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hyaluronic acid filler

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https://www.readbyqxmd.com/read/29788065/commentary-on-the-risk-of-skin-necrosis-following-hyaluronic-acid-filler-injection-in-patients-with-a-history-of-cosmetic-rhinoplasty
#1
Claudio DeLorenzi
No abstract text is available yet for this article.
May 18, 2018: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/29761211/comparative-study-of-uma-jeunesse-classic-%C3%A2-and-uma-jeunesse-ultra-%C3%A2
#2
Peeyush P Sharma, Dave Krishan Sharma, Andrew Carr
INTRODUCTION: The emergence of hyaluronic acid dermal fillers with lidocaine has transformed the minimally invasive treatment of wrinkles, lines and folds of the face. Patients can be treated quickly, painlessly and without the need for large doses of lidocaine. Therefore, it is important to scientifically evaluate the merits of lidocaine-containing products over those without. METHODS: The two products, with (UJU) and without lidocaine (UJ), were randomly injected into nasolabial folds of 75 healthy volunteers with varying skin types in a split face study, age ranging 26-60 years...
May 14, 2018: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/29750757/the-role-of-anastomotic-vessels-in-controlling-tissue-viability-and-defining-tissue-necrosis-with-special-reference-to-complications-following-injection-of-hyaluronic-acid-fillers
#3
Mark W Ashton, G Ian Taylor, Russell J Corlett
BACKGROUND: Most target areas for facial volumization procedures relate to the anatomical location of the facial or ophthalmic artery. Occasionally, inadvertent injection of hyaluronic acid (HA) filler into the arterial circulation occurs, and unrecognised, is irreparably associated with disastrous vascular complications.Of note, the site of complications, irrespective of the injection site, is similar, and falls into only 5 areas of the face, all within the functional angiosome of the facial or ophthalmic artery...
March 15, 2018: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29742193/nodule-formation-following-treatment-with-hyaluronic-acid-fillers-a-report-of-two-challenging-cases
#4
Meredith L Orseth, Nicole Lee, Omer Ibrahim, Kenneth A Arndt, Michael Kaminer
Nodule formation can be a potentially disfiguring adverse event of soft tissue fillers. Limited treatment consensus exists regarding the optimal approach for addressing recurrent and persistent nodules. Here we describe two challenging cases of nodules that developed following injection with Restylane and Juvéderm Voluma. We review suspected pathophysiology and discuss our treatment approach. J Drugs Dermatol. 2018;17(5):580-581.
May 1, 2018: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/29742187/degradation-of-hylauronic-acid-fillers-using-hyaluronidase-in-an-in-vivo-model
#5
Rodrigo Moraes Ferraz, Ulrika Sandkvist, Björn Lundgren
INTRODUCTION: Soft tissue fillers manufactured with hyaluronic acid (HA) dominate the filler market around the world and the fact that HA can be dissolved using hyaluronidase contributes to its popularity. Degradation of cross-linked HA products can be performed in situ and access to hyaluronidase is therefore essential for health care professionals (HCP) to perform safe filler treatments. The aim of the present study was to develop an in vivo model where hyaluronidase degradation of HA fillers can be studied in a standardized manner and then secondly, to explore the degradation of marketed HA fillers with different product characteristics...
May 1, 2018: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/29740661/effectiveness-and-safety-of-hyaluronic-acid-gel-with-lidocaine-for-the-treatment-of-nasolabial-folds-a-systematic-review-and-meta-analysis
#6
REVIEW
Chenglong Wang, Sisi Luan, Adriana C Panayi, Minqiang Xin, Bobin Mi, Jie Luan
BACKGROUND: Hyaluronic acid (HA) gel is a widely used dermal filler for the correction facial volume loss. The incorporation of lidocaine with HA provides a pain-relieving alternative for individuals considering facial rejuvenation. The aim of this systematic review and meta-analysis is to compare the effectiveness and safety of HA with lidocaine (HAL) with that of HA without lidocaine for the treatment of nasolabial folds (NLFs). METHODS: Studies were identified using the electronic databases PubMed, Embase, Cochrane Central Register of Controlled Trials and Web of Science from inception up to January 2018...
May 8, 2018: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/29733533/hyaluronic-acid-dermal-fillers-in-the-management-of-recurrent-angular-cheilitis-a-case-report
#7
Alejandro Ismael Lorenzo-Pouso, Abel García-García, Mario Pérez-Sayáns
OBJECTIVE: To report conservative treatment based on the use of dermal fillers for a case of recurrent angular cheilitis. CASE REPORT: An 80-year-old patient with a history of recurrent angular cheilitis that was not resolved with a conventional approach sought treatment. Complete remission of the pathology was achieved with the injection of hyaluronic acid fillers. CONCLUSION: This case illustrates the potential of nonsurgical facial aesthetics (NSFA) for treating this common pathology among elderly people...
