keyword
MENU ▼
Read by QxMD icon Read
search

Giu

keyword
https://www.readbyqxmd.com/read/28707094/primary-and-secondary-percutaneous-ureteral-stent-placement-comparison-of-stent-patency-and-clinical-outcome
#1
Seo Yeon Youn, Jung Suk Oh, Hae Giu Lee, Byung Gil Choi, Ho Jong Chun, Eu Hyun Kim
OBJECTIVES: To compare early double J ureteral stent (DJUS) dysfunction rate and long-term patency between two percutaneous ureteral stent placement methods: single-stage (primary) or two-stage (secondary) procedures. METHODS: A total of 250 (176 primary and 74 secondary) DJUS placements performed on interventional unit were retrospectively reviewed between February 2008 and March 2014. Early DJUS dysfunction was defined as no passage of contrast media into the urinary bladder in 2-3 days after placement...
July 13, 2017: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/28675315/a-novel-solid-self-nanoemulsifying-drug-delivery-system-s-snedds-for-improved-stability-and-oral-bioavailability-of-an-oily-drug-1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol
#2
Kyeong Soo Kim, Eun Su Yang, Dong Shik Kim, Dong Wuk Kim, Hye Hyun Yoo, Chul Soon Yong, Yu Seok Youn, Kyung Taek Oh, Jun-Pil Jee, Jong Oh Kim, Sung Giu Jin, Han Gon Choi
To develop a novel solid self-nanoemulsifying drug delivery system (S-SNEDDS) for a water-insoluble oily drug, 1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol (PLAG) with improved stability and oral bioavailability, numerous S-SNEDDS were prepared with surfactant, hydrophilic polymer, antioxidant, and calcium silicate (porous carrier) using the spray-drying method. Their physicochemical properties were evaluated using emulsion droplet size analysis, SEM and PXRD. Moreover, the solubility, dissolution, stability, and pharmacokinetics of the selected S-SNEDDS were assessed compared with the drug and a commercial soft capsule...
November 2017: Drug Delivery
https://www.readbyqxmd.com/read/28618419/addictive-potential-of-internet-applications-and-differential-correlates-of-problematic-use-in-internet-gamers-versus-generalized-internet-users-in-a-representative-sample-of-adolescents
#3
Tabea Rosenkranz, Kai W Müller, Michael Dreier, Manfred E Beutel, Klaus Wölfling
AIMS: This paper examines the addictive potential of 8 different Internet applications, distinguishing male and female users. Moreover, differential correlates of problematic use are investigated in Internet gamers (IG) and generalized Internet users (GIU). METHOD: In a representative sample of 5,667 adolescents aged 12-19 years, use of Internet applications, problematic Internet use, psychopathologic symptoms (emotional problems, hyperactivity/inattention, and psychosomatic complaints), personality (conscientiousness and extraversion), psychosocial correlates (perceived stress and self-efficacy), and coping strategies were assessed...
2017: European Addiction Research
https://www.readbyqxmd.com/read/28612675/formulation-of-novel-dry-powder-inhalation-for-fluticasone-propionate-and-salmeterol-xinafoate-with-capsule-based-device
#4
Kyeong Soo Kim, Jeong Hyun Kim, Sung Giu Jin, Dong Wuk Kim, Jong Oh Kim, Chul Soon Yong, Yu Seok Youn, Kyung Taek Oh, Jong Soo Woo, Han-Gon Choi
The aim of this study was to develop a novel fluticasone propionate (FP) and salmeterol xinafoate (SX)-loaded dry powder inhaler (DPI) system, which was composed of powder formulation and performance. The air flow resistances were determined with various types of DPI device, showing that the modified RS01 device gave the specific resistance similar to the commercial DPI device. The particle properties of fluticasone propionate (FP), salmeterol xinafoate (SX) and inhalation grade lactose particles, such as particle size, size distribution and fine content, were assessed...
