keyword
MENU ▼
Read by QxMD icon Read
search

Dengue serology in children

keyword
https://www.readbyqxmd.com/read/27821884/measuring-haitian-children-s-exposure-to-chikungunya-dengue-and-malaria
#1
Mathieu Jp Poirier, Delynn M Moss, Karla R Feeser, Thomas G Streit, Gwong-Jen J Chang, Matthew Whitney, Brandy J Russell, Barbara W Johnson, Alison J Basile, Christin H Goodman, Amanda K Barry, Patrick J Lammie
OBJECTIVE: To differentiate exposure to the newly introduced chikungunya virus from exposure to endemic dengue virus and other pathogens in Haiti. METHODS: We used a multiplex bead assay to detect immunoglobulin G (IgG) responses to a recombinant chikungunya virus antigen, two dengue virus-like particles and three recombinant Plasmodium falciparum antigens. Most (217) of the blood samples investigated were collected longitudinally, from each of 61 children, between 2011 and 2014 but another 127 were collected from a cross-sectional sample of children in 2014...
November 1, 2016: Bulletin of the World Health Organization
https://www.readbyqxmd.com/read/27630853/effectiveness-of-pooled-platelet-transfusion-in-concordant-and-discordant-groups-among-dengue-patients
#2
Amoolya Bhat, Vijaya Chowdappa, Smita Surendra Masamatti
INTRODUCTION: Dengue affects more than 50 million people per year and is one of the most common causes of severe thrombocytopaenia. Thrombocytopaenia is a common complication of dengue and other viral fevers apart from malaria, typhoid, leptospirosis, leukaemia and megaloblastic anaemia. A platelet count of <20,000/μl is characteristically seen in dengue haemorrhagic fever and dengue fever. It results from immune complex mediated platelet destruction or bone marrow suppression. Severe thrombocytopaenia <10,000/μl is one of the indications for prophylactic platelet transfusion therapy to prevent haemorrhage...
July 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27621562/clinically-profiling-pediatric-patients-with-dengue
#3
Sriram Pothapregada, Banupriya Kamalakannan, Mahalaskhmy Thulasingham, Srinivasan Sampath
OBJECTIVE: To study the clinical profile and outcome of dengue fever in children at a tertiary care hospital in Puducherry. MATERIALS AND METHODS: All children (0-12 years of age) diagnosed and confirmed as dengue fever from August 2012 to January 2015 were reviewed retrospectively from hospital case records as per the revised World Health Organization guidelines for dengue fever. The diagnosis was confirmed by NS1 antigen-based ELISA test or dengue serology for IgM and IgG antibodies, and the data were analyzed using SPSS 16...
July 2016: Journal of Global Infectious Diseases
https://www.readbyqxmd.com/read/27553703/state-of-the-art-monitoring-in-treatment-of-dengue-shock-syndrome-a-case-series
#4
Steven L Moulton, Jane Mulligan, Anon Srikiatkhachorn, Siripen Kalayanarooj, Greg Z Grudic, Sharone Green, Robert V Gibbons, Gary W Muniz, Carmen Hinojosa-Laborde, Alan L Rothman, Stephen J Thomas, Victor A Convertino
BACKGROUND: Early recognition and treatment of circulatory volume loss is essential in the clinical management of dengue viral infection. We hypothesized that a novel computational algorithm, originally developed for noninvasive monitoring of blood loss in combat casualties, could: (1) indicate the central volume status of children with dengue during the early stages of "shock"; and (2) track fluid resuscitation status. METHODS: Continuous noninvasive photoplethysmographic waveforms were collected over a 5-month period from three children of Thai ethnicity with clinical suspicion of dengue...
August 24, 2016: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/27352870/licensed-dengue-vaccine-public-health-conundrum-and-scientific-challenge
#5
Scott B Halstead
A tetravalent live attenuated vaccine composed of chimeras of yellow fever 17D and the four dengue viruses (chimeric yellow fever dengue [CYD]) manufactured by Sanofi Pasteur has completed phase III clinical testing in over 35,000 children 2-16 years of age. The vaccine was recently licensed in four countries. During the first 2 years of observation, CYD vaccine efficacy ranged between 30% and 79% in 10 different countries with an overall efficacy of 56.8%. During year 3, there was an overall efficacy against hospitalization of 16...
