glucose sensors utilizing blood require acquisition of a blood sample by pricking the finger, which is painful and inconvenient. To overcome these limitations, we propose a non-invasive glucose sensor with LOC, micro-electro-mechanical system and optical measurement technology. The proposed sensor for measuring glucose in saliva involves pretreatment, mixing, and measurement on a single tiny chip...
November 13, 2017: Sensors
https://www.readbyqxmd.com/read/29136193/early-first-trimester-uteroplacental-flow-and-the-progressive-disintegration-of-spiral-artery-plugs-new-insights-from-contrast-enhanced-ultrasound-and-tissue-histopathology
#10
V H J Roberts, T K Morgan, P Bednarek, M Morita, G J Burton, J O Lo, A E Frias
STUDY QUESTION: Does the use of a vascular contrast agent facilitate earlier detection of maternal flow to the placental intervillous space (IVS) in the first trimester of pregnancy? SUMMARY ANSWER: Microvascular filling of the IVS was demonstrated by contrast-enhanced ultrasound from 6 weeks of gestation onwards, earlier than previously believed. WHAT IS KNOWN ALREADY: During placental establishment and remodeling of maternal spiral arteries, endovascular trophoblast cells invade and accumulate in the lumen of these vessels to form 'trophoblast plugs'...
November 10, 2017: Human Reproduction
https://www.readbyqxmd.com/read/29136041/profiling-analysis-of-circulating-microrna-in-peripheral-blood-of-patients-with-class-iv-lupus-nephritis
#11
Elkin Navarro-Quiroz, Lisandro Pacheco-Lugo, Roberto Navarro-Quiroz, Hernan Lorenzi, Pierine España-Puccini, Yirys Díaz-Olmos, Lisneth Almendrales, Valeria Olave, Henry Gonzalez-Torres, Anderson Diaz-Perez, Alex Dominguez, Antonio Iglesias, Raul García, Gustavo Aroca-Martinez
Renal involvement in Systemic Lupus Erythematous (SLE) patients is one of the leading causes of morbidity and a significant contributor to mortality. It's estimated that nearly 50% of SLE individuals develop kidney disease in the first year of the diagnosis. Class IV lupus nephritis (LN-IV) is the class of lupus nephritis most common in Colombian patients with SLE. Altered miRNAs expression levels have been reported in human autoimmune diseases including lupus. Variations in the expression pattern of peripheral blood circulating miRNAs specific for this class of lupus nephritis could be correlated with the pathophysiological status of this group of individuals...
2017: PloS One
https://www.readbyqxmd.com/read/29135155/-laser-therapy-for-male-infertility-part-1-etiology-and-pathogenesis-experimental-studies
#12
O I Apolikhin, S V Moskvin
Male infertility is associated with a wide range of pathological conditions affecting both the sexual and other body systems: endocrine, nervous, blood, and immune. Laser therapy is a form of modern physiotherapy that applies low-intensity laser radiation in various parts of the body. It is widely used in all areas of modern medicine due to its high efficiency, ease of use, the absence of contraindications and side effects. The authors reviewed the results of 171 studies investigating laser therapy, of which 93 were experimental (20 in Russian and 73 international publications), 4 clinical and experimental (all in Russian), 74 clinical (73 in Russian and 1in English)...
October 2017: Urologii︠a︡
https://www.readbyqxmd.com/read/29134982/electrocardiographic-and-blood-pressure-measurements-in-captive-african-lions-panthera-leo-immobilized-with-xylazine-ketamine-combination
#13
T O Omóbòwálé, P I Otuh, O A Adejumobi, J O Abiola, T Adebiyi, B N Ogunro, A O Adeogun
Electrocardiographic and blood pressure measurements are extremely valuable diagnostic tools in the evaluationof the cardiovascular system of living animals. In this study, 6-lead electrocardiograms were recorded from five male captiveAfrican lions (Panthera leo). Also, blood pressure measurements were recorded and compared from three different sites;fore limb, hind limb and the tail, were recorded. Immobilization was done with a combination of Ketamine Hydrochloride(10mg/kg) and Xylazine (3mg/kg). Measurements were recorded as mean ± standard deviation...
June 30, 2017: Nigerian Journal of Physiological Sciences: Official Publication of the Physiological Society of Nigeria
https://www.readbyqxmd.com/read/29134980/association-between-adiponectin-serum-lipids-and-obesity-in-a-university-setting-in-nigeria
#14
F L Ciroma, J O Ayo, A Mohammed, M B Akor-Dewu, M A Kana, S N Kase
Obesity is an energy imbalance condition, which is accompanied by metabolic and cardiovascular complications.Adiponectin, produced by adipocytes, is an important adipokine involved in carbohydrate and lipid metabolism. Adiponectinlevel is altered in obesity in various populations. In Nigeria, very few studies regarding adiponectin exist, and none, to thebest of our knowledge, investigated the relationship between adiponectin and lipid profile and obesity. Therefore, this studyaims to evaluate changes in adiponectin level and serum lipids with body mass index, and investigate the relationship betweenadiponectin, serum lipids and obesity in Nigerian adults...
June 30, 2017: Nigerian Journal of Physiological Sciences: Official Publication of the Physiological Society of Nigeria
https://www.readbyqxmd.com/read/29134979/amlodipine-corrects-changes-in-blood-pressure-and-baroreceptor-reflex-sensitivity-in-sprague-dawley-rats-fed-a-high-salt-diet
#15
A A Adejare, O A Sofola
High dietary salt ingestion causes elevated blood pressure both in humans and in experimental animals.Following reports that Calcium Channel Blockers may exhibit differences in the response of blood vessels to pressor agents,this study sought to test the effects of amlodipine on blood pressure (BP) and baroreceptor reflex sensitivity (BRS) responsesto high salt ingestion. Three groups of weanling Sprague-Dawley rats i.e. control rats (CR), salt loaded rats (SR) and saltloaded rats concomitantly administered orally with amlodipine (SR+Am) were used...
