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https://www.readbyqxmd.com/read/28431589/t2-relaxometry-helps-prognosticate-seizure-outcome-in-patients-with-solitary-cerebral-cysticercosis
#1
Aaron de Souza, Atchayaram Nalini, Jitender Saini, Kandavel Thennarasu
OBJECTIVE: Correlate serial T2 relaxometry (T2R) values with long term seizure outcome in patients with solitary cerebral cysticercosis (SCC) in order to establish its usefulness as a prognostic marker in these patients. METHODS: Patients with new-onset seizures due to SCC were imaged serially using a pre-determined MRI protocol at enrolment and after 3, 6, 12 and 24months. T2 relaxometry was performed using a dual echo sequence with maps generated manually from the measured image intensities at the level of the lesion...
May 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28419804/simultaneous-reconstruction-of-the-medial-and-lateral-collateral-ligaments-for-chronic-combined-ligament-injuries-of-the-ankle
#2
Toshito Yasuda, Hiroaki Shima, Katsunori Mori, Seiya Tsujinaka, Masashi Neo
BACKGROUND: Objective data on chronic injuries of the medial collateral ligament (MCL) of the ankle are scarce. Chronic MCL injuries are frequently associated with lateral collateral ligament (LCL) injuries. For patients with chronic combined MCL and LCL injuries, the authors have performed simultaneous surgery of the 2 ligaments. HYPOTHESIS: Simultaneous surgery of the 2 ligaments may be effectively used to treat chronic combined MCL and LCL injuries. STUDY DESIGN: Case series; Level of evidence, 4...
April 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28419613/peg-poly-l-lysine-based-polymeric-micelle-mri-contrast-agent-feasibility-study-of-a-gd-micelle-contrast-agent-for-mr-lymphography
#3
Hiroyuki Akai, Kouichi Shiraishi, Masayuki Yokoyama, Koichiro Yasaka, Masanori Nojima, Yusuke Inoue, Osamu Abe, Kuni Ohtomo, Shigeru Kiryu
PURPOSE: To investigate the feasibility of polymeric micelle of poly(ethyleneglycol) (PEG)-b-poly(L-lysine-DOTA) (Gd-micelle) as a contrast agent for magnetic resonance lymphography (MRL). MATERIALS AND METHODS: Twenty-four female BALB/c mice were randomly divided into four groups of six mice each. Among them, mice of two groups were injected of complete Freund's adjuvant to obtain inflamed lymph nodes. We subcutaneously injected 0.5 μmol Gd per mouse of Gd-micelle or gadofluorine P in the right rear footpad...
April 17, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28409222/incidental-splenic-nodules-found-on-mr-imaging-done-for-assessment-of-iron-overload-in-children
#4
Rayan A Ahyad, Christopher Z Lam, Omid Shearkhani, Oscar M Navarro
BACKGROUND: MR imaging is used to assess iron overload in patients with hemoglobinopathies and in those who have undergone multiple blood transfusions. Sometimes splenic nodules are found incidentally on these examinations and this may cause diagnostic uncertainty. OBJECTIVE: To determine the prevalence, imaging characteristics and evolution of splenic nodules found on MR imaging for iron overload evaluation. MATERIALS AND METHODS: Retrospective review of all MR imaging examinations performed for iron overload assessment from 2005 to 2015 in a tertiary pediatric hospital...
April 13, 2017: Pediatric Radiology
https://www.readbyqxmd.com/read/28408633/heterogeneity-of-cortical-lesion-susceptibility-mapping-in-multiple-sclerosis
#5
M Castellaro, R Magliozzi, A Palombit, M Pitteri, E Silvestri, V Camera, S Montemezzi, F B Pizzini, A Bertoldo, R Reynolds, S Monaco, M Calabrese
BACKGROUND AND PURPOSE: Quantitative susceptibility mapping has been used to characterize iron and myelin content in the deep gray matter of patients with multiple sclerosis. Our aim was to characterize the susceptibility mapping of cortical lesions in patients with MS and compare it with neuropathologic observations. MATERIALS AND METHODS: The pattern of microglial activation was studied in postmortem brain tissues from 16 patients with secondary-progressive MS and 5 age-matched controls...
