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Romina Torres, Claudia Zajer, Marcela Menéndez, María José Canessa, Jaime Cerda, María Angélica Wietstruck, Pamela Zúñiga
INTRODUCTION: Heavy menstrual bleeding (HMB) occurs in 37% of adolescents and compromise their quality of life. OBJECTIVE: To measure the magnitude of the impact of the SME on the quality of life in adolescents. PATIENTS AND METHOD: We interviewed adolescents diagnosed with HMB between 10 and 18 years old and one of their guardians. PedsQL 4.0 generic core scale was applied to measure quality of life, its Proxy PedsQL 4.0 version was applied to the guardian and 3 more questions to adolescents about limitation of daily activities...
December 2017: Revista Chilena de Pediatría
Angelica Nakagawa Lima, Ronaldo Junio de Oliveira, Antônio Sérgio Kimus Braz, Maurício Garcia de Souza Costa, David Perahia, Luis Paulo Barbour Scott
There are two different prion conformations: (1) the cellular natural (PrPC ) and (2) the scrapie (PrPSc ), an infectious form that tends to aggregate under specific conditions. PrPC and PrPSc are widely different regarding secondary and tertiary structures. PrPSc contains more and longer β-strands compared to PrPC . The lack of solved PrPSc structures precludes a proper understanding of the mechanisms related to the transition between cellular and scrapie forms, as well as the aggregation process. In order to investigate the conformational transition between PrPC and PrPSc , we applied MDeNM (molecular dynamics with excited normal modes), an enhanced sampling simulation technique that has been recently developed to probe large structural changes...
March 15, 2018: European Biophysics Journal: EBJ
Barry H Smith, Lawrence S Gazda, Thomas J Fahey, Angelica Nazarian, Melissa A Laramore, Prithy Martis, Zoe P Andrada, Joanne Thomas, Tapan Parikh, Sudipta Sureshbabu, Nathaniel Berman, Allyson J Ocean, Richard D Hall, David J Wolf
Objective: The complexity, heterogeneity and capacity of malignant neoplastic cells and tumors for rapid change and evolution suggest that living-cell-based biological-systems approaches to cancer treatment are merited. Testing this hypothesis, the tumor marker, metabolic activity, and overall survival (OS) responses, to the use of one such system, implantable macrobeads [RENCA macrobeads (RMBs)], in phase I and IIa clinical trials in advanced, treatment-resistant metastatic colorectal cancer (mCRC) are described here...
February 2018: Chinese Journal of Cancer Research, Chung-kuo Yen Cheng Yen Chiu
Mariana Luciano de Almeida, Francine Golghetto Casemiro, Camila Tiome Baba, Diana Monteiro, Mariana Fornazieri, Natália Cerri, Daniele Frascá Martins Fernandes, Grace Angélica de Oliveira Gomes
BACKGROUND: Some studies have used the follow-up method to analyze real behavioral changes in research involving physical activity (PA) interventions. This has great scientific value; however, it is hard to apply without satisfactory resources and research funding. Little is known about how many studies have used this method to analyze PA interventions in low-income and middle-income countries, especially Brazil. PURPOSE: To describe Brazilian studies using follow-up analysis after PA interventions...
March 15, 2018: Journal of Physical Activity & Health
Renata Valle Pedroso, José Maria Cancela, Carlos Ayán, Angelica Miki Stein, Gilson Fuzaro, José Luiz Riani Costa, Francisco J Fraga, Ruth Ferreira Santos-Galduróz
BACKGROUND: Evidence regarding the benefits of physical activity on the mental processing information of patients with Alzheimer's disease assessed objectively is scarce and can be observed through event-related potentials, such as the P300. The aim of the study was to identify the effects of physical exercises on mental processing information in the elderly with Alzheimer's disease through neurophysiological measures (P300 amplitude and latency) and reaction time. METHODS: A total of 31 patients with Alzheimer's disease participated in this study: 14 in functional exercise (FE) group and 17 in social gathering (SG) group who carried out three 1-hour sessions per week of FE and SG activities, respectively, for a 12-week period...
March 15, 2018: Journal of Physical Activity & Health
Francesca Maria Notarangelo, Giuseppe Maglietta, Paola Bevilacqua, Marco Cereda, Piera Angelica Merlini, Giovanni Quinto Villani, Paolo Moruzzi, Giampiero Patrizi, Guidantonio Malagoli Tagliazucchi, Antonio Crocamo, Angela Guidorossi, Filippo Pigazzani, Elisa Nicosia, Giorgia Paoli, Marco Bianchessi, Mario Angelo Comelli, Caterina Caminiti, Diego Ardissino
BACKGROUND: Clopidogrel is still frequently used in patients with acute coronary syndromes (ACS), but its efficacy is hampered by interpatient response variability, due to genetic polymorphisms associated with clopidogrel metabolism. OBJECTIVE: To evaluate whether selecting antiplatelet therapy (clopidogrel, prasugrel or ticagrelor) on the basis of a patient's genetic and clinical characteristics leads to better clinical outcomes in comparison with the standard of care, which bases the selection on clinical characteristics alone METHODS: Patients hospitalised for ACS were randomly assigned to standard of care or pharmacogenomic arm, which included the genotyping of ABCB1, CYP2C19*2, CYP2C19*17 using an ST Q3 system that provide the data within 70 minutes at each patient's bedside...
