keyword
MENU ▼
Read by QxMD icon Read
search

poly trauma

keyword
https://www.readbyqxmd.com/read/29429577/epidemiology-of-distal-radius-fractures-in-polytrauma-patients-and-the-influence-of-high-traumatic-energy-transfer
#1
Steven Ferree, Quirine M J van der Vliet, Femke Nawijn, Abhiram R Bhashyam, Roderick M Houwert, Luke P H Leenen, Falco Hietbrink
INTRODUCTION: For several extremity fractures differences in morphology, incidence rate and functional outcome were found when polytrauma patients were compared to patients with an isolated injury. This is not proven for distal radius fractures (DRF). Therefore, this study aimed to analyse fracture morphology in relation to energy transfer in both poly- and mono-trauma patients with a DRF. METHODS: This was a retrospective cohort study. All patients aged 16 years and older with a DRF were included...
February 5, 2018: Injury
https://www.readbyqxmd.com/read/29415850/patterns-of-co-occurring-addictions-posttraumatic-stress-disorder-and-major-depressive-disorder-in-detoxification-treatment-seekers-implications-for-improving-detoxification-treatment-outcomes
#2
RaeAnn E Anderson, Bryce Hruska, Alec P Boros, Christopher J Richardson, Douglas L Delahanty
BACKGROUND AND OBJECTIVES: Poly-substance use and psychiatric comorbidity are common among individuals receiving substance detoxification services. Posttraumatic stress disorder (PTSD) and major depressive disorder (MDD) are the most common co-occurring psychiatric disorders with substance use disorder (SUD). Current treatment favors a one-size-fits-all approach to treating addiction focusing on one substance or one comorbidity. Research examining patterns of substance use and comorbidities can inform efforts to effectively identify and differentially treat individuals with co-occurring conditions...
March 2018: Journal of Substance Abuse Treatment
https://www.readbyqxmd.com/read/29411694/why-polyvictimization-matters
#3
David A Wolfe
The five important papers in this series reflect the evolving state of research on violence and victimization. Their findings and methods underscore the importance of studying poly-victimization as the more encompassing genesis of harm across stages of development, rather than singular, isolated events. That is, children and youth who experience one type of violence are more likely than not to have experienced (or will experience) many others. Poly-victimized children become victims of further abuse and trauma and, in turn, are at increased risk of becoming perpetrators toward peers and future partners...
March 2018: Journal of Interpersonal Violence
https://www.readbyqxmd.com/read/29398989/the-primary-stability-of-a-bioabsorbable-poly-l-lactic-acid-suture-anchor-for-rotator-cuff-repair-is-not-improved-with-polymethylmethacrylate-or-bioabsorbable-bone-cement-augmentation
#4
Mehmet F Güleçyüz, Michael Kraus-Petersen, Christian Schröder, Andreas Ficklscherer, Markus U Wagenhäuser, Christian Braun, Peter E Müller, Matthias F Pietschmann
Background: The incidence of osteoporosis and rotator cuff tears increases with age. Cement augmentation of bones is an established method in orthopedic and trauma surgery. Questions/Purposes: This study analyses if polymethylmethacrylate or bioabsorbable cement can improve the primary stability of a bioabsorbable suture anchor in vitro in comparison to a non-augmented suture anchor in osteoporotic human humeri. Methods: The trabecular bone mineral density was measured to ensure osteopenic human specimens...
February 2018: HSS Journal: the Musculoskeletal Journal of Hospital for Special Surgery
https://www.readbyqxmd.com/read/29398669/anti-inflammatory-effect-of-tranexamic-acid-against-trauma-hemorrhagic-shock-induced-acute-lung-injury-in-rats
#5
Yue Teng, Cong Feng, Yunen Liu, Hongxu Jin, Yan Gao, Tanshi Li
It has been demonstrated that tranexamic acid (TXA), a synthetic derivative of lysine, alleviates lung damage in a trauma-hemorrhagic shock (T/HS) model. Nevertheless, the mechanism of TXA against acute lung injury (ALI) has not deeply elaborated. In this study, we generated a T/HS rat model based on previous research, and TXA (50 mg/kg and 100 mg/kg) was intravenously injected into these rats prior to or post T/HS. The results revealed that the decreased survival rate and impaired lung permeability of the rats caused by T/HS were improved by TXA pretreatment or posttreatment...