April 13, 2017: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/28402868/age-related-differences-in-twitch-properties-and-muscle-activation-of-the-first-dorsal-interosseous
#6
Jonathan D Miller, Trent J Herda, Michael A Trevino, Adam J Sterczala, Anthony B Ciccone, Justin X Nicoll
OBJECTIVE: To examine twitch force potentiation and twitch contraction duration, as well as electromyographic amplitude (EMGRMS) and motor unit mean firing rates (MFR) at targeted forces between young and old individuals in the first dorsal interosseous (FDI). Ultrasonography was used to assess muscle quality. METHODS: Twenty-two young (YG) (age=22.6±2.7years) and 14 older (OD) (age=62.1±4.7years) individuals completed conditioning contractions at 10% and 50% maximal voluntary contraction, (MVC) during which EMGRMS and MFRs were assessed...
March 24, 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/28397384/characteristics-and-effectiveness-of-vasodilatory-and-pressor-compensation-for-reduced-relaxation-time-during-rhythmic-forearm-contractions
#7
Robert F Bentley, Veronica J Poitras, Terrence Hong, Michael E Tschakovsky
During muscle contraction in rhythmic exercise muscle blood flow is significantly impeded by microvascular compression. The purpose of this study was to establish the nature and magnitude of vasodilatory and/or pressor compensatory responses during forearm exercise in the face of an increased duration of mechanical microvascular compression, and whether the effectiveness of such compensation was exercise intensity dependent. Seven healthy males (21.0 ± 1.8 yrs) completed progressive forearm exercise (24...
April 10, 2017: Experimental Physiology
https://www.readbyqxmd.com/read/28395965/muscular-echovariation-a-new-biomarker-in-amyotrophic-lateral-sclerosis
#8
Jacinto J Martínez-Payá, María Elena Del Baño-Aledo, José Ríos-Díaz, José I Tembl-Ferrairó, Juan F Vázquez-Costa, Francesc Medina-Mirapeix
The purpose of the work described here was to assess the characteristics of echovariation in amyotrophic lateral sclerosis (ALS) compared with other muscle ultrasonography parameters. Twenty-six ALS patients (8 women, mean age 58.9 y, standard deviation 12.02 y) and 26 healthy controls (17 women, mean age 59.6 y, standard deviation 6.41 y) were included in this observational study. They underwent bilateral and transverse ultrasound of the biceps/brachialis, forearm flexor group, quadriceps femoris and tibialis anterior...
April 7, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28391818/a-computational-measurement-of-cartilaginous-endplate-structure-using-ultrashort-time-to-echo-mri-scanning
#9
Ri-Chu Jin, Yong-Can Huang, Keith D K Luk, Yong Hu
BACKGROUND AND OBJECTIVE: Ultrashort time-to-echo (UTE) MRI scanning has been applied to observe the cartilaginous endplate (CEP) in intervertebral disc. CEP plays a critical role in IVD health and disease. Nevertheless, current measurements of CEP based on UTE MRI technique are still by manual segmentation, and observation of signal abnormality was usually time-consuming and often disturbed by subjective bias. This study hence proposed an efficient way to harvest the global parameters of CEP after UTE MRI scanning...
May 2017: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/28382599/diagnostic-accuracy-of-quantitative-neuromuscular-ultrasound-for-the-diagnosis-of-intensive-care-unit-acquired-weakness-a-cross-sectional-observational-study
#10
Esther Witteveen, Juultje Sommers, Luuk Wieske, Jonne Doorduin, Nens van Alfen, Marcus J Schultz, Ivo N van Schaik, Janneke Horn, Camiel Verhamme
BACKGROUND: Neuromuscular ultrasound is a noninvasive investigation, which can be easily performed at the bedside on the ICU. A reduction in muscle thickness and increase in echo intensity over time have been described in ICU patients, but the relation to ICU-acquired weakness (ICU-AW) is unknown. We hypothesized that quantitative assessment of muscle and nerve parameters with ultrasound can differentiate between patients with and without ICU-AW. The aim of this cross-sectional study was to investigate the diagnostic accuracy of neuromuscular ultrasound for diagnosing ICU-AW...
