Read by QxMD icon Read

kawasaki disease

Najib Advani, Sudigdo Sastroasmoro, Teddy Ontoseno, Cuno Spm Uiterwaal
Background: Kawasaki disease (KD) is an acute systemic vasculitis syndrome with a high incidence of coronary aneurysms in untreated children. The majority of aneurysms resulting from KD are known to regress with time. Aims: This study aimed to determine the course and outcome of coronary artery dilatation in patients with KD and ascertain whether there are any differences in the outcomes in the different branches. Setting and Design: This is a retrospective cohort study of patients diagnosed with KD with midterm follow-up data...
May 2018: Annals of Pediatric Cardiology
Shigeomi Yokoya, Aiko Tamura, Akihiko Hino, Masamichi Bamba, Toshikazu Kato, Hidesato Takezawa, Yukihiro Goto, Hideki Oka, Akihiro Fujii
BACKGROUND: Kawasaki disease (KD) is an acute systemic vasculitis that primarily affects the coronary artery, but does not commonly affect the carotid artery. Cerebral infarction (CI) with internal carotid artery stenosis (ICS) in patients with KD had never been reported. We report a patient with CI as a remote phase complication of KD. CASE PRESENTATION: A 32-year-old man presented with impaired consciousness. Magnetic resonance imaging scan (MRI) and digital subtraction angiogram (DSA) confirmed CI and ICS...
June 16, 2018: World Neurosurgery
Minami Kawasaki, Jerome Delamare-Deboutteville, Rachel O Bowater, Mark J Walker, Scott Beatson, Nouri L Ben Zakour, Andrew C Barnes
Streptococcus agalactiae (GBS) causes disease in a wide range of animals. The serotype Ib lineage is highly adapted to aquatic hosts, exhibiting substantial genome reduction compared with terrestrial conspecifics. Here we sequence genomes from 40 GBS isolates including 25 from wild fish and captive stingrays in Australia, six local veterinary or human clinical isolates, and nine isolates from farmed tilapia in Honduras and compare with 42 genomes from public databases. Phylogenetic analysis based on non-recombinant core genome SNPs indicated that aquatic serotype Ib isolates from Queensland were distantly related to local veterinary and human clinical isolates...
June 18, 2018: Applied and Environmental Microbiology
Xu Guo, Xiaoou Wang, Xinzhong Zhang, Ahmed O Ahmed, David H Hsi, Daqing Zhang
BACKGROUND: Kawasaki disease is an acute febrile disease with mucocutaneous and cardiovascular involvement affecting infants and young children. Though coronary artery abnormalities are common in Kawasaki disease, no consensus has been reached regarding the treatment of acute coronary artery diseases in this population. CASE PRESENTATION: We described a case of myocardial infarction triggered by blunt chest wall trauma in a 20 years old girl. She presented with chest pain and breathlessness with brief syncope, lab results and electrocardiogram findings were consistent with acute myocardial infarction...
June 18, 2018: BMC Cardiovascular Disorders
Jung Sook Yeom, Young Hye Cho, Chung Mo Koo, Jin Su Jun, Ji Sook Park, Eun Sil Park, Ji-Hyun Seo, Jae-Young Lim, Hyang-Ok Woo, Hee-Shang Youn
Cerebral vasculitis is thought to be a possible underlying mechanism of severe neurological complications of Kawasaki's disease (KD), such as cerebral infarct or aneurysm rupture. To evaluate the intracranial inflammatory response in patients with acute-stage KD, we measured the levels of cytokines (interleukin [IL]-6 and tumor necrosis factor [TNF]-α) and pentraxin-3 (PTX3) in the cerebrospinal fluid of patients with KD ( n  = 7) and compared the levels to those of the age- and sex-matched febrile control patients (bacterial meningitis [ n  = 5], enteroviral meningitis [ n  = 10], nonspecific viral illness without central nervous system involvement [ n  = 10])...
June 18, 2018: Neuropediatrics
Gauthier Blonz, Sylvie Lacroix, Nadir Benbrik, Karine Warin-Fresse, Agathe Masseau, David Trewick, Mohamed Hamidou, Jean-Louis Stephan, Antoine Néel
No abstract text is available yet for this article.
