Naoto Azuma, Masaru Natsuaki, Naoaki Hashimoto, Takeo Abe, Suzu Ueda, Yuko Ohno, Masatoshi Jinnin, Kiyoshi Matsui
Alopecia associated with lupus erythematosus is broadly classified into reversible nonscarring alopecia seen in the acute phase, such as worsening of systemic lupus erythematosus (SLE) and cicatricial alopecia seen in chronic cutaneous lupus erythematosus represented by discoid lupus erythematosus (DLE). In DLE-induced alopecia, early therapeutic intervention before developing scarring alopecia is important, but the condition is often resistant to conventional treatment. Anifrolumab (ANI), a novel therapeutic agent for SLE that inhibits type I interferon activity, has been shown to be effective against acute skin lesions, including alopecia, in patients with SLE...
April 10, 2024: Modern rheumatology case reports