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heart rate variability and well-being

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https://www.readbyqxmd.com/read/28815597/cardiac-action-potential-repolarization-re-visited-early-repolarization-shows-all-or-none-behaviour
#1
Beatriz Trenor, Karen Cardona, Javier Saiz, Denis Noble, Wayne Giles
In healthy mammalian hearts the action potential (AP) waveform initiates and modulates each contraction, or heartbeat. As a result, action potential height and duration are key physiological variables. In addition, rate-dependent changes in ventricular action potential duration (APD), and variations in APD at a fixed heart rate, are both reliable biomarkers of electrophysiological stability. Present guidelines for the likelihood that candidate drugs will increase arrhythmias rely on small changes in APD and Q-T intervals as criteria for Safety Pharmacology decisions...
August 17, 2017: Journal of Physiology
https://www.readbyqxmd.com/read/28814378/mhealth-technologies-for-palliative-care-patients-at-the-interface-of-in-patient-to-outpatient-care-protocol-of-feasibility-study-aiming-to-early-predict-deterioration-of-patient-s-health-status
#2
Gudrun Theile, Vanessa Klaas, Gerhard Tröster, Matthias Guckenberger
BACKGROUND: Palliative care patients are a particularly vulnerable population and one of the critical phases in patients' trajectories is discharge from specialized in-patient palliative care into outpatient care, where availability of a palliative care infrastructure is highly variable. A relevant number of potentially avoidable readmissions and emergency visits of palliative patients is observed due to rapid exacerbation of symptoms indicating the need for a closer patient monitoring...
August 16, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/28813842/using-wearable-physiological-sensors-to-predict-energy-expenditure
#3
Kimberly A Ingraham, Daniel P Ferris, C David Remy
Lower-limb assistive robotic devices are often evaluated by measuring a reduction in the user's energy cost. Using indirect calorimetry to estimate energy cost is poorly suited for real-time estimation and long-term collection. The goal of this study was to use data from wearable sensors to predict energy cost with better temporal resolution and less variability than breath measurements. We collected physiological data (heart rate, electrodermal activity, skin temperature) and mechanical data (EMG, accelerometry) from three healthy subjects walking on a treadmill at various speeds on level ground, inclined, and backwards...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28809848/a-multimodal-dataset-for-various-forms-of-distracted-driving
#4
Salah Taamneh, Panagiotis Tsiamyrtzis, Malcolm Dcosta, Pradeep Buddharaju, Ashik Khatri, Michael Manser, Thomas Ferris, Robert Wunderlich, Ioannis Pavlidis
We describe a multimodal dataset acquired in a controlled experiment on a driving simulator. The set includes data for n=68 volunteers that drove the same highway under four different conditions: No distraction, cognitive distraction, emotional distraction, and sensorimotor distraction. The experiment closed with a special driving session, where all subjects experienced a startle stimulus in the form of unintended acceleration-half of them under a mixed distraction, and the other half in the absence of a distraction...
August 15, 2017: Scientific Data
https://www.readbyqxmd.com/read/28804896/load-dependence-of-myocardial-deformation-variables-a-clinical-strain-echocardiographic-study
#5
M Fredholm, K Jörgensen, E Houltz, S-E Ricksten
BACKGROUND: The effects of left ventricular (LV) loading on myocardial deformation variables are not well-studied in the clinical setting. In the present study, we evaluated the effects of isolated changes in preload, afterload and heart rate on LV longitudinal strain, systolic (SR-S) and early diastolic strain rate (SR-E) in post-cardiac surgery patients. METHODS: Twenty-one patients were studied early after cardiac surgery. Longitudinal myocardial strain and SR were analysed off-line using 2-D speckle echocardiography...
