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https://www.readbyqxmd.com/read/29667940/the-importance-of-the-saphenous-nerve-block-for-analgesia-following-major-ankle-surgery-a-randomized-controlled-double-blind-study
#1
Siska Bjørn, Wan Yi Wong, Jørgen Baas, Kristian K Nielsen, Jens Børglum, Rasmus Wulff Hauritz, Thomas Fichtner Bendtsen
BACKGROUND AND OBJECTIVES: Major ankle surgery causes intense postoperative pain, and whereas the importance of a sciatic nerve block is well established, the clinical significance of a supplemental saphenous nerve block has never been determined in a prospective, randomized, double-blind, placebo-controlled trial. We hypothesized that a saphenous nerve block reduces the proportion of patients experiencing significant clinical pain after major ankle surgery. METHODS: Eighteen patients were enrolled and received a popliteal sciatic nerve block...
March 26, 2018: Regional Anesthesia and Pain Medicine
https://www.readbyqxmd.com/read/29667939/a-photochemical-approach-for-a-fast-and-self-limited-covalent-modification-of-surface-supported-graphene-with-photoactive-dyes
#2
Natalia Sergeeva, Alexander N Chaika, Brian Walls, Barry Murphy, Killian Walshe, David Martin, Billy D O Richards, Gin Jose, K Fleischer, Victor Aristov, Olga Molodtsova, Igor V Shvets, Sergey Krasnikov
Herein, we report a simple method for a covalent modification of surface-supported graphene with photoactive dyes. Graphene was fabricated on cubic-SiC/Si(001) wafers due to their low cost and suitability for mass-production of continuous graphene fit for electronic applications on millimetre scale. Functionalisation of the graphene surface was carried out in solution via white light-induced photochemical generation of phenazine radicals from phenazine diazonium salt. The resulting covalently bonded phenazine-graphene hybrid structure was characterised by scanning tunnelling microscopy (STM) and spectroscopy (STS), Raman spectroscopy and density functional theory (DFT) calculations...
April 18, 2018: Nanotechnology
https://www.readbyqxmd.com/read/29667933/a-cbct-study-of-the-gravity-induced-movement-in-rotating-rabbits
#3
Jeffrey Barber, Chun-Chien Shieh, William Counter, Jonathan R Sykes, Peter Bennett, Verity Ahern, Stéphanie Corde, Soo-Min Heng, Paul White, Michael Jackson, Paul Liu, Paul J Keall, Ilana Feain
Fixed-beam radiotherapy systems with subjects rotating about a longitudinal (horizontal) axis are subject to gravity-induced motion. Limited reports on the degree of this motion, and any deformation, has been reported previously. The purpose of this study is to quantify the degree of anatomical motion caused by rotating a subject around a longitudinal axis, using cone-beam CT (CBCT). 
 
 In the current study, a purpose-made longitudinal rotating was aligned to a Varian TrueBeam kV imaging system...
April 18, 2018: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/29667904/establishing-cut-offs-for-urine-erythrocyte-and-leukocyte-dipstick-tests
#4
Yousun Chung, Dae-Hyun Ko, Jungwon Hyun, Hyun Soo Kim, Min-Jeong Park, Dong Hoon Shin
Urine erythrocyte (Ery) and leukocyte (Leu) dipstick tests are essential for detecting microhematuria and urinary tract infection. Currently, there is no suggestion for establishing the cut-off limits in an ordinal scale test. This study aimed to establish the cut-off limits for urine Ery and Leu dipstick tests via probit regression. From 1 January 2016 to 30 June 2016, laboratory data were collected from patients at one teaching hospital whose specimen had analytical results from both a urine dipstick test and an automated urine particle analyzer...
April 18, 2018: Scandinavian Journal of Clinical and Laboratory Investigation
https://www.readbyqxmd.com/read/29667845/development-of-an-instrument-to-assess-athletic-trainers-attitudes-toward-transgender-patients
#5
Kristine A Ensign, Brian M Dodge, Debra Herbenick, Carrie L Docherty
CONTEXT:   The unique contexts in which athletic trainers (ATs) work require specific tools in order to understand their attitudes toward diverse patient populations, including sexual and gender minorities. OBJECTIVE:   To develop and validate the Attitudes Toward Transgender Patients (ATTP) instrument for ATs. DESIGN:   Cross-sectional study. SETTING:   Semistructured interviews, paper-based questionnaire, and electronic questionnaire...
