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https://www.readbyqxmd.com/read/28508256/the-role-of-micronutrients-in-alopecia-areata-a-review
#1
REVIEW
Jordan M Thompson, Mehwish A Mirza, Min Kyung Park, Abrar A Qureshi, Eunyoung Cho
Alopecia areata (AA) is a common, non-scarring form of hair loss caused by immune-mediated attack of the hair follicle. As with other immune-mediated diseases, a complex interplay between environment and genetics is thought to lead to the development of AA. Deficiency of micronutrients such as vitamins and minerals may represent a modifiable risk factor associated with development of AA. Given the role of these micronutrients in normal hair follicle development and in immune cell function, a growing number of investigations have sought to determine whether serum levels of these nutrients might differ in AA patients, and whether supplementation of these nutrients might represent a therapeutic option for AA...
May 15, 2017: American Journal of Clinical Dermatology
https://www.readbyqxmd.com/read/28487843/anaphylaxis-following-intralesional-triamcinolone-acetonide-kenacort-injection
#2
Wannada Laisuan, Chamard Wongsa, Nizchapha Dchapaphapeaktak, Malinee Tongdee, Jidapa Chatmapanrangsee, Ticha Rerkpattanapipat
Intralesional triamcinolone acetonide injection is indicated for multiple skin conditions such as keloid scars, alopecia areata, and hypertrophic lichen planus. Immediate hypersensitivity reaction remains uncommon. We report on a 24-year-old woman who had received multiple intralesional injections with triamcinolone acetonide (Kenacort) plus lidocaine for keloid scar treatment without any reaction for the previous 10 years. The immediate reaction occurred 15 minutes after injection, with numbness on her face and 5 minutes later with urticaria on her chest wall and upper extremities, together with hypotension (blood pressure of 90/60 mmHg)...
April 2017: Asia Pacific Allergy
https://www.readbyqxmd.com/read/28462859/exfoliative-erythroderma-and-palmoplantar-hyperkeratosis-associated-with-majocchi-s-granuloma-by-trichophyton-tonsurans-in-a-patient-with-aids
#3
Marcelo R Lyra, Bruna Muniz Álvarez, Andrea L Lanziano, Maria Auxiliadora A Imbeth, Adriana M Sá, Tullia Cuzzi, Jeferson C Oliveira, Armando O Schubach
BACKGROUND: Dermatophytoses are skin superficial mycoses in which clinical manifestations are directly related to the virulence of the infecting microorganism or the host immunity. CASE REPORT: We describe a severe case of dermatophytosis associated with exfoliative erythroderma, substantial palmoplantar keratoderma, onychodystrophy affecting all nails, diffuse non-scarring alopecia and tissue fungal invasion by Trichophyton tonsurans, which led us to the diagnosis of AIDS...
April 24, 2017: Revista Iberoamericana de Micología
https://www.readbyqxmd.com/read/28442883/a-comment-on-frontal-fibrosing-alopecia-axel-munthe-s-syndrome
#4
Ralph M Trüeb
Frontal fibrosing alopecia (FFA) represents a peculiar condition with a quasi-symmetrical, marginal alopecia along the frontal and temporal hairline with scarring. Steven Kossard is credited with the original description of the condition in 1994. Since its first description, FFA has become increasingly common while its etiology has remained obscure. While FFA has been related to lichen planopilaris, in fact, the pattern of clinical disease presentation might be more specific for the condition than the underlying inflammatory autoimmune reaction...
October 2016: International Journal of Trichology
https://www.readbyqxmd.com/read/28442882/comparative-analysis-of-immunopathological-features-of-lichen-planopilaris-and-female-patients-with-frontal-fibrosing-alopecia
#5
Emanuella Rd Cerqueira, Neusa Valente, Mírian Nacagami Sotto, Ricardo Romiti
BACKGROUND: Frontal fibrosing alopecia (FFA) is a disorder characterized by progressive cicatricial alopecia (CA). Its classification as a clinical variant of lichen planopilaris (LPP) or as a unique disorder is controversial. The presence of Langerhans cells within the bulge area and the sebaceous epithelium and the presence of lymphocytic infiltrate in this area in CA have led to a series of hypotheses, although limited, about their development. To our knowledge, scarce is the literature demonstrating immunoanalytical studies comparing both disorders...
October 2016: International Journal of Trichology
https://www.readbyqxmd.com/read/28437267/reconstruction-of-pediatric-scalp-avulsion-injuries-after-dog-bites
#6
Zhi Yang Ng, Kyle R Eberlin, Tianyu Lin, Peter T Masiakos, Curtis L Cetrulo
Dog bite injuries are common and the head and neck is most frequently involved in pediatric patients. In severe cases, the combination of crushing, tearing, and puncturing can result in scalp avulsion. Currently, microsurgical replantation of the avulsed scalp remains the gold standard but may not always be possible. The authors present their treatment algorithm with 2 patient examples. In Patient 1, the scalp was deemed unsuitable for replantation due to extensive soft tissue injury; in Patient 2, the scalp was not available on presentation...