December 2017: Annals of Intensive Care
https://www.readbyqxmd.com/read/28382536/follow-up-assessment-of-coiled-intracranial-aneurysms-using-zte-mra-as-compared-with-tof-mra-a-preliminary-image-quality-study
#11
Song'an Shang, Jing Ye, Xianfu Luo, Jianxun Qu, Yong Zhen, Jingtao Wu
OBJECTIVES: To prospectively assess coiled intracranial aneurysms using a novel non-contrast enhanced zero echo time (zTE) MR angiography (MRA) method, and compare its image quality with time-of-flight (TOF) MRA, using digital subtraction angiography (DSA) as reference. METHODS: Twenty-five patients (10 males and 15 females; age 53.96 ± 12.46 years) were enrolled in this monocentric study. MRA sequences were performed 24 h before DSA. Susceptibility artefact intensity and flow signal within the parent artery were carried out using a 4-point scale...
April 5, 2017: European Radiology
https://www.readbyqxmd.com/read/28380913/improving-the-performance-of-time-domain-pulsed-echo-laser-profile-using-tunable-lens
#12
Cao Jie, Yang Cheng, Qun Hao, Fanghua Zhang, Kaiyu Zhang, Xiao Li, Kun Li, Yuxin Peng
We theoretically and experimentally examined the effects of the different positions between receiving lens (RL) and detector, namely, defocus, off-axis, and tilt, on the time-domain pulsed echo laser profile (TDPELP). Results show that distortions including saturation and broadening of TDPELP are obtained, regardless of the position between RL and detector. Thus, we adjust the focal length of RL to successfully obtain an optimal TDPELP using tunable lens under extreme situations, such as too strong or too weak intensity of the TDPELP...
April 3, 2017: Optics Express
https://www.readbyqxmd.com/read/28363111/3t-hippocampal-glutamate-glutamine-complex-reflects-verbal-memory-decline-in-aging
#13
Simona Nikolova, Shauna M Stark, Craig E L Stark
The hippocampus is a critical site for alterations that are responsible for age-related changes in memory. Here, we present a relatively novel approach of examining the relationship between memory performance and glutamate-glutamine levels using short echo time magnetic resonance spectroscopy. Specifically, we investigated the relationship between Glx (a composite of glutamate and glutamine) levels in the hippocampus, performance on a word-recall task, and resting-state functional connectivity. While there was no overall difference in Glx intensity between young and aging adults, we identified a positive correlation between delayed word-list recall and Glx, bilaterally in older adults, but not in young adults...
June 2017: Neurobiology of Aging
https://www.readbyqxmd.com/read/28357568/high-resolution-metal-artifact-reduction-mr-imaging-of-the-lumbosacral-plexus-in-patients-with-metallic-implants
#14
Shivani Ahlawat, Steven E Stern, Allan J Belzberg, Jan Fritz
OBJECTIVE: To assess the quality and accuracy of metal artifact reduction sequence (MARS) magnetic resonance imaging (MRI) for the diagnosis of lumbosacral neuropathies in patients with metallic implants in the pelvis. MATERIALS AND METHODS: Twenty-two subjects with lumbosacral neuropathy following pelvic instrumentation underwent 1.5-T MARS MRI including optimized axial intermediate-weighted and STIR turbo spin echo sequences extending from L5 to the ischial tuberosity...
March 30, 2017: Skeletal Radiology
https://www.readbyqxmd.com/read/28356621/changes-in-t2-weighted-mri-of-supinator-muscle-pronator-teres-muscle-and-extensor-indicis-muscle-with-manual-muscle-testing
#15
Kazuya Yoshida, Sumikazu Akiyama, Masayoshi Takamori, Hiroshi Otsuka D Eng, Yoshiteru Seo
[Purpose] In order to detect muscle activity with manual muscle testing, T2-weighted magnetic resonance (T2w-MR) images were detected by a 0.2 T compact MRI system. [Subjects and Methods] The subjects were 3 adult males. Transverse T2-weighted multi-slice spin-echo images of the left forearm were measured by a 39 ms echo-time with a 2,000 ms repetition time, a 9.5 mm slice thickness, 1 accumulation and a total image acquisition time of 4 min 16 s. First, T2w-MR images in the resting condition were measured...
