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https://www.readbyqxmd.com/read/29331830/fetal-development-of-the-poeppig-s-woolly-monkey-lagothrix-poeppigii
#1
Rafael Dos Santos de Andrade, Frederico Ozanan Barros Monteiro, Hani Rocha El Bizri, Wilter Ricardo Russiano Vicente, Diva Anelie de Araujo Guimarães, Pedro Mayor
The intrauterine development is an evolutionary strategy that prepares the neonate for extra-uterine life, thus providing important information on the life history of species. In this study, we described the external and internal morphology of 25 fetuses of Poeppig's woolly monkeys (Lagothrix poeppigii) by taking advantage of a 10-year participatory collection of biological samples originated from animals hunted for subsistence purposes in the Peruvian Amazon. Logistic regressions estimated the probability of occurrence of each external morphological characteristic in relation to the crown-rump length (CRL)...
December 8, 2017: Theriogenology
https://www.readbyqxmd.com/read/29327669/advanced-3d-models-culture-to-investigate-mesenchymal-stromal-cells-of-the-human-dental-follicle
#2
Nathalie Steimberg, Francesca Angiero, Davide Farronato, Angiola Berenzi, Gianguido Cossellu, Andrea Ottonello, Darnell Kaigler, Giovanna Mazzoleni
The human dental follicle (hDF) contains the developing tooth and is involved in regulating tooth maturation and eruption. To investigate the mesenchymal stromal cells of the dental follicle, two 3D culture models were used, based on a dynamic bioreactor: the Rotary Cell Culture System (RCCS) and the 3D culture of precursor cells isolated from follicular tissue (hDFCs). The hDFCs were obtained from impacted third molars of 20 patients. Two 3D culture models were tested. In the first model, intact hDF explants were cultured in 3D conditions, preserving the original tissue architecture; they were studied via histomorphological and molecular analyses...
January 12, 2018: Tissue Engineering. Part C, Methods
https://www.readbyqxmd.com/read/29326520/the-so-called-garr%C3%A3-s-osteomyelitis-of-jaws-and-the-pivotal-utility-of-computed-tomography-scan
#3
Marco Túllio Brazão-Silva, Tiago Novaes Pinheiro
The present paper draw the attention of clinicians to investigate multiple slices of the computed tomography (CT) scan looking for a safe diagnosis of the so-called Garrè's osteomyelitis (GO) of jaws, a not uncommon disease characterized by astonishing bone growth. We report a case involving the left mandible of a 12-year-old girl presenting with a bony enlargement at left mandible. Initial examination revealed carious process of tooth 36 with radiographic apical rarefaction. However, we need to take care with this diagnosis because other aggressive diseases may cause bone enlargement mimicking GO...
October 2017: Contemporary Clinical Dentistry
https://www.readbyqxmd.com/read/29316223/probiotic-lactobacillus-sp-inhibit-growth-biofilm-formation-and-gene-expression-of-caries-inducing-streptococcus-mutans
#4
Reham Wasfi, Ola A Abd El-Rahman, Mai M Zafer, Hossam M Ashour
Streptococcus mutans contributes significantly to dental caries, which arises from homoeostasic imbalance between host and microbiota. We hypothesized that Lactobacillus sp. inhibits growth, biofilm formation and gene expression of Streptococcus mutans. Antibacterial (agar diffusion method) and antibiofilm (crystal violet assay) characteristics of probiotic Lacobacillus sp. against Streptococcus mutans (ATCC 25175) were evaluated. We investigated whether Lacobacillus casei (ATCC 393), Lactobacillus reuteri (ATCC 23272), Lactobacillus plantarum (ATCC 14917) or Lactobacillus salivarius (ATCC 11741) inhibit expression of Streptococcus mutans genes involved in biofilm formation, quorum sensing or stress survival using quantitative real-time polymerase chain reaction (qPCR)...
January 8, 2018: Journal of Cellular and Molecular Medicine
https://www.readbyqxmd.com/read/29313816/osteopontin-regulates-dentin-and-alveolar-bone-development-and-mineralization
#5
B L Foster, M Ao, C R Salmon, M B Chavez, T N Kolli, A B Tran, E Y Chu, K R Kantovitz, M Yadav, S Narisawa, J L Millán, F H Nociti, M J Somerman
The periodontal complex is essential for tooth attachment and function and includes the mineralized tissues, cementum and alveolar bone, separated by the unmineralized periodontal ligament (PDL). To gain insights into factors regulating cementum-PDL and bone-PDL borders and protecting against ectopic calcification within the PDL, we employed a proteomic approach to analyze PDL tissue from progressive ankylosis knock-out (Ank-/-) mice, featuring reduced PPi, rapid cementogenesis, and excessive acellular cementum...
