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https://www.readbyqxmd.com/read/29763345/tissue-engineering-of-necrotic-dental-pulp-of-immature-teeth-with-apical-periodontitis-in-dogs-radiographic-and-histological-evaluation
#1
Eman A El Ashiry, Najlaa M Alamoudi, Mahmoud K El Ashiry, Hagar A Bastawy, Douaa A El Derwi, Hazem M Atta
AIM: To evaluate tissue engineering technology to regenerate pulp-dentin like tissues in pulp canals of immature necrotic permanent teeth with apical periodontitis in dogs. STUDY DESIGN: The study was performed on 36 teeth in 12 dogs. The experiment was carried out using split mouth design. In each dog 3 teeth were selected for implementing the study procedure. Apical periodontitis was induced in Group A and B teeth. Group (A): immature upper left 2nd permanent incisors that were transplanted with a construct of autologous dental pulp stem cells with growth factors seeded in a chitosn hydrogel scaffold...
May 15, 2018: Journal of Clinical Pediatric Dentistry
https://www.readbyqxmd.com/read/29762318/endoscopically-assisted-modified-caldwell-luc-approach-to-enucleation-of-dentigerous-cyst-with-ectopic-tooth-from-the-maxillary-sinus
#2
Isaac Liau, Nicholas Lynch, Brenton Hearn, Andrew Cheng
Dentigerous cysts in the craniomaxillofacial complex are a benign pathology commonly associated with ectopically placed teeth. Owing to slow and asymptomatic growth, they often attain considerable size before diagnosis that may compromise adjacent anatomical structures. Various techniques for removal of dentigerous cysts from the maxillary sinus have been described. This case report demonstrates a hybrid endoscopically assisted modification of the Caldwell-Luc approach to provide the technical advantages of both techniques...
May 14, 2018: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29760819/antibacterial-and-anti-inflammatory-potential-of-morus-alba-stem-extract
#3
Ichaya Yiemwattana, Niratcha Chaisomboon, Kusuma Jamdee
Background: Periodontitis, a chronic inflammatory disease, is the leading cause of tooth loss in adults. Evidence for the anti inflammatory activity of M. alba Stem Extract (MSE) in periodontal disease is limited. Objective: The study aimed to investigate the inhibitory effect of MSE on the growth of periodontopathic bacteria and expression of interleukin (IL)-6 and IL-8 in Porphyromonas gingivalis Lipopolysaccharide (LPS)-stimulated human Periodontal Ligament (hPDL) fibroblasts...
2018: Open Dentistry Journal
https://www.readbyqxmd.com/read/29752201/maxillary-tooth-growth-in-the-adult-male-babirusa-genus-babyrousa
#4
Alastair A Macdonald, Darren J Shaw
The growth of the maxillary canine teeth of the babirusa (genus Babyrousa) was studied on a sample of 149 adult male babirusa skulls from twenty-two international museum and private collections. Skulls from Buru, Sulawesi and the Togian Islands were represented. The continuous growth process was summarised into five stages ('A'-'E') according to the position of the tip of the tooth over the bones of the skull. The supracutaneous portion of the tooth grew in a curve-linear fashion dorso-caudally, and was orientated such that the tips grew towards the midline of the cranium...
May 8, 2018: Comptes Rendus Biologies
https://www.readbyqxmd.com/read/29745816/the-unique-biomineralization-transcriptome-and-proteome-of-lytechinus-variegatus-teeth
#5
Keith Alvares, Caroline J DeHart, Paul M Thomas, Neil L Kelleher, Arthur Veis
BACKGROUND: Matrix-regulated biomineralization involves the specific nucleation and growth of mineral phases within or upon preformed structured organic matrices. We hypothesized that there might be a general mechanism whereby anionic, phosphorylated mineral ion-binding proteins assist in specifically locating the mineral ions with respect to the mineralizing structural organic matrix. Here we extended these studies to invertebrate mineralization in Lytechinus variegatus (Lv) teeth. MATERIALS AND METHODS: The tooth proteins were extracted and the phosphoproteins occluded in the mineral were enriched by passage through a ProQ Diamond phosphoprotein enrichment column, and subjected to MS/MS analysis...
