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hepatology international

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https://www.readbyqxmd.com/read/28440305/acute-kidney-injury-in-cirrhosis-baseline-serum-creatinine-predicts-patient-outcomes
#1
F Wong, J G O'Leary, K R Reddy, G Garcia-Tsao, M B Fallon, S W Biggins, R M Subramanian, P J Thuluvath, P S Kamath, H Patton, B Maliakkal, P Tandon, H Vargas, L Thacker, J S Bajaj
OBJECTIVES: The International Ascites Club (IAC) recently defined Stage 1 acute kidney injury (AKI) for cirrhosis as an acute increase in serum creatinine (SCr) by ≥0.3 mg/dl or by ≥50% in <48 h from a stable value within 3 months. The baseline SCr may influence AKI risk and patient outcomes. The objective of this study is to determine in cirrhosis whether the baseline SCr has any effect on the in-hospital AKI course and patient survival. METHODS: North American Consortium for the Study of End-Stage Liver Disease is a consortium of tertiary-care hepatology centers prospectively enroling non-elective cirrhotic inpatients...
April 25, 2017: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/28396038/severe-reduction-of-blood-lysosomal-acid-lipase-activity-in-cryptogenic-cirrhosis-a-nationwide-multicentre-cohort-study
#2
Francesco Angelico, Stefano Ginanni Corradini, Daniele Pastori, Silvia Fargion, Anna Ludovica Fracanzani, Mario Angelico, Luigi Bolondi, Giulia Tozzi, Pietro Luigi Pujatti, Giancarlo Labbadia, Gino Roberto Corazza, Maurizio Averna, Francesco Perticone, Giuseppe Croce, Marcello Persico, Tommaso Bucci, Francesco Baratta, Licia Polimeni, Maria Del Ben, Francesco Violi
BACKGROUND AND AIMS: Blood lysosomal acid lipase (LAL) is reduced in non-alcoholic steatohepatitis, which is the major cause of cryptogenic cirrhosis (CC); few data on LAL activity in CC do exist. We investigated LAL activity in a cohort of patients with liver cirrhosis. METHODS: This is a multicentre cohort study including 274 patients with liver cirrhosis of different aetiology from 19 centres of Internal Medicine, Gastroenterology and Hepatology distributed throughout Italy...
March 31, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/28341083/scientific-publications-in-gastroenterology-and-hepatology-in-taiwan-an-analysis-of-web-of-science-from-1993-to-2013
#3
Hsiao-Ting Chang, Ming-Hwai Lin, I-Hsuan Hwang, Tzeng-Ji Chen, Han-Chieh Lin, Ming-Chih Hou, Shinn-Jang Hwang
BACKGROUND: Scientific publications are important for evaluating the achievements of a medical specialty or discipline. Gastroenterology and Hepatology is a medical specialty in great demand in Taiwan, therefore, this study aimed to analyze the Gastroenterology and Hepatology publications from 1993 to 2013 in Taiwan, using the Web of Science (WoS) database. METHODS: Scientific publications from departments/institutes of gastroenterology and hepatology were retrieved and analyzed from the WoS database, which included articles published in the Science Citation Index Expanded and Social Science Citation Index journals from 1993 to 2013...
February 2017: Journal of the Chinese Medical Association: JCMA
https://www.readbyqxmd.com/read/28216189/rotavirus-immunization-global-coverage-and-local-barriers-for-implementation
#4
Andrea Lo Vecchio, Ilaria Liguoro, Jorge Amil Dias, James A Berkley, Chris Boey, Mitchell B Cohen, Sylvia Cruchet, Eduardo Salazar-Lindo, Samir Podder, Bhupinder Sandhu, Philip M Sherman, Toshiaki Shimizu, Alfredo Guarino
BACKGROUND: Rotavirus (RV) is a major agent of gastroenteritis and an important cause of child death worldwide. Immunization (RVI) has been available since 2006, and the Federation of International Societies of Gastroenterology Hepatology and Nutrition (FISPGHAN) identified RVI as a top priority for the control of diarrheal illness. A FISPGHAN working group on acute diarrhea aimed at estimating the current RVI coverage worldwide and identifying barriers to implementation at local level...