March 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28342191/exploiting-multicompartment-effects-in-triple-echo-steady-state-t2-mapping-for-fat-fraction-quantification
#16
Dian Liu, Andreas Steingoetter, Jelena Curcic, Sebastian Kozerke
PURPOSE: To investigate and exploit the effect of intravoxel off-resonance compartments in the triple-echo steady-state (TESS) sequence without fat suppression for T2 mapping and to leverage the results for fat fraction quantification. METHODS: In multicompartment tissue, where at least one compartment is excited off-resonance, the total signal exhibits periodic modulations as a function of echo time (TE). Simulated multicompartment TESS signals were synthesized at various TEs...
March 25, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28339206/utilizing-electron-spin-echo-envelope-modulation-to-distinguish-between-the-local-secondary-structures-of-an-%C3%AE-helix-and-an-amphipathic-310-helical-peptide
#17
Lauren Bottorf, Sophia Rafferty, Indra D Sahu, Robert M McCarrick, Gary A Lorigan
Electron spin echo envelope modulation (ESEEM) spectroscopy was used to distinguish between the local secondary structures of an α-helix and a 310-helix. Previously, we have shown that ESEEM spectroscopy in combination with site-directed spin labeling (SDSL) and (2)H-labeled amino acids (i) can probe the local secondary structure of α-helices, resulting in an obvious deuterium modulation pattern, where i+4 positions generally show larger (2)H ESEEM peak intensities than i+3 positions. Here, we have hypothesized that due to the unique turn periodicities of an α-helix (3...
March 31, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28331947/-magnetic-resonance-spectroscopy-of-brain-tumors
#18
P Ditter, E Hattingen
BACKGROUND: Conventional magnetic resonance imaging (MRI) under consideration of clinical information enables the correct diagnosis and therapy for the majority of cerebral space-occupying lesions. Some important differential diagnoses, e. g. low vs. high-grade tumors, require additional MRI methods. OBJECTIVE: This article critically discusses the importance of magnetic resonance spectroscopy ((1)H-MRS) in brain tumors. MATERIAL AND METHODS: The concentration of normal and pathological brain metabolites can be non-invasively measured by (1)H-MRS...
March 22, 2017: Der Radiologe
https://www.readbyqxmd.com/read/28323638/fast-lesion-mapping-during-hifu-treatment-using-harmonic-motion-imaging-guided-focused-ultrasound-hmigfus-in-vitro-and-in-vivo
#19
Yang Han, Shutao Wang, Thomas Payen, Elisa Konofagou
The successful clinical application of high intensity focused ultrasound (HIFU) ablation depends on reliable monitoring of the lesion formation. Harmonic motion imaging guided focused ultrasound (HMIgFUS) is an ultrasound-based elasticity imaging technique, which monitors HIFU ablation based on the stiffness change of the tissue instead of the echo intensity change in conventional B-mode monitoring, rendering it potentially more sensitive to lesion development. Our group has shown that predicting the lesion location based on the radiation force-excited region is feasible during HMIgFUS...
April 21, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28321637/the-time-course-of-short-term-hypertrophy-in-the-absence-of-eccentric-muscle-damage
#20
Matt S Stock, Jacob A Mota, Ryan N DeFranco, Katherine A Grue, A Unique Jacobo, Eunhee Chung, Jordan R Moon, Jason M DeFreitas, Travis W Beck
BACKGROUND: It has been proposed that the increase in skeletal muscle mass observed during the initial weeks of initiating a resistance training program is concomitant with eccentric muscle damage and edema. PURPOSE: We examined the time course of muscle hypertrophy during 4 weeks of concentric-only resistance training. METHODS: Thirteen untrained men performed unilateral concentric-only dumbbell curls and shoulder presses twice per week for 4 weeks...
March 20, 2017: European Journal of Applied Physiology
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