December 2018: Connective Tissue Research
https://www.readbyqxmd.com/read/29734801/regenerative-endodontics-after-front-tooth-trauma-a-case-report
#6
Renzo Bassetti, Johannes Kuttenberger, Mario Bassetti
In the context of tooth trauma, mostly the maxillary central front teeth are involved, whereby their roots are in some cases still in the developing stage (immature). Depending on the type of trauma, a necrosis of the pulp is the consequence or at least foreseeable. In order to preserve such a tooth, an endodontic therapy is inevitable. The disadvantage of conventional endodontic therapy methods of immature teeth (apexification, apexogenesis) is the root growth stop. Alternatively, the regeneration/revascularisation of the dental pulp (RP) was suggested, that allows a further root growth...
May 14, 2018: Swiss Dental Journal
https://www.readbyqxmd.com/read/29722897/mucopolysaccharidosis-vi-and-effects-on-growth-of-the-apical-bases-a-case-report
#7
Moema Ferreira Dos Reis, Lucas Rodrigues Pinheiro, Maria das Graças Rodrigues Pinheiro, Haroldo Amorim de Almeida, Patrícia do Socorro Queiroz Feio, Sâmia Cordovil de Almeida, Isabel Cristina Neves de Souza, Roberto Giugliani, Ida Vanessa Doederlein Schwartz, Rosely Maria Dos Santos Cavaleiro, João de Jesus Viana Pinheiro, Luiz Carlos Santana da Silva
OBJECTIVE: Mucopolysaccharidosis (MPS) VI is a rare disorder caused by an autosomal recessive mutation in the short arm of chromosome 5 (5q12-13) leading to an N-acetylgalactosamine-sulfatase lysosomal enzyme deficiency and numerous systemic clinical changes. The oral and maxillofacial complex may exhibit tooth eruption anomalies, macroglossia, gingival hypertrophy, mouth breathing, increased lower facial height, open bite, retrognathia, and progressive TMJ arthrosis. This report describes craniofacial growth changes in two MPS VI patients, sisters and daughters of outbred parents, who were longitudinally monitored from 11 to 15 years of age...
May 3, 2018: Special Care in Dentistry
https://www.readbyqxmd.com/read/29720330/cervical-vertebrae-maturation-a-blinded-trial-study
#8
A Lucchese, G Caldara, L Montebugnoli, G Ghilardi, F Toma, A Deregibus, M Manuelli
This blinded trial was conducted to analyze possible correlations between the cervical vertebrae maturation method (CVM) and the mineralization of mandibular teeth as described by Demirjian et al. (TMS). Panoramic and cephalometric radiographs of 500 orthodontic patients were analyzed by two blinded operators. TMS was utilized to analyze mineralization of second molar, second and first premolar and canine on the left side of the mandible; CVM stage was also evaluated. A blinded statistician performed statistical correlations and multiple regression analysis...
March 2018: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/29720250/efficient-induction-of-functional-ameloblasts-from-human-keratinocyte-stem-cells
#9
Xuefeng Hu, Jyh-Wei Lee, Xi Zheng, Junhua Zhang, Xin Lin, Yingnan Song, Bingmei Wang, Xiaoxiao Hu, Hao-Hueng Chang, Yiping Chen, Chun-Pin Lin, Yanding Zhang
BACKGROUND: Although adult human tissue-derived epidermal stem cells are capable of differentiating into enamel-secreting ameloblasts and forming teeth with regenerated enamel when recombined with mouse dental mesenchyme that possesses odontogenic potential, the induction rate is relatively low. In addition, whether the regenerated enamel retains a running pattern of prism identical to and acquires mechanical properties comparable with human enamel indeed warrants further study. METHODS: Cultured human keratinocyte stem cells (hKSCs) were treated with fibroblast growth factor 8 (FGF8) and Sonic hedgehog (SHH) for 18 h or 36 h prior to being recombined with E13...
