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https://www.readbyqxmd.com/read/28423952/advances-in-the-research-of-celery-an-important-apiaceae-vegetable-crop
#1
Meng-Yao Li, Xi-Lin Hou, Feng Wang, Guo-Fei Tan, Zhi-Sheng Xu, Ai-Sheng Xiong
Celery (Apium graveolens L.), one of the most important vegetables in Apiaceae family, is cultivated worldwide and utilized in food and cosmetic industries because it is an excellent source of vitamins, phenolic compounds, volatile oils and other nutrients. Celery extracts possess various medicinal properties, such as antibacterial, anti-inflammatory and lowering blood glucose and serum lipid levels. With the rapid advancements in molecular biology and sequencing technology, studies on celery have been performed...
April 20, 2017: Critical Reviews in Biotechnology
https://www.readbyqxmd.com/read/28375121/antioxidant-activity-and-nutritional-assessment-of-under-utilized-medicinal-plants
#2
Anwar Ali Shad, Jehan Bakht, Hamid Ullah Shah, Yosuaf Hayat
The present study investigates the nutritive and anti-nutritive composition of six species (Allium porrum, Amaranthus spinosis, Apium graveolens, Caralluma edulis, Chenopodium album, Urtica dioica). The studied species contained considerable amount of crude protein (4.53-11.41%), crude fat (1.25-3.74%), vitamin C (7.85-28.09mg 100(-1) g) and β-Carotene (18.29-169.33mg 100(-1)g). The mineral profile of Chenopodium album is considered as potential source of Zn (14.51±1.14mg 100-1g), Mn (67.71±0.85mg 100(-1)g), Se (8...
November 2016: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28216960/pharmacological-evaluation-of-apium-leptophyllum-pers-on-bronchial-asthma
#3
Himanshu Bhusan Sahoo, Rakesh Sagar, Ganesh Patro, Madhulita Panda, Saroj Kumar Sahoo, D Priyadarshini
OBJECTIVE: The present study was to investigate the antiasthmatic potential from the flavonoid fraction of Apium leptophyllum fruit (FFALF) to validate its traditional claim. MATERIALS AND METHODS: The antiasthmatic activity of FFALF was evaluated by histamine or acetylcholine-induced bronchospasm model in guinea pigs, compound 48/80 induced mast cell degranulation in albino rats and histamine-induced tracheal contraction in guinea pig. The preconvulsion dyspnea time at 0(th) and 7(th) day at the dose of 100 and 200 mg/kg in guinea pig's bronchospasm model, the percentage of granulated and degranulated mast cell at the dose of 500, 750, and 1000 μg/ml in rats and tracheal contraction at the dose of 500, 750, and 1000 μg/ml in guinea pig were measured and compared with respective control groups...
October 2016: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/28205135/apium-graveolens-extract-influences-mood-and-cognition-in-healthy-mice
#4
Phetcharat Boonruamkaew, Wanida Sukketsiri, Pharkphoom Panichayupakaranant, Wijittra Kaewnam, Supita Tanasawet, Varomyalin Tipmanee, Pilaiwanwadee Hutamekalin, Pennapa Chonpathompikunlert
Apium graveolens is a food flavoring which possesses various health promoting effects. This study investigates the effect of a sub-acute administration of A. graveolens on cognition and anti-depression behaviors via antioxidant and related neurotransmitter systems in mice brains. Cognition and depression was assessed by various models of behavior. The antioxidant system of glutathione peroxidase (GPx), % inhibition of superoxide anion (O2(-)), and lipid peroxidation were studied. In addition, neurochemical parameters including acetylcholinesterase (AChE) and monoamine oxidase-type A (MAO-A) were also evaluated...
February 15, 2017: Journal of Natural Medicines
https://www.readbyqxmd.com/read/28160759/five-herbs-plus-thiamine-reduce-pain-and-improve-functional-mobility-in-patients-with-pain-a-pilot-study
#5
Robert Hedaya
Context • Five herbs-Urtica dioica (stinging nettle), Boswellia serrata, Equisetum arvense, Allium sativum, and Apium graveolens-have been demonstrated to have activity at several anti-inflammatory pathways and have analgesic properties that are effective in treating chronic musculoskeletal pain. Objectives • The study intended to evaluate the clinical efficacy of a proprietary blend of U dioica, B serrata, E arvense, A sativum, A graveolens, and thiamine (vitamin B1), or "the blend," in the treatment of chronic musculoskeletal pain...
