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https://www.readbyqxmd.com/read/28607886/managing-rhinophyma-by-trimodal-therapy-novel-approach
#1
K V Vishwas, Belliappa Pemmanda Raju, Umashankar Nagaraju
Rhinophyma is characterized by nodular thickening of the Nasal skin, sebaceous gland hyperplasia, dilated pores, and in its late stage, fibrosis. In severe cases, it results in loss of normal facial contours, significant disfigurement, and social isolation. Treatment options for severe rhinophyma include cryosurgery, partial-thickness decortications with subsequent secondary reepithelialisation, laser ablation, full thickness resection with graft or flap reconstruction, excision by electrocautery or radio frequency...
June 2017: Indian Journal of Otolaryngology and Head and Neck Surgery
https://www.readbyqxmd.com/read/28367260/a-single-blind-split-face-randomized-pilot-study-comparing-the-effects-of-intradermal-and-intramuscular-injection-of-two-commercially-available-botulinum-toxin-a-formulas-to-reduce-signs-of-facial-aging
#2
Priya Sapra, Shantel Demay, Sheetal Sapra, Julie Khanna, Kelli Mraud, Jennifer Bonadonna
Objective: To examine the effectiveness of intradermal botulinum toxin type A injection in improving skin texture and midface lift while reducing pore size and sebum production, as well as investigate the differences in effectiveness between onabotulinumtoxinA and abobotulinumtoxinA using intradermal and intramuscular injection methods. Design: A 16-week, single-blind, split-face, randomized study. Each patient served as their own control, receiving onabotulinumtoxinA and abobotulinumtoxinA randomized to either the left or right side of the face...
February 2017: Journal of Clinical and Aesthetic Dermatology
https://www.readbyqxmd.com/read/28178096/relative-location-of-fundus-meatus-acustici-interni-via-porus-acusticus-internus-in-facial-nerve-decompression
#3
Xu Liu, Haodong Wang, Kailiang Cheng, Youqiong Li
Facial neural edema is the pathophysiological base of Bell's palsy. The middle cranial fossa approach is used to relieve the oppression of facial nerve at its most narrow course in the facial canal. In this research, the authors mainly discussed the internal auditory canal segment of facial nerve, completely in the shadow of the bony structure, which is inconvenient for transmastoid decompression. Therefore, the objective was to explore the definite position of the fundus meatus acustici interni from internal acoustic pore...
February 7, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28162855/histopathological-and-scanning-electron-microscopy-findings-of-retrieved-porous-polyethylene-implants
#4
S-Y Choi, H-I Shin, T-Y Kwon, T-G Kwon
Porous polyethylene (PPE) implants are biocompatible alloplastic materials commonly used for facial augmentation. However, the effect of sub-periosteal PPE application on the surrounding tissues has not been analyzed clearly. This report documents the case of a 22-year-old woman who underwent peri-alar augmentation with PPE to improve midface retrusion. Although no infection or inflammation occurred at the surgical site, the patient requested removal of the PPE implant for aesthetic reasons alone at 1 year after the surgery...
February 2, 2017: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28095530/the-anti-aging-effects-of-low-oxygen-tension-generated-multipotent-growth-factor-containing-serum
#5
Zoe Diana Draelos, Jwala Karnik, Gail Naughton
Growth factors are a new category of ingredient found in modern cosmeceutical formulations. One novel method of obtaining cosmeceutical growth factors is the use of a bioreactor to culture neonatal broblasts on dextran microcarrier beads for 8 weeks under low oxygen tension (1-5%) mimicking embryonic conditions and eliminating the need for fetal bovine serum constituents in the final cosmetic material. This research evaluated the ingredient in a moisturizing vehicle on 40 females to determine its efficacy in improving overall facial skin appearance, as well as skin brightness, evenness, firmness, pore size, radiance, fine lines, coarse wrinkles, and blotchiness/ dispigmentation...
January 1, 2017: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/28001040/nanocomposite-membranes-via-the-codeposition-of-polydopamine-polyethylenimine-with-silica-nanoparticles-for-enhanced-mechanical-strength-and-high-water-permeability
#6
Yan Lv, Yong Du, Wen-Ze Qiu, Zhi-Kang Xu
A defect-free and stable selective layer is of critical significance for thin film composite membrane with excellent separation performance and service durability. We report a facial strategy for fabricating thin film nanocomposite (TFN) nanofltration membranes (NFMs) based on the codeposition of polydopamine, polyetheylenimine, and silica nanoparticles. Tripled water flux can be obtained from the TFN NFMs as compared with those NFMs without silica nanoparticles. This is ascribed to the improved wettability of the membrane surfaces and the enlarged pore sizes of the selective layer...
January 9, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/27885713/a-new-tool-to-quantify-the-geometrical-characteristics-of-facial-skin-pores-changes-with-age-and-a-making-up-procedure-in-caucasian-women
#7
A Shaiek, F Flament, G François, V Lefebvre-Descamps, C Barla, M Vicic, F Giron, R Bazin
BACKGROUND: Facial skin pores (FSP) are common and benign signs that generate frequent esthetic concerns or complaints. Despite their worldwide prevalence, related literature remains scarce. Hence, a new device has been developed and applied to validating studies, aiming at best describing FSP as they are self-perceived, i.e. their anatomic features, their possible alterations with age and their appearance after application of a make-up product. METHODS: Dermascore+(®) is an imaging device dedicated to a direct observation and acquisition of various characteristics of the skin surface...