June 30, 2017: Nigerian Journal of Physiological Sciences: Official Publication of the Physiological Society of Nigeria
https://www.readbyqxmd.com/read/29134977/metformin-effects-are-augmented-by-chronic-intermittent-cold-stress-in-high-fat-diet-fed-male-wistar-rats
#16
A O Ige, O I Iwaloye, E O Adewoye
This study investigated the effects of metformin on some glucose regulatory indices in high fat diet (HFD) fedmale Wistar rats exposed to room temperature and chronic intermittent cold stress (CICS). Thirty rats were randomly dividedinto 5 groups. Group 1(control) was maintained on standard rat chow while groups 2-5 were maintained on HFD for 8weeksrespectively prior to experimental procedures. Control, group 2(HFD untreated) and group 3(HFD+metformin (250mg/kg)were exposed to room temperature while groups 4(HFD untreated+CICS) and 5(HFD+CICS+metformin) were exposed toCICS for 21days...
June 30, 2017: Nigerian Journal of Physiological Sciences: Official Publication of the Physiological Society of Nigeria
https://www.readbyqxmd.com/read/29134974/differences-in-physical-physiological-and-motor-performance-traits-between-volleyball-and-basketball-athletes-in-a-university-in-ghana
#17
A Obour, M O Moses, B Baffour-Awuah, B Asamoah, P K Sarpong, F Osei, L G Akwa, E J Appiah
Physical, physiological and motor performance traits play substantial role in both volleyball (VB) and basketball(BB) competitions. The differences in these traits among University athletes in Ghana have not been reported. Hence, thisstudy documents and compares the physical, physiological and motor performance traits of VB and BB university athletes.Purposive sampling technique involving thirty-five university athletes (24 males and 11 females) with mean age of 21.77 ±2.03years was used. Height, weightn, waist and hip circumferences, waist to hip ratio (WHR), body mass index (BMI), heartrate (HR), systolic blood pressure (SBP) and diastolic blood pressure (DBP), shoulder muscular endurance (SME), abdominal muscular endurance (AME), left and right Arm Strength, Leg Power, Reaction time, Agility and Speed traits were measured...
June 30, 2017: Nigerian Journal of Physiological Sciences: Official Publication of the Physiological Society of Nigeria
https://www.readbyqxmd.com/read/29134973/effect-of-cortisol-on-plasma-lactate-levels-following-cortisolinduced-hyperglycaemia-in-common-african-toad-bufo-regularis
#18
G O Isehunwa, O T Oladun, J E Akpan, A R A Alada
Previous studies in man have shown that cortisol induces hyperglycemia through gluconeogenesis. However,the metabolic substrates involved in cortisol-induced hyperglycemia and the role of adrenergic receptors in lactate productionin toads have not been well studied. This study investigated the effects of adrenergic receptor blockers in cortisol-inducedhyperglycemia and blood lactate levels in the common African toad (Bufo regularis). Each toad was fasted and anaesthetizedwith sodium thiopentone given intraperitoneally (50mg/kg/i...
June 30, 2017: Nigerian Journal of Physiological Sciences: Official Publication of the Physiological Society of Nigeria
https://www.readbyqxmd.com/read/29132841/pelargonidin-3-o-glucoside-and-its-metabolites-have-modest-anti-inflammatory-effects-in-human-whole-blood-cultures
#19
Anna M Amini, Karolin Muzs, Jeremy Pe Spencer, Parveen Yaqoob
This study hypothesized that the predominant strawberry anthocyanin, pelargonidin-3-O-glucoside (Pg-3-glc), and 3 of its plasma metabolites (4-hydroxybenzoic acid, protocatechuic acid, and phloroglucinaldehyde [PGA]) would affect phagocytosis, oxidative burst, and the production of selected pro- and anti-inflammatory cytokines in a whole blood culture model. For the assessment of phagocytosis and oxidative burst activity of monocytes and neutrophils, whole blood was preincubated in the presence or absence of the test compounds at concentrations up to 5 μmol/L, followed by analysis of phagocytic and oxidative burst activity using commercially available test kits...
September 21, 2017: Nutrition Research
https://www.readbyqxmd.com/read/29132768/pr%C3%A3-vention-et-prise-en-charge-de-l%C3%A2-infection-herp%C3%A3-tique-au-cours-de-la-grossesse-et-de-l%C3%A2-accouchement%C3%A2-recommandations-pour-la-pratique-clinique-%C3%A2-%C3%A2-texte-des-recommandations-texte-court
#20
M-V Sénat, O Anselem, O Picone, L Renesme, N Sananès, C Vauloup-Fellous, Y Sellier, J-P Laplace, L Sentilhes
OBJECTIVE: Identify measures to diagnose, prevent and treat genital herpes infection during pregnancy and childbirth and neonatal infection. METHODS: Bibliographic search from Medline, Cochrane Library databases and research of international clinical practice guidelines. RESULTS: Genital herpes lesion is most often due to HSV2 (LE2). The risk of HSV seroconversion during pregnancy is 1 to 5% (LE2). Genital herpes ulceration during pregnancy in a woman with history of genital herpes corresponds with a recurrence...
November 10, 2017: Gynecologie, Obstetrique, Fertilite & Senologie
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