January 2017: Alternative Therapies in Health and Medicine
https://www.readbyqxmd.com/read/28160212/phthalides-distribution-in-nature-chemical-reactivity-synthesis-and-biological-activity
#6
Alejandra León, Mayela Del-Ángel, José Luis Ávila, Guillermo Delgado
Phthalides are a relatively small group of natural compounds confined to several plant families and some genera of fungi and liverworts. They are divided into two structural groups, the monomeric and dimeric phthalides, and known mainly as bioactive constituents of different plant species used traditionally for medicinal purposes in Asia, Europe, and North America.The first reports on the chemistry of phthalides appeared at the end of the nineteenth century, in which they were identified as the odor constituents of the essential oil of celery (Apium graveolens) by Ciamician and Silber (1897)...
2017: Progress in the Chemistry of Organic Natural Products
https://www.readbyqxmd.com/read/28101244/celery-extract-inhibits-mouse-cyp2a5-and-human-cyp2a6-activities-via-different-mechanisms
#7
Xiao Deng, Qianghong Pu, Erhao Wang, Chao Yu
Human cytochrome P450 (CYP) 2A6 participates in the metabolism of nicotine and precarcinogens, thus the deliberate inhibition of CYP2A6 may reduce cigarette consumption and therefore reduce the risk of developing the types of cancer associated with smoking. The inhibitory effects and mechanisms of celery (Apium graveolens) extract on mouse CYP2A5 and human CYP2A6 activity remain unclear. These effects were investigated in mouse and human liver microsomes using coumarin 7-hydroxylation in a probe reaction. Celery extract reduced CYP2A5 and CYP2A6 activities in vitro in a dose-dependent manner...
December 2016: Oncology Letters
https://www.readbyqxmd.com/read/28043416/antidiarrhoeal-investigation-of-apium-leptophyllum-pers-by-modulation-of-na-k-atpase-nitrous-oxide-and-intestinal-transit-in-rats
#8
Himanshu Bhusan Sahoo, Rakesh Sagar, Anjan Kumar, Amrita Bhaiji, Subrat Kumar Bhattamishra
BACKGROUND: Apium leptophyllum (Pers.) is an annual herb with traditional appreciation for various pharmacological properties; however, the scientific information on this herb is insufficient. The aim of the present investigation was undertaken to evaluate flavonoidal fraction of A. leptophyllum fruit (FFALF) against diarrhoea on albino rats. METHODS: The antidiarrhoeal study was conducted by castor oil induce diarrhoea, prostaglandin E2 (PGE2) induced enteropooling and intestinal transit by charcoal meal test...
December 2016: Biomedical Journal
https://www.readbyqxmd.com/read/27982754/apium-graveolens-extract-inhibits-cell-proliferation-and-expression-of-vascular-endothelial-growth-factor-and-induces-apoptosis-in-the-human-prostatic-carcinoma-cell-line-lncap
#9
Tülay Köken, Buğra Koca, Mete Özkurt, Nilüfer Erkasap, Gökhan Kuş, Mustafa Karalar
Apium graveolens has been shown to inhibit the growth of a variety of cancer tissues. In this study, we investigated the anticancer effect of A. graveolens on the human prostatic carcinoma cell line LNCaP. LNCaP cells were treated with increasing concentrations of an ethanolic extract of A. graveolens ranging from 1000 to 3000 μg/mL, and viability was determined after 24 and 48 h using the XTT cell proliferation assay. The levels of cleaved poly (ADP-ribose) polymerase (PARP), one of the best biomarkers of apoptosis, were analyzed...
December 2016: Journal of Medicinal Food
https://www.readbyqxmd.com/read/27976117/antiadhesive-and-cytoprotective-effects-of-hydroalcoholic-extract-of-apium-graveolens-seeds-against-uropathogenic-e-coli
#10
S Sarshar, M R Asadi Karam, M Habibi, S Bouzari, X Qin, F M Goycoolea, A Hensel
No abstract text is available yet for this article.
