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hyaluronic acid filler

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https://www.readbyqxmd.com/read/27911109/confocal-microscopy-and-imaging-profilometry-a-new-tool-aimed-to-evaluate-aesthetic-procedures
#1
Gabriella Fabbrocini, Caterina Mazzella, Fabio Montagnaro, Maria Pia De Padova, Sandra Lorenzi, Aurora Tedeschi, Patrizia Forgione, Claudia Capasso, Luigi Sivero, Carla Velotti, Daniela Russo, Rosa Vitiello, Gennaro Ilardi
According to the American Academy of Aesthetic Plastic Surgeons, more than 11 million cosmetic surgical and nonsurgical procedures were performed by board-certified plastic surgeons, dermatologists and otolaryngologists in the United States, totaling more than 12 billion dollars. We performed a retrospective observational multi-centric study on patients treated with a non-animal origin cross-linked hyaluronic acid with different molecular weights for nasolabial folds, evaluating through a new imaging system, profilometric techniques with the confocal microscopy, the durability, the efficacy and the safety of this product...
December 2, 2016: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/27906442/the-role-of-fillers-in-aesthetic-medicine-medico-legal-aspects
#2
E Marinelli, G Montanari Vergallo, G Reale, A di Luca, I Catarinozzi, S Napoletano, S Zaami
In recent years there has been an exponential increase of fillers use in aesthetic medicine. The popularity of this anti-wrinkle product is based on their capacity to offer significant improvement in the aesthetic field, particularly to skin rejuvenating processes with non-invasive and less expensive techniques, if compared to the surgical methods (i.e. surgical lifting). The great number of fillers on the market is composed of a large heterogenic number of biomaterials. The aim of this review was to provide an overview and a classification of the filling materials that are most commonly used...
November 2016: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/27875939/injectable-shape-memorizing-3d-hyaluronic-acid-cryogels-3d-ma-ha-for-skin-sculpting-and-soft-tissue-reconstruction
#3
Liying Cheng, Kai Ji, Ting-Yu Shih, Anthony Haddad, Giorgio Giatsidis, David J Mooney, Dennis P Orgill, Christoph S Nabzdyk
Introduction Hyaluronic acid based (HA) fillers are used for various cosmetic procedures. However, due to filler migration and degradation, reinjections of the fillers are often required. Methacrylated HA (MA-HA) can be made into injectable, shape-memorizing fillers (3D MA-HA) aimed to address this issue. In this study shape retention, firmness and biocompatibility of 3D MA-HA injected subcutaneously in mice were evaluated. Methods Fifteen mice, each receiving two subcutaneous injections in their back, were divided into 4 groups receiving HA, MA-HA, 3D MA-HA or saline, respectively...
November 22, 2016: Tissue Engineering. Part A
https://www.readbyqxmd.com/read/27860429/antibacterial-nanocomposite-bone-filler-based-on-silver-nanoparticles-and-polysaccharides
#4
Davide Porrelli, Andrea Travan, Turco Gianluca, Matteo Crosera, Borgogna Massimiliano, Ivan Donati, Sergio Paoletti, Gianpiero Adami, Eleonora Marsich
Injectable bone fillers represent an attractive strategy for the treatment of bone defects. These injectable materials should be biocompatible, capable of supporting cell growth and possibly able to exert antibacterial effects. In this work, nanocomposite microbeads based on alginate, chitlac, hydroxyapatite and silver nanoparticles were prepared and characterized. The dried microbeads displayed a rapid swelling in contact with simulated body fluid and maintained their integrity for more than 30 days. The evaluation of silver leakage from the microbeads showed that the antibacterial metal is slowly released in saline solution, with less than 6% of silver released after 1 week...
November 15, 2016: Journal of Tissue Engineering and Regenerative Medicine
https://www.readbyqxmd.com/read/27806168/safety-and-efficacy-of-a-volumizing-hyaluronic-acid-filler-for-treatment-of-hiv-associated-facial-lipoatrophy
#5
Derek Ho, Jared Jagdeo
Importance: Facial lipoatrophy (FLA) is associated with human immunodeficiency virus (HIV) disease and the use of highly active antiretroviral therapy. The condition is primarily characterized by facial volume loss that affects the contours of the cheeks, temples, and orbits and may negatively affect patients' adherence to highly active antiretroviral therapy, psychological health, and quality of life. A single treatment of hyaluronic acid (HA) filler, 20 mg/mL, may provide an immediate, natural-appearing facial enhancement outcome...