August 13, 2017: Acta Anaesthesiologica Scandinavica
https://www.readbyqxmd.com/read/28782142/influence-of-gestational-diabetes-on-the-fetal-autonomic-nervous-system-a-study-using-phase-rectified-signal-averaging-analysis
#6
Silvia M Lobmaier, Javier U Ortiz, Maria Sewald, Alexander Müller, Georg Schmidt, Bernhard Haller, Renate Oberhoffer, Karl T M Schneider, Dino A Giussani, Annette Wacker-Gußmann
OBJECTIVES: Maternal gestational diabetes (GDM) is known to influence fetal physiology. Phase-rectified signal averaging (PRSA), an innovative signal processing technique, can be used to investigate signals obtained from fetal heart. The PRSA calculated variables "average acceleration capacity" (AAC) and "average deceleration capacity" (ADC) are established indices of autonomic nervous system (ANS) function. The aim of this study was to evaluate the influence of gestational diabetes on the fetal ANS in human pregnancy using PRSA...
August 7, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28765033/assessment-of-butorphanol-azaperone-medetomidine-combination-as-anesthesia-for-semen-collection-and-evaluation-of-semen-quality-in-white-tailed-deer-odocoileus-virginianus
#7
S M Kirschner, R Rodenkirch
The aim of this current study was to evaluate the level of anesthesia produced by a combination of butorphanol-azaperone-medetomidine (BAM) for semen collection by electroejaculation on captive white-tailed bucks (Odocoileus virginianus). Ten male white-tailed deer, weighing 68.2-115.9kg, ranging in age from one to four years were randomly selected from housing pens and anesthetized with the BAM drug combination at a dose volume of 2.0mL each. Semen was collected from each animal using a standard cervid electroejaculation protocol while under BAM anesthesia...
July 25, 2017: Animal Reproduction Science
https://www.readbyqxmd.com/read/28757792/a-heart-failure-management-program-using-shared-medical-appointments
#8
Allison J Carroll, Hillary L Howrey, Susan Payvar, Kristen Deshida-Such, Mayank Kansal, Charanjit K Brar
BACKGROUND: Disease management programs for heart failure (HF) effectively reduce HF-related hospitalization rates and mortality. Shared medical appointments (SMAs) offer a cost-effective delivery method for HF disease management programs. However, few studies have evaluated this cost-effective delivery method of HF disease management among Veterans with acute HF. We hypothesized that Veterans who attended a multidisciplinary HF-SMA clinic promoting HF self-management, compared those who only received individual treatment through the HF specialty clinic, would have better 12-month hospitalization outcomes...
April 2017: Federal Practitioner: for the Health Care Professionals of the VA, DoD, and PHS
https://www.readbyqxmd.com/read/28757232/the-joy-of-heartfelt-music-an-examination-of-emotional-and-physiological-responses
#9
Emily Lynar, Erin Cvejic, Emery Schubert, Ute Vollmer-Conna
Music-listening can be a powerful therapeutic tool for mood rehabilitation, yet quality evidence for its validity as a singular treatment is scarce. Specifically, the relationship between music-induced mood improvement and meaningful physiological change, as well as the influence of music- and person-related covariates on these outcomes are yet to be comprehensively explored. Ninety-four healthy participants completed questionnaires probing demographics, personal information, and musical background. Participants listened to two prescribed musical pieces (one classical, one jazz), an "uplifting" piece of their own choice, and an acoustic control stimulus (white noise) in randomised order...
July 27, 2017: International Journal of Psychophysiology
https://www.readbyqxmd.com/read/28756943/evaluation-of-stress-response-using-psychological-biological-and-electrophysiological-markers-during-immersive-simulation-of-life-threatening-events-in-multidisciplinary-teams
#10
D A Ghazali, I Darmian-Rafei, J Nadolny, P Sosner, S Ragot, D Oriot
Stress might impair clinical performance in real life and in simulation-based education (SBE). Subjective or objective measures can be used to assess stress during SBE. This monocentric study aimed to evaluate the effects of simulation of life-threatening events on measurements of various stress parameters (psychological, biological, and electrophysiological parameters) in multidisciplinary teams (MDTs) during SBE. The effect of gender and status of participants on stress response was also investigated. Twelve emergency MDTs of 4 individuals were recruited for an immersive simulation session...