December 4, 2017: Bone
https://www.readbyqxmd.com/read/29302587/conservative-management-marsupialization-of-unicystic-ameloblastoma-literature-review-and-a-case-report
#6
Jwayoung Kim, Eunkyung Nam, Sukho Yoon
Background: In this study, we present a case of unicystic ameloblastoma (UA) treated by marsupialization followed by surgical enucleation as a conservative approach. UA is a rare, benign, less aggressive, and less invasive variant of ameloblastoma that is observed quite often in younger patients. Radical approaches have effects on the physical and psychological development of a growing young patient; therefore, conservative approaches are widely used for UA management in children. Case presentation: This report described a case of an 11-year-old girl with UA of the mandibular molar-ramus area, which also involved impaction of the second and third molars...
December 2017: Maxillofacial Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29290679/heredity-genetics-and-orthodontics-how-much-has-this-research-really-helped
#7
James K Hartsfield, George Jeryn Jacob, Lorri Ann Morford
Uncovering the genetic factors that correlate with a clinical deviation of previously unknown etiology helps to diminish the unknown variation influencing the phenotype. Clinical studies, particularly those that consider the effects of an appliance or treatment regimen on growth, need to be a part of these types of genetic investigations in the future. While the day-to-day utilization of "testing" for genetic factors is not ready for practice yet, genetic testing for monogenic traits such as Primary Failure of Eruption (PFE) and Class III malocclusion is showing more promise as knowledge and technology advances...
December 2017: Seminars in Orthodontics
https://www.readbyqxmd.com/read/29284978/successful-surgical-management-of-palatogingival-groove-using-platelet-rich-fibrin-and-guided-tissue-regeneration-a-novel-approach
#8
J V Karunakaran, Susan Mathew Fenn, N Jayaprakash, N Ragavendran
Palatogingival groove also known as radicularlingual groove is a developmental anomaly involving the lingual surface of the maxillary incisors. They are inconspicuous, funnel-shaped, extend for varying distances on root surface and occur due to infolding of the hertwigs epithelial root sheath. This encourages adherence of microorganisms and plaque to levels significant for pathological changes resulting in endodontic and periodontal lesions. The variations in anatomy of the tooth as a cause of pulp necrosis in teeth of anterior maxillary segment should be considered by the clinician when other etiological factors are ruled out...
November 2017: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/29282871/minimally-invasive-esthetic-ridge-preservation-with-growth-factor-enhanced-bone-matrix
#9
Marc L Nevins, Sherif Said
OBJECTIVES: Extraction socket preservation procedures are critical to successful esthetic implant therapy. Conventional surgical approaches are technique sensitive and often result in alteration of the soft tissue architecture, which then requires additional corrective surgical procedures. This case series report presents the ability of flapless surgical techniques combined with a growth factor-enhanced bone matrix to provide esthetic ridge preservation at the time of extraction for compromised sockets...
December 28, 2017: Journal of Esthetic and Restorative Dentistry
https://www.readbyqxmd.com/read/29250467/incremental-growth-of-therizinosaurian-dental-tissues-implications-for-dietary-transitions-in-theropoda
#10
Khai Button, Hailu You, James I Kirkland, Lindsay Zanno
Previous investigations document functional and phylogenetic signals in the histology of dinosaur teeth. In particular, incremental lines in dentin have been used to determine tooth growth and replacement rates in several dinosaurian clades. However, to date, few studies have investigated the dental microstructure of theropods in the omnivory/herbivory spectrum. Here we examine dental histology of Therizinosauria, a clade of large-bodied theropods bearing significant morphological evidence for herbivory, by examining the teeth of the early-diverging therizinosaurian Falcarius utahensis, and an isolated tooth referred to Suzhousaurus megatherioides, a highly specialized large-bodied representative...
