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facial pores

Yao Ning, Zeng Qing, Wang Qing, Li Li
BACKGROUND: Ordinal severity scales illustrated by photographs have been widely developed to help dermatologists evaluating skin problems or improvements. Numerous scales have been published and none of them were used for assessing facial pores. METHODS: A five-point photographic scale of facial pores was formulated and photographs of pores on nasal ala from 128 female volunteers were acquired. Five dermatologists with similar experiences rated the 128 photographs independently using the reference photographs...
October 24, 2016: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
Joanna Dong, Julien Lanoue, Gary Goldenberg
Enlarged facial pores remain a common dermatologic and cosmetic concern from acne and rosacea, among other conditions, that is difficult to treat due to the multifactorial nature of their pathogenesis and negative impact on patients' quality of life. Enlarged facial pores are primarily treated through addressing associative factors, such as increased sebum production and cutaneous aging. We review the current treatment modalities for enlarged or dense facial pores, including topical retinoids, chemical peels, oral antiandrogens, and lasers and devices, with a focus on newer therapies...
July 2016: Cutis; Cutaneous Medicine for the Practitioner
John M Graham, Neda Zadeh, Melissa Kelley, Ee Shien Tan, Wendy Liew, Victoria Tan, Matthew A Deardorff, Golder N Wilson, Lena Sagi-Dain, Stavit A Shalev
Patients with KCNK9 imprinting syndrome demonstrate congenital hypotonia, variable cleft palate, normal MRIs and EEGs, delayed development, and feeding problems. Associated facial dysmorphic features include dolichocephaly with bitemporal narrowing, short philtrum, tented upper lip, palatal abnormalities, and small mandible. This disorder maps to chromosomal region 8q24, and it is caused by a specific missense mutation 770G>A in exon 2, replacing glycine at position 236 by arginine (G236R) in the maternal copy of KCNK9 within this locus...
October 2016: American Journal of Medical Genetics. Part A
Douglas E Kligman, Zoe D Draelos
BACKGROUND: Salicylic acid (SA) and retinoids, tretinoin (all-trans retinoic acid [ATRA]), and retinol (all-trans retinol) are widely used as topical agents for the improvement of photodamage and acne vulgaris. They can be used in daily take-home products or as part of an in-office procedure, combining the benefits of a keratolytic (SA) and a retinoid. OBJECTIVE: The objective of this research was to compare the efficacy for ameliorating photodamage of topical tretinoin (0...
April 2016: Journal of Drugs in Dermatology: JDD
Sang Ju Lee, Joon Seok, Se Yeong Jeong, Kui Young Park, Kapsok Li, Seong Jun Seo
BACKGROUND: Enlarged skin pores refer to conditions that present with visible topographic changes of skin surfaces. Although not a medical concern, enlarged pores are a cosmetic concern for a large number of individuals. Moreover, clear definition and possible causes of enlarged pores have not been elucidated. OBJECTIVE: To review the possible causes and treatment options for skin pores. METHODS: This article is based on a review of the medical literature and the authors' clinical experience in investigating and treating skin pores...
March 2016: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
Macrene Alexiades
Jasmonates are plant-derived hormones from linoleic acid that were originally isolated from jasmine, and which are involved in plant stress regulation, wound repair and defense. They have been demonstrated through in vitro and in vivo studies to possess anti-neoplastic properties. Most recently, a novel jasmonate analog was developed, tetrahydrojasmonic acid (LR2412), which possesses favorable characteristics for cutaneous application and which induces improvements in epidermal hyaluronic acid and thickness...
February 2016: Journal of Drugs in Dermatology: JDD
Ryoko Fukai, Hirotomo Saitsu, Nobuhiko Okamoto, Yasunari Sakai, Aviva Fattal-Valevski, Shiina Masaaki, Yukihiro Kitai, Michiko Torio, Kanako Kojima-Ishii, Kenji Ihara, Veronika Chernuha, Mitsuko Nakashima, Satoko Miyatake, Fumiaki Tanaka, Noriko Miyake, Naomichi Matsumoto
Three recessive mutations in the sodium leak channel, nonselective (NALCN) have been reported to cause intellectual disability and hypotonia. In addition, 14 de novo heterozygous mutations have been identified in 15 patients with arthrogryposis and neurodevelopmental impairment. Here, we report three patients with neurodevelopmental disease and hypotonia, harboring one recurrent (p.R1181Q) and two novel mutations (p.L312V and p.V1020F) occurring de novo in NALCN. Mutation p.L312 is located in the pore forming S6 region of domain I and p...
