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https://www.readbyqxmd.com/read/29035427/differences-in-the-korea-acute-myocardial-infarction-registry-compared-with-western-registries
#1
REVIEW
Doo Sun Sim, Myung Ho Jeong
The Korea Acute Myocardial Infarction Registry (KAMIR) is the first nationwide registry that reflects current therapeutic approaches and acute myocardial infarction (AMI) management in Korea. The results of the KAMIR demonstrated different risk factors and responses to medical and interventional treatments. The results indicated that the incidence of ST-elevation myocardial infarction (STEMI) was relatively high, and that the prevalence of dyslipidemia was relatively low with higher triglyceride and lower high-density lipoprotein cholesterol levels...
September 18, 2017: Korean Circulation Journal
https://www.readbyqxmd.com/read/29034751/less-than-two-versus-greater-than-two-hour-invasive-strategy-in-non-st-elevation-myocardial-infarction-a-meta-analysis-of-randomized-controlled-trials
#2
Poonam Velagapudi, Mohit Turagam, Dhaval Kholte, Sahil Khera, Parag Parikh, Omar Hyder, Herbert Aronow, Dawn Abbott
BACKGROUND: Optimal timing for an invasive strategy in non-ST elevation myocardial infarction (NSTEMI) is unclear. Whether clinical outcomes are improved with a less than two (LT2) compared with greater than two hour (GT2) invasive strategy remains to be determined. We performed a meta-analysis of randomized controlled trials (RCTs) comparing LT2 vs GT2 for NSTEMI. METHODS: A comprehensive literature search for RCTs comparing LT2 vs. GT2 in NSTEMI patients was performed...
October 16, 2017: Expert Review of Cardiovascular Therapy
https://www.readbyqxmd.com/read/29033510/admission-value-of-serum-cathepsin-d-level-can-be-useful-for-predicting-in-hospital-mortality-in-patients-with-nstemi
#3
Harun Kundi, Ahmet Balun, Hulya Cicekcioglu, Mustafa Cetin, Emrullah Kiziltunc, Canan Topcuoglu, Muhammed Fevzi Kilinckaya, Ender Ornek
BACKGROUND: We aimed to investigate the association of serum cathepsin D levels with in-hospital mortality and Syntax scores (SXscore) in non-ST elevation myocardial infarction (NSTEMI) patients. METHODS: A total of 88 patients were included in the study. The patients were divided into two groups: those with in-hospital mortality (-), and those with in-hospital mortality (+). The receiver operating characteristics curve was used to show the sensitivity and specificity of serum cathepsin D levels, and the optimal cut-off value for predicting in-hospital mortality and high SXscore...
July 2017: Acta Cardiologica Sinica
https://www.readbyqxmd.com/read/29033166/early-peripheral-endothelial-dysfunction-predicts-myocardial-infarct-extension-and-microvascular-obstruction-in-patients-with-st-elevation-myocardial-infarction
#4
Sérgio Bravo Baptista, Mariana Faustino, Luís Brizida, José Loureiro, João Augusto, João Abecasis, Célia Monteiro, Paulo Leal, Maura Nédio, Pedro Farto E Abreu, Victor Gil, Carlos Morais
INTRODUCTION AND OBJECTIVES: The role of endothelial dysfunction (ED) in patients with ST-elevation myocardial infarction (STEMI) is poorly understood. Peripheral arterial tonometry (PAT) allows non-invasive evaluation of ED, but has never been used for this purpose early after primary percutaneous coronary intervention (P-PCI). Our purpose was to analyze the relation between ED assessed by PAT and both the presence of microvascular obstruction (MVO) and infarct extension in STEMI patients...
