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Elizabeth O Johnson, Themis C Kamilaris, Aldo E Calogero, Philip W Gold, George P Chrousos
OBJECTIVE: Previous studies on the effects of altered thyroid function on the secretion and metabolism of adrenocortical hormones suggest a degree of adrenocortical hyperactivity in hyperthyroidism. We have previously shown that experimentally-induced hyperthyroidism is associated with significant alterations in pituitary-adrenal responsiveness to synthetic ovine corticotropin-releasing hormone (oCRH) that are contingent upon the duration of the altered thyroid function. The purpose of this study was to assess the time-dependent effects of hyperthyroidism on the functional integrity of the hypothalamic-pituitary-adrenal (HPA) axis by in vivo stimulation of the hypothalamic CRH neuron and adrenal cortex...
July 2005: European Journal of Endocrinology
Jin Narumoto, Syogo Oka, Hiroshi Shimizu, Michihisa Sumi, Yurinosuke Kitabayashi, Hideki Ueda, Kenji Fukui
Hyperthyroidism is associated with increased psychiatric morbidity. It may alter the clinical course of alcohol withdrawal syndrome. We report a 69 year old man who presented prolonged alcohol withdrawal syndrome associated with hyperthyroidism. Initially, he developed typical alcohol withdrawal syndrome including tremor, disorientation, delirium and visual hallucination of small animals. Thyroid function tests revealed a free triiodothyronine (T3) of 6.1 pg/dl (range, 3.0 to 5.8), a free thyroxine (T4) of 2...
February 2005: Nihon Arukōru Yakubutsu Igakkai Zasshi, Japanese Journal of Alcohol Studies & Drug Dependence
N Takasu, K Yamashiro, Y Ochi, Y Sato, A Nagata, I Komiya, H Yoshimura
There are two types of TSH receptor antibodies (TRAb); thyroid stimulating antibody (TSAb) and TSH-stimulation blocking antibody (TSBAb). TSAb causes Graves' hyperthyroidism. TSBAb causes hypothyroidism. Both TSAb and TSBAb block TSH-binding to thyroid cells as TSH receptor antibodies (TRAb). TSBAb-positive patients with hypothyroidism and Graves' patients with hyperthyroidism may have both TSBAb and TSAb. We studied TSBAb and TSAb in 43 TSBAb-positive patients with hypothyroidism and in 55 untreated Graves' patients with hyperthyroidism...
April 2001: Hormone and Metabolic Research, Hormon- und Stoffwechselforschung, Hormones et Métabolisme
I Ono, S Saito, T Sakurada, M Yamamoto, K Yoshinaga
No abstract text is available yet for this article.
August 1973: Horumon to Rinsho. Clinical Endocrinology
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