keyword
MENU ▼
Read by QxMD icon Read
search

aesculus

keyword
https://www.readbyqxmd.com/read/27727329/molecular-mechanism-for-cellular-response-to-%C3%AE-escin-and-its-therapeutic-implications
#1
Dominik Domanski, Oliwia Zegrocka-Stendel, Anna Perzanowska, Malgorzata Dutkiewicz, Magdalena Kowalewska, Iwona Grabowska, Dorota Maciejko, Anna Fogtman, Michal Dadlez, Katarzyna Koziak
β-escin is a mixture of triterpene saponins isolated from the horse chestnut seeds (Aesculus hippocastanum L.). The anti-edematous, anti-inflammatory and venotonic properties of β-escin have been the most extensively clinically investigated effects of this plant-based drug and randomized controlled trials have proved the efficacy of β-escin for the treatment of chronic venous insufficiency. However, despite the clinical recognition of the drug its pharmacological mechanism of action still remains largely elusive...
2016: PloS One
https://www.readbyqxmd.com/read/27699277/potential-tree-species-for-use-in-urban-areas-in-temperate-and-oceanic-climates
#2
Miklas Scholz, Vincent C Uzomah, Furat A M Al-Faraj
This study aims to assess the potential of trees for integration in urban development by evaluating the damage caused by trees in relation to various tree characteristics. Tree damage to permeable pavement systems and other urban structures such as impermeable pavements, kerbs, roads, retaining walls, footpaths, walls and buildings were assessed to identify the most suitable trees for the urban environment. One hundred square sites of 100 m × 100 m were randomly selected in Greater Manchester for this representative example case study to demonstrate the assessment methodology...
September 2016: Heliyon
https://www.readbyqxmd.com/read/27515267/efficacy-test-of-horse-chestnut-leaf-extract-alh-l1005-as-matrix-metalloproteinase-inhibitors-in-ligature-induced-periodontitis-in-canine-model
#3
Se Eun Kim, Tae Hyun Kim, Shin Ae Park, Won Tae Kim, Young Woo Park, Jae Sang Ahn, Manbok Jeong, Min-Young Kim, Kangmoon Seo
Matrix metalloproteinases (MMPs) are the main proteinase associated with periodontal tissue destruction and remodeling. Therefore, inhibition of the host-derived MMPs is accounted to play a key role in the prevention and reduction of the periodontitis progression. Horse chestnut (Aesculus hippocastanum L.) extracts had been used as a remedy for inflammatory disease, traditionally. This study was performed to assess the clinical effect of ALH-L1005 on the periodontitis as MMPs inhibitor. ALH-L1005 was obtained from horse chestnut leaf and the MMPs inhibitory activities were estimated...
August 10, 2016: Journal of Veterinary Science
https://www.readbyqxmd.com/read/27459035/bioaccumulation-of-metals-in-the-trees-of-novi-sad-serbia
#4
Snežana Štrbac, Marjana Gavrilović, Ljiljana Budakov
In urban and industrial areas, higher plants are used as biomonitors of exposure. The objective of this study was to assess metals accumulation in leaves of dendroflora for the city of Novi Sad, Serbia, in May and September. The investigation was conducted at three sites in the urban area of Novi Sad. Determination of metals concentration for Al, As, Cr, Mn, Fe, Co, Ni, Cu, Zn, Cd, and Pb in the sample was performed by inductively coupled plasma-optical emission spectrometry (ICP/OES). In the leaves of the examined tree species the highest concentrations were obtained for: Al, Fe, Mn, and Zn...
2016: Journal of Toxicology and Environmental Health. Part A
https://www.readbyqxmd.com/read/27424320/the-efficacy-of-aesculus-hippocastanum-seeds-on-diabetic-nephropathy-in-a-streptozotocin-induced-diabetic-rat-model
#5
Onur Elmas, Oytun Erbas, Gurkan Yigitturk
Cytokines, such as transforming growth factor (TGF)-ß1, and increased oxidative stress are considered to be responsible for the development of diabetic nephropathy. We hypothesized that Aesculus hippocastanum (AH) seeds may have preventive effects on oxidative stress and TGF-β-related diabetic nephropathy in streptozotocin (STZ)-induced diabetic nephropathy in rats. Twenty-one male Sprague-Dawley albino rats were divided into three groups (n=7). Except for the control group, they all had diabetic nephropathy induced by an intraperitoneal injection of STZ...