November 2, 2016: JAMA Dermatology
https://www.readbyqxmd.com/read/27799807/safety-and-performance-of-cohesive-polydensified-matrix-hyaluronic-acid-fillers-with-lidocaine-in-the-clinical-setting-an-open-label-multicenter-study
#6
Ulrich Kühne, Jørgen Esmann, Dennis von Heimburg, Matthias Imhof, Petra Weissenberger, Gerhard Sattler
Cohesive polydensified matrix (CPM(®)) hyaluronic acid fillers are now available with or without lidocaine. The aim of this study was to investigate the safety and performance of CPM(®) fillers with lidocaine in the clinical setting. In an open-label, prospective, postmarketing study, 108 patients from seven sites in Germany and Denmark were treated with one or more lidocaine-containing CPM(®) fillers. Performance was assessed using the Merz Aesthetics Scales(®) (MAS). Pain was rated on an 11-point visual analog scale...
2016: Clinical, Cosmetic and Investigational Dermatology
https://www.readbyqxmd.com/read/27768196/correction-of-age-related-midface-volume-loss-with-low-volume-hyaluronic-acid-filler
#7
Monique Vanaman Wilson, Sabrina Guillen Fabi, Ryan Greene
Importance: The pivotal approval trial for a smooth, highly cohesive, viscous, 20-mg/mL hyaluronic acid filler demonstrated sustained aesthetic improvement, with a mean injection volume of 6.65 mL. In daily practice, however, it is not often practical or necessary to use large injection volumes to achieve the desired cosmetic outcome. Objective: To assess the efficacy, longevity, and patient satisfaction associated with correction of age-related midface volume loss using the low volumes of hyaluronic acid filler more commonly used in day-to-day practice...
October 20, 2016: JAMA Facial Plastic Surgery
https://www.readbyqxmd.com/read/27748693/delayed-adverse-subcutaneous-reaction-to-a-new-family-of-hyaluronic-acid-dermal-fillers-with-clinical-ultrasound-and-histologic-correlation
#8
Lidia Pérez-Pérez, Juan García-Gavín, Ximena Wortsman, Ángel Santos-Briz
No abstract text is available yet for this article.
September 28, 2016: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/27746650/a-case-of-the-migration-of-hyaluronic-acid-filler-from-nose-to-forehead-occurring-as-two-sequential-soft-lumps
#9
Soo Yuhl Chae, Kyou Chae Lee, Yong Hyun Jang, Seok-Jong Lee, Do Won Kim, Weon Ju Lee
No abstract text is available yet for this article.
October 2016: Annals of Dermatology
https://www.readbyqxmd.com/read/27673483/an-18-month-follow-up-randomized-comparison-of-effectiveness-and-safety-of-two-hyaluronic-acid-fillers-for-treatment-of-moderate-nasolabial-folds
#10
Berthold Rzany, Christiane Bayerl, Isaac Bodokh, Dominique Boineau, Thomas Dirschka, Catherine Queille-Roussel, Michael Sebastian, Boris Sommer, Carolina Edwartz, Maurizio Podda
BACKGROUND: Hyaluronic acid (HA) filler injection is a popular nonsurgical aesthetic procedure. OBJECTIVE: To compare the effectiveness and safety of 2 hyaluronic acid fillers (HAEC and HARES) for treatment of moderate nasolabial folds (NLFs). MATERIALS AND METHODS: This was an evaluator- and subject-blinded split-face study. HAEC or HARES was randomly assigned to the left or right NLF at baseline. Retreatment was performed after 9 months; follow-up extended to 18 months after baseline (9 months after retreatment)...
