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https://www.readbyqxmd.com/read/29034199/cardioprotective-effects-of-achillea-wilhelmsii-on-the-isolated-rat-heart-in-ischemia-reperfusion
#1
M Mahmoudabady, M Lashkari, S Niazmand, M Soukhtanloo
CONTEXT: There are some reports about protective effects of Achillea on the heart. OBJECTIVE: We investigated the effect of Achillea wilhelmsii extract on cardiac function during ischemia-reperfusion (I/R) injury in the isolated rat heart. MATERIALS AND METHODS: 60 male Wistar rats were randomly divided into 6 groups; 1: Control group, 2: Control-ischemia (CI) 3: vitamin C (10 mg/kg), 4-6: Extract groups (E 100, E 200 and E 400 mg/kg). The animals received normal saline, vitamin C or A...
October 2017: Journal of Traditional and Complementary Medicine
https://www.readbyqxmd.com/read/29031783/antidiabetic-effect-of-achillea-millefollium-through-multitarget-interactions-%C3%AE-glucosidases-inhibition-insulin-sensitization-and-insulin-secretagogue-activities
#2
Fabiola Chávez-Silva, Litzia Cerón-Romero, Luis Arias-Durán, Gabriel Navarrete-Vázquez, Julio Almanza-Pérez, Rubén Román-Ramos, Guillermo Ramírez-Ávila, Irene Perea-Arango, Rafael Villalobos-Molina, Samuel Estrada-Soto
ETHNOPHARMACOLOGICAL IMPORTANCE: Achillea millefolium L. (Asteraceae) is a perennial herb used in Mexican folk medicine for treatment of several pathologies, including inflammatory and spasmodic gastrointestinal disorders, hepatobiliary complaints, overactive cardiovascular, respiratory ailments and diabetes. AIM OF THE STUDY: To evaluate the potential antidiabetic effect in vivo and to establish the potential mode of action through in vitro approaches of Achillea millefolium...
October 12, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29026857/repellency-effect-of-essential-oils-of-some-native-plants-and-synthetic-repellents-against-human-flea-pulex-irritans-siphonaptera-pulicidae
#3
Mohammad Bagher Ghavami, Fahimeh Poorrastgoo, Behrooz Taghiloo, Jamshid Mohammadi
BACKGROUND: Fleas are important vectors of human and animal disease, and control measures for protection against their bites and flea-borne diseases are necessary. METHODS: The essential oils (EOs) of four native medicinal plants, Ziziphora tenuiore, Myrtus communis, Achillea wilhelmsii and Mentha piperita were isolated by hydrodistillation technique and analyzed by GC-MC. The repellent activity of EOs and synthetic compounds, DEET and permethrin, were assayed on human subjects against field collected fleas...
March 2017: Journal of Arthropod-borne Diseases
https://www.readbyqxmd.com/read/29023061/protective-role-of-achillea-biebersteinii-pretreatment-on-dimethoate-induced-oxidative-stress-in-guinea-pigs-liver
#4
Yahya Saleh Al-Awthan, Mohamed Ali Al-Duais, Amany Abdulfatah Hazeb, Waleed Ahmed Alril
OBJECTIVE: The present study investigated the influence of Achillea biebersteinii (Ab), a medicinal herb used widely in Yemeni's folk medicine as analgesic, antipyretic, against diarrhea and flatulence and for liver diseases, on the liver antioxidant potential of guinea pigs acutely intoxicated with dimethoate pesticide (DM). MATERIALS AND METHODS: Animals were administered with Ab aqueous extract (50 and 100 mg kg-1 b.wt., orally) or silymarin (100 mg kg-1 b.wt...
2017: Pakistan Journal of Biological Sciences: PJBS
https://www.readbyqxmd.com/read/29021897/patient-outcome-of-emergency-laparotomy-improved-with-increasing-number-of-surgeons-on-call-in-a-university-hospital-audit-loop
#5
Anwar Hussain, Fahad Mahmood, Chui Teng, Sadaf Jafferbhoy, David Luke, Achilleas Tsiamis
AIM: Emergency laparotomy is a commonly performed high-mortality surgical procedure. The National Emergency Laparotomy Network (NELA) published an average mortality rate of 11.1% and a median length of stay equivalent to 16.3 days in patients undergoing emergency laparotomy. This study presents a completed audit loop after implementing the change of increasing the number of on-call surgeons in the general surgery rota of a university hospital. The aim of this study was to evaluate the outcomes of emergency laparotomy in a single UK tertiary centre after addition of one more consultant in the daily on-call rota...