February 24, 2018: Journal of the American College of Cardiology
Melissa H Bellin, Angelica Newsome, Cassie Lewis-Land, Joan Kub, Shawna S Mudd, Rachel Margolis, Arlene M Butz
INTRODUCTION: Low-income caregiver perspectives on asthma management are understudied but may illuminate strategies to improve care delivery and child outcomes. METHOD: Purposive sampling methods were used to recruit 15 caregivers of children with frequent asthma emergency department visits. Interviews explored how poverty and stress affect asthma management. Grounded theory coding techniques were used to analyze the data. RESULTS: Participants were the biological mother (100%) and were poor (75% had mean annual income ≤ $30,000)...
March 12, 2018: Journal of Pediatric Health Care
Filomena E C de Alencar, Rosely Dos Santos Malafronte, Crispim Cerutti Junior, Lícia Natal Fernandes, Julyana Cerqueira Buery, Blima Fux, Helder Ricas Rezende, Ana Maria Ribeiro de Castro Duarte, Antonio Ralph Medeiros-Sousa, Angelica Espinosa Miranda
BACKGROUND: The hypotheses put forward to explain the malaria transmission cycle in extra-Amazonian Brazil, an area of very low malaria incidence, are based on either a zoonotic scenario involving simian malaria, or a scenario in which asymptomatic carriers play an important role. OBJECTIVES: To determine the incidence of asymptomatic infection by detecting Plasmodium spp. DNA and its role in residual malaria transmission in a non-Amazonian region of Brazil. METHODS: Upon the report of the first malaria case in 2010 in the Atlantic Forest region of the state of Espírito Santo, inhabitants within a 2 km radius were invited to participate in a follow-up study...
March 14, 2018: Malaria Journal
Wanderlei Abadio de Oliveira, Jorge Luiz da Silva, Iara Falleiros Braga, Claudio Romualdo, Simona Carla Silvia Caravita, Marta Angélica Iossi Silva
This study unveils the meaning attributed by students to bullying and contributes to the approach of student health. The objective was to identify the dimensions of the conceptions of students regarding bullying. A total of 55 students from 11 public schools participated by answering semi-structured interviews. Dimensional analysis was used to treat data and a matrix was constructed with the dimensions identified. The Grounded Theory was adopted as the methodological and theoretical framework. The adolescents were aware of the main dimensions of bullying but explained it descriptively and from individual perspectives...
March 2018: Ciência & Saúde Coletiva
Rodrigo Dalke Meucci, Angélica Ozório Linhares, Daniel Wenceslau Votto Olmedo, Ewerton Luiz Porto Cousin Sobrinho, Vlanice Madruga Duarte, Juraci Almeida Cesar
The scope of this article is to assess low back pain prevalence and associated factors in the last 12 months among adolescents in a city in the south of the State of Piauí. It was a cross-sectional study which included 1,112 adolescents aged 13-19 in the city of Caracol, Piauí. Demographic, socio-economic, nutritional, behavioral and comorbidty characteristics were investigated. The outcome was the occurrence of low back pain (LBP) in the last 12 months. The outcome prevalence was calculated in accordance with independent variables...
March 2018: Ciência & Saúde Coletiva
Thaís Garcia, Sílvia Aline Dos Santos Andrade, Angélica Teresa Biral, André Luiz Bertani, Laura Miranda de Oliveira Caram, Talita Jacon Cezare, Irma Godoy, Suzana Erico Tanni
OBJECTIVE: To evaluate the effectiveness of a smoking cessation program, delivered by trained health care professionals, in patients hospitalized for acute respiratory disease (RD) or heart disease (HD). METHODS: Of a total of 393 patients evaluated, we included 227 (146 and 81 active smokers hospitalized for HD and RD, respectively). All participants received smoking cessation treatment during hospitalization and were followed in a cognitive-behavioral smoking cessation program for six months after hospital discharge...
January 2018: Jornal Brasileiro de Pneumologia: Publicaça̋o Oficial da Sociedade Brasileira de Pneumologia e Tisilogia
Martín Bedolla-Barajas, Norma Angélica Pulido-Guillén, Bolívar Vivar-Aburto, Jaime Morales-Romero, José Raúl Ortiz-Peregrina, Martín Robles-Figueroa
OBJECTIVE: To investigate whether there is an association between suicidal ideation (SI) and allergic diseases in adults. METHODS: This was a comparative cross-sectional study involving individuals ranging from 20 to 50 years of age recruited from a university hospital in the city of Guadalajara, Mexico. We included patients with a confirmed diagnosis of allergic asthma, those with a confirmed diagnosis of allergic rhinitis, and healthy controls. All subjects completed the Beck Depression Inventory-II (BDI-II), which includes an item that evaluates the presence of suicidal thoughts or desires within the last two weeks, in order to identify SI...
