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Ear anatomy and pathology

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https://www.readbyqxmd.com/read/29544621/la-ferrassie-1-new-perspectives-on-a-classic-neandertal
#1
Asier Gómez-Olivencia, Rolf Quam, Nohemi Sala, Morgane Bardey, James C Ohman, Antoine Balzeau
The La Ferrassie 1 (LF1) skeleton, discovered over a century ago, is one of the most important Neandertal individuals both for its completeness and due to the role it has played historically in the interpretation of Neandertal anatomy and lifeways. Here we present new skeletal remains from this individual, which include a complete right middle ear ossicular chain (malleus, incus, and stapes), three vertebral fragments, and two costal remains. Additionally, the study of the skeleton has allowed us to identify new pathological lesions, including a congenital variant in the atlas, a greenstick fracture of the left clavicle, and a lesion in a mid-thoracic rib of unknown etiology...
April 2018: Journal of Human Evolution
https://www.readbyqxmd.com/read/29531882/creating-a-student-centered-learning-environment-implementation-of-problem-based-learning-to-teach-microbiology-to-undergraduate-medical-students
#2
Venkataramana Kandi, Parimala Reddy Basireddy
Introduction Medical education involves training necessary to become a physician or a surgeon. This includes various levels of training like undergraduate, internship, and postgraduate training. Medical education can be quite complex, since it involves training in pre-clinical subjects (anatomy, physiology, biochemistry), the para-clinical subjects (microbiology, pathology, pharmacology, and forensic medicine), and a discrete group of clinical subjects that include general medicine, surgery, obstetrics and gynaecology, ear, nose and throat specialization, paediatrics, cardiology, pulmonology, dermatology, ophthalmology, and orthopaedics, and many other clinical specializations and super specialities (cardio-thoracic surgery, neurosurgery, etc...
January 5, 2018: Curēus
https://www.readbyqxmd.com/read/29490361/a-pilot-study-to-investigate-the-relationship-between-interaural-differences-in-temporal-bone-anatomy-and-normal-variations-in-caloric-asymmetry
#3
David Carpenter, David Kaylie, Erin Piker, Dennis Frank-Ito
Purpose: This study assesses interaural differences in temporal bone anatomy in subjects with normal caloric findings. Method: Eligible patients included those referred to the Duke University Medical Center otology clinic complaining of dizziness, with a head computed tomography scan and caloric stimulation results within normal ranges (inter-ear difference ≤ 10% or < 25% unilateral weakness). Three-dimensional reconstructions of computed tomography scans in 11 patients were used to calculate the surface area and volume of lateral semicircular canals (LSCCs), mastoid airspaces, mastoid bones, and internal auditory canal diameter and circumference...
March 8, 2018: American Journal of Audiology
https://www.readbyqxmd.com/read/29169906/limits-on-normal-cochlear-third-windows-provided-by-previous-investigations-of-additional-sound-paths-into-and-out-of-the-cat-inner-ear
#4
John J Rosowski, Peter Bowers, Hideko H Nakajima
While most models of cochlear function assume the presence of only two windows into the mammalian cochlea (the oval and round windows), a position that is generally supported by several lines of data, there is evidence for additional sound paths into and out of the inner ear in normal mammals. In this report we review the existing evidence for and against the 'two-window' hypothesis. We then determine how existing data and inner-ear anatomy restrict transmission of sound through these additional sound pathways in cat by utilizing a well-tested model of the cat inner ear, together with anatomical descriptions of the cat cochlear and vestibular aqueducts (potential additional windows to the cochlea)...
November 10, 2017: Hearing Research
https://www.readbyqxmd.com/read/29121375/management-of-benign-middle-ear-tumors-a-series-of-7-cases
#5
Z Jason Qian, Amy M Coffey, Kathleen M O'Toole, Anil K Lalwani
Benign middle ear tumors represent a rare group of neoplasms that vary widely in their pathology, anatomy, and clinical findings. These factors have made it difficult to establish guidelines for the resection of such tumors. Here we present 7 unique cases of these rare and diverse tumors and draw from our experience to recommend optimal surgical management. Based on our experience, a postauricular incision is necessary in nearly all cases. Mastoidectomy is required for tumors that extend into the mastoid cavity...