November 2017: Annals of Medicine and Surgery
https://www.readbyqxmd.com/read/29021408/repeat-syphilis-has-a-different-immune-response-compared-with-initial-syphilis-an-analysis-of-biomarker-kinetics-in-two-cohorts
#6
Chris Kenyon, Achilleas Tsoumanis, Kara Osbak, Marjan Van Esbroeck, Eric Florence, Tania Crucitti, Luc Kesten
OBJECTIVE: We aimed to asses if there are differences in the clinical presentation and immune response of repeat as compared with initial syphilis. METHODS: Prospective study: we prospectively recruited all patients with a new diagnosis of syphilis and tested their plasma for a range of cytochemokines and rapid plasma reagin (RPR) at baseline pretreatment and 6 months following therapy. Retrospective study: we compared RPR assay response kinetics between initial and repeat syphilis in persons attending our HIV/STI clinic from 1993 to 2016...
October 11, 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/29020217/long-term-clinical-outcomes-in-visceral-leishmaniasis-hiv-co-infected-patients-during-and-after-pentamidine-secondary-prophylaxis-in-ethiopia-a-single-arm-clinical-trial-authors-and-affiliations
#7
Ermias Diro, Koert Ritmeijer, Marleen Boelaert, Fabiana Alves, Rezika Mohammed, Charles Abongomera, Raffaella Ravinetto, Maaike De Crop, Helina Fikre, Cherinet Adera, Harry van Loen, Achilleas Tsoumanis, Wim Adriaensen, Asrat Hailu, Johan van Griensven
Background: We have conducted a single-arm trial evaluating monthly pentamidine secondary prophylaxis (PSP) to prevent visceral leishmaniasis (VL) relapse in Ethiopian HIV-patients. Outcomes at 12 months of PSP have been previously reported, supporting PSP effectiveness and safety. However, remaining relapse-free after PSP discontinuation is vital. We now report outcomes and associated factors for a period of upto 2.5 years after initiating PSP, including one year follow-up after PSP discontinuation...
September 13, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29020196/the-risk-and-predictors-of-visceral-leishmaniasis-relapse-in-human-immunodeficiency-virus-coinfected-patients-in-ethiopia-a-retrospective-cohort-study
#8
Charles Abongomera, Ermias Diro, Florian Vogt, Achilleas Tsoumanis, Zelalem Mekonnen, Henok Admassu, Robert Colebunders, Rezika Mohammed, Koert Ritmeijer, Johan van Griensven
Background: East Africa, where Leishmania donovani is prevalent, faces the highest burden world-wide of visceral leishmaniasis (VL) and human immunodeficiency virus (HIV) coinfection. However, data on the risk and predictors of VL relapse are scarce. Such information is vital to target medical follow-up and interventions to those at highest risk. Methods: We conducted a retrospective cohort study at a Médecins Sans Frontières-supported health center in northwest Ethiopia...
July 20, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28976884/accumulation-of-heavy-metals-from-soil-in-medicinal-plants
#9
Nina Kočevar Glavač, Svetlana Djogo, Slavica Ražić, Samo Kreft, Marjan Veber
Medicinal plants accumulate heavy metals from contaminated soil, and their consumption can cause poisoning. Our objective was to determine the levels of Pb, Cd, Zn, Cu, Fe, and Mn in four medicinal plant species (Achillea millefolium, Hypericum perforatum, Plantago lanceolata, and Urtica dioica) and their native soil, all sampled at a former smelter. The highest soil Cd, Pb, and Zn levels surpassed the maximum allowed limit 75-fold, 48-fold, and 14-fold, respectively. Their soil levels correlated with those in the plants, but this was not the case with Cu, Fe, and Mn...
September 26, 2017: Arhiv za Higijenu Rada i Toksikologiju
https://www.readbyqxmd.com/read/28974564/corrigendum-a-comparative-analysis-of-whole-genome-sequencing-of-esophageal-adenocarcinoma-pre-and-post-chemotherapy
#10
Ayesha Noorani, Jan Bornschein, Andy G Lynch, Maria Secrier, Achilleas Achilleos, Matthew Eldridge, Lawrence Bower, Jamie M J Weaver, Jason Crawte, Chin-Ann Ong, Nicholas Shannon, Shona MacRae, Nicola Grehan, Barbara Nutzinger, Maria O'Donovan, Richard Hardwick, Simon Tavaré, Rebecca C Fitzgerald
No abstract text is available yet for this article.
