keyword
https://read.qxmd.com/read/38051835/a-pilot-study-to-evaluate-the-efficacy-and-tolerability-of-a-topical-combination-serum-for-the-improvement-of-aged-skin
#1
JOURNAL ARTICLE
(no author information available yet)
BACKGROUND: With intrinsic aging, the epidermis becomes thinner and fine wrinkles appear. Extrinsic aging, or photoaging, is characterized by deep wrinkles, skin laxity, and hyperpigmentation. OBJECTIVE: To evaluate the efficacy and safety of a novel combination serum with retinol, hyaluronic acid, and trichloroacetic acid (Test Product) for the improvement of aged facial skin. METHODS: Female subjects (n=22) enrolled in the single-site, open-label, pilot study...
December 1, 2023: Journal of Drugs in Dermatology: JDD
https://read.qxmd.com/read/37610009/quantitative-assessment-of-the-effects-of-botulinum-toxin-on-skin-perfusion-by-laser-doppler-flowmetry-a-clinical-trial
#2
JOURNAL ARTICLE
Ozan Balik
Several studies reported an increase in skin glow, pore shrinkage, and an improvement in oily skin with its mesobotox-like use. The authors aimed to determine the extent of late changes in skin perfusion in the superficial dermis when Botulinium toxin A (Btx-A) is injected into the skin with mesotherapy, independent of any stimulant and surgery, using a laser Doppler flowmeter for analysis. Btx-A was applied to the right cheek and saline mesotherapy to the left cheeks of a total of 9 subjects. Two weeks later, their contribution to skin circulation was measured by the laser Doppler flowmeter...
August 23, 2023: Journal of Craniofacial Surgery
https://read.qxmd.com/read/34331184/unusual-phenotypes-in-patients-with-a-pathogenic-germline-variant-in-dicer1
#3
JOURNAL ARTICLE
Kateryna Venger, Miriam Elbracht, Julia Carlens, Peter Deutz, Felix Zeppernick, Lisa Lassay, Christian Kratz, Martin Zenker, Jung Kim, Douglas R Stewart, Ilse Wieland, Kris Ann P Schultz, Nicolaus Schwerk, Ingo Kurth, Udo Kontny
Pathogenic germline DICER1 variants are associated with pleuropulmonary blastoma, multinodular goiter, embryonal rhabdomyosarcoma and other tumour types, while mosaic missense DICER1 variants in the RNase IIIb domain are linked to cause GLOW (global developmental delay, lung cysts, overgrowth, and Wilms' tumor) syndrome. Here, we report four families with germline DICER1 pathogenic variants in which one member in each family had a more complex phenotype, including skeletal findings, facial dysmorphism and developmental abnormalities...
July 31, 2021: Familial Cancer
https://read.qxmd.com/read/34224600/in-elderly-caucasian-women-younger-facial-perceived-age-correlates-with-better-forearm-skin-microcirculation-reactivity
#4
JOURNAL ARTICLE
Christelle Guéré, Armelle Bigouret, Alex Nkengne, Katell Vié, Anthony Gélis, Joshua Dulong, Jérôme Lamartine, Bérengère Fromy
BACKGROUND: Visual and molecular changes occurring upon aging are rather well characterized. Still, aging signs show great significant inter-individual variations, and little is known concerning the link between perceived age and cutaneous microcirculation. MATERIALS AND METHODS: To investigate this point, we recruited Caucasian women in their mid-50's to mid-70's and subsampled women looking older or younger than their age. We studied their facial skin color, as well as their microvascular reactivity to local heating assessed in the forearm skin...
July 5, 2021: Skin Research and Technology
https://read.qxmd.com/read/34197658/evaluating-the-respective-weights-of-some-facial-signs-on-the-perceived-radiance-glow-in-differently-aged-women-of-six-countries
#5
JOURNAL ARTICLE
Frederic Flament, Chengda Ye, Daiane Garcia Mercurio, Aurelie Abric, Poonam Sewraj, Damien Velleman, Sawako Yamamoto, Anne Prunel, Loic Colomb
OBJECTIVES: To evaluate the impact of Facial radiance or Glow on the perception of age (PA) and to assess which facial signs most influence PA. MATERIAL AND METHODS: The faces of 1058 differently aged women (18-80 years) of six different ethnicities/countries (China, Japan, Korea, India, South Africa, and Brazil) were photographed under standard conditions. These allowed to focus on 20 different facial signs that were further graded by experts, using referential Atlases dedicated to facial aging...