July 27, 2017: Australian Critical Care: Official Journal of the Confederation of Australian Critical Care Nurses
https://www.readbyqxmd.com/read/28749715/insomnia-and-autonomic-function-predict-well-being-in-patients-receiving-palliative-care
#11
Marco Warth, Jens Kessler, Hubert J Bardenheuer
BACKGROUND: The improvement of health-related quality of life (HRQOL) is one of the main treatment goals in end-of-life care. Although definitions and conceptualizations remain heterogeneous, many researchers proposed HRQOL to be considered as subjective patient well-being. However, research on its determinants in palliative care is rare, and little is known about the interplay between psychological and biological variables. OBJECTIVE: The aim of this study was to explain differences in terminally ill patients' acute well-being (AWB) by use of a multimethod approach, examining both self-ratings and physiological predictors...
July 27, 2017: Journal of Palliative Medicine
https://www.readbyqxmd.com/read/28741871/pharmacodynamics-pharmacokinetics-safety-and-tolerability-of-the-novel-dual-glucose-dependent-insulinotropic-polypeptide-glucagon-like-peptide-1-agonist-rg7697-after-single-subcutaneous-administration-in-healthy-subjects
#12
Agnès Portron, Shirin Jadidi, Neena Sarkar, Richard DiMarchi, Christophe Schmitt
AIMS: To evaluate the pharmacodynamics, pharmacokinetics and safety of single subcutaneous (s.c.) injection of ascending doses of RG7697, a dual glucose-dependent insulinotropic polypeptide/glucagon-like peptide-1 agonist, in healthy subjects. METHODS: A total of 51 healthy volunteers were enrolled in this double-blind, placebo-controlled study investigating RG7697 doses ranging from 0.03 to 5 mg. Adverse events (AEs) were monitored and drug concentrations, fasting glycaemic variables, vital signs, ECG, antibody formation and routine laboratory variables were assessed...
July 25, 2017: Diabetes, Obesity & Metabolism
https://www.readbyqxmd.com/read/28732265/chronic-work-stress-and-decreased-vagal-tone-impairs-decision-making-and-reaction-time-in-jockeys
#13
Kathleen Landolt, Paul Maruff, Ben Horan, Michael Kingsley, Glynda Kinsella, Paul D O'Halloran, Matthew W Hale, Bradley J Wright
The inverse relationship between acute stress and decision-making is well documented, but few studies have investigated the impact of chronic stress. Jockeys work exhaustive schedules and have extremely dangerous occupations, with safe performance requiring quick reaction time and accurate decision-making. We used the effort reward imbalance (ERI) occupational stress model to assess the relationship of work stress with indices of stress physiology and decision-making and reaction time. Jockeys (N=32) completed computerised cognitive tasks (Cogstate) on two occasions; September and November (naturally occurring lower and higher stress periods), either side of an acute stress test...
July 14, 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/28731559/association-between-anthropometric-measures-of-regional-fat-mass-and-heart-rate-variability-in-obese-women
#14
Marina Rastović, Biljana Srdić-Galić, Oto Barak, Edita Stokić
AIM: Impaired autonomic function could be the mechanism for the development of cardiometabolic diseases in obesity. Hence, simple anthropometric measures of overall and central obesity could be screening markers for autonomic imbalance. We analysed the relationship between heart rate variability (HRV) parameters and obesity indicators. METHODS: Sixty-three obese women underwent blood pressure, lipids and anthropometric measurements, body composition assessment, HOMA (homeostasis model assessment) index calculation and short-term HRV analysis...
February 2017: Nutrition & Dietetics: the Journal of the Dietitians Association of Australia
https://www.readbyqxmd.com/read/28725199/heart-performance-determination-by-visualization-in-larval-fishes-influence-of-alternative-models-for-heart-shape-and-volume
#15
Prescilla Perrichon, Martin Grosell, Warren W Burggren
Understanding cardiac function in developing larval fishes is crucial for assessing their physiological condition and overall health. Cardiac output measurements in transparent fish larvae and other vertebrates have long been made by analyzing videos of the beating heart, and modeling this structure using a conventional simple prolate spheroid shape model. However, the larval fish heart changes shape during early development and subsequent maturation, but no consideration has been made of the effect of different heart geometries on cardiac output estimation...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28724493/oral-transmucosal-detomidine-gel-in-new-zealand-white-rabbits-oryctolagus-cuniculus
#16
Morika D Williams, C Tyler Long, Jessica R Durrant, Gabriel P McKeon, Heather R Shive, Emily H Griffith, Kristen M Messenger, Richard E Fish
Handling and restraining rabbits for routine procedures may be impossible without prior sedation, result in unnecessary stress or injury to the rabbit or handler, and increase experimental variability. Parenteral administration of sedatives can cause stress also, as well as localized pain and tissue damage, especially in fractious animals. Detomidine hydrochloride, an α2-adrenergic receptor agonist, is commercially available in an oral transmucosal (OTM) gel formulation that is FDA-approved for sedation and restraint in horses...