December 2016: Planta Medica
https://www.readbyqxmd.com/read/27862988/isolation-purification-and-identification-of-the-main-phenolic-compounds-from-leaves-of-celery-apium-graveolens-l-var-dulce-mill-pers
#11
Guoyan Liu, Linwu Zhuang, Dandan Song, Chunliang Lu, Xin Xu
We developed a simple and meaningful preparative method for the separation and purification of the main phenolic compounds from the leaves of celery (Apium graveolens L. var. dulce Mill./Pers.) and we established an accurate and specific analytical method for the identification of the main phenolic compounds from celery leaves. The crude extract from celery leaves was prefractioned by polyamide resin to enrich the phenolic compounds. They were then purified further by preparative high-performance liquid chromatography, and seven main phenolic compounds were obtained: including chlorogenic acid, luteolin 7-O-β-d-apiofuranosyl(1→2)-β-d-glucopyranoside, luteolin 7-O-β-d-glucopyranoside, apiin, chrysoeriol 7-O-β-d-apiofuranosyl(1→2)-β-d-glucopyranoside, luteolin 7-O-[β-d-apiofuranosyl(1→2)-(6''-O-malonyl)]-β-d-glucopyranoside, and apigenin 7-O-[β-d-apiofuranosyl(1→2)-(6''-O-malonyl)]-β-d-glucopyranoside...
November 8, 2016: Journal of Separation Science
https://www.readbyqxmd.com/read/27810764/levels-of-heavy-metals-in-wetland-and-marine-vascular-plants-and-their-biomonitoring-potential-a-comparative-assessment
#12
Giuseppe Bonanno, Joseph A Borg, Vincenzo Di Martino
The present study investigated the levels of As, Cd, Cr, Cu, Hg, Mn, Ni, Pb and Zn in the seagrasses Posidonia oceanica and Cymodocea nodosa, and in the wetland macrophytes Phragmites australis, Arundo donax, Typha domingensis, Apium nodiflorum, and Nasturtium officinale. Results showed that the bioaccumulation capacity from sediments, translocation, total levels in plant tissues, and bioindication of metals in sediments, are generally species-specific. In particular, the patterns of metals in the aquatic plants studied were overall independent of ecology (coasts vs wetlands), biomass, anatomy (rhizomatous vs non rhizomatous plants), and life form (hemicrytophytes vs hydrophytes)...
January 15, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/27717118/diet-related-gut-bacterial-dysbiosis-correlates-with-impaired-development-increased-mortality-and-nosema-disease-in-the-honeybee-apis-mellifera
#13
Patrick W Maes, Pedro A P Rodrigues, Randy Oliver, Brendon M Mott, Kirk E Anderson
Dysbiosis, defined as unhealthy shifts in bacterial community composition, can lower the colonization resistance of the gut to intrinsic pathogens. Here, we determined the effect of diet age and type on the health and bacterial community composition of the honeybee (Apis mellifera). We fed newly emerged bees fresh or aged diets, and then recorded host development and bacterial community composition from four distinct regions of the hosts' digestive tract. Feeding fresh pollen or fresh substitute, we found no difference in host mortality, diet consumption, development or microbial community composition...
September 26, 2016: Molecular Ecology
https://www.readbyqxmd.com/read/27604234/transcriptional-profiling-of-genes-involved-in-ascorbic-acid-biosynthesis-recycling-and-degradation-during-three-leaf-developmental-stages-in-celery
#14
Wei Huang, Guang-Long Wang, Hui Li, Feng Wang, Zhi-Sheng Xu, Ai-Sheng Xiong
Ascorbic acid (AsA) is an important nutrient in the human body and performs various healthy functions. With considerable medicinal properties, celery (Apium graveolens L.) could be a good source of AsA for human health. However, the biosynthetic, recycling, and degradation pathways of AsA in celery have yet to be characterized. To study the metabolic pathways involved in AsA, the genes involved in AsA biosynthesis, recycling, and degradation were isolated from celery, and their expression profiles and AsA levels were analyzed in the leaf blades and petioles of two celery varieties at three different growth stages...
December 2016: Molecular Genetics and Genomics: MGG
https://www.readbyqxmd.com/read/27462548/the-effect-of-celery-apium-graveolens-on-reproductive-parameters-in-male-wistar-rat
#15
Wesam Kooti, Najmeh Kafash-Farkhad, Ali Ghorbani Ranjbary, Naim Sharafi-Ahvazi
No abstract text is available yet for this article.