February 2, 2018: Experimental Animals
https://www.readbyqxmd.com/read/29364821/effects-of-protein-coated-nanofibers-on-conformation-of-gingival-fibroblast-spheroids-potential-utility-for-connective-tissue-regeneration
#6
Gili Kaufman, Ryan A Whitescarver, Laiz Nunes, Xavier-Lewis Palmer, Drago Skrtic, Wojtek Tutak
Deep wounds in the gingiva caused by trauma or surgery require a rapid and robust healing of connective tissues. We propose utilizing gas-brushed nanofibers coated with collagen and fibrin for that purpose. Our hypotheses are that protein-coated nanofibers will: (i) attract and mobilize cells in various spatial orientations, and (ii) regulate the expression levels of specific extracellular matrix (ECM)-associated proteins, determining the initial conformational nature of dense and soft connective tissues. Gingival fibroblast monolayers and 3D spheroids were cultured on ECM substrate and covered with gas-blown poly-(DL-lactide-co-glycolide) (PLGA) nanofibers (uncoated/coated with collagen and fibrin)...
January 24, 2018: Biomedical Materials
https://www.readbyqxmd.com/read/29352556/what-causes-psychosis-an-umbrella-review-of-risk-and-protective-factors
#7
Joaquim Radua, Valentina Ramella-Cravaro, John P A Ioannidis, Abraham Reichenberg, Nacharin Phiphopthatsanee, Taha Amir, Hyi Yenn Thoo, Dominic Oliver, Cathy Davies, Craig Morgan, Philip McGuire, Robin M Murray, Paolo Fusar-Poli
Psychosis is a heterogeneous psychiatric condition for which a multitude of risk and protective factors have been suggested. This umbrella review aimed to classify the strength of evidence for the associations between each factor and psychotic disorders whilst controlling for several biases. The Web of Knowledge database was searched to identify systematic reviews and meta-analyses of observational studies which examined associations between socio-demographic, parental, perinatal, later factors or antecedents and psychotic disorders, and which included a comparison group of healthy controls, published from 1965 to January 31, 2017...
February 2018: World Psychiatry: Official Journal of the World Psychiatric Association (WPA)
https://www.readbyqxmd.com/read/29316290/a-3d-bioprinted-in-situ-conjugated-co-fabricated-scaffold-for-potential-bone-tissue-engineering-applications
#8
Mduduzi N Sithole, Pradeep Kumar, Lisa C du Toit, Thashree Marimuthu, Yahya E Choonara, Viness Pillay
There is a demand for progressive approaches in bone tissue engineering to repair and regenerate bone defects resulting from trauma or disease. This investigation sought to engineer a single-step in situ conjugated polymeric scaffold employing 3D printing technology as an innovative fabricating tool. A polymeric scaffold was engineered in situ employing sodium alginate as a bio-ink which interacted with a poly(ethyleneimine) solution on bioprinting to form a polyelectrolyte complex through ionic bond formation...
January 9, 2018: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/29310353/complex-pelvic-ring-injuries-associated-with-floating-knee-in-a-poly-trauma-patient-a-case-report
#9
Yuebin Zhou, Honggang Guo, Zhiwei Cai, Yuan Zhang
RATIONALE: Complex pelvic ring fracture associated with floating knee is comparatively rare which usually results from high-energy trauma including vehicle-related accidence, falls from height, and earthquake-related injury. To our knowledge, few literatures have documented such injuries in the individual patient. Management of both injuries present challenges for surgical management and postoperative care. The purpose of this study is to prove the feasibility and benefits of damage control orthopedics (DCO)...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29285982/effects-of-veliparib-on-microglial-activation-and-functional-outcomes-following-traumatic-brain-injury-in-the-rat-and-pig
#10
Karen Irvine, Robin Bishop, Seok Joon Won, Jianguo Xu, Katherine Hamel, Valerie Coppes, Pardeep Singh, Andrew Sondag, Eric Rome, Jayinee Basu, Giordano Santos, S Scott Panter, Raymond Swanson
The inflammation response induced by brain trauma can impair recovery. This response requires several hours to fully develop, and thus provides a clinically relevant therapeutic window of opportunity. Poly(ADP-ribose) polymerase inhibitors suppress inflammatory responses, including brain microglial activation. Here we evaluated delayed treatment with veliparib, a poly(ADP-ribose) polymerase inhibitor currently in clinical trials as a cancer therapeutic, in rats and pigs subjected to controlled cortical impact (CCI)...