May 2016: Journal of Human Genetics
Riccardo A A Muzzarelli, Mohamad El Mehtedi, Carlo Bottegoni, Alberto Aquili, Antonio Gigante
The present review article intends to direct attention to the technological advances made since 2009 in the area of genipin-crosslinked chitosan (GEN-chitosan) hydrogels. After a concise introduction on the well recognized characteristics of medical grade chitosan and food grade genipin, the properties of GEN-chitosan obtained with a safe, spontaneous and irreversible chemical reaction, and the quality assessment of the gels are reviewed. The antibacterial activity of GEN-chitosan has been well assessed in the treatment of gastric infections supported by Helicobacter pylori...
December 2015: Marine Drugs
Paige E Cooper, Monica Sala-Rabanal, Sun Joo Lee, Colin G Nichols
Cantú syndrome (CS) is a rare disease characterized by congenital hypertrichosis, distinct facial features, osteochondrodysplasia, and cardiac defects. Recent genetic analysis has revealed that the majority of CS patients carry a missense mutation in ABCC9, which codes for the sulfonylurea receptor SUR2. SUR2 subunits couple with Kir6.x, inwardly rectifying potassium pore-forming subunits, to form adenosine triphosphate (ATP)-sensitive potassium (K(ATP)) channels, which link cell metabolism to membrane excitability in a variety of tissues including vascular smooth muscle, skeletal muscle, and the heart...
December 2015: Journal of General Physiology
David B Vasily
Physicians are often presented with patients complaining of facial redness and difficult to control rosacea. The water soluble sodium copper chlorophyllin complex has been shown to have anti-oxidant, anti-inflammatory, and anti-bacterial activities in vitro and anti-redness, pore reduction, and anti-acne activities in pilot clinical studies. In these case studies, the safety and efficacy of a topical gel containing a liposomal suspension of sodium copper chlorophyllin complex was assessed in subjects with facial redness and erythematotelangiectatic rosacea...
October 2015: Journal of Drugs in Dermatology: JDD
N Chueasupparobon, W Rawangban, N Tangjaturonrasme
No abstract text is available yet for this article.
October 2016: Clinical Otolaryngology
Lai Hsin-Ti, Liu Wen-Sheng, Wu Yi-Chia, Lai Ya-Wei, Zhi-Hong Wen, Wang Hui-Min David, Lee Su-Shin
BACKGROUND: Anti-aging skin care is a growing popular topic in cosmetic and aesthetic fields, and skin care rather then makeup tips draw more attention nowadays. The phenomenon of skin aging includes thinning of skin losses of elasticity and moisture, pigmented spot formation, and wrinkle development. Along with growth in age, the decreased rates of epithelium renewal and cellular recovery as well as the reduced contents of elastin, collagen, and glycosaminoglycans all contribute to creases or folds of skin...
2015: Current Pharmaceutical Biotechnology
Thomas J Stephens, John P McCook, James H Herndon
BACKGROUND: Acne vulgaris is one of the most common skin diseases treated by dermatologists. Salts of copper chlorophyllin complex are semi-synthetic naturally-derived compounds with antioxidant, anti-inflammatory and wound healing activity that have not been previously tested topically in the treatment of acne-prone skin with enlarged pores. OBJECTIVES: This single-center pilot study was conducted to assess the efficacy and safety of a liposomal dispersion of topically applied sodium copper chlorophyllin complex in subjects with mild-moderate acne and large, visible pores over a course of 3 weeks...
June 2015: Journal of Drugs in Dermatology: JDD
Dong Hye Suh, Hee Won Jang, Sang Jun Lee, Won Seok Lee, Hwa Jung Ryu
BACKGROUND: Thread lifting is a minimally invasive technique for facial rejuvenation. Various devices for thread lifting using polydioxanone (PDO) are popular in aesthetic clinics in Korea, but there have been a few studies regarding its use. OBJECTIVE: To describe PDO thread and techniques adopted to counteract the descent and laxity of the face. METHODS: A retrospective chart review was conducted over a 24-month period. A total of 31 thread lifting procedures were performed...
