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https://www.readbyqxmd.com/read/29141490/study-on-enhanced-lymphatic-tracing-of-isosulfan-blue-injection-by-influence-of-osmotic-pressure-on-lymphatic-exposure
#1
Tiantian Ye, Rui He, Yue Wu, Lei Shang, Shujun Wang
Isosulfan blue (IB) is being used as a lymphatic tracer has been approved by the FDA in 1981. This study aimed at improving lymphatic exposure of IB injection by osmotic pressure regulation to achieve step-by step lymphatic tracing. First, IB injection with appropriate osmotic pressure, stability and suitable pH was prepared. Next, the lymphatic tracing ability of different osmotic pressure was studied to determine the blue-stained state of IB in three-level lymph nodes after subcutaneous administration. Furthermore, pharmacokinetics of lymphatic drainage, lymph node uptake and plasma concentration was investigate to explore the improving law of the lymphatic tracing by osmotic pressure, and combined with tissue irritation to determine the optimal osmotic pressure...
November 15, 2017: Drug Development and Industrial Pharmacy
https://www.readbyqxmd.com/read/29132521/gallbladder-dysfunction-cholecystitis-choledocholithiasis-cholangitis-and-biliary-dyskinesia
#2
REVIEW
Thad Wilkins, Edward Agabin, Jason Varghese, Asif Talukder
The prevalence of gallstones is 10% to 15% in adults. Individuals with acute cholecystitis present with right upper quadrant pain, fever, and leukocytosis. Management includes supportive care and cholecystectomy. The prevalence of choledocholithiasis is 10% to 20%, and serious complications include cholangitis and gallstone pancreatitis. The goal of management in individuals with choledocholithiasis consists of clearing common bile duct stones. Acute ascending cholangitis is a life-threatening condition involving acute inflammation and infection of the common bile duct...
December 2017: Primary Care
https://www.readbyqxmd.com/read/29131247/comparison-of-cholecystectomy-and-percutaneous-cholecystostomy-in-acute-cholecystitis-results-of-a-retrospective-study
#3
A La Greca, M Di Grezia, S Magalini, A Di Giorgio, C Lodoli, G Di Flumeri, V Cozza, G Pepe, M Foco, M Bossola, D Gui
OBJECTIVE: To retrospectively compare the clinical outcomes of percutaneous cholecystostomy (PC) and cholecystectomy in patients with acute cholecystitis admitted to an urban University Hospital. PATIENTS AND METHODS: We studied 646 patients with acute cholecystitis. Ninety patients had placement of a PC at their index hospitalization, and 556 underwent cholecystectomy. Of the 90 patients with PC, 13 underwent subsequent elective cholecystectomy. RESULTS: Overall, in-hospital mortality and postoperative complications were significantly higher in patients who received PC than in those who underwent cholecystectomy...
October 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29124380/chemoembolisation-for-hepatocellular-carcinoma-with-bile-duct-invasion-is-preprocedural-biliary-drainage-mandatory
#4
Juil Park, Hyo-Cheol Kim, Jeong-Hoon Lee, EunJu Cho, Minuk Kim, Saebeom Hur, Hwan Jun Jae, Myungsu Lee, Jin Wook Chung
PURPOSE: To determine the necessity of preprocedural biliary drainage prior to chemoembolisation for hepatocellular carcinoma (HCC) with bile duct invasion. MATERIALS AND METHODS: The study included 52 patients who received chemoembolisation for unresectable HCC invading bile duct and causing hyperbilirubinemia (>3 mg/dL). Patients were divided into three groups according to biliary drainage and its effect: effective drainage (n=21), ineffective drainage (n=17), and non-drainage (n=14)...
November 9, 2017: European Radiology
https://www.readbyqxmd.com/read/29124119/endoscopic-ultrasound-guided-gallbladder-drainage-for-acute-cholecystitis-with-a-silicone-covered-nitinol-short-bilaterally-flared-stent-a-case-series
#5
Raffaele Manta, Claudio Zulli, Angelo Zullo, Edoardo Forti, Alberto Tringali, Lorenzo Dioscoridi, Francesco Zito, Helga Bertani, Rita Conigliaro, Massimiliano Mutignani
Background and study aim: Gallbladder drainage in patients with cholecystitis who are unsuitable for surgery may be performed by endoscopic ultrasound (EUS)-guided placement of specifically designed fully covered metal stents. We describe the first case series of patients treated with a silicone-covered nitinol stent with bilateral anchor flanges. Patients and methods: Data from consecutive patients with acute cholecystitis who were deemed unsuitable candidates for surgery were collected...