May 2017: Skin Research and Technology
https://www.readbyqxmd.com/read/27800641/automatic-facial-pore-analysis-system-using-multi-scale-pore-detection
#8
J Y Sun, S W Kim, S H Lee, J E Choi, S J Ko
BACKGROUND/PURPOSE: As facial pore widening and its treatments have become common concerns in the beauty care field, the necessity for an objective pore-analyzing system has been increased. Conventional apparatuses lack in usability requiring strong light sources and a cumbersome photographing process, and they often yield unsatisfactory analysis results. This study was conducted to develop an image processing technique for automatic facial pore analysis. METHODS: The proposed method detects facial pores using multi-scale detection and optimal scale selection scheme and then extracts pore-related features such as total area, average size, depth, and the number of pores...
November 1, 2016: Skin Research and Technology
https://www.readbyqxmd.com/read/27786580/postinflammatory-hyperpigmentation-associated-with-treatment-of-solar-lentigines-using-a-q-switched-532-nm-nd-yag-laser-a-multicenter-survey
#9
Hyun Ji Kang, Jung Im Na, Jong Hee Lee, Mi Ryung Roh, Joo Yeon Ko, Sung Eun Chang
PURPOSE: To characterize the risk factors of Korean patients for postinflammatory hyperpigmentation (PIH) during treatment of solar lentigines using a Q-switched 532-nm Nd: YAG (QS 532 NY) laser. MATERIALS AND METHODS: The present retrospective multicenter study was conducted at the dermatology clinics of five tertiary hospitals in Korea. Between October 2007 and January 2013, 516 patients were enrolled and reviewed for clinical features and factors associated with PIH...
November 15, 2016: Journal of Dermatological Treatment
https://www.readbyqxmd.com/read/27775445/evaluating-photographic-scales-of-facial-pores-and-diagnostic-agreement-of-tests-using-latent-class-models
#10
Yao Ning, Zeng Qing, Wang Qing, Li Li
BACKGROUND: Ordinal severity scales illustrated by photographs have been widely developed to help dermatologists in evaluating skin problems or improvements. Numerous scales have been published, and none of them were used for assessing facial pores. METHODS: A five-point photographic scale of facial pores was formulated, and photographs of pores on nasal ala from 128 female volunteers were acquired. Five dermatologists with similar experiences rated the 128 photographs independently using the reference photographs...
February 2017: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/27529707/enlarged-facial-pores-an-update-on-treatments
#11
REVIEW
Joanna Dong, Julien Lanoue, Gary Goldenberg
Enlarged facial pores remain a common dermatologic and cosmetic concern from acne and rosacea, among other conditions, that is difficult to treat due to the multifactorial nature of their pathogenesis and negative impact on patients' quality of life. Enlarged facial pores are primarily treated through addressing associative factors, such as increased sebum production and cutaneous aging. We review the current treatment modalities for enlarged or dense facial pores, including topical retinoids, chemical peels, oral antiandrogens, and lasers and devices, with a focus on newer therapies...
July 2016: Cutis; Cutaneous Medicine for the Practitioner
https://www.readbyqxmd.com/read/27151206/kcnk9-imprinting-syndrome-further-delineation-of-a-possible-treatable-disorder
#12
John M Graham, Neda Zadeh, Melissa Kelley, Ee Shien Tan, Wendy Liew, Victoria Tan, Matthew A Deardorff, Golder N Wilson, Lena Sagi-Dain, Stavit A Shalev
Patients with KCNK9 imprinting syndrome demonstrate congenital hypotonia, variable cleft palate, normal MRIs and EEGs, delayed development, and feeding problems. Associated facial dysmorphic features include dolichocephaly with bitemporal narrowing, short philtrum, tented upper lip, palatal abnormalities, and small mandible. This disorder maps to chromosomal region 8q24, and it is caused by a specific missense mutation 770G>A in exon 2, replacing glycine at position 236 by arginine (G236R) in the maternal copy of KCNK9 within this locus...
October 2016: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/27050699/combination-superficial-peels-with-salicylic-acid-and-post-peel-retinoids
#13
RANDOMIZED CONTROLLED TRIAL
Douglas E Kligman, Zoe D Draelos
BACKGROUND: Salicylic acid (SA) and retinoids, tretinoin (all-trans retinoic acid [ATRA]), and retinol (all-trans retinol) are widely used as topical agents for the improvement of photodamage and acne vulgaris. They can be used in daily take-home products or as part of an in-office procedure, combining the benefits of a keratolytic (SA) and a retinoid. OBJECTIVE: The objective of this research was to compare the efficacy for ameliorating photodamage of topical tretinoin (0...