February 16, 2017: Vaccine
https://www.readbyqxmd.com/read/28199778/a-national-retrospective-study-of-paediatric-end-stage-liver-disease-as-a-predictor-of-change-to-second-line-therapy-in-children-with-autoimmune-hepatitis
#5
Andréanne N Zizzo, Carolina Jimenez-Rivera, Joseph Kim, Richard A Schreiber, Simon C Ling, Jason Yap, Jeff Critch, Najma Ahmed, Fernando Alvarez, Binita M Kamath
BACKGROUND & AIMS: Adult studies of autoimmune hepatitis (AIH) have shown that the model of end-stage liver disease is associated with resistance to first-line treatment. Using a multicentre retrospective database, we sought to determine if the paediatric end-stage liver disease (PELD) score would similarly predict treatment resistance in paediatric AIH. METHODS: One hundred and seventy-one children from 13 Canadian centres who fulfilled the International Autoimmune Hepatitis Group (IAIHG) criteria were included and assessed for change to second-line therapy within 24 months of primary treatment onset...
February 15, 2017: Liver International: Official Journal of the International Association for the Study of the Liver
https://www.readbyqxmd.com/read/28147426/-spontaneous-bacterial-peritonitis
#6
Ľubomír Skladaný, Silvia Kasová, Anna Purgelová, Natália Bystrianska, Svetlana Adamcová-Selčanová
AIM OF STUDY: Spontaneous bacterial peritonitis (SBP) is the most frequent infectious complication of liver cirrhosis with serious consequences. Initially, SBP is always treated with empirical, not targeted, antibiotic therapy. Since a retrospective study performed in our department showed suboptimal effectiveness (only 40 %) of empirical antibiotic therapy in accordance with the EASL guidelines, a decision was made to change the protocol. The aims of this prospective study were to determine: (1) the incidence and characteristics of SBP in real clinical practice - in a liver unit of a tertiary hospital, (2) the effectiveness of new antibiotic therapy selected based on analysis of the spectrum of pathogens and their resistance to antibiotics as identified in a retrospective cohort study on SBP carried out in our department, (3) mortality, and to compare these findings with the literature data...
December 2016: Klinická Mikrobiologie a Infekc̆ní Lékar̆ství
https://www.readbyqxmd.com/read/28139500/variation-in-inflammatory-bowel-disease-care-among-saudi-pediatric-gastroenterologists
#7
Ahmed A Al-Sarkhy
BACKGROUND/AIM: Although international guidelines in inflammatory bowel disease (IBD) management are currently available, variations in IBD care still exist. The aim of this study was to determine the extent of the variation in IBD care among Saudi pediatric gastroenterologists. MATERIALS AND METHODS: A cross-sectional survey was conducted among all pediatric gastroenterologists who were members of the Saudi Society of Pediatric Gastroenterology, Hepatology, and Nutrition (SASPGHAN) from August 2015 to December 2015...
January 2017: Saudi Journal of Gastroenterology: Official Journal of the Saudi Gastroenterology Association
https://www.readbyqxmd.com/read/28073419/-the-2016-annual-meeting-of-chinese-society-of-hepatology-the-3rd-forum-of-youngth-committee-of-csh-the-6th-conference-of-the-china-indonesia-joint-international-symposium-on-hepatobiliary-medicine-and-surgery-6th-cishms
#8
Z P Duan, Y Chen, S J Zheng, L Zhou, M Liu, H B Shi, L Bai
No abstract text is available yet for this article.
December 20, 2016: Zhonghua Gan Zang Bing za Zhi, Zhonghua Ganzangbing Zazhi, Chinese Journal of Hepatology
https://www.readbyqxmd.com/read/28051785/%C3%A2-celebrating-fifteen-years-of-annals-of-hepatology-publication-the-international-open-access-clinical-journal-devoted-to-liver-diseases
#9
Rolf Teschke, Eric M Yoshida, Nahum Méndez-Sánchez
No abstract text is available yet for this article.