November 2017: Endoscopy International Open
https://www.readbyqxmd.com/read/29123581/surgical-treatment-of-hepatic-echinococcus-granulosus
#6
Waldemar Patkowski, Maciej Krasnodębski, Michał Grąt, Łukasz Masior, Marek Krawczyk
Introduction: Infections caused by metacestode stage of the Echinococcus granulosus in humans result in disease named cystic echinococcosis. Aim: To present the outcomes of patients treated surgically for cystic echinococcosis of the liver. Material and methods: One hundred and nineteen patients treated in the period between 1989 and 2014 due to E. granulosus infection in the Department of General, Transplant, and Liver Surgery, Medical University of Warsaw were selected for this retrospective study...
2017: Przegla̜d Gastroenterologiczny
https://www.readbyqxmd.com/read/29118686/hepatectomy-for-hilar-cholangiocarcinoma-with-right-sided-ligamentum-teres-using-a-hepatectomy-simulation-system
#7
Seikan Hai, Etsuro Hatano, Tadamichi Hirano, Yasukane Asano, Kazuhiro Suzumura, Hideaki Sueoka, Jiro Fujimoto
Right-sided ligamentum teres (RSLT) is a rare congenital anomaly often accompanied by variation of the hepatic vasculature. We herein report a surgical case of a hilar cholangiocarcinoma with RSLT in whom preoperative hepatectomy simulation proved useful for understanding the anatomical structure of the liver. A 78-year-old male with obstructive jaundice was referred to our department for further examination. The patient was suspected of having a hilar cholangiocarcinoma originating from the left hepatic bile duct by contrast-enhanced computed tomography (CT), and CT also showed right umbilical portion (RUP)...
September 2017: Case Reports in Gastroenterology
https://www.readbyqxmd.com/read/29116342/gastroenterology-and-pancreatic-adenocarcinoma-what-the-radiologist-needs-to-know
#8
Abhik Bhattacharya, Namita S Gandhi, Mark E Baker, Prabhleen Chahal
In this article, we review the information that radiologists need to know regarding the endoscopic approach to the diagnosis and management of pancreatic cancer. This includes a review of the indications, techniques, and complications of endoscopic ultrasound. We also review information regarding endoscopic retrograde cholangiopancreatography, including the various biliary drainage techniques and the use of endoscopic palliation for patients with pancreatic cancer.
November 7, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/29112915/acute-abdomen-secondary-to-a-spontaneous-perforation-of-the-biliary-tract-a-rare-complication-of-choledocholithiasis
#9
G A Gómez-Torres, F M Rodríguez-Navarro, C R López-Lizárraga, C A Bautista-López, O S Ortega-García, G Becerra-Navarro, A Águila-Barragán, C F Ploneda-Valencia
INTRODUCTION: The spontaneous perforation of the biliary tract (SPBT) is an extremely rare cause of peritonitis, which was first described by Freeland in 1982, to date only around 70 cases have been reported. Here we present a case of spontaneous perforation of the biliary tract, in a patient with choledocholithiasis, which was treated with ultrasound-guided drainage and ERCP. CASE REPORT: A 51-year-old male was admitted to the emergency room for 15-day evolution jaundice, localized pain in the right flank and hypochondrium of 3days...
October 27, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29108980/radiofrequency-ablation-combined-with-biliary-stent-placement-versus-stent-placement-alone-for-malignant-biliary-strictures-a-systematic-review-and-meta-analysis
#10
REVIEW
Aijaz Ahmed Sofi, Muhammad Ali Khan, Ananya Das, Mankanwal Sachdev, Sadik Khuder, Ali Nawras, Wade Lee
Unresectable malignant biliary strictures are generally managed by palliative stent placement for drainage of biliary tree. Recently, radiofrequency ablation (RFA) has been used to improve the patency of biliary stents in these patients. Several studies have evaluated the effectiveness of biliary stent placement with RFA on stent patency and patient survival with variable results. We performed this meta-analysis to evaluate the efficacy and safety of biliary stent placement with RFA compared with stent placement alone in patients with malignant biliary strictures...