April 18, 2018: Journal of Athletic Training
https://www.readbyqxmd.com/read/29667836/molecular-dynamics-simulations-are-redefining-our-view-of-peptides-interacting-with-biological-membranes
#6
Jakob P Ulmschneider, Martin B Ulmschneider
Ever since the first molecular mechanics computer simulations of biological molecules became possible, there has been the dream to study all complex biological phenomena in silico, simply bypassing the enormous experimental challenges and their associated costs. For this, two inherent requirements need to be met: First, the time scales achievable in simulations must reach up to the millisecond range and even longer. Second, the computational model must accurately reproduce what is measured experimentally. Despite some recent successes, the general consensus in the field to date has been that neither of these conditions have yet been met and that the dream will be realized, if at all, only in the distant future...
April 18, 2018: Accounts of Chemical Research
https://www.readbyqxmd.com/read/29667835/oxygen-release-induced-chemomechanical-breakdown-of-layered-cathode-materials
#7
Linqin Mu, Ruoqian Lin, Rong Xu, Lili Han, Sihao Xia, Dimosthenis Sokaras, James Steiner, Tsu-Chien Weng, Dennis Nordlund, Marca M Doeff, Yijin Liu, Kejie Zhao, Huolin L Xin, Feng Lin
Chemical and mechanical properties interplay on the nanometric scale and collectively govern the functionalities of battery materials. Understanding the relationship between the two can inform the design of battery materials with optimal chemomechanical properties for long-life lithium batteries. Herein, we report a mechanism of nanoscale mechanical breakdown in layered oxide cathode materials, originating from oxygen release at high states of charge under thermal abuse conditions. We observe that the mechanical breakdown of charged Li1-xNi0...
April 18, 2018: Nano Letters
https://www.readbyqxmd.com/read/29667778/dna-methylation-biomarkers-for-the-occurrence-of-lung-adenocarcinoma-from-tcga-data-mining
#8
Xiao-Feng Zhu, Bi-Sheng Zhu, Fei-Ma Wu, Hai-Bo Hu
The development of lung cancer is a combination of multifactor, multistage, and multiple genetic alterations processes. DNA methylation is an important factor. Currently, the study on the genome-scale epigenetic modification for studying the pathogenesis of lung cancer is still lacking. Here, we aimed to identify the epigenetic modifications of lung cancer, thus to provide scientific basis for the personalized medicine, and research of classification screening for lung adenocarcinoma patients. The DNA methylation data, and the corresponding clinical information of lung adenocarcinoma samples were extracted from the Cancer Genome Atlas (TCGA) database...
April 18, 2018: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/29667758/synthesis-of-enantiomerically-enriched-drug-precursors-by-lactobacillus-paracasei-bd87e6-as-a-biocatalyst
#9
Selda Öksüz, Engin Şahin, Enes Dertli
Global sales of single enantiomeric drug products are growing at an alarming rate every year. A total of 7 bacterial strains were screened for their ability to reduce acetophenones to its corresponding alcohol. Among these strain Lactobacillus paracasei BD87E6 was found to be the most successful biocatalyst to reduce the ketones to the corresponding alcohols. The reaction conditions were systematically optimized for the reducing agent Lactobacillus paracasei BD87E6, which showed high enantioselectivity and conversion for the bioreduction...
April 18, 2018: Chemistry & Biodiversity
https://www.readbyqxmd.com/read/29667739/maternal-depressive-symptoms-during-and-after-pregnancy-and-child-developmental-milestones
#10
Soile Tuovinen, Marius Lahti-Pulkkinen, Polina Girchenko, Jari Lipsanen, Jari Lahti, Kati Heinonen, Rebecca M Reynolds, Esa Hämäläinen, Eero Kajantie, Hannele Laivuori, Anu-Katriina Pesonen, Pia M Villa, Katri Räikkönen
BACKGROUND: Maternal depressive symptoms during and after pregnancy predict poorer child neurodevelopment. The effects of timing, symptom severity, and additive influences remain unclear. METHODS: A total of 2,231 mothers of the Prediction and Prevention of Pre-eclampsia and Intrauterine Growth Restriction (PREDO) study completed the Center for Epidemiological Studies Depression Scale biweekly up to 14 times during pregnancy and twice up to 12 months after pregnancy...