January 2017: Annals of Hepatology
https://www.readbyqxmd.com/read/27860475/-new-diagnostic-imaging-technique-shear-wave-elastography
#10
M Zemanová
Shear wave elastography (SWE) is a new non-invasive diagnostic imaging technique, that maps the elastic properties of tissues. Nowadays this modality develops increasingly in medicine across its disciplines and opens a new era of high-quality ultrasound examination because it increases the specificity and thus improves diagnostic assurance. This method is similar to manual palpation, shows elastic properties of biological tissues and provides a kind of reconstruction of the internal structure of soft tissues based on measurement of the response of tissue compression...
2016: Ceská a Slovenská Oftalmologie
https://www.readbyqxmd.com/read/27829652/pediatric-gastroenterology-in-cuba-evolution-and-challenges
#11
Carlos Castañeda-Guillot
INTRODUCTION The professional practice of pediatric gastroenterology arose in Cuba as an expression of the specialty's development internationally and Cuba's new strategies in public health, and in response to national needs for health care expertise in digestive diseases of infants, older children and adolescents. OBJECTIVES Describe the history of pediatric gastroenterology's development in Cuba since its inception at the National Gastroenterology Institute in the early 1970s, its contributions, and efforts to extend it to pediatric hospitals throughout Cuba...
October 2016: MEDICC Review
https://www.readbyqxmd.com/read/27792252/questionnaire-based-survey-in-a-developing-country-showing-noncompliance-with-paediatric-gastro-oesophageal-reflux-practice-guidelines
#12
Hayat Manasfi, Rima Hanna-Wakim, Imad Akel, Nadine Yazbeck
AIM: This 2015 study investigated whether Lebanese paediatricians diagnosed and managed gastro-oesophageal reflux disease (GERD) in infants and children in accordance with the 2009 guidelines from the North American and European Societies for Paediatric Gastroenterology, Hepatology and Nutrition. METHODS: Paediatricians members of the Lebanese Order of Physicians with updated email addresses were invited to complete a web-based survey between September and November 2015, to assess their knowledge and management of GERD...
February 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/27784430/-prognostic-value-of-a-logistic-regression-model-based-on-keratin-18-in-patients-with-hbv-related-liver-failure
#13
Q R Gan, X Y Jiang, X Zhang, M S Chen, C Pan
Objective: To investigate the association between serum keratin 18 (K18) level and prognosis in patients with HBV-related acute-on-chronic liver failure (ACLF). Methods: A total of 120 patients who visited Department of Hepatology in Fuzhou Infectious Disease Hospital and were diagnosed with HBV-related ACLF from December 2012 to March 2014 were enrolled and followed up for 3 months. The patients were divided into death group and survival group. The serum levels of K18 fragments (M30 and M65) were measured and related laboratory data were collected to analyze the differences in M30, M65, M30/M65, and other laboratory markers...
July 20, 2016: Zhonghua Gan Zang Bing za Zhi, Zhonghua Ganzangbing Zazhi, Chinese Journal of Hepatology
https://www.readbyqxmd.com/read/27610350/significant-variations-in-nutritional-supplementation-amongst-neonates-in-the-united-kingdom
#14
Morris Gordon, Sahira Isaji, Fiona Tyacke
AIM: To ascertain United Kingdom adherence to European society of Paediatric Gastroenterology, Hepatology and Nutrition guidance (ESPGHAN). METHODS: A national cross sectional questionnaire study of neonatal units across England was completed between January and March 2014. All 174 units in the country were attempted to be contacted to complete a telephone survey. This included all level 1, 2 and 3 units. They were initially contacted by phone and asking any senior member of the team about their current practice and procedures...
August 8, 2016: World Journal of Clinical Pediatrics
https://www.readbyqxmd.com/read/27590261/indications-for-liver-transplantation-in-adults-recommendations-of-the-austrian-society-for-gastroenterology-and-hepatology-%C3%A3-ggh-in-cooperation-with-the-austrian-society-for-transplantation-transfusion-and-genetics-atx
#15
Ivo Graziadei, Heinz Zoller, Peter Fickert, Stefan Schneeberger, Armin Finkenstedt, Markus Peck-Radosavljevic, Helmut Müller, Claudia Kohl, Barbara Sperner-Unterweger, Stephan Eschertzhuber, Harald Hofer, Dietmar Öfner, Herbert Tilg, Wolfgang Vogel, Michael Trauner, Gabriela Berlakovich
Liver transplantation has emerged as an established and well-accepted therapeutic option for patients with acute and chronic liver failure and hepatocellular carcinoma. The disproportion between recipients and donors is still an ongoing problem that has only been solved partially over the last centuries. For several patients no life-saving organs can be distributed. Therefore, objective and internationally established recommendations regarding indication and organ allocation are imperative. The aim of this article is to establish evidence-based recommendations regarding the evaluation and assessment of adult candidates for liver transplantation...