November 3, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29108354/ultrasound-guided-percutaneous-microwave-ablation-assisted-by-three-dimensional-visualization-operative-treatment-planning-system-and-percutaneous-transhepatic-cholangial-drainage-with-intraductal-chilled-saline-perfusion-for-larger-hepatic-hilum-hepatocellular
#11
Xin Li, Jie Yu, Ping Liang, Xiaoling Yu, Zhigang Cheng, Zhiyu Han, Shaobo Duan, Jiasheng Zheng
To assess the clinical efficiency of ultrasound-guided percutaneous microwave ablation (US-PMWA) assisted by three-dimensional (3D) visualization operative treatment planning system and percutaneous transhepatic cholangial drainage with intraductal chilled saline perfusion (PTCD-ICSP) for larger hepatic hilum hepatocellular carcinoma (HH-HCC) (D ≥ 3 cm). The combination therapy was performed in 14 patients from Sep 2011 to May 2017. The major outcomes for assessment were biliary duct complications, local tumor recurrence, distant recurrence and overall survival rates...
October 3, 2017: Oncotarget
https://www.readbyqxmd.com/read/29105846/the-role-of-two-step-eus-guided-antegrade-treatment-as-an-option-for-bile-duct-stones-in-patients-with-surgically-altered-anatomy
#12
EDITORIAL
Masaaki Shimatani, Toshiyuki Mitsuyama, Makoto Takaoka, Kazuichi Okazaki
The treatment of bile duct stones in patients with surgically altered anatomy had been difficult for management until the balloon assisted endoscope (BAE) approach was introduced. Patients had been referred to either percutaneous transhepatic biliary drainage (PTBD) or surgical operation which were the gold standard, though they were invasive and indication was limited. For example, percutaneous drainage is relatively contraindicated in patients with significant ascites, obesity, and/or non-dilated bile duct...
November 6, 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/29102756/feasibility-and-safety-of-percutaneous-transhepatic-endobiliary-radiofrequency-ablation-as-an-adjunct-to-biliary-stenting-in-malignant-biliary-obstruction
#13
B Acu, E Kurtulus Ozturk
PURPOSE: The purpose of this study was to investigate the feasibility and safety of percutaneous transhepatic endobiliary radiofrequency ablation (RFA) combined with biliary stenting in palliative treatment of malignant biliary obstructions. MATERIALS AND METHODS: Twenty-one patients who had undergone percutaneous transhepatic endobiliary RFA as an adjunct to biliary stenting were included. There were 12 men and nine women with a mean age of 67±13.6 (SD) years (range: 34-86 years)...
November 1, 2017: Diagnostic and Interventional Imaging
https://www.readbyqxmd.com/read/29097861/biliary-complications-after-hepatic-trauma-in-children
#14
Riccardo Guanà, Carbonaro Giulia, Andrea Brunati, Salvatore Garofalo, Jurgen Schleef
Aim of the Study: In pediatric patients with liver trauma and hemodynamic stability, conservative treatment is acknowledged as the gold standard. Patients and Methods: We conducted a retrospective analysis of 116 consecutive pediatric patients (<14-year-old) observed at our institution for closed abdominal trauma from January 2010 to January 2016. Among these, 16 patients (13%) had hepatic trauma Grade II or more, according to Moore liver trauma injury score...
October 2017: Journal of Emergencies, Trauma, and Shock
https://www.readbyqxmd.com/read/29097348/percutaneous-transhepatic-techniques-for-retrieving-fractured-and-intrahepatically-dislodged-percutaneous-transhepatic-biliary-drainage-catheters
#15
Liu Hsien-Tzu, Tseng Hsiuo Shan, Chiu Nai Chi, Lin Yi Yang, Chiou Yi You, Liu Chien An
Dislodged intrabiliary drainage devices, including catheters, endoprostheses, and stents, may further impair drainage and cause various local reactions, vascular and gastrointestinal tract complications. Endoscopic approaches for management of plastic biliary endoprostheses have been extensively discussed. However, in rare cases of fracture of percutaneous transhepatic biliary drainage (PTBD) catheters, only a percutaneous transhepatic technique for retrieving should be applied to avoid further damage by its rigid fragment...
November 2017: Diagnostic and Interventional Radiology: Official Journal of the Turkish Society of Radiology
https://www.readbyqxmd.com/read/29095941/role-of-endoscopic-biliary-drainage-in-advanced-hepatocellular-carcinoma-with-jaundice
#16
Hyun Young Woo, Sung Yong Han, Jeong Heo, Dong Uk Kim, Dong Hoon Baek, So Yong Yoo, Chang Won Kim, Suk Kim, Geun Am Song, Mong Cho, Dae Hwan Kang
BACKGROUND: Patients with advanced hepatocellular carcinoma (HCC) with jaundice have an extremely poor prognosis. Although biliary drainage can resolve obstructive jaundice, signs of obstruction may not be evident. This study evaluated the role of endoscopic biliary drainage in patients with advanced HCC and obstructive jaundice. METHODS: From 2010 to 2015, 74 patients underwent endoscopic biliary drainage for obstructive jaundice due to advanced HCC. Jaundice resolution was defined as complete response and total bilirubin concentration below 3 mg/dl...