June 27, 2016: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/27190911/is-reactive-dengue-ns1antigen-test-a-warning-call-for-hospital-admissions
#6
Sriram Pothapregada, Banupriya Kamalakannan, Mahalakshmy Thulasingam, Srinivasan Sampath
INTRODUCTION: Dengue fever is a major public health problem worldwide. The 2011 revised World Health Organization (WHO) guidelines have emphasized on early diagnosis and intervention to reduce the case fatality rate due to dengue fever. Rapid diagnostic tests like NS1 antigen assays have improved the detection of cases in early clinical phase of illness but its role as a predictor of severe dengue infection is not very clear. AIM: To evaluate the utility of NS1 Ag assay as an early diagnostic marker and predictor of severe dengue infection...
April 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27154331/characterization-of-the-2013-dengue-epidemic-in-myanmar-with-dengue-virus-1-as-the-dominant-serotype
#7
Mya Myat Ngwe Tun, Aung Kyaw Kyaw, Nader Makki, Rohitha Muthugala, Takeshi Nabeshima, Shingo Inoue, Daisuke Hayasaka, Meng Ling Moi, Corazon C Buerano, Saw Myat Thwe, Kyaw Zin Thant, Kouichi Morita
In 2013 in Myanmar, dengue epidemic occurred with 20,255 cases including 84 deaths. This study aimed to determine the serological and molecular characteristics of dengue virus (DENV) infection among children with clinical diagnosis of dengue hemorrhagic fever (DHF) or dengue shock syndrome (DSS) during this period. Single acute serum samples were collected from 300 children in Mandalay Children Hospital, Mandalay, Myanmar. Out of the 300 children, 175 (58.3%) and 183 (61%) were positive for anti-dengue IgM and anti-dengue IgG, respectively...
September 2016: Infection, Genetics and Evolution
https://www.readbyqxmd.com/read/26988170/epidemiology-and-neurological-complications-of-infection-by-the-zika-virus-a-new-emerging-neurotropic-virus
#8
Francisco J Carod-Artal
INTRODUCTION: The current epidemic outbreak due to Zika virus began in 2015 and since then it has been reported in 31 countries and territories in America. The epidemiological and clinical aspects related to infection by Zika virus are reviewed. DEVELOPMENT: Since 2007, 55 countries in America, Asia, Africa and Oceania have detected local transmission of the virus. This epidemic has affected almost 1.5 million people in Brazil. 80% of the cases are asymptomatic...
April 1, 2016: Revista de Neurologia
https://www.readbyqxmd.com/read/26976884/differences-in-liver-impairment-between-adults-and-children-with-dengue-infection
#9
Rosario Martínez Vega, Weerapong Phumratanaprapin, Benjaluck Phonrat, Jittima Dhitavat, Maleerat Sutherat, Vorada Choovichian
Dengue infection (DI) is a major vector-borne disease in southeast Asia and an important cause of morbidity. The complications such as hepatic impairment are common, and because the physiology of the liver differs between children and adults, the DI-associated liver impairments might be expected to differ as well. This study aims to compare the differences in liver impairment between adults and children with DI. We retrospectively studied 158 adults and 79 children with serologically confirmed DI admitted to the Bangkok Hospital for Tropical Diseases from 2008 to 2012...
May 4, 2016: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/26872216/the-epidemiology-virology-and-clinical-findings-of-dengue-virus-infections-in-a-cohort-of-indonesian-adults-in-western-java
#10
Herman Kosasih, Bachti Alisjahbana, Nurhayati, Quirijn de Mast, Irani F Rudiman, Susana Widjaja, Ungke Antonjaya, Harli Novriani, Nugroho H Susanto, Hadi Jusuf, Andre van der Ven, Charmagne G Beckett, Patrick J Blair, Timothy H Burgess, Maya Williams, Kevin R Porter
BACKGROUND: Dengue has emerged as one of the most important infectious diseases in the last five decades. Evidence indicates the expansion of dengue virus endemic areas and consequently the exponential increase of dengue virus infections across the subtropics. The clinical manifestations of dengue virus infection include sudden fever, rash, headache, myalgia and in more serious cases, spontaneous bleeding. These manifestations occur in children as well as in adults. Defining the epidemiology of dengue in a given area is critical to understanding the disease and devising effective public health strategies...