December 29, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/29284546/medical-emergencies-related-to-ethanol-and-illicit-drugs-at-an-annual-nocturnal-indoor-electronic-dance-music-event
#11
Paul Calle, Nora Sundahl, Kristof Maudens, Sarah Mr Wille, Diederik Van Sassenbroeck, Koen De Graeve, Stefan Gogaert, Peter De Paepe, Dieter Devriese, Geert Arno, Peter Blanckaert
Introduction Medical problems are frequently encountered during electronic dance music (EDM) events. Problem There are uncertainties about the frequencies and severity of intoxications with different types of recreational drugs: ethanol, "classical" illicit party drugs, and new psychoactive substances (NPS). METHODS: Statistical data on the medical problems encountered during two editions of an indoor electronic dance event with around 30,000 attendants were retrieved from the Belgian Red Cross (Mechelen, Belgium) database...
December 29, 2017: Prehospital and Disaster Medicine
https://www.readbyqxmd.com/read/29261592/whole-blood-and-hextend-bookends-of-modern-tactical-combat-casualty-care-field-resuscitation-and-starting-point-for-multi-functional-resuscitation-fluid-development
#12
Forest R Sheppard, Thomas A Mitchell, Antoni R Macko, Darren M Fryer, Leasha J Schaub, Kassandra M Ozuna, Jacob J Glaser
BACKGROUND: Hemorrhage is the leading cause of preventable death in traumatically injured civilian and military populations. Pre-hospital resuscitation largely relies on crystalloid and colloid intra-vascular expansion, as whole blood and component blood therapy are logistically arduous. In this experiment, we evaluated the bookends of Tactical Combat Casualty Care Guidelines recommendations of pre-hospital resuscitation with Hextend and whole blood in a controlled hemorrhagic shock model within non-human primates, as means of a multi-functional resuscitative fluid development...
December 20, 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/29240805/poly-victimization-in-a-norwegian-adolescent-population-prevalence-social-and-psychological-profile-and-detrimental-effects
#13
Svein Mossige, Lihong Huang
BACKGROUND: This study focuses on poly-victimization, with the aim of providing a realistic estimation of the prevalence of lifetime victimization in a Norwegian adolescent population (ages 18-19 years). METHODS: Based upon the concept from previous research, we applied measures of child poly-victimization on Norwegian data obtained from a national youth survey in 2015 (N = 4,531) to arrive at an estimation of its prevalence. We used variables that measure individual characteristics such as gender and educational aspiration and socio-economic factors such as parents' education level and home economic situation to derive a social and psychological profile of victimization and poly-victimization among young people...
2017: PloS One
https://www.readbyqxmd.com/read/29208274/hemostatic-porous-sponges-of-cross-linked-hyaluronic-acid-cationized-dextran-by-one-self-foaming-process
#14
Jia-Ying Liu, Yang Li, Yang Hu, Gang Cheng, Enyi Ye, Chuanan Shen, Fu-Jian Xu
Effective hemostatic materials are very important for treating trauma cases. Natural polysaccharides have been particularly appealing in the development of new hemostatic materials due to their unique functions in human bodies. In this work, different polysaccharide-based hemostatic porous sponges (SHDP or SHDQ) of cross-linked hyaluronic acid (HA)/cationized dextran were readily prepared by the self-foaming process of HA and poly((2-dimethyl amino)-ethyl methacrylate)-grafted dextran (Dex-PDM) or partially-quaternized Dex-PDM in the presence of sodium trimetaphosphate crosslinkers...
February 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/29196042/multilayer-polyion-complex-nanoformulations-of-superoxide-dismutase-1-for-acute-spinal-cord-injury
#15
N V Nukolova, A D Aleksashkin, T O Abakumova, A Y Morozova, I L Gubskiy, Е А Kirzhanova, M A Abakumov, V P Chekhonin, N L Klyachko, A V Kabanov
As one of the most devastating forms of trauma, spinal cord injury (SCI) remains a challenging clinical problem. The secondary processes associated with the primary injury, such as overproduction of reactive oxygen species (ROS) and inflammation, lead to concomitant compression of the injured spinal cord and neuronal death. Delivery of copper-zinc superoxide dismutase (SOD1), an efficient ROS scavenger, to the site of injury can mitigate SCI-induced oxidative stress and tissue damage. Towards this goal catalytically active nanoformulations of SOD1 ("nanozymes") are developed as a modality for treatment of SCI...