October 2017: Ear, Nose, & Throat Journal
https://www.readbyqxmd.com/read/29080146/use-of-narrow-band-imaging-and-4k-technology-in-otology-and-neuro-otology-preliminary-experience-and-feasibility-study
#6
Henry Zhang, Phui Yee Wong, Tiarnan Magos, Jabin Thaj, Gaurav Kumar
The advent of the endoscope has facilitated otological surgery in recent years. Advances in optical technology have led to the development of high definition visualisation, such as 4K magnification. Narrow band imaging (NBI) has been shown to improve visualisation of tissue based on varying degrees of vascularity. This is a feasibility study, the first of its kind, aiming to investigate the appearances of middle ear anatomy and pathology (tympanic membrane, tympanosclerosis, cholesteatoma, granulation, endolymphatic sac hydrops, otosclerosis) under the NBI filter, using a high definition 4K endoscope...
January 2018: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29068930/lymphatic-territories-lymphosomes-in-the-rat-an-anatomical-study-for-future-lymphatic-research
#7
Hiroo Suami, Mario F Scaglioni
BACKGROUND: Understanding the precise anatomy in experimental animals is crucial for correct design of research projects. Rats are commonly used for scientific research in plastic surgery because of their availability in academic institutions, moderate cost, and sizable vessels for microsurgical procedures. In past publications about rat anatomy, lymphatic mapping has been limited and incomplete. The aim of this study was to comprehensively map the superficial lymphatic system in the rat...
November 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29056463/a-high-jugular-bulb-and-poor-development-of-perivestibular-aqueductal-air-cells-are-not-the-cause-of-endolymphatic-hydrops-in-patients-with-m%C3%A3-ni%C3%A3-re-s-disease
#8
Ryohei Oya, Takao Imai, Takashi Sato, Atsuhiko Uno, Yoshiyuki Watanabe, Suzuyo Okazaki, Yumi Ohta, Tadashi Kitahara, Arata Horii, Hidenori Inohara
OBJECTIVE: The presence of endolymphatic hydrops in the inner ear, which can be detected with gadolinium-enhanced magnetic resonance imaging (Gd-MRI), is widely recognized as the main pathological cause of Ménière's disease (MD). However, the precise mechanisms underlying the development of endolymphatic hydrops remains unclear. One hypothesis proposes a relationship between the presence of a high jugular bulb (HJB) and MD, which disrupts the vestibular aqueduct leading to the development of endolymphatic hydrops...
October 19, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/28551749/neuroanatomy-and-neuropathology-of-autism-spectrum-disorder-in-humans
#9
Christine Ecker, Michael J Schmeisser, Eva Loth, Declan G Murphy
Autism spectrum disorder (ASD) is a lifelong heterogeneous neurodevelopmental condition that is associated with differences in brain anatomy and connectivity. Yet, the molecular and cellular mechanisms that underpin the atypical developmental of the brain in ASD remain poorly understood. Here, we review the findings of in vivo neuroimaging studies examining the time course of atypical brain development in ASD and relate the different neurodevelopmental stages that are atypical in ASD to the known neurobiological mechanisms that drive the maturation of the typically developing brain...
2017: Advances in Anatomy, Embryology, and Cell Biology
https://www.readbyqxmd.com/read/28397138/middle-fossa-approach-for-resection-of-vestibular-schwannoma
#10
Gmaan Alzhrani, Clough Shelton, William T Couldwell
BACKGROUND: Surgical approaches for removal of vestibular schwannoma are done through retrosigmoid, translabyrinthine, or middle fossa approaches, depending on the tumor size, preoperative hearing status, surgical team experience, and patient preference. The middle fossa approach (MFA) for the vestibular schwannoma (VS) route preserves hearing and can be done with minimal morbidity and mortality. METHOD: The authors discuss the surgical anatomy of the middle fossa, internal auditory canal localization techniques, MFA indications and the procedure for VS removal, and outcome...