April 18, 2018: Depression and Anxiety
https://www.readbyqxmd.com/read/29667703/diagnosis-and-management-practices-for-gestational-diabetes-mellitus-in-australia-cross-sectional-survey-of-the-multidisciplinary-team
#11
Nina Meloncelli, Adrian Barnett, Fiona Pelly, Susan de Jersey
BACKGROUND: Gestational diabetes mellitus (GDM) is one of the most common pregnancy disorders; however, if well managed, women with GDM experience similar pregnancy outcomes to those without. Currently, there is limited evidence on actual management practices across Australia or how multidisciplinary teams interact to optimise care. AIMS: To examine the current screening, diagnostic, task and role perceptions and management practices, as reported by members of the GDM multidisciplinary team...
April 18, 2018: Australian & New Zealand Journal of Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/29667700/irritability-and-parenting-styles-in-adolescents-with-attention-deficit-hyperactivity-disorder-a-controlled-study
#12
Halit Necmi Uçar, Ayşe Pınar Vural
Attention-deficit/hyperactivity disorder (ADHD) affects functioning of the family, decreasing interactions and loyalty and increasing conflict between adolescents with ADHD and their families. Irritable mood and difficulties with emotional dysregulation are common in children with ADHD. The objective of the current study was to assess levels of irritability in adolescents with ADHD using self- and parent-report scales, and investigate the relationship between irritability levels and parental attitudes. A total of 47 adolescents with ADHD and 39 adolescents with typical development participated in the current study...
April 17, 2018: Journal of Psychosocial Nursing and Mental Health Services
https://www.readbyqxmd.com/read/29667676/functional-inks-and-printing-of-two-dimensional-materials
#13
REVIEW
Guohua Hu, Joohoon Kang, Leonard W T Ng, Xiaoxi Zhu, Richard C T Howe, Christopher G Jones, Mark C Hersam, Tawfique Hasan
Graphene and related two-dimensional materials provide an ideal platform for next generation disruptive technologies and applications. Exploiting these solution-processed two-dimensional materials in printing can accelerate this development by allowing additive patterning on both rigid and conformable substrates for flexible device design and large-scale, high-speed, cost-effective manufacturing. In this review, we summarise the current progress on ink formulation of two-dimensional materials and the printable applications enabled by them...
April 18, 2018: Chemical Society Reviews
https://www.readbyqxmd.com/read/29667647/can-job-control-ameliorate-work-family-conflict-and-enhance-job-satisfaction-among-chinese-registered-nurses-a-mediation-model
#14
Xiaotong Ding, Yajuan Yang, Dan Su, Ting Zhang, Lunlan Li, Huiping Li
BACKGROUND: Low job satisfaction is the most common cause of nurses' turnover and influences the quality of nursing service. Moreover, we have no idea regarding whether job control, as an individual factor, can play a role in the relationship. OBJECTIVE: To explore the relationship between work-family conflict and job satisfaction among Chinese registered nurses and the mediating role of job control in this relationship. METHODS: From August 2015 to November 2016, 487 Chinese registered nurses completed a survey...
April 2018: International Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/29667635/-the-application-of-the-biometriclal-dactylography-17-0-program-complex-for-the-digital-interpretation-of-the-finger-dermatoglyphic-features
#15
V N Zvyagin, V A Rakitin, E E Fomina
The objective of the present study was the development of the computer software for the scale-free interpretation of the finger dermatoglyphic features needed for the objective comprehensive evaluation of their principal characteristics in the digital terms. We have elaborated the program complex making it possible to address the following problems: thr formulation of the database of electronic copies of the finger print and toe print images in the family groups, the display of the finger print and toe print images on the screen, marking the points and lines for automated readout of digital angular and metric information or automated calculation of relative values, the formulation of the database of digital information about the papillary patterns on the fingers and toes in the family triplets (farther + mother + child) and its import into an Excel file...
