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https://www.readbyqxmd.com/read/29679838/medico-legal-investigation-in-an-explicable-case-of-congenital-central-hypoventilation-syndrome-due-to-a-rare-variant-of-the-phox2b-gene
#1
Francesco Ventura, Rosario Barranco, Tiziana Bachetti, Paolo Nozza, Ezio Fulcheri, Antonella Palmieri, Isabella Ceccherini
The heterozygous PHOX2B gene mutation is related to congenital central hypoventilation syndrome (CCHS). It is characterized by defective autonomous nervous system development leading to inadequate breathing response to hypoxia and hypercapnia, leading to hypoventilation especially during non-REM sleep, but also during waking in the more severe cases. Herein we report a case of sudden death in a 28-day-old child. The mother reported the infant was found lying on her own bed in the prone position. The infant was wearing a romper and lying in her crib without any blanket or other objects...
April 17, 2018: Journal of Forensic and Legal Medicine
https://www.readbyqxmd.com/read/29679623/hyperglycemia-in-pregnancy-and-its-implications-for-a-woman-s-future-risk-of-cardiovascular-disease
#2
REVIEW
Ravi Retnakaran
It is well established that gestational diabetes mellitus (GDM) identifies a population of women who are at risk of ultimately developing type 2 diabetes (T2DM) later in life. Moreover, this relationship extends across the full spectrum of hyperglycemia in pregnancy, with lesser degrees of gestational dysglycemia identifying a proportionate gradient of future risk of T2DM. Importantly, a growing body of evidence suggests that an analogous relationship exists between hyperglycemia in pregnancy and a woman's long-term risk of cardiovascular disease (CVD), as well...
April 18, 2018: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/29676618/cancer-risk-from-paediatric-computed-tomography-scanning-implications-for-radiation-protection-in-medicine
#3
A Kesminiene, E Cardis
The use of computed tomography (CT) imaging is clearly beneficial for millions of patients. However, the potential adverse health effects, particularly cancer, of ionising radiation exposure from CT early in life are an issue of growing concern in the radiological protection, medical, and public health communities. Although efforts to quantify these effects have been conducted, the precision and accuracy of reported risks needs confirmation. EPI-CT, a European collaborative epidemiological study, was set up to quantify risks from paediatric CT to optimise paediatric diagnostic protocol...
January 1, 2018: Annals of the ICRP
https://www.readbyqxmd.com/read/29674313/key-lessons-and-impact-of-the-growing-healthy-mhealth-program-on-milk-feeding-timing-of-introduction-of-solids-and-infant-growth-quasi-experimental-study
#4
Rachel A Laws, Elizabeth A Denney-Wilson, Sarah Taki, Catherine G Russell, Miaobing Zheng, Eloise-Kate Litterbach, Kok-Leong Ong, Sharyn J Lymer, Rosalind Elliott, Karen J Campbell
BACKGROUND: The first year of life is an important window to initiate healthy infant feeding practices to promote healthy growth. Interventions delivered by mobile phone (mHealth) provide a novel approach for reaching parents; however, little is known about the effectiveness of mHealth for child obesity prevention. OBJECTIVE: The objective of this study was to determine the feasibility and effectiveness of an mHealth obesity prevention intervention in terms of reach, acceptability, and impact on key infant feeding outcomes...
April 19, 2018: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/29673875/intervention-strategies-to-improve-nutrition-and-health-behaviours-before-conception
#5
REVIEW
Mary Barker, Stephan U Dombrowski, Tim Colbourn, Caroline H D Fall, Natasha M Kriznik, Wendy T Lawrence, Shane A Norris, Gloria Ngaiza, Dilisha Patel, Jolene Skordis-Worrall, Falko F Sniehotta, Régine Steegers-Theunissen, Christina Vogel, Kathryn Woods-Townsend, Judith Stephenson
The nutritional status of both women and men before conception has profound implications for the growth, development, and long-term health of their offspring. Evidence of the effectiveness of preconception interventions for improving outcomes for mothers and babies is scarce. However, given the large potential health return, and relatively low costs and risk of harm, research into potential interventions is warranted. We identified three promising strategies for intervention that are likely to be scalable and have positive effects on a range of health outcomes: supplementation and fortification; cash transfers and incentives; and behaviour change interventions...