April 21, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28426907/frontal-fibrosing-alopecia-clinical-and-prognostic-classification
#7
O M Moreno-Arrones, D Saceda-Corralo, P Fonda-Pascual, A R Rodrigues-Barata, D Buendía-Castaño, A Alegre-Sánchez, C Pindado-Ortega, M Molins, D Perosanz, G Segurado-Miravalles, P Jaén, S Vañó-Galván
BACKGROUND: Frontal fibrosing alopecia (FFA) is a chronic scarring alopecia with an unpredictable evolution. There are no current classifications of this disease that may predict its prognosis. OBJECTIVE: To analyze the differences in clinical presentation and evolution of FFA patients and to create a clinical and prognostic classification METHODS: We conducted a retrospective analytical study of FFA patients. Clinical characteristics of frontal hairline recession were used as the sorting variable between patterns of presentation...
April 20, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28405548/clinicoepidemiological-and-mycological-study-of-tinea-capitis-in-the-pediatric-population-of-kashmir-valley-a-study-from-a-tertiary-care-centre
#8
Yasmeen J Bhat, Sumaya Zeerak, Farhat Kanth, Atiya Yaseen, Iffat Hassan, Rubina Hakak
BACKGROUND: Tinea capitis is a superficial fungal infection that predominantly affects the pediatric population. The etiological factors vary from region to region, and the exact incidence remains obscure. The clinicoepidemiological and mycological aspects of this dermatophytosis were studied in a tertiary care centre in Kashmir valley. AIM: To determine the clinicoepidemiological aspects and mycological findings of dermatophytes involved in tinea capitis cases in Kashmir valley...
March 2017: Indian Dermatology Online Journal
https://www.readbyqxmd.com/read/28403264/a-retrospective-review-of-treatment-results-for-patients-with-central-centrifugal-cicatrical-alopecia
#9
Ariana Eginli, Emily Dothard, Courtney W Bagayoko, Karen Huang, Alyssa Daniel, Amy J McMichael
<p>INTRODUCTION: Central centrifugal cicatricial alopecia (CCCA) is a form of scarring alopecia primarily affecting women of African descent on the crown of the scalp. Limited data exists regarding evidence-based treatment for CCCA.</p> <p>OBJECTIVE: To examine photos of subjects with CCCA before and after treatment in order to evaluate results of treatment and compare results of different treatment regimens.</p> <p>METHODS: Photographs of 15 subjects with CCCA before and after treatment were evaluated by two blinded investigators who assigned disease severity scores to photographs based on a published scale: Central Scalp Alopecia Photographic Scale in African American Women...
April 1, 2017: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/28403263/microneedling-in-all-skin-types-a-review
#10
Lauren Meshkov Bonati, Gorana Kuka Epstein, Tamara Lazic Strugar
<p>INTRODUCTION: Microneedling procedures are growing in popularity for a wide variety of skin conditions. This paper comprehensively reviews the medical literature regarding skin needling efficacy and safety in all skin types and in multiple dermatologic conditions.</p> <p>METHODS: A PubMed literature search was conducted in all languages without restriction and bibliographies of relevant articles reviewed. Search terms included: "microneedling," "percutaneous collagen induction," "needling," "skin needling," and "dermaroller...
April 1, 2017: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/28400347/squiz-your-knowledge-expanding-scarring-alopecia-in-a-patient-with-porphyria-cutanea-tarda
#11
Sara Campos, André Lencastre
No abstract text is available yet for this article.
April 1, 2017: European Journal of Dermatology: EJD
https://www.readbyqxmd.com/read/28384669/dermatologic-features-of-classic-movie-villains-the-face-of-evil
#12
Julie Amthor Croley, Vail Reese, Richard F Wagner
Importance: Dichotomous dermatologic depictions of heroes and villains in movies have been used since the silent film age. Objective: To evaluate the hero-villain skin dichotomy in film by (1) identifying dermatologic findings of the all-time top 10 American film villains, (2) comparing these dermatologic findings to the all-time top 10 American film heroes quantitatively and qualitatively, and (3) analyzing dermatologic portrayals of film villains in depth. Design, Setting, and Participants: In this cross-sectional study, dermatologic findings for film heroes and villains in mainstream media were identified and compared quantitatively using a χ2 test with α < ...
April 5, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/28329583/dermatologic-care-of-the-transgender-patient
#13
Timothy Hermosura Almazan, Filamer D Kabigting
Literature is limited regarding the medical and cosmetic dermatologic issues pertinent to transgender patients and the reasons why 19 transgender individuals seek care from dermatologists. Clinical management of this population has historically been limited to 20 mental health providers, endocrinologists, and select surgeons with expertise in sex reassignment surgery. The impact of hormonal 21 therapy on transgender skin has been well documented in endocrinology journals, but is underrepresented in dermatology 22 literature...
October 15, 2016: Dermatology Online Journal
https://www.readbyqxmd.com/read/28329577/two-cases-of-halo-scalp-ring
#14
Thaer Hasan Douri
Halo scalp ring (HSR) is a rare form of non-scarring annular alopecia that is attributed to caput succedaneum. It arises perinatally because of prolonged pressure on the scalp by the cervix during or before the delivery. We report two new cases of halo scalp ring in full term pregnancy - newborns.