July 1, 2021: Skin Research and Technology
https://read.qxmd.com/read/34162278/the-glow-still-shows-effects-of-facial-masking-on-perceptions-of-duchenne-versus-social-smiles
#6
JOURNAL ARTICLE
Kennon M Sheldon, Ryan Goffredi, Mike Corcoran
Facial expressions of emotion have important communicative functions. It is likely that mask-wearing during pandemics disrupts these functions, especially for expressions defined by activity in the lower half of the face. We tested this by asking participants to rate both Duchenne smiles (DSs; defined by the mouth and eyes) and non-Duchenne or "social" smiles (SSs; defined by the mouth alone), within masked and unmasked target faces. As hypothesized, masked SSs were rated much lower in "a pleasant social smile" and much higher in "a merely neutral expression," compared with unmasked SSs...
June 24, 2021: Perception
https://read.qxmd.com/read/32854171/bleaching-and-skin-lightening-practice-among-female-students-in-south-india-a-cross-sectional-survey
#7
JOURNAL ARTICLE
Soumya Jagadeesan, Feroze Kaliyadan, Karalikkattil T Ashique, Aditi Karunakaran
BACKGROUND: Bleaching with skin-lightening preparations is a common practice in our society. Particularly, a practice simply known as "bleaching"-referring to application of skin-lightening chemicals including ammonia, hydrogen peroxide, and hypochlorite, repeated at intervals, as a salon-based or home-based procedure appears wide-spread among young females in India. However, there is limited medical literature on "bleaching." AIMS: We aimed to estimate the prevalence of "bleaching" among female students of our campus and to assess the knowledge, attitude, and practices regarding "bleaching" in the same population...
August 27, 2020: Journal of Cosmetic Dermatology
https://read.qxmd.com/read/32643159/facial-signs-changes-with-age-and-their-respective-weights-on-perceived-ages-tired-look-or-healthy-glow-among-differently-aged-chinese-men
#8
JOURNAL ARTICLE
Frederic Flament, Aurelie Abric, David Amar, Chengda Ye, Johanna Caron, Caroline Negre
OBJECTIVE: To determine the respective weights of certain facial signs on the assessment of perceived age, tired-look and healthy glow on Chinese men of different ages. MATERIAL AND METHODS: Photographs were taken of the faces of 420 Chinese men of different ages, under standardized conditions. These photographs allowed to focus and define 15 facial signs, which were then graded by 15 experts and dermatologists, using standardized scales provided by a reference Skin Aging Atlas...
July 8, 2020: International Journal of Cosmetic Science
https://read.qxmd.com/read/31799996/effect-of-topical-brimonidine-on-alcohol-induced-flushing-in-asian-individuals-a-randomized-clinical-trial
#9
RANDOMIZED CONTROLLED TRIAL
Wesley Y Yu, Brian Lu, Daniel Tan, Christine Aroyan, Kanade Shinkai, Kieron S Leslie, Lindy P Fox, Siegrid Yu, Isaac M Neuhaus, Roy C Grekin, Sarah T Arron
IMPORTANCE: Alcohol flushing syndrome (AFS, also known as Asian glow and Asian flush) affects 20% to 47% of East Asians and causes significant psychosocial distress. There are no approved treatments for this condition. OBJECTIVE: To determine whether brimonidine gel, 0.33%, decreases facial erythema in patients with AFS after consumption of alcohol. DESIGN, SETTING, AND PARTICIPANTS: In this randomized clinical trial, 20 healthy volunteers of East Asian descent with a self-reported history of AFS were recruited between April 2018 and March 2019...
February 1, 2020: JAMA Dermatology
https://read.qxmd.com/read/31165929/the-growth-rate-and-the-positive-prediction-of-needle-biopsy-of-clinically-diagnosed-warthin-s-tumor
#10
JOURNAL ARTICLE
Jungirl Seok, Woo-Jin Jeong, Soon-Hyun Ahn, Young Ho Jung
PURPOSE: This study reports the clinical course, including the growth rate, of Warthin's tumor (WT) and evaluates the positive prediction of needle biopsy for WT. METHODS: The medical records of 182 patients clinically diagnosed with WT were retrospectively reviewed. Tumor growth rates were measured in patients who underwent serial radiologic exams with minimum 6-month time intervals, and the positive prediction value (PPV) of needle biopsy was evaluated in comparison with surgical pathology in patients who underwent surgical excision of the tumors...
July 2019: European Archives of Oto-rhino-laryngology
https://read.qxmd.com/read/28368135/the-ugliness-in-averageness-effect-tempering-the-warm-glow-of-familiarity
#11
JOURNAL ARTICLE
Evan W Carr, David E Huber, Diane Pecher, Rene Zeelenberg, Jamin Halberstadt, Piotr Winkielman
Mere exposure (i.e., stimulus repetition) and blending (i.e., stimulus averaging) are classic ways to increase social preferences, including facial attractiveness. In both effects, increases in preference involve enhanced familiarity. Prominent memory theories assume that familiarity depends on a match between the target and similar items in memory. These theories predict that when individual items are weakly learned, their blends (morphs) should be relatively familiar, and thus liked-a beauty-in-averageness effect ( BiA )...