2017: PeerJ
https://www.readbyqxmd.com/read/29249735/longitudinal-observation-of-maxillary-sinus-bony-bridges-and-septa-in-childhood
#11
Munetaka Naitoh, Hirofumi Watanabe, Kazuhito Yoshida, Hisashi Hayashi, Kenichi Gotoh, Eiichiro Ariji
The rate of septum presence in the maxillary sinus has been reported to be over 30%. It was considered that a bony bridge might change to a maxillary sinus septum with growth in a previous study using dry child skulls. In the present investigation, maxillary sinus bony bridges and septa were longitudinally observed using computed tomography (CT). Multislice CT was performed in three patients. A bony bridge was defined as a bony structure between the maxillary sinus wall and dental germ. Also, a septum was defined as a pointed bony structure in the inferior wall of the maxillary sinus...
2017: Okajimas Folia Anatomica Japonica
https://www.readbyqxmd.com/read/29248886/impact-of-birth-characteristics-breast-feeding-and-vital-statistics-on-the-eruption-of-primary-teeth-among-healthy-infants-in-saudi-arabia-an-observational-study
#12
Kholoud Abdullah Alnemer, Sharat Chandra Pani, Alaa M Althubaiti, Manal Bawazeer
OBJECTIVES: This study aimed to explore the impact of gender, birth weight, maternal age, type of delivery, gestational age and feeding practices on the eruption of teeth in children with no underlying medical conditions or developmental defects in their first year of life. DESIGN: A cross-sectional observational study design was used. SETTING: A primary healthcare setting in Riyadh, Saudi Arabia. PARTICIPANTS: All children in their first year of life attending a vaccination clinic (n=422) were included in the study...
December 15, 2017: BMJ Open
https://www.readbyqxmd.com/read/29246495/elevated-peripheral-myelin-protein-22-reduced-mitotic-potential-and-proteasome-impairment-in-dermal-fibroblasts-from-charcot-marie-tooth-disease-type-1a-patients
#13
Sooyeon Lee, Hannah Bazick, Vinita Chittoor-Vinod, Mohammed Omar Al Salihi, Guangbin Xia, Lucia Notterpek
A common form of hereditary autosomal dominant demyelinating neuropathy known as Charcot-Marie-Tooth disease type 1A (CMT1A) is linked with duplication of the peripheral myelin protein 22 (PMP22) gene. Although studies from animal models have led to better understanding of the pathobiology of these neuropathies, there continues to be a gap in the translation of findings from rodents to humans. As PMP22 was originally identified in fibroblasts as growth arrest specific gene 3 (gas3) and is expressed broadly in the body, it was tested whether skin cells from neuropathic patients would display the cellular pathology observed in Schwann cells from rodent models...
December 12, 2017: American Journal of Pathology
https://www.readbyqxmd.com/read/29243816/two-decades-of-persisting-income-disparities-in-dental-caries-among-u-s-children-and-adolescents
#14
Gary Douglas Slade, Anne Elizabeth Sanders
OBJECTIVE: To describe trends in income disparities in dental caries among U.S. children and adolescents during two decades of fluctuating economic growth. METHODS: Data were from National Health and Nutrition Examination Surveys conducted in 1988-1994, 1999-2004, and 2011-2014. The number of tooth surfaces with dental caries experience per child was computed for three age groups: 2-5, 6-11, and 12-17 years. Absolute and relative measures of inequality compared caries experience in families below the poverty level with families where income was at least three times the poverty threshold...
December 15, 2017: Journal of Public Health Dentistry
https://www.readbyqxmd.com/read/29241366/accuracy-of-dental-development-for-estimating-the-pubertal-growth-spurt-in-comparison-to-skeletal-development-a-systematic-review-and-meta-analysis
#15
Marcos Av Bittencourt, Graziela O Cericato, Ademir Franco, Rafaela S Girão, Anderson Pb Lima, Luiz R Paranhos
OBJECTIVES: This study aimed to search for scientific evidence concerning the accuracy of dental development for estimating the pubertal growth spurt. METHODS: It was conducted according to the statements of PRISMA. An electronic search was performed in six databases, including the grey literature. The PICOS strategy was used to define the eligibility criteria and only observational studies were selected. RESULTS: Out of 1,416 identified citations, ten papers fulfilled the criteria and were included in this systematic review...