April 16, 2018: Lancet
https://www.readbyqxmd.com/read/29673391/parenting-resilient-kids-park-an-online-parenting-program-to-prevent-anxiety-and-depression-problems-in-primary-school-aged-children-study-protocol-for-a-randomised-controlled-trial
#6
Luwishennadige Madhawee N Fernando, Wan Hua Sim, Anthony F Jorm, Ron Rapee, Katherine A Lawrence, Marie B H Yap
BACKGROUND: Preventive efforts targeting childhood anxiety and depression symptoms have the potential to alter the developmental trajectory of depression and anxiety disorders across the lifespan. Substantial previous research suggests that modifiable parenting factors such as parental aversiveness and over-involvement are associated with childhood anxiety, depressive and internalising symptoms, indicating that parents can play a critical role in prevention. The Parenting Resilient Kids study is a new evidence-based online parenting program designed to prevent anxiety and depression problems in primary school-aged children by reducing family-based risk factors and enhancing protective factors through increased positive interactions between parent and child...
April 19, 2018: Trials
https://www.readbyqxmd.com/read/29672758/explaining-the-gender-gap-in-sickness-absence
#7
K A Østby, A Mykletun, W Nilsen
Background: In many western countries, women have a much higher rate of sickness absence than men. To what degree the gender differences in sickness absence are caused by gender differences in health is largely unknown. Aims: To assess to what degree the gender gap in sickness absence can be explained by health factors and work- and family-related stressors. Methods: Norwegian parents participating in the Tracking Opportunities and Problems (TOPP) study were asked about sickness absence and a range of factors possibly contributing to gender differences in sickness absence, including somatic and mental health, sleep problems, job control/demands, work-home conflicts, parent-child conflicts and stressful life events...
April 17, 2018: Occupational Medicine
https://www.readbyqxmd.com/read/29671836/children-s-experience-of-symptoms-narratives-through-words-and-images
#8
REVIEW
Barbara M Sourkes
Children who live with a complex chronic or life-threatening illness face extraordinary challenges. Whether they are receiving disease-oriented treatment (aimed at potential cure or prolongation of life) or palliative treatment-or both concurrently-our challenge is to enhance their comfort and minimize their distress. Symptom management is thus a critical component of pediatric palliative care. Symptoms may be either physical or psychological in nature (or a confluence of both) and their effective management has a direct impact on the child's quality of life...
April 19, 2018: Children
https://www.readbyqxmd.com/read/29671639/lifelong-parenting-of-adults-with-developmental-disabilities-growth-trends-over-20-years-in-midlife-and-later-life
#9
Eun Ha Namkung, Jan S Greenberg, Marsha R Mailick, Frank J Floyd
This research examined how parenting adults with developmental disabilities affects parental well-being beyond midlife and into old age. Parents of adults with developmental disabilities ( n = 249) and parents of adults without disabilities ( n = 9,016), studied in their early 50s and mid-60s, were longitudinally tracked into their early 70s. Compared to parents of adults without disabilities, parents of adults with disabilities showed a pattern of normative functioning in their 50s, followed by poorer well-being in their mid-60s, and further declines in health and well-being into the early 70s...
May 2018: American Journal on Intellectual and Developmental Disabilities
https://www.readbyqxmd.com/read/29671251/quality-of-life-of-middle-aged-adults-in-single-households-in-south-korea
#10
Hyun Jin Song, Susan Park, Jin-Won Kwon
PURPOSE: The number of single households has increased worldwide with middle-aged people in such households indicating the highest increase. However, there is a lack of studies on the topic. This study estimated the quality of life (QOL) by household type for middle-aged Korean adults. METHODS: We used the Korea National Health and Nutrition Examination Survey data from 2007 to 2015. QOL was analyzed using EQ-5D 3-level, and demographic and health-related variables were included as confounders...
