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hypertermia cancer

J A Dickson, M Suzangar
No abstract text is available yet for this article.
July 1973: British Journal of Cancer
G Robustelli della Cuna, P Pedrazzoli
The new anticancer agent lonidamine has been recently revisited for the treatment of various solid tumors, due to its peculiar and unusual mechanism of action (ie, interference with energy metabolism of tumor cells, morphologically displayed by the appearance of "condensed mitochondria"). First generation trials have in fact demonstrated therapeutic activity and an unusual toxicity profile. Lonidamine is devoid of conventional side effects induced by antiproliferative agents (ie, myelosuppression, stomatitis, cystitis, alopecia, renal, hepatic, and cardiac toxicity)...
April 1991: Seminars in Oncology
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