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https://www.readbyqxmd.com/read/29663553/rapid-evidence-assessment-of-approaches-to-community-neurological-nursing-care-for-people-with-neurological-conditions-post-discharge-from-acute-care-hospital
#1
REVIEW
Judith Dianne Pugh, Kathleen McCoy, Anne M Williams, Brenda Bentley, Leanne Monterosso
Neurological conditions represent leading causes of non-fatal burden of disease that will consume a large proportion of projected healthcare expenditure. Inconsistent access to integrated healthcare and other services for people with long-term neurological conditions stresses acute care services. The purpose of this rapid evidence assessment, conducted February-June 2016, was to review the evidence supporting community neurological nursing approaches for patients with neurological conditions post-discharge from acute care hospitals...
April 16, 2018: Health & Social Care in the Community
https://www.readbyqxmd.com/read/29625094/conceptual-underpinnings-of-the-quality-of-life-in-neurological-disorders-neuro-qol-comparisons-of-core-sets-for-stroke-multiple-sclerosis-spinal-cord-injury-and-traumatic-brain-injury
#2
Alex W K Wong, Stephen C L Lau, Mandy W M Fong, David Cella, Jin-Shei Lai, Allen W Heinemann
OBJECTIVE: To determine the extent to which the content of the Quality of Life in Neurological Disorders (Neuro-QoL) covers the ICF core sets for multiple sclerosis (MS), stroke, spinal cord injury (SCI), and traumatic brain injury (TBI) using summary linkage indicators. DESIGN: Content analysis by linking content of the Neuro-QoL to corresponding ICF codes of each core set for MS, stroke, SCI, and TBI. SETTING: Three academic centers PARTICIPANTS: None INTERVENTIONS: None MAIN OUTCOME MEASURE: Four summary linkage indicators proposed by MacDermid and colleagues were estimated to compare the content coverage between Neuro-QoL and the ICF codes of core sets for MS, stroke, MS, and TBI...
April 3, 2018: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/29597251/-appropriate-treatment-and-therapeutic-window-in-spasticity-treatment-with-incobotulinumtoxina-from-100-to-1000-units
#3
Giancarlo Ianieri, Riccardo Marvulli, Giulia Alessia Gallo, Pietro Fiore, Marisa Megna
Many neurological diseases (ischemic and hemorrhagic stroke, multiple sclerosis, infant cerebral palsy, spinal cord injuries, traumatic brain injury, and other cerebrovascular disorders) may cause muscle spasticity. Different therapeutic strategies have been proposed for the treatment of spasticity. One of the major treatments for tone modulation is botulinum toxin type A (BTX-A), performed in addition to other rehabilitation strategies based on individualized multidisciplinary programs aimed at achieving certain goals for each patient...
March 28, 2018: Toxins
https://www.readbyqxmd.com/read/29589534/the-role-of-inflammation-in-neurological-disorders
#4
Diana Degan, Raffaele Ornello, Cindy Tiseo, Antonio Carolei, Simona Sacco, Francesca Pistoia
Traditionally neurological diseases have been classified, on the basis of their pathogenesis, into vascular, degenerative, inflammatory and traumatic diseases. Examples of the main inflammatory neurological diseases include multiple sclerosis, which is characterized by an immune-mediated immune response against myelin proteins, and meningoencephalitis, where the inflammatory response is triggered by infectious agents. However, recent evidence suggests a potential role of inflammatory mechanisms also in neurological conditions not usually categorized as inflammatory, such as Alzheimer's disease, Parkinson's disease, Huntington' disease, amyotrophic lateral sclerosis, stroke and traumatic brain injuries...
March 27, 2018: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/29580558/prevalence-and-predictors-of-depression-among-patients-with-epilepsy-stroke-and-multiple-sclerosis-using-the-cleveland-clinic-knowledge-program-within-the-neurological-institute
#5
Adele C Viguera, Youran Fan, Nicolas R Thompson, Brittany Lapin, Alexander Chaitoff, Sandra D Griffith, Deborah M Miller, Lara Jehi, Irene L Katzan
BACKGROUND: Neurological conditions carry a high risk of depression. Given this risk, the Neurological Institute (NI) at Cleveland Clinic has initiated systematic screening for depression using the 9-item Patient Health Questionnaire-9 (PHQ-9) embedded within its electronic medical record and its data capture system, the Knowledge Program (KP)1 . OBJECTIVE: We sought to (1) estimate the prevalence of depression among patients with epilepsy, stroke, and multiple sclerosis (MS); (2) identify risk factors for depression within each disease; and (3) determine differential risks and predictors across neurological disorders...