April 18, 2018: Quality of Life Research
https://www.readbyqxmd.com/read/29670555/lexical-tones-in-mandarin-chinese-infant-directed-speech-age-related-changes-in-the-second-year-of-life
#11
Mengru Han, Nivja H de Jong, René Kager
Tonal information is essential to early word learning in tone languages. Although numerous studies have investigated the intonational and segmental properties of infant-directed speech (IDS), only a few studies have explored the properties of lexical tones in IDS. These studies mostly focused on the first year of life; thus little is known about how lexical tones in IDS change as children's vocabulary acquisition accelerates in the second year (Goldfield and Reznick, 1990; Bloom, 2001). The present study examines whether Mandarin Chinese mothers hyperarticulate lexical tones in IDS addressing 18- and 24-month-old children-at which age children are learning words at a rapid speed-vs...
2018: Frontiers in Psychology
https://www.readbyqxmd.com/read/29670006/diets-and-feeding-practices-during-the-first-1000-days-window-in-the-phnom-penh-and-north-eastern-districts-of-cambodia
#12
Somphos Vicheth Som, Sophonneary Prak, Arnaud Laillou, Ludovic Gauthier, Jacques Berger, Etienne Poirot, Frank T Wieringa
Although several health and development indicators have improved significantly in Cambodia, inadequate breastfeeding and inappropriate complementary feeding practices leave many children at high risk of malnutrition during the early stages of life. In 2014, the prevalence of wasting and stunting among Cambodian children under 5 were 10% and 32%, respectively. Thus, a strong focus on improving feeding practices within the first 1000 days window to reduce child malnutrition prevalence in Cambodia is needed. This cross-sectional study assessed the current feeding practices among of women of reproductive age, pregnant women, lactating women and children less than 24 months living in six districts from Phnom Penh and two rural provinces in the North East of Cambodia...
April 18, 2018: Nutrients
https://www.readbyqxmd.com/read/29668630/thoracolumbar-spinal-neurenteric-cyst-with-tethered-cord-syndrome-and-extreme-cervical-lordosis-in-a-child-a-case-report-and-literature-review
#13
Zhi Gang Lan, Seidu A Richard, Chuanfen Lei, Siqing Huang
RATIONALE: Neurenteric cysts, are rare benign tumors of the central nervous system that are mostly located in the spinal cord and predominantly seen in male children although adult form of the disorder also occurs. The etiology and treatment of this disorder is still a matter of debate. Our case further throws more light on the pathogenesis and treatment of this disorder. PATIENT CONCERNS: A 4-year-old boy presented with 5-month history of cervical lordosis and bilateral lower extremity pain that progressed to his abdomen and upper body...
April 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29668453/the-skin-and-the-eye-herpes-zoster-ophthalmicus-in-a-healthy-18-month-old-toddler
#14
Radka T Komitova, Oliana B Boykinova, Nina S Stoyanova
Herpes zoster, caused by reactivation of varicella-zoster virus, is uncommon in infancy. Even more uncommon is herpes zoster ophthalmicus, defined as herpes zoster of the ophthalmic branch of the fifth cranial nerve. Among healthy children, primary varicella-zoster virus infection during gestation as a result of maternal varicella or the first year of life is the major risk factor for development of herpes zoster in a relatively young age. Here we present an unusual case of herpes zoster ophthalmicus with dissemination in an immunocompetent toddler with favorable outcome...
March 1, 2018: Folia Medica
https://www.readbyqxmd.com/read/29668026/nicu-graduates-the-role-of-the-allied-health-team-in-follow-up
#15
Jane L Orton, Joy E Olsen, Katherine Ong, Rochelle Lester, Alicia J Spittle
Infants who graduate from the neonatal intensive care unit, including those infants born preterm and/or with brain injury, are at increased risk of long-term neurodevelopmental impairments. The developmental allied health team, consisting of physical therapy, occupational therapy, and speech pathology, is crucial in early evaluation of gross motor, fine motor, feeding, and language development. Surveillance of neurodevelopment in the first year of life is essential to ensure early detection of specific developmental delays and impairments, and to ensure timely referral for early intervention...