July 14, 2016: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/27268715/testing-the-monophyly-of-aesculus-l-and-billia-peyr-woody-genera-of-tribe-hippocastaneae-of-the-sapindaceae
#6
A J Harris, Chengxin Fu, Qiu-Yun Jenny Xiang, LaRinda Holland, Jun Wen
Hippocastaneae is a well-supported clade in Sapindaceae that comprises 15+ species; 12+ in Aesculus, two in Billia, and one in Handeliodendron Rehder. The monophyly of Aesculus and Billia were widely assumed, but a recent molecular phylogenetic study of Sapindanceae used seven species of Aesculus and one each of Billia and Handeliodendron and showed that Billia and Handeliodendron were nested within Aesculus. Here, we tested the hypothesis that Aesculus and Billia are mutually monophyletic using phylogenetic analyses of seven molecular markers and 31 accessions of Hippocastaneae representing 14 species...
September 2016: Molecular Phylogenetics and Evolution
https://www.readbyqxmd.com/read/27259638/physiological-aspects-of-seed-recalcitrance-a-case-study-on-the-tree-aesculus-hippocastanum
#7
REVIEW
Natalie Obroucheva, Irina Sinkevich, Snejana Lityagina
Recalcitrant seeds are typical of some tropical and subtropical trees. Their post-shedding life activity proceeds in humid air and wet litter. They are desiccation sensitive and, for this reason, have a short life span and need some special procedures for cryopreservation. This review is devoted to the post-shedding life strategy of recalcitrant seeds, which includes the maintenance of high hydration status, metabolic readiness and ability to rapidly germinate before desiccation-induced damage exerts a lethal effect...
September 2016: Tree Physiology
https://www.readbyqxmd.com/read/27241229/host-preference-and-host-colonization-of-the-asian-long-horned-beetle-anoplophora-glabripennis-coleoptera-cerambycidae-in-southern-europe
#8
M Faccoli, R Favaro
The Asian long-horned beetle (ALB), Anoplophora glabripennis (Motschulsky), is a highly polyphagous invasive pest with a broad range of host species, but showing relevant differences between infestation areas. Host preference and host colonization (female fecundity, egg and larval survival) were assessed in a population in Northern Italy by choice and no-choice experiments conducted in both field and laboratory conditions. During 5 years of field observations, ALB was found to infest seven genera of trees: Acer, Aesculus, Betula, Populus, Prunus, Salix and Ulmus...
June 2016: Bulletin of Entomological Research
https://www.readbyqxmd.com/read/27141926/acute-effusive-pericarditis-due-to-horse-chestnut-consumption
#9
Efe Edem, Behlül Kahyaoğlu, Mehmet Akif Çakar
BACKGROUND: There are many well-known causes of pericardial effusion, such as cancer metastasis, bacterial or viral pericarditis, and uremic pericarditis; however, no reports exist in the literature demonstrating a pericardial effusion that led to cardiac tamponade following consumption of an herbal remedy. CASE REPORT: A 32-year-old male patient was referred to our cardiology outpatient clinic with a complaint of dyspnea. The patient's medical history was unremarkable; however, he had consumed 3 boxes of horse chestnut (Aesculus hippocastanum L) paste over the previous 1...
2016: American Journal of Case Reports
https://www.readbyqxmd.com/read/27008697/escin-ia-suppresses-the-metastasis-of-triple-negative-breast-cancer-by-inhibiting-epithelial-mesenchymal-transition-via-down-regulating-loxl2-expression
#10
Yuhui Wang, Xiaotian Xu, Peng Zhao, Bei Tong, Zhifeng Wei, Yue Dai
The saponin fraction of Aesculus chinensis Bunge fruits (SFAC) could inhibit the invasion and migration of MDA-MB-231 cells. Among which, escin Ia showed more potent inhibition of the invasion than other five main saponin constituents. It selectively reduced the expression of LOXL2 mRNA and promoted the expression of E-cadherin mRNA, and prevented the EMT process of MDA-MB-231 cells and TNF-α/TGF-β-stimulated MCF-7 cells. Moreover, it reduced the LOXL2 level in MDA-MB-231 cells but not in MCF-7 cells. When MCF-7 cells were stimulated with TNF-α/TGF-β, transfected with LOXL2 or treated with hypoxia, escin Ia down-regulated the level of LOXL2 in MCF-7 cells...