June 2017: Acta Neurochirurgica
https://www.readbyqxmd.com/read/28372527/panel-2-anatomy-eustachian-tube-middle-ear-and-mastoid-anatomy-physiology-pathophysiology-and-pathogenesis
#11
REVIEW
Cuneyt M Alper, Michal Luntz, Haruo Takahashi, Samir N Ghadiali, J Douglas Swarts, Miriam S Teixeira, Zsuzsanna Csákányi, Noam Yehudai, Romain Kania, Dennis S Poe
Objective In this report, we review the recent literature (ie, past 4 years) to identify advances in our understanding of the middle ear-mastoid-eustachian tube system. We use this review to determine whether the short-term goals elaborated in the last report were achieved, and we propose updated goals to guide future otitis media research. Data Sources PubMed, Web of Science, Medline. Review Methods The panel topic was subdivided, and each contributor performed a literature search within the given time frame...
April 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28229056/experimental-visualization-of-labyrinthine-structure-with-optical-coherence-tomography
#12
Saleh Mohebbi, Marjan Mirsalehi, Lüder-Alexander Kahrs, Tobias Ortmaier, Thomas Lenarz, Omid Majdani
INTRODUCTION: Visualization of inner ear structures is a valuable strategy for researchers and clinicians working on hearing pathologies. Optical coherence tomography (OCT) is a high-resolution imaging technology which may be used for the visualization of tissues. In this experimental study we aimed to evaluate inner ear anatomy in well-prepared human labyrinthine bones. MATERIALS AND METHODS: Three fresh human explanted temporal bones were trimmed, chemically decalcified with ethylenediaminetetraacetic acid (EDTA), and mechanically drilled under visual control using OCT in order to reveal the remaining bone shell...
January 2017: Iranian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/28070244/assessment-of-fetus-during-second-trimester-ultrasonography-using-hdlive-software-what-is-its-real-application-in-the-obstetrics-clinical-practice
#13
Gabriele Tonni, Gianpaolo Grisolia, Eduardo Félix Santana, Edward Araujo Júnior
AIM: To show imaging results from application of four-dimensional (4D) ultrasound lightening technique (HDlive™) in clinical obstetrics practice. METHODS: Normal and abnormal fetuses at second and third trimester of pregnancy undergoing routine scan with 4D HDlive™ (5DUS) in the rendering mode are described. Realistic features of fetal structures were provided by 5DUS in the rendering mode. Normal anatomy as well as pathology like cleft lip, hypoplastic face, micrognathia, low-set ears, corpus callosum, arthrogryposis, aortic arch, left congenital diaphragmatic hernia are highlighted in this study...
December 28, 2016: World Journal of Radiology
https://www.readbyqxmd.com/read/27932858/one-stage-bone-strip-reconstruction-technique-with-balloon-sinus-dilatation-surgery-for-chronic-maxillary-atelectasis
#14
Tomoyuki Kashima, Robert A Goldberg, Jocelyne C Kohn, Daniel B Rootman
PURPOSE: Chronic maxillary atelectasis is characterized by unilateral spontaneous enophthalmos and hypoglobus due to increased orbital volume secondary to maxillary sinus inward deformation. Reformation of the sinus architecture and reconstruction of the orbit are key to a successful outcome. Here, we introduce a one-staged surgery that addresses both these goals. PATIENTS AND METHODS: We retrospectively reviewed 11 patients treated with one-stage orbital and sinus surgery...
2016: Clinical Ophthalmology
https://www.readbyqxmd.com/read/27891421/imaging-modality-of-choice-for-pre-operative-cochlear-imaging-hrct-vs-mri-temporal-bone
#15
Poornima Digge, Rajendra N Solanki, Dipali C Shah, Rajesh Vishwakarma, Sandeep Kumar
INTRODUCTION: Congenital inner ear malformations occur as a result of the arrest or aberrance of inner ear development due to the heredity, gene mutation or other factors. Ever since the availability of cochlear implants, pre-operative evaluation by imaging of temporal bone has gained much attention. Precise selection of the candidate for cochlear implant dependent on preoperative radiological investigations. Only CT (Computed Tomography) and MRI (Magnetic Resonance Imaging) can provide a better picture of anatomy and pathology...