December 13, 2017: Psychosomatics
https://www.readbyqxmd.com/read/29564603/neurological-diseases-and-risk-of-suicide-attempt-a-case-control-study
#6
Astrid Eliasen, Kim Peder Dalhoff, Henrik Horwitz
INTRODUCTION: Neurological diseases have a profound impact on quality of life. We investigated the risk of suicide attempt in ten neurological diseases. METHODS: Case-control study. Cases were identified from the Danish Poison Information Centre database in the period 2006-2013. The prevalence of ten neurological diagnoses was compared with the prevalence in a randomly sampled age- and gender-matched control group. RESULTS: We identified 8974 cases of suicidal attempt and 89,740 controls...
March 21, 2018: Journal of Neurology
https://www.readbyqxmd.com/read/29523022/effectiveness-of-external-cues-to-facilitate-task-performance-in-people-with-neurological-disorders-a-systematic-review-and-meta-analysis
#7
Stephanie L Harrison, Kate E Laver, Kayla Ninnis, Cherie Rowett, Natasha A Lannin, Maria Crotty
PURPOSE: To examine in people with neurological disorders, which method/s of providing external cues to improve task performance are most effective. METHODS: Medline, EMBASE, and PsycINFO were systematically searched. Two reviewers independently screened, extracted data, and assessed the quality of the evidence using the Grading of Recommendations Assessment, Development and Evaluation (GRADE). RESULTS: Twenty six studies were included. Studies examined a wide-range of cues including visual, tactile, auditory, verbal, and multi-component cues...
March 9, 2018: Disability and Rehabilitation
https://www.readbyqxmd.com/read/29509545/neurological-and-psychiatric-disorders-in-psoriasis
#8
Man Amanat, Mona Salehi, Nima Rezaei
Psoriasis used to be known as a skin disorder; however, it can now be considered as a systemic disease with the involvement of multiple organs. Neurological and psychiatric disorders are some of the associated problems that can be observed in patients with psoriasis. Stroke, multiple sclerosis, seizure, migraine, restless leg syndrome, Parkinson's disease, Guillain-Barré syndrome, and myasthenia gravis are the reported neurological diseases, while depression, bipolar mood disorder, anxiety, psychosis, cognitive impairment, personality disorders, sexual disorders, sleep disturbance, and eating disorders are the recognized psychiatric presentations in patients with psoriasis...
March 6, 2018: Reviews in the Neurosciences
https://www.readbyqxmd.com/read/29507614/molecular-magnetic-resonance-imaging-of-endothelial-activation-in-the-central-nervous-system
#9
REVIEW
Maxime Gauberti, Antoine P Fournier, Fabian Docagne, Denis Vivien, Sara Martinez de Lizarrondo
Endothelial cells of the central nervous system over-express surface proteins during neurological disorders, either as a cause, or a consequence, of the disease. Since the cerebral vasculature is easily accessible by large contrast-carrying particles, it constitutes a target of choice for molecular magnetic resonance imaging (MRI). In this review, we highlight the most recent advances in molecular MRI of brain endothelial activation and focus on the development of micro-sized particles of iron oxide (MPIO) targeting adhesion molecules including intercellular adhesion molecule 1 (ICAM-1), vascular cell adhesion molecule 1 (VCAM-1), P-Selectin and E-Selectin...
2018: Theranostics
https://www.readbyqxmd.com/read/29504292/current-clinical-applications-of-diffusion-tensor-imaging-in-neurological-disorders
#10
REVIEW
Woo Suk Tae, Byung Joo Ham, Sung Bom Pyun, Shin Hyuk Kang, Byung Jo Kim
Diffusion-tensor imaging (DTI) is a noninvasive medical imaging tool used to investigate the structure of white matter. The signal contrast in DTI is generated by differences in the Brownian motion of the water molecules in brain tissue. Postprocessed DTI scalars can be used to evaluate changes in the brain tissue caused by disease, disease progression, and treatment responses, which has led to an enormous amount of interest in DTI in clinical research. This review article provides insights into DTI scalars and the biological background of DTI as a relatively new neuroimaging modality...