April 26, 2016: Oncotarget
https://www.readbyqxmd.com/read/26819933/determination-of-four-major-saponins-in-skin-and-endosperm-of-seeds-of-horse-chestnut-aesculus-hippocastanum-l-using-high-performance-liquid-chromatography-with-positive-confirmation-by-thin-layer-chromatography
#11
Zead Helmi Mahmoud Abudayeh, Khaldun Mohammad Al Azzam, Ahmad Naddaf, Uliana Vladimirovna Karpiuk, Viktoria Sergeevna Kislichenko
PURPOSE: To separate and quantify four major saponins in the extracts of the skin and the endosperm of seeds of horse chestnut (Aesculus hippocastanum L.) using ultrasonic solvent extraction followed by a high performance liquid chromatography-diode array detector (HPLC-DAD) with positive confirmation by thin layer chromatography (TLC). METHODS: The saponins: escin Ia, escin Ib, isoescin Ia and isoescin Ib were extracted using ultrasonic extraction method. The optimized extraction conditions were: 70% methanol as extraction solvent, 80 °C as extraction temperature, and the extraction time was achieved in 4 hours...
November 2015: Advanced Pharmaceutical Bulletin
https://www.readbyqxmd.com/read/26819849/the-role-of-geography-and-host-abundance-in-the-distribution-of-parasitoids-of-an-alien-pest
#12
Petra Nováková, Jaroslav Holuša, Jakub Horák
Chalcid wasps (Hymenoptera: Chalcidoidea) are probably the most effective and abundant parasitoids of the horse chestnut leaf miner (Cameraria ohridella), an alien pest in Europe that lacks specialized enemies. We studied how the species richness and abundance of chalcids are influenced by altitude, direction of an alien spread and host abundance of C. ohridella. We quantified the numbers and species richness of chalcid wasps and the numbers of C. ohridella that emerged from horse chestnut (Aesculus hippocastanum) leaf litter samples collected from 35 sites in the Czech Republic...
2016: PeerJ
https://www.readbyqxmd.com/read/26748000/chemometrics-in-biomonitoring-distribution-and-correlation-of-trace-elements-in-tree-leaves
#13
Isidora Deljanin, Davor Antanasijević, Anđelika Bjelajac, Mira Aničić Urošević, Miroslav Nikolić, Aleksandra Perić-Grujić, Mirjana Ristić
The concentrations of 15 elements were measured in the leaf samples of Aesculus hippocastanum, Tilia spp., Betula pendula and Acer platanoides collected in May and September of 2014 from four different locations in Belgrade, Serbia. The objective was to assess the chemical characterization of leaf surface and in-wax fractions, as well as the leaf tissue element content, by analyzing untreated, washed with water and washed with chloroform leaf samples, respectively. The combined approach of self-organizing networks (SON) and Preference Ranking Organization Method for Enrichment Evaluation (PROMETHEE) aided by Geometrical Analysis for Interactive Aid (GAIA) was used in the interpretation of multiple element loads on/in the tree leaves...
March 1, 2016: Science of the Total Environment
https://www.readbyqxmd.com/read/26640536/assessment-of-the-potential-health-benefits-of-certain-total-extracts-from-vitis-vinifera-aesculus-hyppocastanum-and-curcuma-longa
#14
Denisa Margină, Octavian Tudorel Olaru, Mihaela Ilie, Daniela Grădinaru, Claudia GuȚu, Sorina Voicu, Anca Dinischiotu, Demetrios A Spandidos, Aristidis M Tsatsakis
A number of recent studies have illustrated the active role of food/natural components in the prevention of chronic diseases and in the improvement of the quality of life. In the present study, we aimed to obtain and characterize certain extracts from Vitis vinifera L., Aesculus hippocastanum L. and Curcuma longa L., focusing on their antioxidant effects in vitro. Three vegetal extracts were obtained for each plant: in water, 50% water-alcohol and in 96% ethanol. These extracts were then analyzed for their qualitative composition by high performance thin layer chromatography (HPTLC) and total phenolic content by ultraviolet-visible spectrophotometry (UV-VIS)...
November 2015: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/26619878/somatic-embryogenesis-in-horse-chestnut-aesculus-hippocastanum-l
#15
Maurizio Capuana
Embryogenic cultures of horse chestnut (Aesculus hippocastanum L.) can be obtained from different organs and tissues. We describe here the induction from stamen filaments and the procedures applied for the successive phases of somatic embryo development and maturation. Embryogenic tissues are obtained on Murashige and Skoog medium containing 9.0 μM 2,4-dichlorophenoxyacetic acid. Somatic embryos develop after transfer to hormone-free medium enriched with glutamine. Maturation and germination of isolated embryos are achieved by transfer to medium containing polyethylene glycol 4000 and activated charcoal, successive desiccation treatment, and cold storage at 4 °C for 8 weeks...