October 12, 2017: Portuguese Journal of Cardiology: An Official Journal of the Portuguese Society of Cardiology
https://www.readbyqxmd.com/read/29025684/ninety-day-readmission-and-long-term-mortality-in-medicare-patients-%C3%A2-65-years-treated-with-ticagrelor-versus-prasugrel-after-percutaneous-coronary-intervention-from-the-blue-cross-blue-shield-of-michigan-cardiovascular-consortium
#5
Chris Song, Devraj Sukul, Milan Seth, James M Dupree, Akshay Khandelwal, Simon R Dixon, David Wohns, Thomas LaLonde, Hitinder S Gurm
Ticagrelor and prasugrel were found to be superior to clopidogrel for the treatment of acute coronary syndrome (ACS) after percutaneous coronary intervention (PCI); however, the comparative effectiveness of these 2 drugs remains unknown. We compared postdischarge outcomes among older patients treated with ticagrelor versus prasugrel after PCI for ACS. We linked clinical data from PCIs performed in older patients (age ≥65) for ACS at 47 Michigan hospitals to Medicare fee-for-service claims from January 1, 2013, to December 31, 2014, to ascertain rates of 90-day readmission and long-term mortality...
August 30, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/29024334/intermediate-and-nonclassical-monocytes-show-heterogeneity-in-patients-with-different-types-of-acute-coronary-syndrome
#6
Math P G Leers, Chantal Stockem, Dianne Ackermans, Rinske Loeffen, Hugo Ten Cate, Johannes A Kragten, Kon-Siong G Jie
This study was performed to gain further insight in the heterogeneity of monocytes in the different categories of acute coronary syndrome (ACS), especially between patients with unstable angina pectoris, ST-elevation myocardial infarction (STEMI), and non-ST-elevation myocardial infarction (NSTEMI). For this purpose, blood samples were collected in the acute phase from patients presenting with an ACS. These samples were examined with multiparameter flow cytometry to identify the different monocyte subsets and to analyze the expression of monocyte-associated molecules...
October 11, 2017: Cytometry. Part A: the Journal of the International Society for Analytical Cytology
https://www.readbyqxmd.com/read/29023996/effect-of-sex-difference-in-clinical-presentation-stable-coronary-artery-disease-vs-unstable-angina-pectoris-or-non-st-elevation-myocardial-infarction-vs-st-elevation-myocardial-infarction-on-2-year-outcomes-in-patients-undergoing-percutaneous-coronary-intervention
#7
Xiao-Fang Tang, Ying Song, Jing-Jing Xu, Yuan-Liang Ma, Jia-Hui Zhang, Yi Yao, Chen He, Huan-Huan Wang, Ping Jiang, Lin Jiang, Ru Liu, Zhan Gao, Xue-Yan Zhao, Shu-Bin Qiao, Bo Xu, Yue-Jin Yang, Run-Lin Gao, Jin-Qing Yuan
OBJECTIVE: To determine whether there is a difference in 2-year prognosis among patients across the spectrum of coronary artery disease undergoing percutaneous coronary intervention (PCI). METHODS: We analyzed all consecutive patients undergoing PCI at a single center from 1/1-12/31/2013. Clinical presentations were compared between sexes according to baseline clinical, angiographic, and procedural characteristics and 2-year (mean 730 ± 30-day) outcomes. RESULTS: We grouped 10 724 consecutive patients based on sex and clinical presentation...
October 11, 2017: Journal of Interventional Cardiology
https://www.readbyqxmd.com/read/29023473/comparison-of-bioavailability-and-antiplatelet-action-of-ticagrelor-in-patients-with-st-elevation-myocardial-infarction-and-non-st-elevation-myocardial-infarction-a-prospective-observational-single-centre-study
#8
Piotr Adamski, Joanna Sikora, Ewa Laskowska, Katarzyna Buszko, Małgorzata Ostrowska, Julia M Umińska, Adam Sikora, Natalia Skibińska, Przemysław Sobczak, Urszula Adamska, Danuta Rość, Aldona Kubica, Przemysław Paciorek, Michał P Marszałł, Eliano P Navarese, Diana A Gorog, Jacek Kubica
BACKGROUND: Data from available studies suggest that the presence of ST-elevation myocardial infarction (STEMI) may be associated with delayed and attenuated ticagrelor bioavailability and effect compared with non-ST-elevation myocardial infarction (NSTEMI). METHODS: In a single-center, prospective, observational trial 73 patients with myocardial infarction (STEMI n = 49, NSTEMI n = 24) underwent a pharmacokinetic and pharmacodynamic assessment after a 180 mg ticagrelor loading dose (LD)...