July 1, 2017: Journal of the American Association for Laboratory Animal Science: JAALAS
https://www.readbyqxmd.com/read/28721034/readmission-after-copd-exacerbation-scale-determining-30-day-readmission-risk-for-copd-patients
#17
Christine Sm Lau, Brianna L Siracuse, Ronald S Chamberlain
BACKGROUND: COPD affects over 13 million Americans, and accounts for over half a million hospitalizations annually. The Hospital Readmission Reduction Program, established by the Affordable Care Act requires the Centers for Medicare and Medicaid Services to reduce payments to hospitals with excess readmissions for COPD as of 2015. This study sought to develop a predictive readmission scale to identify COPD patients at higher readmission risk. METHODS: Demographic and clinical data on 339,389 patients from New York and California (derivation cohort) and 258,113 patients from Washington and Florida (validation cohort) were abstracted from the State Inpatient Database (2006-2011), and the Readmission After COPD Exacerbation (RACE) Scale was developed to predict 30-day readmission risk...
2017: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/28709953/association-of-hemodynamic-variables-with-in-hospital-mortality-and-favorable-neurological-outcomes-in-post-cardiac-arrest-care-with-targeted-temperature-management
#18
Chien-Hua Huang, Min-Shan Tsai, Hooi Nee Ong, Weiting Chen, Chih-Hung Wang, Wei-Tien Chang, Tzung-Dau Wang, Shyr-Chyr Chen, Matthew Huei-Ming Ma, Wen-Jone Chen
PURPOSE: Although hemodynamic instability is expected during the post-cardiac arrest period, the implications of hemodynamic parameters for outcomes remain unclear. Each phase of targeted temperature management (TTM) affects hemodynamic responses differently. This study aims to investigate the association of hemodynamic parameters with outcomes in patients receiving TTM after cardiac arrest. METHODS: The study prospectively enrolled patients who were treated with TTM (33°C for 24h) after cardiac arrest...
July 11, 2017: Resuscitation
https://www.readbyqxmd.com/read/28709155/variable-accuracy-of-wearable-heart-rate-monitors-during-aerobic-exercise
#19
Stephen Gillinov, Muhammad Etiwy, Robert Wang, Gordon Blackburn, Dermot Phelan, A Marc Gillinov, Penny Houghtaling, Hoda Javadikasgari, Milind Y Desai
PURPOSE: Athletes and members of the public increasingly rely on wearable HR monitors to guide physical activity and training. The accuracy of newer, optically based monitors is unconfirmed. We sought to assess the accuracy of five optically based HR monitors during various types of aerobic exercise. METHODS: Fifty healthy adult volunteers (mean ± SD age = 38 ± 12 yr, 54% female) completed exercise protocols on a treadmill, a stationary bicycle, and an elliptical trainer (±arm movement)...
August 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28705170/can-lokomat-therapy-with-children-and-adolescents-be-improved-an-adaptive-clinical-pilot-trial-comparing-guidance-force-path-control-and-freed
#20
Tabea Aurich-Schuler, Fabienne Grob, Hubertus J A van Hedel, Rob Labruyère
BACKGROUND: Robot-assisted gait therapy is increasingly being used in pediatric neurorehabilitation to complement conventional physical therapy. The robotic device applied in this study, the Lokomat (Hocoma AG, Switzerland), uses a position control mode (Guidance Force), where exact positions of the knee and hip joints throughout the gait cycle are stipulated. Such a mode has two disadvantages: Movement variability is restricted, and patients tend to walk passively. Kinematic variability and active participation, however, are crucial for motor learning...
July 14, 2017: Journal of Neuroengineering and Rehabilitation
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