October 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27752754/visualization-of-anatomy-in-normal-and-pathologic-middle-ears-by-cone-beam-ct
#16
Christian Güldner, Isabell Diogo, Eva Bernd, Stephanie Dräger, Magis Mandapathil, Afshin Teymoortash, Hesham Negm, Thomas Wilhelm
Cone beam computed tomography (CBCT, syn. digital volume tomography = DVT) was introduced into ENT imaging more than 10 years ago. The main focus was on imaging of the paranasal sinuses and traumatology of the mid face. In recent years, it has also been used in imaging of chronic ear diseases (especially in visualizing middle and inner ear implants), but an exact description of the advantages and limitations of visualizing precise anatomy in a relevant number of patients is still missing. The data sets of CBCT imaging of the middle and inner ear of 204 patients were analyzed regarding the visualization of 18 different anatomic structures...
February 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/27659846/15-th-annual-meeting-of-the-safety-pharmacology-society-focus-on-traditional-sensory-systems
#17
Icilio Cavero, Henry Holzgrefe
INTRODUCTION: This report summarizes and comments key talks on the five traditional senses (ear, vestibular system, vision, taste, olfaction, and touch) which were delivered during the 2015 Annual Meeting of the Safety Pharmacology (SP) Society. AREAS COVERED: The functional observational battery (FOB) can detect major candidate drug liabilities only on ear, touch and vision. Anatomy, physiology, pharmacology, and pathology notions on each sensory system introduce speaker talks...
January 2017: Journal of Pharmacological and Toxicological Methods
https://www.readbyqxmd.com/read/27633610/micro-optical-coherence-tomography-of-the-mammalian-cochlea
#18
Janani S Iyer, Shelley A Batts, Kengyeh K Chu, Mehmet I Sahin, Hui Min Leung, Guillermo J Tearney, Konstantina M Stankovic
The mammalian cochlea has historically resisted attempts at high-resolution, non-invasive imaging due to its small size, complex three-dimensional structure, and embedded location within the temporal bone. As a result, little is known about the relationship between an individual's cochlear pathology and hearing function, and otologists must rely on physiological testing and imaging methods that offer limited resolution to obtain information about the inner ear prior to performing surgery. Micro-optical coherence tomography (μOCT) is a non-invasive, low-coherence interferometric imaging technique capable of resolving cellular-level anatomic structures...
2016: Scientific Reports
https://www.readbyqxmd.com/read/27588594/the-endoscopic-anatomy-of-the-middle-ear-approach-to-the-fundus-of-the-internal-acoustic-canal
#19
Noritaka Komune, Satoshi Matsuo, Koichi Miki, Albert L Rhoton
OBJECTIVE The application of the endoscope in the lateral skull base increases the importance of the middle ear cavity as the corridor to the skull base. The aim of this study was to define the middle ear as a route to the fundus (lateral end) of the internal acoustic canal and to propose feasible landmarks to the fundus. METHODS This was a cadaveric study; 34 adult cadaveric temporal bones and 2 dry bones were dissected with the aid of the endoscope and microscope to show the anatomy of the transcanal approach to the middle ear and fundus of the internal acoustic canal...
June 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/27584554/light-and-electron-microscopy-methods-for-examination-of-cochlear-morphology-in-mouse-models-of-deafness
#20
Andrew Parker, Lauren Chessum, Philomena Mburu, Jeremy Sanderson, Michael R Bowl
Mice are an invaluable model organism for the study of auditory function. Even though there are differences in size and frequency response, the anatomy and physiology of the mouse and human ear are remarkably similar. In addition, the tools available for genetic manipulation in the mouse have enabled the generation of models carrying mutations in orthologous human deafness-causing genes, helping to validate these lesions and assess their functional consequence. Reciprocally, novel gene mutations discovered to cause auditory deficits in the mouse highlight potential new loci for human hearing loss, and expand our basic knowledge of the mechanisms and pathways important for the function of the mammalian ear...
September 1, 2016: Current Protocols in Mouse Biology
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