May 2016: Avicenna Journal of Phytomedicine
https://www.readbyqxmd.com/read/27439966/l-3-n-butylphthalide-rescues-hippocampal-synaptic-failure-and-attenuates-neuropathology-in-aged-app-ps1-mouse-model-of-alzheimer-s-disease
#16
Yu Zhang, Long-Jian Huang, Si Shi, Shao-Feng Xu, Xiao-Liang Wang, Ying Peng
AIMS: Our previous studies showed that L-3-n-butylphthalide (L-NBP), an extract from seeds of Apium graveolens Linn (Chinese celery), improved cognitive ability in animal models of cerebral ischemia, vascular dementia, and Alzheimer's disease (AD). It is well known that cognitive deficit of AD is caused by synaptic dysfunction. In this study, we investigated the effect of L-NBP on hippocampal synaptic function in APP/PS1 AD transgenic mice and related mechanisms. METHODS: Eighteen-month-old APP/PS1 transgenic (Tg) mice were administrated 15 mg/kg L-NBP by oral gavage for 3 months...
December 2016: CNS Neuroscience & Therapeutics
https://www.readbyqxmd.com/read/27390722/effects-of-apium-graveolens-extract-on-the-oxidative-stress-in-the-liver-of-adjuvant-induced-arthritic-rats
#17
Wanida Sukketsiri, Pennapa Chonpathompikunlert, Supita Tanasawet, Nutjanat Choosri, Tulaporn Wongtawatchai
Apium graveolens Linn. (Apiaceae) is an indigenous plant of the North and South Americas, Southern Europe, and Asia and has been widely used as a food or a traditional medicine for treatment of inflammation and arthritis. The purpose of this study was to investigate the antioxidant effects of a methanolic extract of A. graveolens (AGE) against liver oxidative stress in an adjuvant-induced arthritic rat model. The AGE (250, 500, and 1,000 mg/kg) was given orally for 24 consecutive days after induction by injecting complete Freund's adjuvant...
June 2016: Preventive Nutrition and Food Science
https://www.readbyqxmd.com/read/27041871/review-of-scientific-evidence-of-medicinal-convoy-plants-in-traditional-persian-medicine
#18
REVIEW
Seyede Nargess Sadati, Mohammad Reza Shams Ardekani, Nastaran Ebadi, Maryam Yakhchali, Azadeh Raees Dana, Fatemeh Masoomi, Mahnaz Khanavi, Farid Ramezany
One concept used in traditional Persian medicine (TPM) for multidrug therapy is that of the convoy drug (Mobadregh). According to TPM texts, convoy drugs are substances (or drugs), which facilitate the access of drugs or foods to the whole body or to specific organs. This study reviewed some convoy drugs presented in TPM, their biological effects, and their probable interactions with main drugs, considering the increased absorption through inhibition of P-glycoprotein (P-gp) efflux function, bioavailability-enhancing effects, and decreased metabolism of the main drug using electronic databases including PubMed, Scopus, ScienceDirect, and Google Scholar in November and December, 2013...
January 2016: Pharmacognosy Reviews
https://www.readbyqxmd.com/read/27040538/usefulness-of-different-vascular-plant-species-for-passive-biomonitoring-of-mediterranean-rivers
#19
Daniela Baldantoni, Anna Alfani
Choosing native vascular plants as nutrient and toxic element accumulators for passive biomonitoring of urban river quality is not an easy task in Mediterranean rivers, due to the particular climate determining high variations in river hydrology. To identify potential biomonitors for this area, the roots of seven species (Angelica sylvestris, Apium nodiflorum, Tradescantia fluminensis, Nasturtium officinale, Persicaria lapathifolia, Arctium lappa, Typha latifolia), growing in seven sites along the River Irno (Southern Italy), were collected in July 2010 and analyzed regarding their capability to accumulate Cd, Cr, Cu, Fe, K, Mg, Mn, Na, Ni, Pb, V, and Zn through atomic absorption spectrometry...
July 2016: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/27014330/validation-and-comparison-of-reference-genes-for-qpcr-normalization-of-celery-apium-graveolens-at-different-development-stages
#20
Meng-Yao Li, Feng Wang, Qian Jiang, Guan-Long Wang, Chang Tian, Ai-Sheng Xiong
A suitable reference gene is an important prerequisite for guarantying accurate and reliable results in qPCR analysis. Celery is one of the representative vegetable in Apiaceae and is widely cultivated and consumed in the world. However, no reports have been previously published concerning reference genes in celery. In this study, the expression stabilities of nine candidate reference genes in leaf blade and petiole at different development stages were evaluated using three statistics algorithms geNorm, NormFinder, and BestKeeper...
2016: Frontiers in Plant Science
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