June 2018: Gerodontology
https://www.readbyqxmd.com/read/29710212/effectiveness-of-low-doses-of-hyaluronidase-to-remove-hyaluronic-acid-filler-nodules-a-randomized-clinical-trial
#8
Murad Alam, Rosemara Hughart, Amelia Geisler, Kapila Paghdal, Amanda Maisel, Alexandra Weil, Dennis P West, Emir Veledar, Emily Poon
Importance: Although hyaluronidase is known to remove hyaluronic acid fillers, use of low doses has not been well studied. Objective: To assess the effectiveness and dose-related effect of small quantities of hyaluronidase to treat hyaluronic acid filler nodules. Design, Setting, and Participants: Split-arm, parallel-group, randomized clinical trial at an urban academic center. Participants were 9 healthy women. Recruitment and follow-up occurred from February 2013 to March 2014; data analysis occurred from February to July 2016...
April 25, 2018: JAMA Dermatology
https://www.readbyqxmd.com/read/29701621/safety-and-effectiveness-of-the-hyaluronic-acid-dermal-filler-vyc-17-5l-for-nasolabial-folds-results-of-a-randomized-controlled-study
#9
Gary Monheit, Kenneth Beer, Bhushan Hardas, Pearl E Grimes, Barry M Weichman, Vince Lin, Diane K Murphy
BACKGROUND: Juvéderm Vollure XC (VYC-17.5L) belongs to a family of nonanimal hyaluronic acid (HA) gels based on the Vycross technology platform. OBJECTIVE: To evaluate the safety and effectiveness of VYC-17.5L for correction of moderate to severe nasolabial folds (NLFs) compared with a control HA dermal filler. METHODS: In this double-blind study, 123 adults with 2 moderate or severe NLFs as measured on the 5-point photonumeric NLF severity scale (NLFSS) were randomized to VYC-17...
May 2018: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/29687569/physical-properties-of-a-novel-small-particle-hyaluronic-acid-filler-in-vitro-in-vivo-and-clinical-studies
#10
Sung Yeon Cho, June Whan Park, Hyoseok An, Hyun Ju Ko, Hyuk Kim, Jin Kyu Choi, Sun Young Choi, Sung Min Kim, Eun Jung Ko, Beom Joon Kim
BACKGROUND: Infraorbital region is one of the most important regions that show the signs of aging. In recent years, hyaluronic acid (HA) fillers have been used to correct this region for esthetic treatments. Although HA fillers with various physical properties are used, limited research has been performed to compare their efficacy. OBJECTIVE: We aimed to compare three HA fillers to determine which is the most appropriate filler for the correction of the infraorbital region and evaluate the correction of such by performing a clinical test using CLEVIEL Fine...
April 23, 2018: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/29670737/oral-foreign-body-granuloma-to-soft-tissue-fillers-report-of-two-cases-and-review-of-the-literature
#11
Paris Tamiolakis, Evangelia Piperi, Panagiotis Christopoulos, Alexandra Sklavounou-Andrikopoulou
The increasing demand for cosmetic procedures in the orofacial area nowadays, results in a growing number of complications attributable to soft tissue fillers, including the development of foreign body granuloma. The purpose of this study is to present two additional cases of oral foreign body granulomas caused by liquid silicone and hyaluronic acid respectively and review the pertinent literature regarding the demographics, the clinical appearance, the histopathology and the treatment of these lesions. Key words: Oral foreign body granuloma, hyaluronic acid, silicone, soft tissue filler...
February 2018: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/29659410/in-vivo-degradation-of-crosslinked-hyaluronic-acid-fillers-by-exogenous-hyaluronidases
#12
Garrett T Shumate, Rajesh Chopra, Derek Jones, Darin J Messina, Christopher K Hee
BACKGROUND: An advantage of hyaluronic acid (HA)-based fillers is reversibility. OBJECTIVE: To evaluate the ability of 2 hyaluronidases to degrade 3 HA-based fillers using a novel in vivo model. MATERIALS AND METHODS: Rats were injected with 3 HA fillers (HYC-24L+, VYC-20L, and RES-L) to create a projecting bolus. After 4 days, recombinant human hyaluronidase (HX) or ovine hyaluronidase (VIT) was administered at (1) varying doses (5 U, 10 U, or 30 U per 0...
April 13, 2018: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/29621374/novel-use-of-a-volumizing-hyaluronic-acid-filler-for-treatment-of-infraorbital-hollows
#13
Michael B Hall, Sudeep Roy, Edward D Buckingham
Importance: Hyaluronic acid filler can be safely used as a soft-tissue filler for correction of infraorbital hollowing. It has a high overall patient satisfaction profile among patients. Objective: To report safety and patient satisfaction outcomes of Juvéderm Voluma XC for correction of infraorbital hollows. Design, Setting, and Patients: This was a retrospective observational study performed at a private ambulatory facial plastic and reconstructive surgery practice...