May 2, 2018: Stem Cell Research & Therapy
https://www.readbyqxmd.com/read/29714701/delayed-tooth-reimplantation-with-4-year-follow-up-the-management-of-ankylosis-during-facial-growth
#10
Franciny Querobim Ionta, Priscilla Santana Pinto Gonçalves, Heitor Marques Honório, Gabriela Cristina de Oliveira, Catarina Ribeiro Barros de Alencar, Natália Mello Santos, Thais Marchini de Oliveira, Daniela Rios
This case report describes the consequences of delayed (24 hours) reimplantation of an avulsed maxillary central incisor, findings over a 4-year follow-up period, and the management of ankylosis during facial growth. After a traumatic event, a 10-year-old boy was taken to a hospital emergency department due to injuries to his face, including avulsion of the maxillary left central incisor. Despite the short amount of time before arriving at the hospital (10 minutes) and use of the correct storage medium (milk), the tooth was not reimplanted, and the parents did not receive instructions to seek dental treatment...
May 2018: General Dentistry
https://www.readbyqxmd.com/read/29713351/the-role-of-fibroblast-growth-factors-in-tooth-development-and-incisor-renewal
#11
REVIEW
Wen Du, Wei Du, Haiyang Yu
The mineralized tissue of the tooth is composed of enamel, dentin, cementum, and alveolar bone; enamel is a calcified tissue with no living cells that originates from oral ectoderm, while the three other tissues derive from the cranial neural crest. The fibroblast growth factors (FGFs) are critical during the tooth development. Accumulating evidence has shown that the formation of dental tissues, that is, enamel, dentin, and supporting alveolar bone, as well as the development and homeostasis of the stem cells in the continuously growing mouse incisor is mediated by multiple FGF family members...
2018: Stem Cells International
https://www.readbyqxmd.com/read/29709292/patterns-of-lateral-enamel-growth-in-homo-naledi-as-assessed-through-perikymata-distribution-and-number
#12
Debbie Guatelli-Steinberg, Mackie C O'Hara, Adeline Le Cabec, Lucas K Delezene, Donald J Reid, Matthew M Skinner, Lee R Berger
Perikymata, incremental growth lines visible on tooth enamel surfaces, differ in their distribution and number among hominin species, although with overlapping patterns. This study asks: (1) How does the distribution of perikymata along the lateral enamel surface of Homo naledi anterior teeth compare to that of other hominins? (2) When both perikymata distribution and number are analyzed together, how distinct is H. naledi from other hominins? A total of 19 permanent anterior teeth (incisors and canines) of H...
April 27, 2018: Journal of Human Evolution
https://www.readbyqxmd.com/read/29708396/evaluation-of-characteristics-of-the-craniofacial-complex-and-dental-maturity-in-girls-with-central-precocious-puberty
#13
Hee-Kyung Lee, Sung-Hwan Choi, Dong Fan, Kyung-Mi Jang, Min-Seon Kim, Chung-Ju Hwang
OBJECTIVES: To identify unique characteristics of the craniofacial complex and dental maturity in girls with central precocious puberty (CPP). MATERIALS AND METHODS: This study included 34 Korean girls with idiopathic CPP (mean age, 8.6 ± .5 years) and 28 normal healthy girls of the same chronological age. An initial evaluation of the growth pattern of the craniofacial complex and dental maturity was conducted by analyzing lateral cephalometric and panoramic radiographs...
April 30, 2018: Angle Orthodontist
https://www.readbyqxmd.com/read/29706215/longitudinal-eruptive-and-posteruptive-tooth-movements-studied-on-oblique-and-lateral-cephalograms-with-implants
#14
Xiaoyun Zhang, Sheldon Baumrind, Gui Chen, Huizhong Chen, Yi Liang, Tianmin Xu
INTRODUCTION: The purpose of this study was to investigate the eruptive and posteruptive tooth displacements of untreated growing subjects longitudinally and the potential connections between posteruptive displacement of the maxillary and mandibular first molars and skeletal facial growth. METHODS: The sample comprised 11 series of right 45° oblique cephalograms and lateral cephalograms of untreated children with metallic implants of the Björk type obtained from the archives of a growth study...
May 2018: American Journal of Orthodontics and Dentofacial Orthopedics
https://www.readbyqxmd.com/read/29702010/pulp-regeneration-by-3-dimensional-dental-pulp-stem-cell-constructs
#15
Y Itoh, J I Sasaki, M Hashimoto, C Katata, M Hayashi, S Imazato
Dental pulp regeneration therapy for the pulpless tooth has attracted recent attention, and clinical trial studies are underway with the tissue engineering approach. However, there remain many concerns, including the extended period for regenerating the dental pulp. In addition, the use of scaffolds increases the risk of inflammation and infection. To establish a basic technology for novel dental pulp regenerative therapy that allows transplant of pulp-like tissue, we attempted to fabricate scaffold-free 3-dimensional (3D) cell constructs composed of dental pulp stem cells (DPSCs)...