June 15, 2018: Journal of Clinical Rheumatology: Practical Reports on Rheumatic & Musculoskeletal Diseases
Liliana Tavares, Conceição Calhau, Jorge Polónia
INTRODUCTION: The migration of African populations to Europe poses problems of adaptation that may increase the risk of cardiovascular disease. We assessed the cardiovascular risk of Cape Verdean university students studying in Portugal (CV-PT) compared to Cape Verdean university students in Cape Verde (CV-CV) and to Caucasian university students in Portugal (PT-PT). METHODS: A cross-sectional study was performed comparing three university populations, 54-62% female, aged 19-28 years: CV-PT (n=104), CV-CV (n=100) and PT-PT (n=100)...
June 14, 2018: Portuguese Journal of Cardiology: An Official Journal of the Portuguese Society of Cardiology
Li Zhang, Jinxin Wang, Di Che, Yanfei Wang, Xing Rong, Lei Pi, Yufen Xu, Wei Li, Ping Huang, Maoping Chu, Xiaoqiong Gu
miRNA-146a plays a critical role in innate immune and inflammatory responses. Kawasaki disease involves immune-mediated inflammatory responses, which lead to vascular endothelial injury. However, there has been no study on the association between the miRNA-146a rs2910164 C>G polymorphism and Kawasaki disease risk. We enrolled 532 Kawasaki disease patients and 623 healthy controls from a southern Chinese population, and the miRNA-146a rs2910164 C>G polymorphism was genotyped by the TaqMan method. There was no evidence that this polymorphism was associated with Kawasaki disease...
June 14, 2018: Bioscience Reports
Jae Yun Jung, Eun Mi Ham, Hyuksool Kwon, Young Ho Kwak, Do Kyun Kim, Jin Hee Lee, Jin Hee Jung
BACKGROUND: Coronary artery dilatation (CAD) is a great concern with Kawasaki disease (KD). This study aimed to investigate the relationship between serum N-terminal pro-brain natriuretic peptide (NT-proBNP) levels and CAD in patients with the hyperacute phase (≤4 days of fever) of KD. METHODS: Serum NT-proBNP levels were compared between patients with and those without CAD, who underwent transthoracic echocardiography (TTE) within 24 h of the hyperacute phase of KD in the pediatric emergency department (PED)...
June 8, 2018: American Journal of Emergency Medicine
Toshiki Kuno, Akimichi Shibata, Masaki Kodaira, Yohei Numasawa
No abstract text is available yet for this article.
June 12, 2018: Circulation Journal: Official Journal of the Japanese Circulation Society
Kimya Hassani-Ardakani, Thusanth Thuraisingam, Duc-Vinh Thai, Rayan Alkhodair, Van-Hung Nguyen, Sarah Campillo, Barbara Miedzybrodzki, Fatemeh Jafarian
No abstract text is available yet for this article.
July 2018: JAAD Case Reports
Luisa Berenise Gamez-Gonzalez, Isabel Moribe-Quintero, Martin Cisneros-Castolo, Javier Varela-Ortiz, Mireya Muñoz-Ramírez, Martin Garrido-García, Marco Yamazaki-Nakashimada
BACKGROUND: Kawasaki disease shock syndrome (KDSS) is an uncommon presentation of Kawasaki disease (KD). KDSS has been associated with more severe markers of inflammation, coronary abnormalities and IVIG resistance. METHODS: A retrospective, descriptive study of children with KDSS in two hospitals was performed. Relevant articles about KD and shock were collected, demographic data, clinical presentation, laboratory variables, echocardiogram findings, treatment and special features were analyzed when available...
June 11, 2018: Pediatrics International: Official Journal of the Japan Pediatric Society
R Y Gou, F Wang, X Y Dong
No abstract text is available yet for this article.
June 2, 2018: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
Isabelle Koné-Paut, Rolando Cimaz, Jethro Herberg, Oliver Bates, Aurelia Carbasse, Jean Pierre Saulnier, Maria Cristina Maggio, Jordi Anton, Maryam Piram
OBJECTIVES: To identify the clinical characteristics, reasons for use and response to treatment with anakinra in a series of patients with Kawasaki Disease (KD). STUDY DESIGN: A retrospective chart review of patients treated with anakinra for KD diagnosed according to the AHA criteria. We compared clinical, biological and echocardiographic characteristics of KD before and after anakinra use. We analysed reasons for use of anakinra, and compared treatment regimens used in 7 European KD referral centres...