April 5, 2018: JAMA Facial Plastic Surgery
https://www.readbyqxmd.com/read/29616162/successfully-managing-impending-skin-necrosis-following-hyaluronic-acid-filler-injection-using-high-dose-pulsed-hyaluronidase
#14
Kwok Thye David Loh, Yi Shan Phoon, Vanessa Phua, Krishan Mohan Kapoor
Facial fillers are becoming increasingly popular as aesthetic procedures to temporarily reduce the depth of wrinkles or to contour faces. However, even in the hands of very experienced injectors, there is always a small possibility of vascular complications like intra-arterial injection of filler substance. We present a case report of a patient who developed features of vascular obstruction in right infraorbital artery and tell-tale signs of impending skin necrosis, after hyaluronic acid filler injection by an experienced injector...
February 2018: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/29609436/forehead-reconstruction-using-modified-double-opposing-rotation-advancement-flaps-for-severe-skin-necrosis-after-filler-injection
#15
Jinwoo Kim, Woosuk Hwang
Varying degrees of complications can occur after hyaluronic acid filler injections. Tissue necrosis due to interruption of the vascular supply is an early complication that can be severe. If the site of tissue necrosis due to the filler injection is the forehead, successfully reconstructing the region without distorting the key landmarks is challenging. We describe the case of a 50-year-old man who experienced widespread forehead skin necrosis after hyaluronic acid filler injection in the glabellar area. We successfully covered the forehead area with a 3×4-cm2 midline necrotic tissue using the modified double-opposing rotation-advancement flap method...
March 2018: Archives of Craniofacial Surgery
https://www.readbyqxmd.com/read/29607622/ischemic-oculomotor-nerve-palsy-due-to-hyaluronic-acid-filler-injection
#16
In Ho Bae, Min Sung Kim, Hoon Choi, Chan Ho Na, Bong Seok Shin
Hyaluronic acid (HA) is the most popular agent today for intradermal injections to improve wrinkles and other cosmetic defects. Ischemic necrosis due to injection of HA is one of the serious complications. Because there are many vascular branches around the nose, caution and care should be given during facial filler injection. Although the incidence is rare, blindness and permanent visual loss may occur. We describe a 29-year-old woman presented with painful erythematous swelling with violaceous patch on right periocular area and glabella after HA filler injection...
April 1, 2018: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/29601621/prospective-randomized-investigator-blinded-split-face-evaluation-of-a-topical-crosslinked-hyaluronic-acid-serum-for-post-procedural-improvement-of-skin-quality-and-biomechanical-attributes
#17
Hema Sundaram, Angnieszka Cegielska, Agnieszka Wojciechowska, Patrice Delobel
BACKGROUND: This split-face, controlled study investigated the ability of a topical crosslinked hyaluronic acid formulation (RHA serum) to enhance clinical results from fillers, microneedling, or chemical peeling of aging skin. Previous comparative skin explant studies demonstrated greater efficacy of RHA serum than topical non-crosslinked high or low molecular weight hyaluronic acid in decreasing trans-epidermal water loss, increasing epidermal hydration, and improving corneocyte microstructure...
April 1, 2018: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/29552274/eyebrow-contouring-with-hyaluronic-acid-gel-filler-injections
#18
Hamzah Mustak, Danica Fiaschetti, Adit Gupta, Robert Goldberg
Background: The eyebrow region presents challenges for filling: the skin is thick, the three-dimensional anatomy is complex and there is a predisposition towards fat atrophy and skeletonization with aging. Hyaluronic acid gel fillers are well known for their use in the periorbital region. We report our long-term experience with eyebrow filling over a period of five years. Methods: Twenty cases of periorbital eyebrow filling with hyaluronic acid gel fillers were followed up over a period of five years. The eyebrow filling was customized based on the patient's anatomical features in a three-dimensional plane...
February 2018: Journal of Clinical and Aesthetic Dermatology
https://www.readbyqxmd.com/read/29547471/orbital-and-ocular-ischemic-syndrome-with-blindness-after-facial-filler-injection
#19
Sathyadeepak Ramesh, Danica Fiaschetti, Robert A Goldberg
The authors herein describe a case of orbital and ocular ischemic syndrome with blindness after cosmetic hyaluronic acid filler injection. Orbital function, but not visual function, returned after treatment with orbital hyaluronidase and corticosteroids.
March 14, 2018: Ophthalmic Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29543617/randomized-patient-evaluator-blinded-intraindividual-comparison-study-to-evaluate-the-efficacy-and-safety-of-a-novel-hyaluronic-acid-dermal-filler-in-the-treatment-of-nasolabial-folds
#20
RANDOMIZED CONTROLLED TRIAL
Ji Yeon Hong, Eun Ja Choi, Sun Young Choi, Kapsok Li, Beom Joon Kim
BACKGROUND: Comparative research on the characteristics of filler products is limited, especially in the preclinical analysis of hyaluronic acid (HA) fillers. OBJECTIVE: This study was performed to compare the preclinical characteristics, clinical efficacy, and safety of a new HA filler, IDHF-001, with Restylane SubQ in the treatment of nasolabial folds (NLFs). METHODS: Viscoelasticity and injection force were evaluated. Ninety-one subjects were enrolled in this randomized, patient/evaluator-blind, intraindividual clinical study...
April 2018: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
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