November 15, 2016: Dermatology Online Journal
https://www.readbyqxmd.com/read/28329549/frontal-fibrosing-alopecia-in-a-46-year-old-man
#15
Forrest White, Shields Callahan, Randie H Kim, Shane A Meehan, Jennifer Stein
Frontal fibrosing alopecia is a scarring alopecia thatis characterized by recession of the frontotemporalhairline with the frequent loss of eyebrows. Itpredominantly affects postmenopausal womenand only rarely affects men. We report the caseof a 46-year-old man with a ten-year history of anerythematous patch with perifollicular erythemaat the superior aspect of the forehead andfrontotemporal hairline. A skin biopsy specimenshowed a perivascular, lymphocytic infiltrate withperiinfundibular fibrosis. These findings establisheda diagnosis of frontal fibrosing alopecia...
December 15, 2016: Dermatology Online Journal
https://www.readbyqxmd.com/read/28326731/-complications-of-supratemporalis-approach-with-scalp-coronal-incision-for-orbital-zygomatic-fracture
#16
Wang Yanan, Huang Yanli, Dilnur Dilxat, Liu Weilong, Li Hui, Wang Yi, Liu Lei
OBJECTIVE: This study aimed to examine the complications of supratemporalis approach with scalp coronal incision for the treatment of orbital-zygomatic fractures. METHODS: A total of 206 patients with orbital-zygomatic fractures were treated with scalp coronal incision through the supratemporalis approach. The effects and complications of the treatment were analyzed. RESULTS: The degree of fracture of the 206 patients was successfully reduced...
February 1, 2017: Hua Xi Kou Qiang Yi Xue za Zhi, Huaxi Kouqiang Yixue Zazhi, West China Journal of Stomatology
https://www.readbyqxmd.com/read/28318040/clinical-and-laboratory-characteristics-of-a-tinea-capitis-outbreak-among-novice-buddhist-monks
#17
Sumanas Bunyaratavej, Charussri Leeyaphan, Chuda Rujitharanawong, Chanai Muanprasat, Lalita Matthapan
Sixty novice Buddhist monks with tinea capitis confirmed according to clinical presentation and mycological laboratory finding were included in this study. Mixed-type clinical presentation was observed in approximately half of all cases, together with scarring alopecia (95%) and superficial fungal skin infection at locations other than the scalp (43.3%). The major isolated organism was Trichophyton violaceum, and mixed-organism infection was found in 27 cases (45%). Slow-onset presentation and an extensive area of infection were significantly associated with mixed-type clinical presentation...
March 20, 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/28300891/lichen-planopilaris-like-eruption-during-treatment-with-tyrosine-kinase-inhibitor-nilotinib
#18
Juliana Ribeiro Leitão, Neusa Yuriko Sakai Valente, Priscila Kakizaki, Isis Suga Veronez, Mario Cezar Pires
Tyrosine kinase inhibitors are effective as a target therapy for malignant neoplasms. Imatinib was the first tyrosine kinase inhibitor used. After its introduction, several other drugs have appeared with a similar mechanism of action, but less prone to causing resistance. Even though these drugs are selective, their toxicity does not exclusively target cancer cells, and skin toxicity is the most common non-hematologic adverse effect. We report an eruption similar to lichen planopilaris that developed during therapy with nilotinib, a second generation tyrosine kinase inhibitor, in a patient with chronic myeloid leukemia resistant to imatinib...
September 2016: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/28300881/frontal-fibrosing-alopecia-in-association-with-sj%C3%A3-gren-s-syndrome-more-than-a-simple-coincidence
#19
Karina Colossi Furlan, Priscila Kakizaki, Juliana Cabral Nunes Chartuni, Neusa Yuriko Sakai Valente
Frontal fibrosing alopecia is a distinctive form of scarring alopecia considered to be a clinical variant of lichen planopilaris. It predominantly occurs in postmenopausal women and has a slowly progressive course. It was first described by Kossard in 1994. Since then the number of reported cases has increased significantly. Coexistence of frontal fibrosing alopecia and autoimmune disorders - such as discoid erythematosus lupus and Sjögren's syndrome - may suggest a common pathogenic background among the diseases...
September 2016: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/28300084/alopecia-areata
#20
REVIEW
C Herbert Pratt, Lloyd E King, Andrew G Messenger, Angela M Christiano, John P Sundberg
Alopecia areata is an autoimmune disorder characterized by transient, non-scarring hair loss and preservation of the hair follicle. Hair loss can take many forms ranging from loss in well-defined patches to diffuse or total hair loss, which can affect all hair-bearing sites. Patchy alopecia areata affecting the scalp is the most common type. Alopecia areata affects nearly 2% of the general population at some point during their lifetime. Skin biopsies of affected skin show a lymphocytic infiltrate in and around the bulb or the lower part of the hair follicle in the anagen (hair growth) phase...
March 16, 2017: Nature Reviews. Disease Primers
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