December 15, 2017: Dento Maxillo Facial Radiology
https://www.readbyqxmd.com/read/29240953/influence-of-excess-branched-chain-amino-acid-uptake-by-streptococcus-mutans-in-human-host-cells
#16
Takafumi Arimoto, Rei Yambe, Hirobumi Morisaki, Haruka Umezawa, Hideo Kataoka, Shohei Matsui, Hirotaka Kuwata
Oral streptococci, including cariogenic bacterium Streptococcus mutans, comprise a large percentage of human supragingival plaque, which contacts both tooth surfaces and gingiva. Eukaryotic cells are able to take up macromolecules and particles, including bacteria, by endocytosis. Increasing evidence indicates endocytosis may be used as an entry process by bacteria. We hypothesized some endocytosed bacteria might survive and obtain nutrients, such as amino acids, until they are killed. To verify this hypothesis, we focused on bacterial utilization of branched-chain amino acids (BCAAs; isoleucine, leucine, and valine) in host cells...
December 12, 2017: FEMS Microbiology Letters
https://www.readbyqxmd.com/read/29238373/guided-tissue-regeneration-and-platelet-rich-growth-factor-for-the-treatment-of-grade-ii-furcation-defects-a-randomized-double-blinded-clinical-trial-a-pilot-study
#17
Niloofar Jenabian, Sina Haghanifar, Hodis Ehsani, Ehsan Zahedi, Masumeh Haghpanah
Background: The treatment of furcation area defects remained as a challenging issue in periodontal treatments. Regeneration treatment of furcation defects is the most discussed periodontal treatment. Although not completely hopeless in prognosis, the presence of the furcation involvement significantly increases the chance of tooth loss. The current research was conductedeto compare theeadditive effect of combined guided tissue regeneration (GTR) and platelet-rich growth factor (PRGF) on the treatment of furcation bony defects...
November 2017: Dental Research Journal
https://www.readbyqxmd.com/read/29235378/the-hexane-fraction-of-bursera-microphylla-a-gray-induces-p21-mediated-anti-proliferative-and-pro-apoptotic-effects-in-human-cancer-derived-cell-lines
#18
Sabrina Adorisio, Alessandra Fierabracci, Giulia Gigliarelli, Isabella Muscari, Lorenza Cannarile, Anna Marina Liberati, Maria Carla Marcotullio, Carlo Riccardi, Massimo Curini, Ramon Enrique Robles Zepeda, Domenico V Delfino
Bursera microphylla (BM), one of the common elephant trees, is widely distributed in the Sonoran Desert in Mexico. The Seri ethnic group in the Sonoran Desert uses BM as an anti-inflammatory and painkiller drug for the treatment of sore throat, herpes labialis, abscessed tooth, and wound healing. Dried stems and leaves of BM are used in a tea to relieve painful urination and to stimulate bronchial secretion. Furthermore, BM is used for fighting venereal diseases. To investigate the effects of the hexane fraction of resin methanol extract (BM-H) on cell growth, the acute myeloid cell line (OCI-AML3) was treated with 250, 25, or 2...
March 1, 2017: Integrative Cancer Therapies
https://www.readbyqxmd.com/read/29229147/effects-of-dermal-wounding-on-distal-primary-tumor-immunobiology-in-mice
#19
Leah M Pyter, Daniel B McKim, Yasmin Husain, Humberto Calero, Jonathan P Godbout, John F Sheridan, Phillip T Marucha, Christopher G Engeland
BACKGROUND: Before primary oral tumors are treated, various prophylactic procedures that require tissue repair are often necessary (e.g. biopsies, tooth extractions, radiation, and tracheotomies). Wound healing and tumor growth harness similar immune/inflammatory mechanisms. Our previous work indicates that tumors impair wound healing, although the extent to which tissue repair conversely influences tumor growth is poorly understood. Here, we test the hypothesis that dermal wound healing exacerbates primary tumor growth and influences tumor immunobiology...
January 2018: Journal of Surgical Research
https://www.readbyqxmd.com/read/29223639/extensive-phenotyping-of-the-orofacial-and-dental-complex-in-crouzon-syndrome
#20
Alexander Khominsky, Robin Yong, Sarbin Ranjitkar, Grant Townsend, Peter J Anderson
OBJECTIVES: Fibroblast growth factor receptor 2 (FGFR2) C342Y/+ mutation is a known cause of Crouzon syndrome that is characterised by craniosynostosis and midfacial hypoplasia. Our aim was to conduct extensive phenotyping of the maxillary, mandibular and dental morphology associated with this mutation. MATERIALS AND METHODS: Morphometric data were obtained from 40 mice, representing two genotypes (Crouzon and wild-type) and two sexes (males and females) (n=10 in each group)...
October 27, 2017: Archives of Oral Biology
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