September 26, 2016: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/27668925/consensus-recommendations-for-combined-aesthetic-interventions-using-botulinum-toxin-fillers-and-microfocused-ultrasound-in-the-neck-d%C3%A3-colletage-hands-and-other-areas-of-the-body
#11
Sabrina G Fabi, Cheryl Burgess, Alastair Carruthers, Jean Carruthers, Doris Day, Kate Goldie, Martina Kerscher, Andreas Nikolis, Tatjana Pavicic, Nark-Kyoung Rho, Berthold Rzany, Sonja Sattler, Kyle Seo, William Philip Werschler, Gerhard Sattler
BACKGROUND: The popularity of aesthetic procedures in the face has led to greater disparity between treated areas and those that still show evidence of true age. Although many areas of the body often require multiple treatment procedures for optimal rejuvenation, combination therapy for specific areas is not yet well defined. OBJECTIVE: To develop recommendations for the optimal combination and ideal sequence of botulinum toxin (BoNT), hyaluronic acid, calcium hydroxylapatite (CaHA), and microfocused ultrasound with visualization in nonfacial areas across all skin phototypes...
October 2016: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/27660479/hyaluronic-acid-fillers-with-cohesive-polydensified-matrix-for-soft-tissue-augmentation-and-rejuvenation-a-literature-review
#12
REVIEW
Adri D Prasetyo, Welf Prager, Mark G Rubin, Ernesto A Moretti, Andreas Nikolis
BACKGROUND: Cohesive monophasic polydensified fillers show unique viscoelastic properties and variable density of hyaluronic acid, allowing for a homogeneous tissue integration and distribution of the material. OBJECTIVE: The aim of this paper was to review the clinical data regarding the performance, tolerability, and safety of the Belotero(®) fillers for soft-tissue augmentation and rejuvenation. METHODS: A literature search was performed up until May 31, 2015 to identify all relevant articles on Belotero(®) fillers (Basic/Balance, Hydro, Soft, Intense, Volume) and equivalent products (Esthélis(®), Mesolis(®), Fortélis(®), Modélis(®))...
2016: Clinical, Cosmetic and Investigational Dermatology
https://www.readbyqxmd.com/read/27631872/botulinum-toxin%C3%A2-a-and-or-soft-tissue-fillers-for-facial-rehabilitation
#13
Uwe Wollina, Alberto Goldman
Botulinum toxin A and soft tissue fillers are cornerstones of facial rejuvenation procedures. They can also be of benefit in facial rehabilitation. We report on three female patients who were treated with botulinum toxin A and/or hyaluronic acid-based fillers, one after orthognathic surgery, two after Bell's palsy, to correct facial asymmetries and loss of volume to restore facial attractiveness and improve their self-esteem and quality of life. These minimally invasive procedures are safe and effective. However, they need to be repeated for the long-term rehabilitation...
September 15, 2016: Wiener Medizinische Wochenschrift
https://www.readbyqxmd.com/read/27606073/effect-of-molecular-weight-of-hyaluronic-acid-ha-on-viscoelasticity-and-particle-texturing-feel-of-ha-dermal-biphasic-fillers
#14
Cheolbyong Chun, Deuk Yong Lee, Jin-Tae Kim, Mi-Kyung Kwon, Young-Zu Kim, Seok-Soon Kim
BACKGROUND: Hyaluronic acid (HA) dermal biphasic fillers are synthesized for their efficacy in correcting aesthetic defects such as wrinkles, scars and facial contouring defects. The fillers consist of crosslinked HA microspheres suspended in a noncrosslinked HA. To extend the duration of HAs within the dermis and obtain the particle texturing feel, HAs are crosslinked to obtain the suitable mechanical properties. RESULTS: Hyaluronic acid (HA) dermal biphasic fillers are prepared by mixing the crosslinked HA microspheres and the noncrosslinked HAs...
2016: Biomaterials Research
https://www.readbyqxmd.com/read/27605904/tear-trough-deformity-different-types-of-anatomy-and-treatment-options
#15
Jindou Jiang, Xuekun Wang, Rongrong Chen, Xueying Xia, Sai Sun, Kuikui Hu
AIM: To explore the efficacy of tear trough deformity treatment with the use of hyaluronic acid gel or autologous fat for soft tissue augmentation and fat repositioning via arcus marginalis release. MATERIAL AND METHODS: Seventy-eight patients with the tear trough were divided into three groups. Class I has tear trough without bulging orbital fat or excess of the lower eyelid skin. Class II is associated with mild to moderate orbital fat bulging, without excess of the lower eyelid skin...