June 2015: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
Bing Ding, Zhi Chang, Guiyin Xu, Ping Nie, Jie Wang, Jin Pan, Hui Dou, Xiaogang Zhang
Given their high theoretical energy density, lithium-sulfur (Li-S) batteries have recently attracted ever-increasing research interest. However, the dissolution of polysulfides and uncontrolled deposition of insoluble discharge product significantly hinder the cycling stability. Herein, a nanospace-confinement copolymerization strategy for encapsulating polymeric sulfur into porous carbon matrix is presented. The morphologies and sulfur contents of carbon/polymeric sulfur (C/PS) composites could be readily tailored by controlling the copolymerization time...
June 3, 2015: ACS Applied Materials & Interfaces
Huizhen Chen, Chnagtao Liu, Jie Yin, Zhen Chen, Jinwang Xu, Duanlei Wang, Jiaqiu Zhu, Ziyuan Zhang, Yong Sun, Aimin Li
Many studies have demonstrated that ischemia could induce facial nerve (FN) injury. However, there is a lack of a suitable animal model for FN injury study and thus little knowledge is available about the precise mechanism for FN injury. The aims of this study were to establish a reliable FN injury model induced by blocking the petrosal artery and to investigate whether dysfunctional interaction between cyclophilin D (CypD) and mitochondrial permeability transition pore (MPTP) can mediate cell dysfunction in ischemic FN injury...
October 2015: Cellular and Molecular Neurobiology
Dong Li, Huiling Zhou, Kin-Man Lam
Face recognition methods, which usually represent face images using holistic or local facial features, rely heavily on alignment. Their performances also suffer a severe degradation under variations in expressions or poses, especially when there is one gallery per subject only. With the easy access to high-resolution (HR) face images nowadays, some HR face databases have recently been developed. However, few studies have tackled the use of HR information for face recognition or verification. In this paper, we propose a pose-invariant face-verification method, which is robust to alignment errors, using the HR information based on pore-scale facial features...
August 2015: IEEE Transactions on Image Processing: a Publication of the IEEE Signal Processing Society
Frederic Flament, Ghislain Francois, Huixia Qiu, Chengda Ye, Tomoo Hanaya, Dominique Batisse, Suzy Cointereau-Chardon, Mirela Donato Gianeti Seixas, Susi Elaine Dal Belo, Roland Bazin
Skin pores (SP), as they are called by laymen, are common and benign features mostly located on the face (nose, cheeks, etc) that generate many aesthetic concerns or complaints. Despite the prevalence of skin pores, related literature is scarce. With the aim of describing the prevalence of skin pores and anatomic features among ethnic groups, a dermatoscopic instrument, using polarized lighting, coupled to a digital camera recorded the major features of skin pores (size, density, coverage) on the cheeks of 2,585 women in different countries and continents...
2015: Clinical, Cosmetic and Investigational Dermatology
Timothy R Ruhnke, Janine N Caira, Allison Cox
The spiral intestines of a total of 30 specimens of 14 species of batoids from around the world were examined for rhinebothriideans. These consisted of Taeniura grabata, Dasyatis margaritella, and Dasyatis sp. from Senegal, Dasyatis americana from Florida, Dasyatis dipterura and Dasyatis longa from México, Himantura jenkinsii, Himantura leoparda, Himantura uarnak 2, Urogymnus asperrimus 1, and Neotrygon kuhlii 4 from Australia, in addition to Himantura uarnacoides and Neotrygon kuhlii 1 from Borneo. Each of these hosted one or more species of Anthocephalum...
2015: Zootaxa
María A Pérez-Maciá, David Curcó, Roger Bringué, Montserrat Iborra, Carlos Alemán
The microscopic structures of highly crosslinked sulfonated poly(styrene-co-divinylbenzene) resins have been modeled by generating atomistic microstructures using stochastic-like algorithms, which are subsequently relaxed using molecular dynamics. Two different generation algorithms have been tested. The relaxation of the microstructures generated by the first algorithm, which is based on a homogeneous construction of the resin, leads to a significant overestimation of the experimental density as well as to an unsatisfactory description of the porosity...
March 21, 2015: Soft Matter
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