October 2017: Genome Research
https://www.readbyqxmd.com/read/28970987/all-arthroscopic-suture-fixation-of-patellar-osteochondritis-dissecans
#11
Johannes Barth, Paul Brossard, Achilleas Boutsiadis, Nicolas Tardy, Jean-Claude Panisset, Romain Seil
Osteochondritis dissecans of the knee, despite its cause, is characterized by the impairment of the subchondral bone. Failure of its spontaneous healing makes surgical fixation often necessary. The patella is less affected than other locations in the knee. Its surgical treatment remains a challenge due to the thickness of the lesion and the complex approach of the retropatellar cartilage. Arthroscopy has the theoretical advantage to avoid a possible arthrotomy; however, the retrograde application of fixation materials does not guarantee good fragment compression and may lead to cartilage penetration and damage...
August 2017: Arthroscopy Techniques
https://www.readbyqxmd.com/read/28970981/adjustable-button-devices-for-all-arthroscopic-posterior-cruciate-ligament-reconstruction-using-the%C3%A2-hamstrings-tendons-and-the-forgotten-transseptal-approach
#12
Paul Brossard, Achilleas Boutsiadis, Jean-Claude Panisset, Frédéric Mauris, Johannes Barth
Posterior cruciate ligament (PCL) ruptures account for nearly 20% of all ligamentous knee injuries. These may be either isolated or in the setting of a more complex knee trauma. Isolated tears with moderate posterior laxity (grades I or II) are commonly treated conservatively; nevertheless, symptomatic grade III injuries frequently require surgical intervention. PCL reconstruction remains a challenging surgery for multiple reasons like the neurovascular structures' proximity, the difficult passage of the graft with the "killer turn" angle, or the risk of poor graft fixation...
August 2017: Arthroscopy Techniques
https://www.readbyqxmd.com/read/28942136/traditional-wound-healing-plants-used-in-the-balkan-region-southeast-europe
#13
REVIEW
Snežana Jarić, Olga Kostić, Zorana Mataruga, Dragana Pavlović, Marija Pavlović, Miroslava Mitrović, Pavle Pavlović
ETHNOPHARMACOLOGICAL RELEVANCE: The geographical and ecological specificity of the Balkan Peninsula has resulted in the development of a distinct diversity of medicinal plants. In the traditional culture of the Balkan peoples, plants have medicinal, economic and anthropological/cultural importance, which is reflected in the sound knowledge of their diversity and use. This study analyses the traditional use of medicinal plants in the treatment of wounds and the pharmacological characteristics of the most frequently used species...
September 21, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28930245/antioxidant-and-antimicrobial-activities-of-the-essential-oil-of-achillea-millefolium-l-grown-in-france
#14
Chaker El-Kalamouni, Petras Rimantas Venskutonis, Bachar Zebib, Othmane Merah, Christine Raynaud, Thierry Talou
Background: This study aimed to examine the composition of essential oil (EO) of A. millefolium aerial parts wild plant grown in France and evaluate its antioxidant, antibacterial, and antifungal activities. Methods: GC-MS was used to identify the chemical composition of EO. Antioxidant activity (AA) of EO was evaluated by Oxipres method. Antimicrobial activity of EO was evaluated by Agar-well diffusion and a broth microdilution assay. Results: Forty-three volatile compounds were identified. Major compounds were camphor (12...
May 19, 2017: Medicines (Basel, Switzerland)
https://www.readbyqxmd.com/read/28923483/synchrony-measure-for-a-neuron-driven-by-excitatory-and-inhibitory-inputs-and-its-adaptation-to-experimentally-recorded-data
#15
Christina Zavou, Antria Kkoushi, Achilleas Koutsou, Chris Christodoulou
The aim of the current work is twofold: firstly to adapt an existing method measuring the input synchrony of a neuron driven only by excitatory inputs in such a way so as to account for inhibitory inputs as well and secondly to further appropriately adapt this measure so as to be correctly utilised on experimentally-recorded data. The existing method uses the normalized pre-spike slope (NPSS) of the membrane potential, resulting from observing the slope of depolarization of the membrane potential of a neuron prior to the moment of crossing the threshold within a short period of time, to identify the response-relevant input synchrony and through it to infer the operational mode of a neuron...