February 2016: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/26846603/is-ultrasound-a-useful-tool-to-predict-severe-dengue-infection
#11
Sriram Pothapregada, Poonam Kullu, Banupriya Kamalakannan, Mahalakshmy Thulasingam
OBJECTIVES: To study the role of ultrasound in children with dengue fever and determine its role in predicting the severity of the disease. METHODS: This was a retrospective hospital based study conducted from 1(st) August 2012 to January 31(st) 2015 at a tertiary care hospital in Puducherry. RESULTS: Two hundred and fifty four children were admitted with dengue fever and among them non-severe dengue and severe dengue were seen in 62.6 % and 37...
June 2016: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/26752727/scrub-typhus-in-rural-rajasthan-and-a-review-of-other-indian-studies
#12
Rupesh Masand, Ritesh Yadav, Alok Purohit, Balvir Singh Tomar
BACKGROUND: Scrub typhus is an acute febrile illness which has been reported from various parts of India with Rajasthan recently joining the list of affected states. AIM: To report a series of paediatric scrub typhus cases from rural Rajasthan. STUDY DESIGN: Retrospective review of children with scrub typhus admitted to the wards and paediatric intensive care unit (PICU) of a tertiary-care hospital. METHODS: The study was undertaken over an 8-month period from May to December 2013...
January 9, 2016: Paediatrics and International Child Health
https://www.readbyqxmd.com/read/26725457/clinical-profile-of-atypical-manifestations-of-dengue-fever
#13
Sriram Pothapregada, Banupriya Kamalakannan, Mahalakshmy Thulasingam
OBJECTIVES: To study the clinical profile and outcome of the atypical manifestations of dengue fever in children. METHODS: All children (0-12 y of age) diagnosed and confirmed as dengue fever at a tertiary care hospital at Puducherry, between the 1st of August 2012 and January 31st 2015 were reviewed retrospectively from hospital case records as per the revised World Health Organization (WHO) guidelines 2011 for dengue fever. The diagnosis was confirmed by NS1 antigen-based ELISA test or dengue serology for IgM and IgG antibodies and the data was analyzed using SPSS 16...
June 2016: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/26714510/role-of-platelet-transfusion-in-children-with-bleeding-in-dengue-fever
#14
Sriram Pothapregada, Banupriya Kamalakannan, Mahalakshmy Thulasingam
BACKGROUND & OBJECTIVES: The indications for platelet transfusion in dengue fever are clearly defined in World Health Organization (WHO) guidelines (2011) for dengue fever, but physicians face practical difficulty in its implementation in an epidemic setting. On one hand there is an intense social pressure created by the panic-struck parents to transfuse platelets in presence of bleeding and on the other hand there is a need for its judicious use as the requirement is more than its availability...
December 2015: Journal of Vector Borne Diseases
https://www.readbyqxmd.com/read/26635947/serum-aminotransferases-in-thai-children-with-dengue-infection
#15
Olarn Prommalikit, Usa Thisyakorn, Chule Thisyakorn
BACKGROUND: Hepatic manifestations are one of the unusual manifestations of dengue infection. OBJECTIVES: We conducted this study in order to study the pattern of serum aminotransferases and sequential changes before and after shock in Thai children with dengue infection. PATIENTS AND METHODS: Children who were clinically and serologically diagnosed as dengue infection and were admitted to King Chulalongkorn Memorial Hospital during a peroid of one year were enrolled...