April 2016: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/26918966/facial-pores-definition-causes-and-treatment-options
#14
REVIEW
Sang Ju Lee, Joon Seok, Se Yeong Jeong, Kui Young Park, Kapsok Li, Seong Jun Seo
BACKGROUND: Enlarged skin pores refer to conditions that present with visible topographic changes of skin surfaces. Although not a medical concern, enlarged pores are a cosmetic concern for a large number of individuals. Moreover, clear definition and possible causes of enlarged pores have not been elucidated. OBJECTIVE: To review the possible causes and treatment options for skin pores. METHODS: This article is based on a review of the medical literature and the authors' clinical experience in investigating and treating skin pores...
March 2016: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/26885789/jasmonates-and-tetrahydrojasmonic-acid-a-novel-class-of-anti-aging-molecules
#15
Macrene Alexiades
Jasmonates are plant-derived hormones from linoleic acid that were originally isolated from jasmine, and which are involved in plant stress regulation, wound repair and defense. They have been demonstrated through in vitro and in vivo studies to possess anti-neoplastic properties. Most recently, a novel jasmonate analog was developed, tetrahydrojasmonic acid (LR2412), which possesses favorable characteristics for cutaneous application and which induces improvements in epidermal hyaluronic acid and thickness...
February 2016: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/26763878/de-novo-missense-mutations-in-nalcn-cause-developmental-and-intellectual-impairment-with-hypotonia
#16
Ryoko Fukai, Hirotomo Saitsu, Nobuhiko Okamoto, Yasunari Sakai, Aviva Fattal-Valevski, Shiina Masaaki, Yukihiro Kitai, Michiko Torio, Kanako Kojima-Ishii, Kenji Ihara, Veronika Chernuha, Mitsuko Nakashima, Satoko Miyatake, Fumiaki Tanaka, Noriko Miyake, Naomichi Matsumoto
Three recessive mutations in the sodium leak channel, nonselective (NALCN) have been reported to cause intellectual disability and hypotonia. In addition, 14 de novo heterozygous mutations have been identified in 15 patients with arthrogryposis and neurodevelopmental impairment. Here, we report three patients with neurodevelopmental disease and hypotonia, harboring one recurrent (p.R1181Q) and two novel mutations (p.L312V and p.V1020F) occurring de novo in NALCN. Mutation p.L312 is located in the pore forming S6 region of domain I and p...
May 2016: Journal of Human Genetics
https://www.readbyqxmd.com/read/26690453/genipin-crosslinked-chitosan-gels-and-scaffolds-for-tissue-engineering-and-regeneration-of-cartilage-and-bone
#17
REVIEW
Riccardo A A Muzzarelli, Mohamad El Mehtedi, Carlo Bottegoni, Alberto Aquili, Antonio Gigante
The present review article intends to direct attention to the technological advances made since 2009 in the area of genipin-crosslinked chitosan (GEN-chitosan) hydrogels. After a concise introduction on the well recognized characteristics of medical grade chitosan and food grade genipin, the properties of GEN-chitosan obtained with a safe, spontaneous and irreversible chemical reaction, and the quality assessment of the gels are reviewed. The antibacterial activity of GEN-chitosan has been well assessed in the treatment of gastric infections supported by Helicobacter pylori...
December 11, 2015: Marine Drugs
https://www.readbyqxmd.com/read/26621776/differential-mechanisms-of-cant%C3%A3%C2%BA-syndrome-associated-gain-of-function-mutations-in-the-abcc9-sur2-subunit-of-the-katp-channel
#18
Paige E Cooper, Monica Sala-Rabanal, Sun Joo Lee, Colin G Nichols
Cantú syndrome (CS) is a rare disease characterized by congenital hypertrichosis, distinct facial features, osteochondrodysplasia, and cardiac defects. Recent genetic analysis has revealed that the majority of CS patients carry a missense mutation in ABCC9, which codes for the sulfonylurea receptor SUR2. SUR2 subunits couple with Kir6.x, inwardly rectifying potassium pore-forming subunits, to form adenosine triphosphate (ATP)-sensitive potassium (K(ATP)) channels, which link cell metabolism to membrane excitability in a variety of tissues including vascular smooth muscle, skeletal muscle, and the heart...
December 2015: Journal of General Physiology
https://www.readbyqxmd.com/read/26461829/%C3%AF-%C3%AF-topical-treatment-with-liposomal-sodium-copper-chlorophyllin-complex-in-subjects-with-facial-redness-and-erythematotelangiectatic-rosacea-case-studies
#19
David B Vasily
Physicians are often presented with patients complaining of facial redness and difficult to control rosacea. The water soluble sodium copper chlorophyllin complex has been shown to have anti-oxidant, anti-inflammatory, and anti-bacterial activities in vitro and anti-redness, pore reduction, and anti-acne activities in pilot clinical studies. In these case studies, the safety and efficacy of a topical gel containing a liposomal suspension of sodium copper chlorophyllin complex was assessed in subjects with facial redness and erythematotelangiectatic rosacea...
October 2015: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/26382054/treatment-of-frey-s-syndrome-with-topical-ammonium-alum-first-report-with-twenty-two-cases
#20
LETTER
N Chueasupparobon, W Rawangban, N Tangjaturonrasme
No abstract text is available yet for this article.
October 2016: Clinical Otolaryngology
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