2017: PloS One
https://www.readbyqxmd.com/read/29095426/eus-guided-choledochoduodenostomy-versus-hepaticogastrostomy-a-systematic-review-and-meta-analysis
#17
Ricardo S Uemura, Muhammad Ali Khan, José P Otoch, Michel Kahaleh, Edna F Montero, Everson L A Artifon
BACKGROUND AND AIMS: Endoscopic ultrasound-guided biliary drainage (EUS-BD) has emerged as an alternative in cases of endoscopic retrograde cholangiopancreatography (ERCP) failure. Two types of EUS-BD methods for achieving biliary drainage when ERCP fails are choledochoduodenostomy (CDS) or hepaticogastrostomy (HGS). However, there is no consensus if one approach is better than the other. Therefore, we conducted a systematic review and meta-analysis to evaluate these 2 main EUS-BD methods...
October 31, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/29093418/percutaneous-transhepatic-self-expanding-metallic-stent-placement-for-the-treatment-of-malignant-afferent-loop-obstruction
#18
Naruomi Jinno, Itaru Naitoh, Yoshihito Nagura, Kazutoshi Fujioka, Yusuke Mizuno, Junko Momose, Makoto Ooyama, Kazuki Hayashi, Tomokatsu Miyaki, Makoto Nakamura, Takashi Joh
We report the case of a 71-year-old man with afferent loop obstruction (ALO) after Roux-en-Y reconstruction due to gastric cancer. Computed tomography showed a distended afferent loop and a dilatated bile duct. We could not reach the stricture site in the afferent loop using a gastroscope. We performed percutaneous transhepatic biliary drainage (PTBD) and placed a self-expanding metallic stent (SEMS) in the duodenal stricture through the PTBD route. Although an endoscopic approach is preferable, when PTBD can be performed, percutaneous transhepatic SEMS placement might be an alternative option for treating ALO in cases in which it is not possible to reach the site of stenosis with an endoscope...
November 1, 2017: Internal Medicine
https://www.readbyqxmd.com/read/29080097/hydromorphone-hydrochloride-use-during-various-interventional-radiology-procedures-pain-control-and-adverse-events-a-case-series-audit-analysis
#19
Thea Moran, Amit Prabhakar, James H Diaz, Alan David Kaye
INTRODUCTION: This project studied pain control and the development of adverse events before, during, and after the administration of hydromorphone hydrochloride for various interventional radiology (IR) procedures. METHODS: We performed a retrospective analysis of 100 patients (men = 58; women = 42) sedated with peri-procedural intravenous (IV) hydromorphone in association with various IR procedures. We stratified the procedures as follows: abscess drainages (M = 8; F = 8), arteriograms (M = 1; F = 0), biliary interventions (M = 3; F = 2), bone biopsies (M = 2; F = 2), non-bone biopsies (M = 26; F = 19), non-tunneled venous catheters (M = 1; F = 1), tunneled venous catheters (M = 7; F = 5), embolization (M = 4; F = 0), IVC filter placement (M = 1; F = 1), nephrostomy tube placement (M = 1; F = 4), and percutaneous nephrolithotomy tube placements (M = 4; F = 0)...
October 27, 2017: Pain and Therapy
https://www.readbyqxmd.com/read/29070759/total-bilirubin-amount-in-drainage-fluid-can-be-an-early-predictor-for-severe-biliary-fistula-after-hepatobiliary-surgery
#20
Toshitaka Sugawara, Junichi Shindoh, Yujiro Nishioka, Masaji Hashimoto
The ratio of the bilirubin concentration in abdominal drainage fluid to the serum bilirubin concentration (d-Bil/s-Bil) has been used as a predictor of biliary fistula (BF) formation after hepatobiliary surgery. The d-Bil/s-Bil ratio is highly influenced by the amount of drainage and is not always reliable, especially when the amount of drainage is large. In this study, the usefulness of the d-Bil/s-Bil ratio and total bilirubin amount in the drainage fluid (TBA) (bilirubin concentration in the drainage fluid x the amount of drainage) as predictors of severe BF (sBF) formation was evaluated retrospectively from the data of 306 patients who had undergone hepatobiliary surgery...
October 24, 2017: Bioscience Trends
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