June 14, 2017: Pharmaceutical Development and Technology
https://www.readbyqxmd.com/read/28324691/comparison-of-three-different-types-of-cilostazol-loaded-solid-dispersion-physicochemical-characterization-and-pharmacokinetics-in-rats
#5
Omer Mustapha, Kyung Soo Kim, Shumaila Shafique, Dong Shik Kim, Sung Giu Jin, Youn Gee Seo, Yu Seok Youn, Kyung Taek Oh, Chul Soon Yong, Jong Oh Kim, Han-Gon Choi
The aim of this research was to compare three different types of cilostazol-loaded solid dispersion system including solvent-evaporated, solvent-wetted and surface-attached solid dispersion. The effect of polymers and surfactants on the aqueous solubility of cilostazol was investigated, leading to the selection of polyvinylpyrrolidone (PVP) and sodium lauryl sulphate (SLS). Employing a spray-drying technique, numerous surface-attached, solvent-evaporated and solvent-wetted solid dispersions were prepared with various amounts PVP and SLS using water, 90% ethanol and acetone, respectively...
June 1, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/28224311/prevalence-incidence-and-sex-ratio-of-transsexualism-in-the-autonomous-region-of-madrid-spain-according-to-healthcare-demand
#6
Antonio Becerra-Fernández, José Miguel Rodríguez-Molina, Nuria Asenjo-Araque, María Jesús Lucio-Pérez, Miguel Cuchí-Alfaro, Eduardo García-Camba, Gilberto Pérez-López, Miriam Menacho-Román, María Carmen Berrocal-Sertucha, Domingo Ly-Pen, María Victorina Aguilar-Vilas
In recent years, different studies have provided estimates of the prevalence of transsexualism with very diverse results. The purpose of this study was to ascertain the prevalence, incidence, and sex ratio of transsexualism in the autonomous region of Madrid (Spain). A total of 1234 patients who attended from 2007 to the end of 2015 in the only Gender Identity Unit (GIU) in Madrid were analyzed. Sixty-three patients were excluded for various reasons; thus, 1171 could be included: 803 male-to-female (MtF) and 368 female-to-male (FtM) transsexual patients...
February 21, 2017: Archives of Sexual Behavior
https://www.readbyqxmd.com/read/27976506/uspio-enhanced-lymph-node-mri-using-3d-multi-echo-gre-in-a-rabbit-model
#7
Sung Hun Kim, Soon Nam Oh, Hyun Seok Choi, Hyun Sil Lee, Jaeseop Jun, Yoonho Nam, Sung Hak Lee, Jin-Kwon Lee, Hae Giu Lee
Ultrasmallsuperparamagnetic iron oxide (USPIO) has been suggested to be a negative MR contrast agent to detect metastatic lymph nodes. Previously reported studies have evaluated the diagnostic performance of USPIO-enhanced MR lymph node imaging based on signal intensity. In this study, we investigate the specific performance of three different parametric approaches (normalized signal intensity, R2 * and susceptibility) using 3D multi-echo gradient echo to quantify the USPIO particles in lymph nodes. Nine rabbits with VX2 tumor implants were scanned before and after USPIO injection...
November 2016: Contrast Media & Molecular Imaging
https://www.readbyqxmd.com/read/27918966/development-of-novel-cilostazol-loaded-solid-snedds-using-a-spg-membrane-emulsification-technique-physicochemical-characterization-and-in-vivo-evaluation
#8
Omer Mustapha, Kyung Soo Kim, Shumaila Shafique, Dong Shik Kim, Sung Giu Jin, Youn Gee Seo, Yu Seok Youn, Kyung Taek Oh, Beom-Jin Lee, Young Joon Park, Chul Soon Yong, Jong Oh Kim, Han-Gon Choi
The objective of this study was to develop a novel solid self-nanoemulsifying drug delivery system (SNEDDS) using a membrane emulsification technique involving Shirasu porous glass (SPG) which produced very small and uniform emulsion droplets, resulting in enhanced solubility, dissolution and oral bioavailability of poorly water-soluble cilostazol. The effects of carriers on the drug solubility were assessed, and pseudo-ternary phase diagrams were plotted. Among the liquid SNEDDS formulations tested, the liquid SNEDDS composed of peceol (oil), Tween 20 (surfactant) and Labrasol (cosurfactant) at a weight ratio of 15/55/30, produced the smallest emulsion droplet size...