2018: Sudebno-meditsinskaia Ekspertiza
https://www.readbyqxmd.com/read/29667570/barcoding-hybrids-heterogeneous-distribution-of-schistosoma-haematobium-%C3%A3-schistosoma-bovis-hybrids-across-the-senegal-river-basin
#16
Nele A M Boon, Frederik VAN DEN Broeck, Djiby Faye, Filip A M Volckaert, Souleymane Mboup, Katja Polman, Tine Huyse
ABSTRACTHybridization events between Schistosoma species (Digenea, Platyhelminthes) are reported with increasing frequency, largely due to improved access to molecular tools. Nevertheless, little is known about the distribution and frequency of hybrid schistosomes in nature. Screening for hybrids on a large scale is complicated by the need for nuclear and mitochondrial sequence information, precluding a 'simple' barcoding approach. Here we aimed to determine and understand the spatiotemporal distribution of Schistosoma haematobium × Schistosoma bovis hybrids in the Senegal River Basin...
April 18, 2018: Parasitology
https://www.readbyqxmd.com/read/29667547/new-markers-for-predicting-fertility-of-the-male-gametes-in-the-post-genomic-age
#17
Savina Dipresa, Luca De Toni, Carlo Foresta, Andrea Garolla
A number of test have been proposed to assess male fertility potential, ranging from routine testing by light microscopic method for evaluating semen samples, to screening test for DNA integrity aimed to look at sperm chromatin abnormalities. Spermatozoa are an extremely differentiated cell, they have critical functions for embryo development and heredity, in addiction to delivering a haploid paternal genome to the oocyte. Towards this goal certain requirements must always be met. The ability of spermatozoa to perform its reproductive function taking place in the spermatogenesis, a highly specialized process depending on multiple factors with effect on male fertility...
April 18, 2018: Protein and Peptide Letters
https://www.readbyqxmd.com/read/29667507/effect-of-inspiratory-muscle-training-imt-on-aerobic-capacity-respiratory-muscle-strength-and-rate-of-perceived-exertion-in-paraplegics
#18
Sonali Soumyashree, Jaskirat Kaur
OBJECTIVES: The purpose is to study the effect of inspiratory muscle training on aerobic capacity, respiratory muscle strength and rate of perceived exertion in paraplegics. STUDY DESIGN: Randomized controlled trial. SETTINGS: Rehabilitation department in Indian Spinal Injuries Centre, New Delhi. PARTICIPANTS: A sample of 30 paraplegics (T1-T12) were randomly allocated into two groups: inspiratory muscle training (IMT) group and control group...
April 18, 2018: Journal of Spinal Cord Medicine
https://www.readbyqxmd.com/read/29667491/optimization-of-3d-print-material-for-the-recreation-of-patient-specific-temporal-bone-models
#19
Max Haffner, Austin Quinn, Tsung-Yen Hsieh, E Bradley Strong, Toby Steele
OBJECTIVE: Identify the 3D printed material that most accurately recreates the visual, tactile, and kinesthetic properties of human temporal bone Subjects and Methods: Fifteen study participants with an average of 3.6 years of postgraduate training and 56.5 temporal bone (TB) procedures participated. Each participant performed a mastoidectomy on human cadaveric TB and five 3D printed TBs of different materials. After drilling each unique material, participants completed surveys to assess each model's appearance and physical likeness on a Likert scale from 0 to 10 (0 = poorly representative, 10 = completely life-like)...
May 2018: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/29667477/return-to-work-after-severe-traumatic-brain-injury-a-national-study-with-a-one-year-follow-up-of-neurocognitive-and-behavioural-outcomes
#20
Solrun Sigurdardottir, Nada Andelic, Eike Wehling, Audny Anke, Toril Skandsen, Oyvor Oistensen Holthe, Unn Sollid Manskow, Cecilie Roe
The objectives were to investigate the frequency of return-to-work (RTW) one year after severe traumatic brain injury (sTBI: Glasgow Coma Scale, GCS 3-8) and to identify which demographic and injury-related characteristics and neurocognitive factors are associated with RTW. This study is part of a prospective national study on sTBI conducted in all four Norwegian Trauma Referral Centres, including patients aged >15 years over a period of three years (n = 378). For the purpose of this study, only pre-employed individuals of working age (16 to 67 years) were investigated for RTW (n = 143), and of these, 104 participants underwent neuropsychological testing...
April 18, 2018: Neuropsychological Rehabilitation
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