April 1, 2018: Pediatric Annals
https://www.readbyqxmd.com/read/29667920/child-life-services-in-an-epilepsy-monitoring-unit
#16
Daniel B Lowenstein, Mackenzie C Cervenka, Lauren Mitchell, Noelle Stewart, Eric H Kossoff, Sarah A Kelley
The goal of this study was to determine the value of a certified child life specialist (CCLS) on the patient and staff experiences in an epilepsy monitoring unit (EMU). We integrated a CCLS into the EMU for all children as well as adults with intellectual disability. We surveyed families to determine the impact of child life services on their stay. EMU staff completed questionnaires to determine perceived impact to their job performance from the integration of the CCLS. All of the families (pediatric and adult patients) who responded to the survey reported the presence of the CCLS improved their hospital experience...
April 1, 2018: Clinical Pediatrics
https://www.readbyqxmd.com/read/29667311/how-japanese-nurses-participate-in-decision-making-infants-with-congenital-life-threatening-conditions
#17
Sohei Shitaya, Nobue Nakamura, Naho Sato
BACKGROUND: In Japan, owing to the progress in medical technology, more children with congenital life-threatening conditions survive than ever before. Nurses who care for these children may also influence decision making in difficult situations. AIM: We aimed to describe Japanese nurses' approach toward medical decision making when caring for families of infants with congenital life-threatening conditions. Frequently, these nurses must care for and support parents with ambivalent feelings...
April 2018: International Journal of Nursing Practice
https://www.readbyqxmd.com/read/29665761/expert-rater-agreement-and-inter-intrarater-reliability-for-the-furtado-gallagher-computerized-observational-movement-pattern-assessment-system
#18
Ovande Furtado, Jere D Gallagher
Fundamental movement skills (FMS) play a crucial role in a child's motor skill development, as their mastery is related to the acquisition and mastery of specialized sport skills and to a child's general health through the prevention of weight gain and increased level of physical activity. Thus, the accurate and reliable measurement of FMS is of related importance. This article presents the results of two studies intended to assess expert-rater agreement and inter-/intrarater scoring reliability in the administration of a new observational FMS instrument, the Furtado-Gallagher Computerized Observational Movement Pattern Assessment System (FG-COMPASS)...
January 1, 2018: Perceptual and Motor Skills
https://www.readbyqxmd.com/read/29665122/impact-of-untreated-dental-caries-on-the-quality-of-life-of-brazilian-children-population-based-study
#19
Sâmara Luciana de Andrade Lima, Caroline Chavier Pereira Santana, Marco Aurélio Benini Paschoal, Saul Martins Paiva, Meire Coelho Ferreira
BACKGROUND: The assessment of oral health should consider clinical and biopsychosocial aspects. AIM: To evaluate the impact of untreated dental caries on the quality of life of children. DESIGN: A cross-sectional study was conducted with 647 Brazilian children. The Child Perceptions Questionnaire (CPQ8-10 ) and the 'oral health' global indicator were administered to the children and used as the outcomes. Parents answered a general questionnaire, and oral clinical examinations were performed...
April 17, 2018: International Journal of Paediatric Dentistry
https://www.readbyqxmd.com/read/29664972/the-impact-of-social-and-psychological-consequences-of-disease-on-judgments-of-disease-severity-an-experimental-study
#20
Nicholas B King, Sam Harper, Meredith Young, Sarah C Berry, Kristin Voigt
BACKGROUND: The Global Burden of Disease (GBD) project systematically assesses mortality, healthy life expectancy, and disability across 195 countries and territories, using the disability-adjusted life year (DALY). Disability weights in the DALY are based upon surveys that ask users to rate health states based on lay descriptions. We conducted an experimental study to examine whether the inclusion or removal of psychological, social, or familial implications from a health state description might affect individual judgments about disease severity, and thus relative disability weights...
2018: PloS One
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