April 1, 2018: Journal of Dental Research
https://www.readbyqxmd.com/read/29691907/investigation-of-maxillofacial-morphology-and-oral-characteristics-with-turner-syndrome-and-early-mixed-dentition
#16
Nozomi Ahiko, Yoshiyuki Baba, Michiko Tsuji, Reiko Horikawa, Keiji Moriyama
Turner syndrome (TS) is associated with an X chromosome abnormality in women and is characterized by infantilism, congenital webbed neck, and cubitus valgus. The aim of this study was to determine the maxillofacial morphology and oral characteristics of Japanese girls (mean age, 8.5 years) with TS and early mixed dentition. Lateral cephalograms obtained at the first visit were used to analyze maxillofacial morphology. Oral characteristics were identified using orthopantomograms, intraoral photographs, and study casts...
April 25, 2018: Congenital Anomalies
https://www.readbyqxmd.com/read/29687104/autotransplantation-of-teeth
#17
Puria Parvini, Karina Obreja, Georgia Trimpou, Sherin Mahmud, Robert Sader
Dental autotransplantation is the surgical transposition of a tooth from its original site to another site to replace a lost or compromised tooth in the same individual.1 It offers a method for replacing missing teeth or avulsed and traumatized teeth, particularly in children and adolescents. This surgical therapy is often overlooked as a treatment option by dentists and oral surgeons, who typically treat space closure by placing dental implants or bridges despite the fact that recent autotransplantation studies show high survival rates and success rates of 91...
2018: International Journal of Esthetic Dentistry
https://www.readbyqxmd.com/read/29682091/effectiveness-of-platelet-rich-plasma-and-bone-graft-in-the-treatment-of-intrabony-defects-a-clinico-radiographic-study
#18
Mohammad Jalaluddin, Jayachandran Mahesh, Rethi Mahesh, Ipsita Jayanti, Mohamed Faizuddin, Krishna Kripal, Nazia Nazeer
Background & Objectives: Periodontal disease is characterized by the presence of gingival inflammation, periodontal pocket formation, loss of connective tissue attachment and alveolar bone around the affected tooth. Different modalities have been employed in the treatment and regeneration of periodontal defects which include the use of bone grafts, PRP and other growth factors.The purpose of this prospective, randomized controlled study was to compare the regenerative efficacy of PRP and bonegraft in intrabony periodontal defects...
2018: Open Dentistry Journal
https://www.readbyqxmd.com/read/29671153/novel-method-for-superposing-3d-digital-models-for-monitoring-orthodontic-tooth-movement
#19
Falko Schmidt, Fatih Kilic, Neltje Emma Piro, Martin Eberhard Geiger, Bernd Georg Lapatki
Quantitative three-dimensional analysis of orthodontic tooth movement (OTM) is possible by superposition of digital jaw models made at different times during treatment. Conventional methods rely on surface alignment at palatal soft-tissue areas, which is applicable to the maxilla only. We introduce two novel numerical methods applicable to both maxilla and mandible. The OTM from the initial phase of multi-bracket appliance treatment of ten pairs of maxillary models were evaluated and compared with four conventional methods...
April 18, 2018: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/29667468/growth-hormone-receptor-gene-is-related-to-root-length-and-tooth-length-in-human-teeth
#20
Yu Hikita, Tetsutaro Yamaguchi, Daisuke Tomita, Mohamed Adel, Takatoshi Nakawaki, Koshu Katayama, Koutaro Maki, Ryosuke Kimura
OBJECTIVES: To examine the relationship between tooth length and growth hormone receptor (GHR) gene variants in a healthy Japanese population. MATERIALS AND METHODS: The subjects consisted of 193 Japanese adults (69 men, 124 women), aged 13 to 56 years. Genomic DNA was extracted from saliva and genotyped GHR rs6184 and rs6180 variants using the Taqman genotyping. Computed tomography (CT) images were acquired using a dental cone-beam CT scanner and reconstructed using open-source OsiriX medical image processing software...
April 18, 2018: Angle Orthodontist
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