2017: PloS One
https://www.readbyqxmd.com/read/29021273/improvement-in-care-and-outcomes-for-emergency-medical-service-transported-patients-with-st-elevation-myocardial-infarction-stemi-with-and-without-prehospital-cardiac-arrest-a-mission-lifeline-stemi-accelerator-study
#9
Kristian Kragholm, Di Lu, Karen Chiswell, Hussein R Al-Khalidi, Mayme L Roettig, Matthew Roe, James Jollis, Christopher B Granger
BACKGROUND: Patients with ST-elevation myocardial infarction (STEMI) with out-of-hospital cardiac arrest (OHCA) may benefit from direct transport to a percutaneous cardiac intervention (PCI) hospital but have previously been less likely to bypass local non-PCI hospitals to go to a PCI center. METHODS AND RESULTS: We reported time trends in emergency medical service transport and care of patients with STEMI with and without OHCA included from 171 PCI-capable hospitals in 16 US regions with participation in the Mission: Lifeline STEMI Accelerator program between July 1, 2012, and March 31, 2014...
October 11, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29020314/improved-outcomes-in-patients-with-st-elevation-myocardial-infarction-during-the-last-20%C3%A2-years-are-related-to-implementation-of-evidence-based-treatments-experiences-from-the-swedeheart-registry-1995-2014
#10
Karolina Szummer, Lars Wallentin, Lars Lindhagen, Joakim Alfredsson, David Erlinge, Claes Held, Stefan James, Thomas Kellerth, Bertil Lindahl, Annica Ravn-Fischer, Erik Rydberg, Troels Yndigegn, Tomas Jernberg
Aims: Impact of changes of treatments on outcomes in ST-elevation myocardial infarction (STEMI) patients in real-life health care has not been documented. Methods and results: All STEMI cases (n = 105.674) registered in the nation-wide SWEDEHEART registry between 1995 and 2014 were included and followed for fatal and non-fatal outcomes for up to 20 years. Most changes in treatment and outcomes occurred from 1994 to 2008. Evidence-based treatments increased: reperfusion from 66...
August 29, 2017: European Heart Journal
https://www.readbyqxmd.com/read/29020244/impact-of-total-occlusion-of-culprit-artery-in-acute-non-st-elevation-myocardial-infarction-a-systematic-review-and-meta-analysis
#11
Abdur R Khan, Harsh Golwala, Avnish Tripathi, Aref A Bin Abdulhak, Chirag Bavishi, Haris Riaz, Vishnu Mallipedi, Ambarish Pandey, Deepak L Bhatt
Aims: Total occlusion (TO) of the culprit artery usually presents with ST-elevation myocardial infarction. A subset of patients with TO present as non-ST segment elevation myocardial infarction (NSTEMI) without classic ST-elevation on the electrocardiogram. This may lead to delay in identification of these patients and further management. We performed a meta-analysis to estimate the difference in outcomes between totally occluded and non-occluded culprit arteries in patients with NSTEMI...
August 7, 2017: European Heart Journal
https://www.readbyqxmd.com/read/29016632/radial-artery-neointimal-hyperplasia-after-transradial-pci-serial-optical-coherence-tomography-volumetric-study
#12
Petr Kala, Jan Kanovsky, Tereza Novakova, Roman Miklik, Otakar Bocek, Martin Poloczek, Petr Jerabek, Lenka Prymkova, Tomas Ondrus, Jiri Jarkovsky, Milan Blaha, Gary S Mintz
AIMS: Transradial catheterization (TRC) is a dominant access site for coronary catheterization and percutaneous coronary interventions (PCI) in many centers. Previous studies reported higher intimal thickness of the radial artery (RA) wall in patients with a previous history of TRC. In this investigation the aim was to assess the intimal changes of RA using the optical coherence tomography (OCT) intravascular imaging in a serial manner. METHODS AND RESULTS: 100 patients with the diagnosis of non-ST-elevation myocardial infarction (nSTEMI) treated by PCI were enrolled (6 patients were excluded from this analysis because of occluded RA at follow-up [2 patients] and insufficient quality of OCT images [4 patients])...