December 2015: Iranian Journal of Pediatrics
https://www.readbyqxmd.com/read/26458156/secondary-dengue-virus-infections-during-the-2009-outbreak-in-buenos-aires
#16
E Tittarelli, P R Barrero, A S Mistchenko, L E Valinotto
OBJECTIVES: To evaluate the occurrence of secondary Dengue virus (DENV) infections during the 2009 outbreak in a non-endemic area. Viral loads were evaluated in serum from acute phase patients, comparing primary and secondary infection. METHODS: Serum samples from patients with clinical diagnosis of suspected dengue were referred to the Virology Laboratory at "Ricardo Gutiérrez" Children's Hospital. Dengue positive samples were classified as primary or secondary DENV infections through serological methods (anti-DENV IgM and IgG)...
October 12, 2015: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/26406240/value-of-routine-dengue-diagnostic-tests-in-urine-and-saliva-specimens
#17
Anne-Claire Andries, Veasna Duong, Sowath Ly, Julien Cappelle, Kim Srorn Kim, Patrich Lorn Try, Sopheaktra Ros, Sivuth Ong, Rekol Huy, Paul Horwood, Marie Flamand, Anavaj Sakuntabhai, Arnaud Tarantola, Philippe Buchy
BACKGROUND: Dengue laboratory diagnosis is essentially based on detection of the virus, its components or antibodies directed against the virus in blood samples. Blood, however, may be difficult to draw in some patients, especially in children, and sampling during outbreak investigations or epidemiological studies may face logistical challenges or limited compliance to invasive procedures from subjects. The aim of this study was to assess the possibility of using saliva and urine samples instead of blood for dengue diagnosis...
September 2015: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/26275255/dengue-virus-infection-need-for-appropriate-laboratory-tests-for-diagnosis-and-management-of-the-condition-in-children-during-an-outbreak
#18
Harshavardhini Palanivel, Shashikala Nair, Anandhalakshmi Subramaniyan, Philip Vivian Joseph Ratnam, Reba Kanungo
BACKGROUND: Outbreaks of dengue infection occur in several parts of India with clockwork precision closely related to changing seasons. Most recent outbreak in Puducherry occurred between October 2012 and January 2013, affected a sizable pediatric population. A prospective study was done to characterize the demographic, diagnostic and clinical profile of pediatric patients in a tertiary care center in Puducherry. MATERIALS AND METHODS: Data of patients serologically positive for either dengue NS1 antigen or anti-dengue IgM antibodies were analyzed...
July 2015: Indian Journal of Pathology & Microbiology
https://www.readbyqxmd.com/read/26156323/evidence-based-community-mobilization-for-dengue-prevention-in-nicaragua-and-mexico-camino-verde-the-green-way-cluster-randomized-controlled-trial
#19
RANDOMIZED CONTROLLED TRIAL
Neil Andersson, Elizabeth Nava-Aguilera, Jorge Arosteguí, Arcadio Morales-Perez, Harold Suazo-Laguna, José Legorreta-Soberanis, Carlos Hernandez-Alvarez, Ildefonso Fernandez-Salas, Sergio Paredes-Solís, Angel Balmaseda, Antonio Juan Cortés-Guzmán, René Serrano de Los Santos, Josefina Coloma, Robert J Ledogar, Eva Harris
OBJECTIVE: To test whether community mobilization adds effectiveness to conventional dengue control. DESIGN: Pragmatic open label parallel group cluster randomized controlled trial. Those assessing the outcomes and analyzing the data were blinded to group assignment. Centralized computerized randomization after the baseline study allocated half the sites to intervention, stratified by country, evidence of recent dengue virus infection in children aged 3-9, and vector indices...
2015: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/26117708/trends-in-the-patterns-of-igm-and-igg-antibodies-in-febrile-persons-with-suspected-dengue-in-barbados-an-english-speaking-caribbean-country-2006-2013
#20
Alok Kumar, Anders L Nielsen
Long-term seroprevalence studies of dengue have provided a measure of the degree of endemicity and future trends in disease prevalence and severity. In this study, we describe the seroprevalence of dengue antibodies in febrile persons with suspected acute dengue in Barbados. It is a retrospective population-based study of all febrile persons with suspected dengue from 2006 to 2013. All of the cases had IgM and IgG antibodies in the blood sample drawn between days 3 and 5 of their illness. Among the 8296 cases that were tested for IgM antibodies, 3037 (36...
November 2015: Journal of Infection and Public Health
keyword
keyword
95114
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"