June 6, 2018: Autoimmunity Reviews
Nobuhito Abe, Iori Kawasaki, Hiroaki Hosokawa, Toru Baba, Atsushi Takeda
Parkinson's disease (PD) is a common neurodegenerative disorder characterized by loss of dopamine neurons. Since a seminal report was published in the early twentieth century, a growing body of literature has suggested that patients with PD display characteristic personality traits, such as cautiousness and inflexibility. Notably, PD patients have also been described as "honest," indicating that they have a remarkable tendency to avoid behaving dishonestly. In this study, we predicted that PD patients show reduced cheating behavior in opportunities for dishonest gain due to dysfunction of the dopaminergic reward system...
2018: Frontiers in Neurology
Yufeng Zhang, Han Wan, Maosheng Du, Huiling Deng, Jia Fu, Yu Zhang, Xiaoyan Wang, Ruiqing Liu
RATIONALE: Kawasaki disease (KD) is an acute vasculitis of childhood, coronary complications are the most serious and classic complications of this disease. However, simultaneous complications such as systemic capillary leak syndrome (CLS) and aseptic meningitis are rarely reported. PATIENT CONCERNS: A 19-month-old boy had continuous fever for 6 days, rash for 3 days, and somnolence for 1 day. DIAGNOSES: The boy was diagnosed with KD presenting with SCLS and aseptic meningitis...
June 2018: Medicine (Baltimore)
Motoi Kobayashi, Tomohiro Suhara, Yuichi Baba, Nicholas K Kawasaki, Jason K Higa, Takashi Matsui
Iron is an essential mineral required for a variety of vital biological functions. Despite being vital for life, iron also has potentially toxic aspects. Iron has been investigated as a risk factor for coronary artery disease (CAD), however iron's toxicity in CAD patients still remains controversial. One possible mechanism behind the toxicity of iron is "ferroptosis", a newly described form of iron-dependent cell death. Ferroptosis is an iron-dependent form of regulated cell death that is distinct from apoptosis, necroptosis, and other types of cell death...
June 4, 2018: Current Drug Targets
Lei Pi, Di Che, Haifeng Long, Zhenzhen Fang, Jiawen Li, Shuyi Lin, Yunfeng Liu, Meiai Li, Lijuan Bao, Wenli Li, Yuan Zhang, Qiulian Deng, Techang Liu, Li Zhang, Xiaoqiong Gu
Introduction: Kawasaki disease is a kind of systemic vasculitis that mainly damages moderate and small-sized blood vessels, and is a leading cause of coronary artery lesions (CAL). Antiplatelet therapy is a routine component of Kawasaki disease treatment strategies. So it is important to evaluate the antiplatelet effect of aspirin because of the individual biological variability of antiplatelet effect of aspirin. The immature platelet fraction (IPF) has attracted particular attention as it may influence the antiplatelet effect of aspirin...
2018: Drug Design, Development and Therapy
Wataru Kubota, Masataka Honda, Hirokazu Okada, Motoshi Hattori, Masayuki Iwano, Yuko Akioka, Akira Ashida, Yukihiko Kawasaki, Hideyasu Kiyomoto, Mayumi Sako, Yoshio Terada, Daishi Hirano, Mikiya Fujieda, Shouichi Fujimoto, Takao Masaki, Shuichi Ito, Osamu Uemura, Yoshimitsu Gotoh, Yasuhiro Komatsu, Shinichi Nishi, Mitsue Maru, Ichiei Narita, Shoichi Maruyama
No abstract text is available yet for this article.
June 4, 2018: Clinical and Experimental Nephrology
Satoshi Murakami, Yuichi Tasaka, Shingo Takatori, Akihiro Tanaka, Hiromu Kawasaki, Hiroaki Araki
Ulcerative colitis (UC) is a refractory disease that causes chronic inflammation or ulceration in the mucosa of the large intestine with multiple relapses. Although several drugs, including 5-aminosalicylic acid, steroids, immunosuppressants, and infliximab, are used for UC therapy, patients suffer from side effects of these drugs, and a new safer therapeutic agent is desired. Eucommia ulmoides OLIV. leaf extract (ELE) has an anti-inflammatory effect. Therefore, we examined the effect of ELE on UC using a chronic dextran sulfate sodium (DSS)-induced colitis model in mice...
2018: Biological & Pharmaceutical Bulletin
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"