January 2018: Jornal Brasileiro de Pneumologia: Publicaça̋o Oficial da Sociedade Brasileira de Pneumologia e Tisilogia
Liliana Angelica Ponguta, Muneera Abdul Rasheed, Chin Regina Reyes, Aisha Khizar Yousafzai
The international community has set forth global targets that include calls for universal access to high-quality early childhood care and education (ECCE), as indicated in the United Nations' Sustainable Development Goals. One major impediment to achieving this target is the lack of a skilled workforce. In this paper, we argue the case for leveraging youth as an untapped resource for supplying the workforce the ECCE system needs. Youth comprise a large proportion of the global population, and historically, although youth experience higher unemployment rates than their adult counterparts, youth are important agents of social awareness, social transformation, and community mobilization in multiple global contexts...
March 2018: New Directions for Child and Adolescent Development
Eduardo Paulino, Andréia Cristina de Melo, Angélica Nogueira-Rodrigues, Luiz Claudio Santos Thuler
No abstract text is available yet for this article.
March 1, 2018: Journal of Gynecologic Oncology
Angelica V Glover, Diane C Berry, Todd A Schwartz, Alison M Stuebe
OBJECTIVE:  To evaluate the relationship between prenatal metabolic markers and breastfeeding outcomes in women with gestational diabetes mellitus (GDM). STUDY DESIGN:  Secondary analysis of a cluster-randomized trial of a lifestyle intervention to improve metabolic health among women with GDM. Women were enrolled between 22 and 36 weeks' gestation and followed through 10 months postpartum. Metabolic markers were measured at enrollment. Women reported when they stopped breastfeeding, whether they breastfed as long as desired, and when they introduced formula...
February 2, 2018: American Journal of Perinatology
Edson Baltazar Estrada-Arriaga, Jesús Hernández-Romano, Liliana García-Sánchez, Rosa Angélica Guillén Garcés, Erick Obed Bahena-Bahena, Oscar Guadarrama-Pérez, Gabriela Eleonora Moeller Chavez
In this study, a continuous flow stack consisting of 40 individual air-cathode MFC units was used to determine the performance of stacked MFC during domestic wastewater treatment operated with unconnected individual MFC and in series and parallel configuration. The voltages obtained from individual MFC units were of 0.08-1.1 V at open circuit voltage, while in series connection, the maximum power and current density were 2500 mW/m2 and 500 mA/m2 (4.9 V), respectively. In parallel connection, the maximum power and current density was 5...
March 9, 2018: Journal of Environmental Management
Katherine H Karlsgodt, Angelica A Bato, Toshikazu Ikuta, Bart D Peters, Pamela DeRosse, Philip R Szeszko, Anil K Malhotra
BACKGROUND: Externalizing behaviors are negative behaviors expressed outwardly, including rule breaking, aggression, and risk taking; internalizing behaviors are expressed inwardly, including depression, withdrawal, and anxiety. Such behavior can cause problems in early life and predict difficulties across the lifespan. There is evidence for a relationship between executive function and both externalizing and internalizing. However, although these behaviors occur along a spectrum, there is little neuroimaging research on this relationship in typically developing youth...
February 2018: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
Suzanne Phelan, Rena R Wing, Anna Brannen, Angelica McHugh, Todd A Hagobian, Andrew Schaffner, Elissa Jelalian, Chantelle N Hart, Theresa O Scholl, Karen Munoz-Christian, Elaine Yin, Maureen G Phipps, Sarah Keadle, Barbara Abrams
Background: Behavioral lifestyle interventions during pregnancy can prevent excessive gestational weight gain (GWG) in women with normal weight; however, effective interventions to reduce GWG in ethnically diverse women with obesity are lacking. Objective: A randomized controlled trial was conducted to test whether a behavioral lifestyle intervention with partial meal replacement reduces GWG rate in Hispanic and non-Hispanic women with overweight or obesity relative to enhanced usual care...
February 1, 2018: American Journal of Clinical Nutrition
Angelica Geter, Madeline Y Sutton, Carl Armon, Marcus D Durham, Frank J Palella, Ellen Tedaldi, Rachel Hart, Kate Buchacz
[This corrects the article DOI: 10.1371/journal.pone.0189973.].
2018: PloS One
Garzón-Zúñiga Marco Antonio, Alvillo-Rivera Angélica Julieta, Ramírez Camperos Esperanza, Buelna Gerardo, Díaz-Godínez Gerardo, Estrada-Arriaga Edson Baltazar
This study was focused on the application of an aerobic biofiltration (BF) with Ficus benjamina wood chips as support medium, inoculated with two basidiomycete fungi, Phanerochaete chrysosporium (BF 1) and Trametes versicolor (BF 2), to treat Tequila vinasses from a Tequila industry. The biofiltration system was compared with a biofilter system without basidiomycete fungi (BF W), in order to determine the influence of fungi on the treatment of vinasses. Three different vinasses/water ratios (30/70, 40/60, and 50/50) were evaluated...
March 2018: Water Science and Technology: a Journal of the International Association on Water Pollution Research
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