August 2016: Postȩpy Dermatologii i Alergologii
https://www.readbyqxmd.com/read/27602973/rheological-properties-of-calcium-hydroxylapatite-with-integral-lidocaine
#16
Melissa Meland, Chris Groppi, Z Paul Lorenc
BACKGROUND: Calcium hydroxylapatite with integral lidocaine, CaHA (+), received FDA approval in 2015 and CE mark approval in 2016. This formulation has been associated with significant pain reduction compared to CaHA. In a previous rheometry study, CaHA without lidocaine demonstrated higher viscosity and elasticity when compared with hyaluronic acid fillers. STUDY OBJECTIVE: To compare the rheological properties of CaHA (+) lidocaine to CaHA without lidocaine and to compare the rheological measures of CaHA (+) to 5 cross-linked hyaluronic acid (HA) fillers with integral 0...
September 1, 2016: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/27602971/visual-ultrasonographic-and-microscopic-study-on-hyaluronic-acid-based-gel
#17
Patrick Micheels, Stéphanie Besse, Didier Sarrazin
BACKGROUND: Hyaluronic acid (HA) fillers are commonly used for enhancement of lips, and for softening fine lines and correcting skin depressions. OBJECTIVE: This study sought to investigate whether the Vycross<sup>™</sup> technology used for Volbella<sup>™</sup> gel resulted in a cohesive gel, as documented in our previous studies with three other HA fillers (Restylane<sup>®</sup> NASHA<sup>™</sup> [Q-MED, Uppsala, Sweden], Esthélis<sup>®</sup> Basic CPM™ [Anteis SA, Geneva, Switzerland], and Juvéderm<sup>®</sup> Ultra 3 using Hylacross technology [Allergan, Irvine, CA, USA])...
September 1, 2016: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/27602969/lip-injection-techniques-using-small-particle-hyaluronic-acid-dermal-filler
#18
Annie Chiu, Sabrina Fabi, Steven Dayan, Alessandra Nogueira
The shape and fullness of the lips have a significant role in facial aesthetics and outward appearance. The corrective needs of a patient can range from a subtle enhancement to a complete recontouring including correction of perioral rhytides. A comprehensive understanding of the lower face anatomical features and injection site techniques are foundational information for injectors. Likewise, the choice of filler material contributes to the success of the injection techniques used, and facilitates a safe, effective, and natural appearing outcome...
September 1, 2016: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/27602967/patient-reported-outcomes-from-hiv-facial-lipoatrophy-treatment-with-a-volumizing-hyaluronic-acid-filler-a-prospective-open-label-phase-i-and-ii-study
#19
Derek Ho, Jared Jagdeo
BACKGROUND: Human immunodeficiency virus (HIV) facial lipoatrophy (FLA) is associated with the use of highly active antiretroviral therapy (HAART) and HIV disease. HIV FLA is primarily characterized by midface (cheeks and temples) volume loss, resulting in a "sunken" and aged appearance. Filler agents for treatment of HIV FLA can provide midface volumization and improve quality-of-life (QOL). A 20 mg/ml hyaluronic acid (HA) filler (Juvéderm Voluma® XC, Allergan plc, Irvine, CA) may provide an immediate, natural appearing facial enhancement outcome in one treatment...
September 1, 2016: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/27585294/augmentation-pharyngoplasty-for-treatment-of-velopharyngeal-insufficiency-in-children-results-with-injectable-dextranomer-and-hyaluronic-acid-copolymer
#20
Shelagh A Cofer, Becky Baas, Edythe Strand, Cara C Cockerill
OBJECTIVES/HYPOTHESIS: To evaluate the effectiveness, durability, and safety of a tissue filler (dextranomer and hyaluronic acid copolymer) when injected submucosally in the nasopharynx to treat velopharyngeal insufficiency (VPI) in pediatric patients. STUDY DESIGN: Retrospective case series. METHODS: Charts were reviewed for all patients treated with injectable filler at a tertiary children's center for VPI from April 2010 through September 2013...
September 1, 2016: Laryngoscope
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