October 2016: Wiener Klinische Wochenschrift
https://www.readbyqxmd.com/read/27544545/the-challenges-of-multi-drug-resistance-in-hepatology
#16
REVIEW
Javier Fernández, Frédéric Bert, Marie-Hélène Nicolas-Chanoine
Antimicrobial resistance has become a major global public health security problem that needs coordinated approaches at regional, national and international levels. Antibiotic overuse and the failure of control measures to prevent the spread of resistant bacteria in the healthcare environment have led to an alarming increase in the number of infections caused by resistant bacteria, organisms that resist many (multi-drug and extensively drug-resistant strains), if not all (pan-drug-resistant bacteria) currently available antibiotics...
November 2016: Journal of Hepatology
https://www.readbyqxmd.com/read/27506929/novel-educational-interventions-in-residency-increase-knowledge-of-chronic-liver-disease-and-career-interest-in-hepatology
#17
Adam E Mikolajczyk, Jeanne M Farnan, John F McConville, Donald M Jensen, K Gautham Reddy, Helen S Te, Nancy Reau, Andrew I Aronsohn
There is an increasing burden of chronic liver disease (CLD) in the United States but a significant shortage of hepatologists. Thus, it is necessary to develop new recruitment strategies to the field of hepatology as well as ensure that non-gastroenterology-trained physicians are able to capably assist in the care of CLD. We established a novel, nonelective, inpatient hepatology rotation that uses required modules in the American Association for the Study of Liver Diseases Curriculum and Training-First Hepatitis B and C curriculums as well as in LiverLearning...
December 2016: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
https://www.readbyqxmd.com/read/27246646/-infectious-and-other-somatic-comorbidity-in-problem-drug-users-results-of-a%C3%A2-cross-sectional-study-with-medical-examination
#18
V Mravčík, Z Florián, V Nečas, J Štolfa
BACKGROUND: Problem drug use is associated with excess risk of infectious and other somatic diseases resulting mainly from injecting drug use. MATERIAL AND METHODS: At the end of 2013, a complete medical history and physical examination was done in 40 problem drug users (30 males and 10 females), mean age 35.5 years (37.0 and 30.9, respectively), recruited in 4 low-threshold facilities in Prague. Of them, 37 were ex- or active injecting drug users, predominantly of methamphetamine (pervitin) and less often of buprenorphine...
2016: Epidemiologie, Mikrobiologie, Imunologie
https://www.readbyqxmd.com/read/27226805/hepatitis-monthly-an-international-journal-in-the-field-of-hepatology
#19
Mohammad Saeid Rezaee-Zavareh, Seyed Hassan Sa'adat, Seyed Moayed Alavian
No abstract text is available yet for this article.
March 2016: Hepatitis Monthly
https://www.readbyqxmd.com/read/27122670/influence-of-antibiotic-regimens-on-intensive-care-unit-mortality-and-liver-cirrhosis-as-risk-factor
#20
COMPARATIVE STUDY
Mireen Friedrich-Rust, Beate Wanger, Florian Heupel, Natalie Filmann, Reinhard Brodt, Volkhard Aj Kempf, Johanna Kessel, Thomas A Wichelhaus, Eva Herrmann, Stefan Zeuzem, Joerg Bojunga
AIM: To assess the rate of infection, appropriateness of antimicrobial-therapy and mortality on intensive care unit (ICU). Special focus was drawn on patients with liver cirrhosis. METHODS: The study was approved by the local ethical committee. All patients admitted to the Internal Medicine-ICU between April 1, 2007 and December 31, 2009 were included. Data were extracted retrospectively from all patients using patient charts and electronic documentations on infection, microbiological laboratory reports, diagnosis and therapy...
April 28, 2016: World Journal of Gastroenterology: WJG
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