2017: PloS One
https://www.readbyqxmd.com/read/28991770/transition-towards-transradial-approach-improves-outcomes-of-acute-myocardial-infarction-pci
#13
Oliver Kalpak, Donco Donev, Hristo Pejkov, Slobodan Antov, Gjorgji Kalpak, Sasko Kedev
INTRODUCTION AND AIM: Transradial (TRA) instead of transfemoral (TFA) approach strategy has been presented in research literature as superior access strategy especially for acute ST elevation myocardial infarction (STEMI) primary percutaneous coronary intervention (PCI). There is a paucity of registry-based data of outcomes from default TRA strategy compared to TFA. MATERIALS AND METHODS: All-comers STEMI PCI institutional Registry identified 1808 consecutive patients in time-frame of 40 months from 2007 to 2010, without making any exclusions...
September 1, 2017: Prilozi (Makedonska Akademija Na Naukite i Umetnostite. Oddelenie za Medicinski Nauki)
https://www.readbyqxmd.com/read/28988425/the-safety-and-effectiveness-of-adenosine-diphosphate-receptor-inhibitor-pretreatment-among-acute-myocardial-infarction-patients-treated-with-percutaneous-coronary-intervention-in-community-practice-insights-from-the-translate-acs-study
#14
Mark B Effron, Tracy Y Wang, Gregg C Fonarow, Timothy D Henry, Marjorie E Zettler, Brian A Baker, Lisa A McCoy, Eric D Peterson
OBJECTIVES: To understand the optimal timing of adenosine diphosphate (ADP) receptor inhibitor pretreatment prior to percutaneous coronary intervention (PCI) among acute myocardial infarction (MI) patients. BACKGROUND: The role of ADP receptor inhibitor pretreatment in this population is unclear. METHODS: A total of 9,251 ADP receptor inhibitor-naïve MI patients undergoing PCI at 229 TRANSLATE-ACS sites were evaluated. Adjusted risks of in-hospital major adverse cardiovascular events (MACE) and major bleeding were compared among patients with and without pretreatment using inverse probability-weighted propensity adjustment...
October 8, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28987393/perioperative-outcomes-of-patients-undergoing-lobectomy-on-clopidogrel
#15
Scott M Atay, Arlene M Correa, Wayne L Hofstetter, Reza J Mehran, David C Rice, Jack A Roth, Boris Sepesi, Stephen G Swisher, Ara A Vaporciyan, Garrett Walsh, Mara B Antonoff
BACKGROUND: Perioperative management of antiplatelet therapy for patients undergoing pulmonary resection must balance the risk of cardiovascular events with that of hemorrhage. An optimal approach has not been defined in this population. We sought to characterize outcomes of patients undergoing pulmonary lobectomy on antiplatelet therapy with clopidogrel. METHODS: A prospective institutional database was retrospectively reviewed to identify all patients undergoing pulmonary lobectomy from 2007 to 2015 who received perioperative clopidogrel...
October 4, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28986063/utility-of-the-0-hour-1-hour-high-sensitivity-cardiac-troponin-t-algorithm-in-asian-patients-with-suspected-non-st-elevation-myocardial-infarction
#16
Masayuki Shiozaki, Kenji Inoue, Satoru Suwa, Chien-Chang Lee, Yuichi Chikata, Junko Ishiura, Yuki Kimura, Kentaro Fukuda, Hiroshi Tamura, Yasumasa Fujiwara, Masataka Sumiyoshi, Hiroyuki Daida
BACKGROUND: A rapid rule-out or rule-in protocol based on the 0-hour/1-hour algorithm using high-sensitivity cardiac troponin T is recommended by the European Society of Cardiology. However, Asian data are not available. METHODS: This prospective cohort study included 413 patients with suspected non-ST elevation myocardial infarction in 3 hospitals in Japan and Taiwan from November 2014 to April 2017. Patients were divided into 3groups-rule-out, observe, and rule-in-according to the algorithm...