February 28, 2018: Journal of Clinical Neurology
https://www.readbyqxmd.com/read/29477412/safety-tolerability-and-effectiveness-of-dextromethorphan-quinidine-for-pseudobulbar-affect-among-study-participants-with-traumatic-brain-injury-results-from-the-prism-ii-open-label-study
#11
Flora M Hammond, William Sauve, Fred Ledon, Charles Davis, Andrea E Formella
BACKGROUND: Dextromethorphan 20mg /quinidine 10mg (DM/Q) was approved to treat pseudobulbar affect (PBA) based upon phase 3 trials conducted in participants with amyotrophic lateral sclerosis or multiple sclerosis. PRISM II evaluated DM/Q effectiveness, safety and tolerability for PBA following stroke, dementia or traumatic brain injury (TBI). OBJECTIVE: To report results from the TBI cohort of PRISM II, including a TBI-specific functional scale. DESIGN: Open-label trial evaluating twice daily DM/Q over 90 days...
February 22, 2018: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/29474391/support-service-utilization-and-out-of-pocket-payments-for-health-services-in-a-population-based-sample-of-adults-with-neurological-conditions
#12
Adebimpe O Obembe, Charlie H Goldsmith, Lisa A Simpson, Brodie M Sakakibara, Janice J Eng
BACKGROUND: Social support can help to deal with the consequences of neurological conditions and promote functional independence and quality of life. Our aim was to evaluate the impact of neurological conditions on the use of support and health-care services in a population-based sample of community-dwelling adults with neurological conditions. METHODS: Data were from the Survey of Living with Neurological Conditions in Canada, which was derived from a representative sample of household residents...
2018: PloS One
https://www.readbyqxmd.com/read/29472384/neuropsychological-testing
#13
EDITORIAL
Chiara Zucchella, Angela Federico, Alice Martini, Michele Tinazzi, Michelangelo Bartolo, Stefano Tamburin
Neuropsychological testing is a key diagnostic tool for assessing people with dementia and mild cognitive impairment, but can also help in other neurological conditions such as Parkinson's disease, stroke, multiple sclerosis, traumatic brain injury and epilepsy. While cognitive screening tests offer gross information, detailed neuropsychological evaluation can provide data on different cognitive domains (visuospatial function, memory, attention, executive function, language and praxis) as well as neuropsychiatric and behavioural features...
February 22, 2018: Practical Neurology
https://www.readbyqxmd.com/read/29455215/stroke-and-seizure-continue-to-be-the-major-brunt-of-in-patient-neurology-care-an-observation-from-teaching-hospital
#14
Azra Zafar, Majed Alabdali, Rizwana Shahid, Danah Aljaafari, Fahd A Al-Khamis, Aishah I Albakr, Saima Nazish, Abdulla A Al-Sulaiman, Alon Abraham
OBJECTIVE: To assess the burden and describe the pattern of neurological disorders requiring admissions in a teaching hospital of Al Khobar. METHODS: This is a retrospective, cross sectional study, carried out in the Neurology Department of King Fahd Hospital of the University from January 2009 to December 2016. Neurological disorders were grouped as ischemic stroke, intracerebral hemorrhage, transient ischemic attack, cerebral venous sinus thrombosis, seizure disorders, central nervous system infection, multiple sclerosis, neuropathies, myopathies, headache, dementia and miscellaneous group...
January 2018: Neurosciences: the Official Journal of the Pan Arab Union of Neurological Sciences
https://www.readbyqxmd.com/read/29454607/italian-wikipedia-and-epilepsy-an-infodemiological-study-of-online-information-seeking-behavior
#15
Francesco Brigo, Simona Lattanzi, Giorgia Giussani, Laura Tassi, Nicola Pietrafusa, Carlo Andrea Galimberti, Raffaele Nardone, Nicola Luigi Bragazzi, Oriano Mecarelli
Wikipedia is the most commonly accessed source of health information by both healthcare professionals and the lay public worldwide. We aimed to evaluate information-seeking behavior of Internet users searching the Italian Wikipedia for articles related to epilepsy and its treatment. Using Pageviews Analysis, we assessed the total and mean monthly views of articles from the Italian Wikipedia devoted to epilepsy, epileptic syndromes, seizure type, and antiepileptic drugs (AEDs) from January 1, 2015 to October 31, 2017...
February 14, 2018: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29428464/why-do-people-search-wikipedia-for-information-on-multiple-sclerosis
#16
F Brigo, S Lattanzi, N Bragazzi, R Nardone, M Moccia, L Lavorgna
BACKGROUND: Wikipedia is a frequently-accessed online source of health-related information. In this study we evaluated the number of views of the Italian Wikipedia articles related to multiple sclerosis (MS) and its treatment. METHODS: Using Pageviews Analysis we assessed the total views, and mean monthly and daily views of the Italian Wikipedia articles on MS and its treatments from 1 January 2015 to 31 October 2017. We compared the views of the article on MS with those for Alzheimer´s disease, epilepsy, migraine and stroke, and adjusted results for crude disease prevalence...