February 1, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/27864610/the-monorail-technique-to-overcome-difficult-anatomical-course-during-implantation-of-central-venous-port-via-the-left-internal-jugular-vein
#9
Eu Hyun Kim, Jung Suk Oh, Ho Jong Chun, Hae Giu Lee, Byung Gil Choi
PURPOSE: The study aimed to introduce a monorail technique to overcome difficult anatomical course via left internal jugular vein in implantable port insertion. METHODS: From 2007 to 2016, a total of 9346 patients were referred for implantable port insertion in our interventional unit, among which 79 cases were requested to insert on the left side. Our monorail technique was applied only when the technical challenge of the catheter tip entering the azygos vein instead of the superior vena cava occurred (n = 7)...
March 2017: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/27518457/development-of-a-novel-l-sulpiride-loaded-quaternary-microcapsule-effect-of-tpgs-as-an-absorption-enhancer-on-physicochemical-characterization-and-oral-bioavailability
#10
Dong Shik Kim, Dong Wuk Kim, Kyeong Soo Kim, Jong Seo Choi, Youn Gee Seo, Yu Seok Youn, Kyung Taek Oh, Chul Soon Yong, Jong Oh Kim, Sung Giu Jin, Han-Gon Choi
The aim of this study was to assess the effect of d-α-tocopheryl polyethylene glycol 1000 succinate (TPGS) on the physicochemical characterization and oral bioavailability of a novel l-sulpiride-loaded quaternary microcapsule (QMC). The effect of carriers on drug solubility was investigated. Among the carriers tested, polyvinyl pyrrolidone (PVP), sodium lauryl sulphate (SLS) and TPGS were selected as polymer, surfactant and absorption enhancer, respectively, due to their high drug solubility. Using the solvent evaporation method, numerous QMCs with different ratios of l-sulpiride, PVP, SLS and TPGS were prepared, and their physicochemical properties, solubility and release were evaluated...
November 1, 2016: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/27451362/development-of-novel-prasugrel-base-microsphere-loaded-tablet-with-enhanced-stability-physicochemical-characterization-and-in-vivo-evaluation-in-beagle-dogs
#11
Kyeong Soo Kim, Jin Cheul Kim, Sung Giu Jin, Dong Wuk Kim, Dong Shik Kim, Chul Soon Yong, Jong Oh Kim, Yu Seok Youn, Kyung Taek Oh, Jong Soo Woo, Han-Gon Choi
The objective of this study was to develop a novel prasugrel base microsphere-loaded tablet (PBMST) with enhanced stability as a bioequivalent to the commercial prasugrel hydrochloride-loaded tablet. Numerous prasugrel base-loaded microspheres were prepared with hydroxypropylmethyl cellulose (HPMC), colloidal silica and various acidifying agents using a spray-drying process, and the physicochemical properties, solubility and stability were investigated. The PBMSTs were prepared and their dissolution, pharmacokinetics in beagle dogs and stability were evaluated compared to commercial prasugrel hydrochloride-loaded tablets...
October 1, 2016: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/27397868/comparison-of-solvent-wetted-and-kneaded-l-sulpiride-loaded-solid-dispersions-powder-characterization-and-in-vivo-evaluation
#12
COMPARATIVE STUDY
Dong Shik Kim, Jong Seo Choi, Dong Wuk Kim, Kyeong Soo Kim, Youn Gee Seo, Kwan Hyung Cho, Jong Oh Kim, Chul Soon Yong, Yu Seok Youn, Soo-Jeong Lim, Sung Giu Jin, Han-Gon Choi
The purpose of this study was to compare the powder properties, solubility, dissolution and oral absorption of solvent-wetted (SWSD) and kneaded (KNSD) l-sulpiride-loaded solid dispersions. The SWSD and KNSD were prepared with silicon dioxide, sodium laurylsulfate and D-α-tocopheryl polyethylene glycol 1000 succinate (TPGS) using a spray dryer and high shear mixer, respectively. Their powder properties, solubility, dissolution and oral absorption were assessed compared to l-sulpiride powder. The drug in SWSD was in the amorphous state; however, in KNSD, it existed in the crystalline state...