November 28, 2017: Journal of Controlled Release: Official Journal of the Controlled Release Society
https://www.readbyqxmd.com/read/29188335/poly-traumatic-multi-ligament-knee-injuries-is-the-knee-the-limiting-factor
#16
Jarret M Woodmass, Nick R Johnson, Rohith Mohan, Aaron J Krych, Bruce A Levy, Michael J Stuart
PURPOSE: Multi-ligament knee injuries (MLKI) from a high-velocity accident are rare but potentially devastating. This matched cohort analysis compares knee functional outcomes after multiple ligament reconstruction in poly-trauma patients to those that occurred in isolation. METHODS: Sixty-two patients with MLKI that occurred either as a component of polytrauma or had occurred in isolation were matched according to age, sex, and knee dislocation grade. Functional outcomes and knee physical examination were assessed at a 2-year follow-up...
November 29, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/29156357/generation-of-complement-molecular-complex-c5b-9-c5b-9-in-response-to-poly-traumatic-hemorrhagic-shock-and-evaluation-of-c5-cleavage-inhibitors-in-non-human-primates
#17
R Madelaine Paredes, Sarah Reyna, Philip Vernon, Douglas K Tadaki, Jurandir J Dallelucca, Forest Sheppard
Severe trauma initiates a systemic inflammatory cascade and that involves early activation of complement and cleavage of C5 into C5a (anaphylatoxin) and C5b (C5b-9 membrane attack complex). We examined activation of C5 in non-human primate (NHP) models of hemorrhagic shock. Blood plasma concentrations of C5b-9 were significantly increased in NHPs in response to hemorrhage alone and were further increased with the addition of tissue trauma. The onset of increased C5 cleavage was accelerated in NHPs that experienced decompensated poly-traumatic hemorrhagic shock...
January 2018: International Immunopharmacology
https://www.readbyqxmd.com/read/29103492/a-composite-hydrogel-of-chitosan-heparin-poly-%C3%AE-glutamic-acid-loaded-with-superoxide-dismutase-for-wound-healing
#18
Lin Zhang, Yina Ma, Xiaochen Pan, Siyuan Chen, Huahong Zhuang, Shufang Wang
In chronic wounds, severe oxidative stress hampers the healing of wounds. This study constructed a novel antioxidant-loaded hydrogel for healing diabetic wounds. First, composite hydrogels consisting of chitosan, heparin and poly (γ-glutamic acid) with different ratios were prepared through electrostatic interaction. These hydrogels exhibited good three-dimensional network structures, and the porosity of the hydrogels decreased as the crosslinking density increased. The hydrogels possessed good swelling capacity, and showed typical viscoelastic behavior and good mechanical property in rheological test...
January 15, 2018: Carbohydrate Polymers
https://www.readbyqxmd.com/read/29072193/development-of-poly-1-8-octanediol-co-citrate-and-poly-acrylic-acid-nanofibrous-scaffolds-for-wound-healing-applications
#19
Allison Goins, Vidhya Ramaswamy, Elliott Dirr, Krista Dulany, Sean Irby, Antonio Webb, Josephine Allen
Wound care is one of the leading health care problems in the United States costing billions of dollars yearly. Annually, millions of acute wounds occur due to surgical procedures or traumas such as burns and abrasions, and these wounds can become non-healing due to bacterial infection or underlying pathologies. Current wound care treatments include the use of bioinert constructs combined with topical administration of anti-bacterial agents and growth factors. However, there is a growing need for the development of bioactive wound dressing materials that are able to promote wound healing and the regeneration of healthy tissue...
October 26, 2017: Biomedical Materials
https://www.readbyqxmd.com/read/29018873/the-treatment-of-perilunate-ligament-injuries-in-multiply-injured-patients
#20
K V Brown, D Tsekes, C G Gorgoni, L Di Mascio
PURPOSE: Perilunate injuries are rare, severe injuries of the carpus. They can present as isolated injuries or in the poly-traumatised patient. This is the first documented series of these injuries treated in a Major Trauma Centre. The aims were to assess the management, treatment algorithm and outcomes, of perilunate injuries in our department, review whether concomitant polytrauma affected those outcomes and identify if delay to definitive treatment had a significant effect on overall outcome...
October 10, 2017: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
keyword
keyword
95217
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"