Donagh Healy, Mary Clarke-Moloney, Brendan Gaughan, Siobhan O'Daly, Derek Hausenloy, Faisal Sharif, John Newell, Martin O'Donnell, Pierce Grace, John F Forbes, Walter Cullen, Eamon Kavanagh, Paul Burke, Simon Cross, Joseph Dowdall, Morgan McMonagle, Greg Fulton, Brian J Manning, Elrasheid A H Kheirelseid, Austin Leahy, Daragh Moneley, Peter Naughton, Emily Boyle, Seamus McHugh, Prakash Madhaven, Sean O'Neill, Zenia Martin, Donal Courtney, Muhammed Tubassam, Sherif Sultan, Damian McCartan, Mekki Medani, Stewart Walsh
BACKGROUND: Patients undergoing vascular surgery procedures constitute a 'high-risk' group. Fatal and disabling perioperative complications are common. Complications arise via multiple aetiological pathways. This mechanistic redundancy limits techniques to reduce complications that target individual mechanisms, for example, anti-platelet agents. Remote ischaemic preconditioning (RIPC) induces a protective phenotype in at-risk tissue, conferring protection against ischaemia-reperfusion injury regardless of the trigger...
April 23, 2015: Trials