June 2017: Journal of Personality and Social Psychology
https://read.qxmd.com/read/23426745/aging-changes-of-the-periorbita-cheeks-and-midface
#12
JOURNAL ARTICLE
William H Truswell
The periorbita, cheeks, and midface are an area of complex facial form and function. There is a particular pleasing visual harmony of these regions in the youthful face. With time, the robust glow and fullness of youth fades and diminishes. The skin is the first component to show the passage of time as it dulls, wrinkles, and blemishes. This is followed by a slow loosening and sagging of soft tissues as they descend from their once-fixed points of the skeletal foundation. The smooth transitions between regions are separated and hollows and ridges appear...
February 2013: Facial Plastic Surgery: FPS
https://read.qxmd.com/read/21507069/differences-in-the-surface-and-subsurface-reflection-characteristics-of-facial-skin-by-age-group
#13
JOURNAL ARTICLE
Akira Matsubara
BACKGROUND/PURPOSE: The age-dependent changes of facial skin imperfections such as spot or wrinkles have been investigated repeatedly by means of various objective measurements. However, the age-dependent changes in the optical-reflection characteristics that create a perception of a shine or a glow of the skin have received little attention. We evaluated the age dependence of the optical-reflection characteristics of the surface and subsurface facial skin layers of three age groups. METHODOLOGY: The facial skin of 83 Japanese females ranging in age from 20 to 49 years was examined using a high-resolution digital camera equipped with a linear polarizing filter under polarized illumination...
February 2012: Skin Research and Technology
https://read.qxmd.com/read/20424063/happiness-cools-the-warm-glow-of-familiarity-psychophysiological-evidence-that-mood-modulates-the-familiarity-affect-link
#14
JOURNAL ARTICLE
Marieke de Vries, Rob W Holland, Troy Chenier, Mark J Starr, Piotr Winkielman
People often prefer familiar stimuli, presumably because familiarity signals safety. This preference can occur with merely repeated old stimuli, but it is most robust with new but highly familiar prototypes of a known category (beauty-in-averageness effect). However, is familiarity always warm? Tuning accounts of mood hold that positive mood signals a safe environment, whereas negative mood signals an unsafe environment. Thus, the value of familiarity should depend on mood. We show that compared with a sad mood, a happy mood eliminates the preference for familiar stimuli, as shown in measures of self-reported liking and physiological measures of affect (electromyographic indicator of spontaneous smiling)...
March 2010: Psychological Science
https://read.qxmd.com/read/8142115/treatment-of-photoaged-skin-with-topical-tretinoin
#15
REVIEW
A M Kligman, J J Leyden
Once-daily application of tretinoin to photodamaged facial skin for 0-12 months results in substantial clinical and histologic improvement. As regards appearance, fine wrinkles become effaced, dyspigmentations fade, surface becomes smooth and develops a 'rosy glow'. Histologically, atrophy and dysplasia of the epidermis are completely corrected. New collagen is laid down subepidermally along with the development of new small vessels (angiogenesis). Mesenchymal dermal cells become more numerous and larger. The sum of changes is toward more youthful skin...
1993: Skin Pharmacology: the Official Journal of the Skin Pharmacology Society
https://read.qxmd.com/read/3486402/red-man-syndrome-inadvertent-administration-of-an-excessive-dose-of-rifampin-to-children-in-a-day-care-center
#16
JOURNAL ARTICLE
G Bolan, R E Laurie, C V Broome
A cluster of toxic reactions among children inadvertently given excessive doses of rifampin for chemoprophylaxis of invasive Haemophilus influenzae disease in a day-care center was investigated. In all 19 children, who received five times the therapeutic dose of rifampin, dramatic adverse reactions developed. A striking, "glowing" red discoloration of the skin and facial or periorbital edema were found to be the hallmarks of rifampin toxicity. These clinical signs of acute toxicity contrast sharply with the adverse side effects of rifampin reported with therapeutic doses...
May 1986: Pediatrics
https://read.qxmd.com/read/2612105/-wallenberg-s-syndrome-in-a-case-of-vogt-koyanagi-harada-disease
#17
JOURNAL ARTICLE
E Nitta, M Takamori
A 45-year-old Japanese man, who had had bilateral visual disturbance due to Vogt-Koyanagi-Harada (VKH) disease 17 years before entry, was admitted to this hospital because of headache, vertigo and vomiting. On examination at entry, no abnormalities except for poliosis, patches of vitiligo on his left shin, sunset glow fundus, and positional nystagmus with Frenzel glasses were found. Laboratory data other than leukocytosis and elevated level of gamma-GTP were normal and the results of brain CT scan were within normal limits...
April 1989: Rinshō Shinkeigaku, Clinical Neurology
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