2016: Methods in Molecular Biology
https://www.readbyqxmd.com/read/26581609/natural-biosorbents-garlic-stem-and-horse-chesnut-shell-for-removal-of-chromium-vi-from-aqueous-solutions
#16
Şerife Parlayıcı, Erol Pehlivan
The biosorption of Cr(VI) by the garlic stem (GS)-Allium sativum L. and horse chesnut shell (HCS)-Aesculus hippocastanum plant residues in a batch type reactor was studied in detail for the purpose of wastewater treatment. The influence of initial Cr(VI) concentration, time, and pH was investigated to optimize Cr(VI) removal from aqueous solutions and equilibrium isotherms and kinetic data. This influence was evaluated. The adsorption capacity of the GS and the HCS for Cr(VI) was determined with the Langmuir and Freundlich isotherm models, and the data was fitted to the Langmuir...
December 2015: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/26391063/esculin-exhibited-anti-inflammatory-activities-in-vivo-and-regulated-tnf-%C3%AE-and-il-6-production-in-lps-stimulated-mouse-peritoneal-macrophages-in-vitro-through-mapk-pathway
#17
Xiaofeng Niu, Yu Wang, Weifeng Li, Hailin Zhang, Xiumei Wang, Qingli Mu, Zehong He, Huan Yao
Esculin, a coumarinic derivative found in Aesculus hippocastanum L. (Horse-chestnut), has been reported to have potent anti-inflammatory properties. The present study is designed to investigate the protective effects of esculin on various inflammation models in vivo and in vitro and to clarify the possible mechanism. Induced-animal models of inflammation and lipopolysaccharide (LPS)-challenged mouse peritoneal macrophages were used to examine the anti-inflammatory activity of esculin. In present study, xylene-induced mouse ear edema, carrageenan-induced rat paw edema, and carrageenan-induced mouse pleurisy were attenuated by esculin...
December 2015: International Immunopharmacology
https://www.readbyqxmd.com/read/26376212/rutosides-for-treatment-of-post-thrombotic-syndrome
#18
REVIEW
Joanne R Morling, Su Ern Yeoh, Dinanda N Kolbach
BACKGROUND: Post-thrombotic syndrome (PTS) is a long-term complication of deep venous thrombosis (DVT) that is characterised by pain, swelling, and skin changes in the affected limb. One in three patients with DVT will develop post-thrombotic sequelae within five years. Rutosides are a group of compounds derived from horse chestnut (Aesculus hippocastanum), a traditional herbal remedy for treating oedema formation in chronic venous insufficiency (CVI). However, it is not known whether rutosides are effective and safe in the treatment of PTS...
September 16, 2015: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/26373375/rutosides-for-prevention-of-post-thrombotic-syndrome
#19
REVIEW
Joanne R Morling, Su Ern Yeoh, Dinanda N Kolbach
BACKGROUND: Post-thrombotic syndrome (PTS) is a long-term complication of deep venous thrombosis (DVT) that is characterised by pain, swelling, and skin changes in the affected limb. One in three patients with DVT will develop post-thrombotic sequelae within five years. The current standard care for the prevention of PTS following DVT is elastic compression stockings. Rutosides are a group of compounds derived from horse chestnut (Aesculus hippocastanum), a traditional herbal remedy for treating oedema formation in chronic venous insufficiency (CVI)...
September 16, 2015: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/26353966/the-novel-approach-to-the-biomonitor-survey-using-one-and-two-dimensional-kohonen-networks
#20
Isidora Deljanin, Davor Antanasijević, Mira Aničić Urošević, Milica Tomašević, Aleksandra Perić-Grujić, Mirjana Ristić
To compare the applicability of the leaves of horse chestnut (Aesculus hippocastanum) and linden (Tilia spp.) as biomonitors of trace element concentrations, a coupled approach of one- and two-dimensional Kohonen networks was applied for the first time. The self-organizing networks (SONs) and the self-organizing maps (SOMs) were applied on the database obtained for the element accumulation (Cr, Fe, Ni, Cu, Zn, Pb, V, As, Cd) and the SOM for the Pb isotopes in the leaves for a multiyear period (2002-2006). A...
October 2015: Environmental Monitoring and Assessment
keyword
keyword
95179
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"