September 10, 2016: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/27127576/transjugular-intrahepatic-portosystemic-shunt-occlusion-complicated-with-biliary-fistula-successfully-treated-with-a-stent-graft-a-case-report
#13
Eunyoung Kim, Sung Won Lee, Woo Hyeon Kim, Si Hyun Bae, Nam Ik Han, Jung Suk Oh, Ho Jong Chun, Hae Giu Lee
A 43-year-old man with liver cirrhosis received transjugular intrahepatic portosystemic shunt (TIPS) for the treatment of recurrent variceal bleeding and F3 esophageal varices. During routine follow up liver ultrasound examination, six months after the implantation, TIPS occlusion was suspected and TIPS revision was performed. During the revision, moderate to severe stenosis at the hepatic venous segment of the tract and a total occlusion at the parenchymal segment of TIPS tract near the portal vein with biliary-TIPS fistula were identified with a clear visualization of the common bile duct...
January 2016: Iranian Journal of Radiology: a Quarterly Journal Published By the Iranian Radiological Society
https://www.readbyqxmd.com/read/27106527/effect-of-hm30181-mesylate-salt-loaded-microcapsules-on-the-oral-absorption-of-paclitaxel-as-a-novel-p-glycoprotein-inhibitor
#14
Jin Cheul Kim, Kyeong Soo Kim, Dong Shik Kim, Sung Giu Jin, Dong Wuk Kim, Yong Il Kim, Jae-Hyun Park, Jong Oh Kim, Chul Soon Yong, Yu Seok Youn, Jong Soo Woo, Han-Gon Choi
The purpose of this study was to develop HM30181 mesylate salt (HM30181M)-loaded microcapsules as a novel P-glycoprotein inhibitor for enhancing the oral absorption of paclitaxel. The effect of various carriers including hydrophilic polymers and solvents on the solubility of HM30181M were evaluated. Among the hydrophilic polymers and solvents tested, HPMC and methylene chloride (and ethanol) provided the highest HM30181M solubility. Numerous HM30181M-loaded microcapsules were prepared with HPMC, silicon dioxide and acidifying agents using a spray-drying technique, and their solubility, dissolution and physicochemical properties were evaluated...
June 15, 2016: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/27083204/a-side-hole-catheter-for-catheterization-of-a-difficult-internal-mammary-artery
#15
Jung Suk Oh, Byung Gil Choi, Ho Jong Chun, Hae Giu Lee
Background The internal mammary artery (IMA) can be a source of hemoptysis in patients with chronic lung disease. Intervention via the IMA can be a challenge due to anatomic variations and lead to excessive contrast use and radiation exposure. Purpose To evaluate safety and efficiency of a new side-hole catheter for the catheterization of the IMA in patients with hemoptysis. Material and Methods From January 2011 to August 2014, a total of 96 transarterial embolization procedures required exact evaluation of the IMA due to chronic lung disease involving the anterior thorax...
March 2017: Acta Radiologica
https://www.readbyqxmd.com/read/26992922/effect-of-magnesium-carbonate-on-the-solubility-dissolution-and-oral-bioavailability-of-fenofibric-acid-powder-as-an-alkalising-solubilizer
#16
Kyeong Soo Kim, Jeong Hyun Kim, Sung Giu Jin, Dong Wuk Kim, Dong Shik Kim, Jong Oh Kim, Chul Soon Yong, Kwan Hyung Cho, Dong Xun Li, Jong Soo Woo, Han-Gon Choi
To investigate the possibility of developing a novel oral pharmaceutical product using fenofibric acid instead of choline fenofibrate, the powder properties, solubility, dissolution and pharmacokinetics in rats of fenofibrate, choline fenofibrate and fenofibric acid were compared. Furthermore, the effect of magnesium carbonate, an alkalising agent on the solubility, dissolution and oral bioavailability of fenofibric acid was assessed, a mixture of fenofibric acid and magnesium carbonate being prepared by simple blending at a weight ratio of 2/1...