September 15, 2017: Bio Systems
https://www.readbyqxmd.com/read/28877373/prevalence-of-onychomycosis-among-patients-with-nail-psoriasis-who-are-not-receiving-immunosuppressive-agents-results-of-a-pilot-study
#16
Aikaterini Tsentemeidou, Timoleon-Achilleas Vyzantiadis, Aikaterini Kyriakou, Dimitrios Sotiriadis, Aikaterini Patsatsi
Nail psoriasis and onychomycosis can often be hard to differentiate clinically and may coexist, complicating each other's course. The aim of this study was to determine the prevalence of onychomycosis among patients with nail psoriasis not being treated with immunosuppressive agents, which constitute an independent risk factor for fungal infections. A cross-sectional study was performed. All adult patients with nail psoriasis who were not receiving antifungal and/or immunosuppressive treatment were recruited at the 2nd University Dermatology Department of Aristotle University of Thessaloniki from 10/2016 till 02/2017...
September 6, 2017: Mycoses
https://www.readbyqxmd.com/read/28868116/bio-effectiveness-of-the-main-flavonoids-of-achillea-millefolium-in-the-pathophysiology-of-neurodegenerative-disorders-a-review
#17
REVIEW
Fatemeh Ayoobi, Ali Shamsizadeh, Iman Fatemi, Alireza Vakilian, Mohammad Allahtavakoli, Gholamhossein Hassanshahi, Amir Moghadam-Ahmadi
The Achillea millefolium L. (Yarrow) is a common herb which is widely being used, worldwide. Achillea is being used for treatment of many disorders since centuries. It is considered safe for supplemental use and flavonoids such as kaempferol, luteolin and apigenin are of main constituents present in Achillea. Most of both antioxidant and anti-inflammatory properties of this herb have been attributed to its flavonoid content. Oxidative and inflammatory processes play important roles in pathogenesis of neurodegenerative diseases...
June 2017: Iranian Journal of Basic Medical Sciences
https://www.readbyqxmd.com/read/28861681/in-vivo-estimation-of-normal-amygdala-volume-from-structural-mri-scans-with-anatomical-based-segmentation
#18
Achilleas Siozopoulos, Vasilios Thomaidis, Panos Prassopoulos, Aliki Fiska
PURPOSE: Literature includes a number of studies using structural MRI (sMRI) to determine the volume of the amygdala, which is modified in various pathologic conditions. The reported values vary widely mainly because of different anatomical approaches to the complex. This study aims at estimating of the normal amygdala volume from sMRI scans using a recent anatomical definition described in a study based on post-mortem material. METHODS: The amygdala volume has been calculated in 106 healthy subjects, using sMRI and anatomical-based segmentation...
August 31, 2017: Surgical and Radiologic Anatomy: SRA
https://www.readbyqxmd.com/read/28846077/metabolic-cooperation-between-co-cultured-lung-cancer-cells-and-lung-fibroblasts
#19
Michael I Koukourakis, Dimitra Kalamida, Achilleas G Mitrakas, Maria Liousia, Stamatia Pouliliou, Efthimios Sivridis, Alexandra Giatromanolaki
Cooperation of cancer cells with stromal cells, such as cancer-associated fibroblasts (CAFs), has been revealed as a mechanism sustaining cancer cell survival and growth. In the current study, we focus on the metabolic interactions of MRC5 lung fibroblasts with lung cancer cells (A549 and H1299) using co-culture experiments and studying changes of the metabolic protein expression profile and of their growth and migration abilities. Using western blotting, confocal microscopy and RT-PCR, we observed that in co-cultures MRC5 respond by upregulating pyruvate dehydrogenase (PDH) and the monocarboxylate transporter MCT1...
August 28, 2017: Laboratory Investigation; a Journal of Technical Methods and Pathology
https://www.readbyqxmd.com/read/28845317/arterial-thoracic-outlet-syndrome-treated-successfully-with-totally-endoscopic-first-rib-resection
#20
Sofoklis Mitsos, Davide Patrini, Sara Velo, Achilleas Antonopoulos, Martin Hayward, Robert S George, David Lawrence, Nikolaos Panagiotopoulos
Thoracic outlet syndrome (TOS) is a constellation of signs and symptoms caused by compression of the neurovascular structures in the thoracic outlet. TOS may be classified as either neurogenic TOS (NTOS) or vascular TOS: venous TOS (VTOS) or arterial TOS (ATOS), depending on the specific structure being affected. The basis for the surgical treatment of TOS is resection of the first rib, and it may be combined with scalenectomy or cervical rib resection. Herein, we describe a case of arterial thoracic outlet syndrome which was successfully treated with totally endoscopic video-assisted thoracoscopic surgery (VATS) first rib resection...
2017: Case Reports in Pulmonology
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