February 5, 2018: Multiple Sclerosis and related Disorders
https://www.readbyqxmd.com/read/29423615/defining-spasticity-a-new-approach-considering-current-movement-disorders-terminology-and-botulinum-toxin-therapy
#17
Dirk Dressler, Roongroj Bhidayasiri, Saeed Bohlega, Pedro Chana, Hsin Fen Chien, Tae Mo Chung, Carlo Colosimo, Markus Ebke, Klemens Fedoroff, Bernd Frank, Ryuji Kaji, Petr Kanovsky, Serdar Koçer, Federico Micheli, Olga Orlova, Sebastian Paus, Zvezdan Pirtosek, Maja Relja, Raymond L Rosales, José Alberto Sagástegui-Rodríguez, Paul W Schoenle, Gholam Ali Shahidi, Sofia Timerbaeva, Uwe Walter, Fereshte Adib Saberi
Spasticity is a symptom occurring in many neurological conditions including stroke, multiple sclerosis, hypoxic brain damage, traumatic brain injury, tumours and heredodegenerative diseases. It affects large numbers of patients and may cause major disability. So far, spasticity has merely been described as part of the upper motor neurone syndrome or defined in a narrowed neurophysiological sense. This consensus organised by IAB-Interdisciplinary Working Group Movement Disorders wants to provide a brief and practical new definition of spasticity-for the first time-based on its various forms of muscle hyperactivity as described in the current movement disorders terminology...
April 2018: Journal of Neurology
https://www.readbyqxmd.com/read/29414287/symbol-digit-modalities-test-adaptation-for-magnetic-resonance-imaging-environment-a-systematic-review-and-meta-analysis
#18
REVIEW
P H R Silva, C T Spedo, A A Barreira, R F Leoni
BACKGROUND: The Symbol Digit Modalities Test (SDMT) is widely used for cognitive evaluation of information processing speed (IPS), required in many cognitive operations. Despite being unspecific for different neurological disorders, it is sensitive to assess impaired performance related to stroke, Parkinson's disease, traumatic brain injury, and multiple sclerosis. However, in addition to evaluate the presence and severity of IPS impairment, it is of interest to determine the localization and integration of brain regions responsible for the functions assessed by the SDMT...
January 25, 2018: Multiple Sclerosis and related Disorders
https://www.readbyqxmd.com/read/29400677/male-and-female-opinions-about-orthotic-devices-of-the-lower-limb-a-multicentre-observational-study-in-patients-with-central-neurological-movement-disorders
#19
Eva Swinnen, Nina Lefeber, Amber Werbrouck, Yelena Gesthuizen, Lisa Ceulemans, Sofie Christiaens, Lise De Wael, Ronald Buyl, Stephan Ilsbroukx, Johan Van Nieuwenhoven, Marc Michielsen, Christophe Lafosse, Eric Kerckhofs
BACKGROUND AND OBJECTIVE: Because user-satisfaction and acceptance may partly determine the grade of compliance to an orthotic device (OD), the aim of this multicentre observational study was to inquire the reasons for acceptance and the user-satisfaction of an OD of the lower limb in male and female central neurological movement disorders (CNMD) patients. METHODS: Persons with CNMD having at least one prescribed OD of the lower limb were included. Two questionnaires were used: the MIRAD-ACCORT-II (reasons for acceptance) and a modified version of the D-QUEST 2...
2018: NeuroRehabilitation
https://www.readbyqxmd.com/read/29394876/the-development-of-biological-therapies-for-neurological-diseases-moving-on-from-previous-failures
#20
Hisham Qosa, Donna A Volpe
Although years of research have expanded the use of biologics for several clinical conditions, such development has not yet occurred in the treatment of neurological diseases. With the advancement of biologic technologies, there is promise for these therapeutics as novel therapeutic approaches for neurological diseases. Areas covered: In this article, the authors review the therapeutic potential of different types of biologics for the treatment of neurological diseases. Preclinical and clinical studies that investigate the efficacy and safety of biologics in the treatment of neurological diseases, namely Alzheimer's disease, amyotrophic lateral sclerosis, Parkinson disease, multiple sclerosis, and stroke, were reviewed...
February 2, 2018: Expert Opinion on Drug Discovery
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