April 2016: Archives of Pharmacal Research
https://www.readbyqxmd.com/read/26983932/novel-montelukast-sodium-loaded-stable-oral-suspension-bioequivalent-to-the-commercial-granules-in-rats
#17
Dong Wuk Kim, Young Hun Kim, Abid Mehmood Yousaf, Dong Shik Kim, Taek Kwan Kwon, Jung Hee Park, Yong Il Kim, Jae-Hyun Park, Sung Giu Jin, Kyung Soo Kim, Kwan Hyung Cho, Dong Xun Li, Jong Oh Kim, Chul Soon Yong, Jong Soo Woo, Han-Gon Choi
To develop a montelukast sodium-loaded stable oral suspension bioequivalent to the commercial granules in rats, several montelukast sodium-loaded suspensions were prepared with a suspending agent, stabilizers and anti-aggregation agents, and their stabilities were investigated by visually observing the sedimentation phenomenon and determining the concentration of the degradation product. Moreover, dissolution and pharmacokinetic studies of the optimized formulation were examined in rats compared to commercial montelukast sodium-loaded granules...
April 2016: Archives of Pharmacal Research
https://www.readbyqxmd.com/read/26960538/safety-of-gadobutrol-in-over-23-000-patients-the-gardian-study-a-global-multicentre-prospective-non-interventional-study
#18
MULTICENTER STUDY
Martin R Prince, Hae Giu Lee, Chang-Hee Lee, Sung Won Youn, In Ho Lee, Woong Yoon, Benqiang Yang, Haiping Wang, Jin Wang, Tiffany Ting-Fang Shih, Guo-Shu Huang, Jiing-Feng Lirng, Petra Palkowitsch
OBJECTIVES: To investigate the safety and tolerability of gadobutrol at the recommended dose in patients requiring contrast-enhanced magnetic resonance imaging/angiography (MRI/MRA) in the routine setting. METHODS: GARDIAN prospectively enrolled 23,708 patients undergoing routine gadobutrol-enhanced MRI/MRA for approved indications at 272 study centres in Europe, Asia, North America, and Africa and monitored for adverse events. RESULTS: Median gadobutrol dose was 0...
January 2017: European Radiology
https://www.readbyqxmd.com/read/26851354/influence-of-hydrophilic-polymers-on-functional-properties-and-wound-healing-efficacy-of-hydrocolloid-based-wound-dressings
#19
Sung Giu Jin, Abid Mehmood Yousaf, Kyeong Soo Kim, Dong Wuk Kim, Dong Shik Kim, Jin Ki Kim, Chul Soon Yong, Yu Seok Youn, Jong Oh Kim, Han-Gon Choi
The purpose of this study was to investigate the influence of different hydrophilic polymers on the swelling, bioadhesion and mechanical strength of hydrocolloid wound dressings (HCDs) in order to provide an appropriate composition for a hydrocolloid wound dressing system. In this study, the HCDs were prepared with styrene-isoprene-styrene copolymer (SIS) and polyisobutylene (PIB) as the base using a hot melting method. Additionally, numerous SIS/PIB-based HCDs were prepared with six hydrophilic polymers, and their wound dressing properties were assessed...
March 30, 2016: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/26834471/novel-electrosprayed-nanospherules-for-enhanced-aqueous-solubility-and-oral-bioavailability-of-poorly-water-soluble-fenofibrate
#20
Abid Mehmood Yousaf, Omer Mustapha, Dong Wuk Kim, Dong Shik Kim, Kyeong Soo Kim, Sung Giu Jin, Chul Soon Yong, Yu Seok Youn, Yu-Kyoung Oh, Jong Oh Kim, Han-Gon Choi
PURPOSE: The purpose of the present research was to develop a novel electrosprayed nanospherule providing the most optimized aqueous solubility and oral bioavailability for poorly water-soluble fenofibrate. METHODS: Numerous fenofibrate-loaded electrosprayed nanospherules were prepared with polyvinylpyrrolidone (PVP) and Labrafil(®) M 2125 as carriers using the electrospray technique, and the effect of the carriers on drug solubility and solvation was assessed...
2016: International Journal of Nanomedicine
keyword
keyword
95090
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"