September 30, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28985265/health-related-quality-of-life-in-older-patients-with-acute-coronary-syndrome-randomised-to-an-invasive-or-conservative-strategy-the-after-eighty-randomised-controlled-trial
#17
Nicolai Tegn, Michael Abdelnoor, Lars Aaberge, Anette Hylen Ranhoff, Knut Endresen, Erik Gjertsen, Rita Skårdal, Lars Gullestad, Bjørn Bendz
Objective: in the After Eighty study (ClinicalTrials.gov.number, NCT01255540), patients aged 80 years or more, with non-ST-elevation myocardial infarction (NSTEMI), and unstable angina pectoris (UAP), were randomised to either an invasive or conservative management approach. We sought to compare the effects of these management strategies on health related quality of life (HRQOL) after 1 year. Methods: the After Eighty study was a prospective randomised controlled multicenter trial...
July 13, 2017: Age and Ageing
https://www.readbyqxmd.com/read/28982497/characterization-of-the-average-daily-ischemic-and-bleeding-risk-after-primary-pci-for-stemi
#18
RANDOMIZED CONTROLLED TRIAL
Gennaro Giustino, Roxana Mehran, George D Dangas, Ajay J Kirtane, Björn Redfors, Philippe Généreux, Sorin J Brener, Jayne Prats, Stuart J Pocock, Efthymios N Deliargyris, Gregg W Stone
BACKGROUND: The risk of recurrent ischemic and bleeding events after primary percutaneous coronary intervention (PCI) for ST-segment elevation myocardial infarction (STEMI) may not be uniform over time, which may affect the benefit-to-risk ratio of guideline-recommended antithrombotic therapies in different intervals. OBJECTIVES: This study sought to characterize the average daily ischemic rates (ADIRs) and average daily bleeding rates (ADBRs) within the first year after primary PCI for STEMI...
October 10, 2017: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/28974496/outcome-of-stable-patients-with-acute-myocardial-infarction-and-coronary-artery-bypass-surgery-within-48%C3%A2-hours-a-single-center-retrospective-experience
#19
Christina Grothusen, Christine Friedrich, Johannes Loehr, Jette Meinert, Eva Ohnewald, Ulysses Ulbricht, Tim Attmann, Assad Haneya, Katharina Huenges, Sandra Freitag-Wolf, Jan Schoettler, Jochen Cremer
BACKGROUND: The optimal timing of coronary artery bypass grafting (CABG) in clinically stable patients with acute myocardial infarction who are unsuitable for percutaneous coronary intervention is unclear. We report our experience with early CABG in these patients. METHODS AND RESULTS: Between January 2001 and May 2015, 766 patients with ST-segment-elevation myocardial infarction (STEMI, n=305) or non-STEMI (NSTEMI, n=461) not including cardiogenic shock underwent CABG within 48 hours at our department...
October 3, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28966444/percutaneous-coronary-intervention-and-inpatient-mortality-in-patients-with-advanced-chronic-kidney-disease-presenting-with-acute-coronary-syndrome
#20
Brijesh Patel, Mahek Shah, Raman Dusaj, Sharon Maynard, Nainesh Patel
Chronic kidney disease (CKD) is an important risk factor for coronary artery disease, yet patients with CKD are less likely to undergo coronary angiography and percutaneous coronary intervention (PCI). We retrospectively analyzed the 2006-2012 National Inpatient Sample Database to examine the temporal trends in coronary angiography and PCI among patients without CKD, with advanced CKD (CKD III-V), and with end-stage renal disease (ESRD) presenting with unstable angina/non-ST elevation myocardial infarction (NSTE-ACS) and ST-elevation myocardial infarction (STEMI)...
October 2017: Proceedings of the Baylor University Medical Center
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