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https://www.readbyqxmd.com/read/28720199/a-national-survey-exploring-uk-trainees-perceptions-core-training-experience-and-decisions-to-pursue-advanced-training-in-breast-radiology
#1
S Lowes, M Bydder, R Sinnatamby
AIM: To investigate UK radiology trainees' perceptions of breast radiology and the factors that influenced their decision whether or not to choose breast radiology as an area of special interest. MATERIALS & METHODS: An online survey was compiled and distributed to all UK specialty trainees in clinical radiology via the Royal College of Radiologists Junior Radiologists' Forum (JRF) regional representatives. RESULTS: There were 275 respondents, representing 22% of all UK radiology trainees...
July 15, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/28717726/breast-cancer-reporting-in-lagos-nigeria-implications-for-training-and-education-in-africa
#2
Adetola O Daramola, Adekunbiola A Banjo, Aneliese Bennett, Fatimah Abdulkareem, Abeer M Shaaban
PURPOSE: To assess the completeness and accuracy of breast cancer pathologic reporting in Nigeria. MATERIALS AND METHODS: The histologic parameters provided in breast cancer pathology reports at a large teaching hospital in Nigeria were assessed. The corresponding slides were reviewed after the United Kingdom Royal College of Pathologists guidelines, and results were compared. RESULTS: Out of 115 breast cancer cases, histologic type of breast carcinoma was concordant with the review type in 53...
December 2016: Journal of Global Oncology
https://www.readbyqxmd.com/read/28713586/formal-thought-disorder-in-people-at-ultra-high-risk-of-psychosis
#3
Arsime Demjaha, Sara Weinstein, Daniel Stahl, Fern Day, Lucia Valmaggia, Grazia Rutigliano, Andrea De Micheli, Paolo Fusar-Poli, Philip McGuire
BACKGROUND: Formal thought disorder is a cardinal feature of psychosis. However, the extent to which formal thought disorder is evident in ultra-high-risk individuals and whether it is linked to the progression to psychosis remains unclear. AIMS: Examine the severity of formal thought disorder in ultra-high-risk participants and its association with future psychosis. METHOD: The Thought and Language Index (TLI) was used to assess 24 ultra-high-risk participants, 16 people with first-episode psychosis and 13 healthy controls...
July 2017: BJPsych Open
https://www.readbyqxmd.com/read/28713585/associations-of-centrally-acting-ace-inhibitors-with-cognitive-decline-and-survival-in-alzheimer-s-disease
#4
Karim Fazal, Gayan Perera, Mizanur Khondoker, Robert Howard, Robert Stewart
BACKGROUND: Cognitive improvement has been reported in patients receiving centrally acting angiotensin-converting enzyme inhibitors (C-ACEIs). AIMS: To compare cognitive decline and survival after diagnosis of Alzheimer's disease between people receiving C-ACEIs, non-centrally acting angiotensin-converting enzyme inhibitors (NC-ACEIs), and neither. METHOD: Routine Mini-Mental State Examination (MMSE) scores were extracted in 5260 patients receiving acetylcholinesterase inhibitors and analysed against C-/NC-ACEI exposure at the time of Alzheimer's disease diagnosis...
July 2017: BJPsych Open
https://www.readbyqxmd.com/read/28708807/a-systematic-review-of-internet-decision-making-resources-for-patients-considering-surgery-for-ulcerative-colitis
#5
Daniel M Baker, Jack H Marshall, Matthew J Lee, Georgina L Jones, Steven R Brown, Alan J Lobo
BACKGROUND: Guidance from the Royal College of Surgeons advocates patient use of on-line resources to assist in decision making. Our aim was to assess the quality of on-line resources to facilitate decision making for patients considering surgery for ulcerative colitis (UC). METHODS: We undertook a systematic review based on PRISMA guidelines. This was registered on the PROSPERO database (CRD42016047177). We searched Google and repositories using several lay search terms for patient information discussing surgery for UC, published in English...
August 2017: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/28707313/predictive-factors-for-publication-of-abstracts-at-the-royal-australasian-college-of-surgeons-annual-scientific-congress
#6
Cristian Udovicich, Bryan Soh, Sam Law, Venetia Hoe, Dion Lanfranco, Kalpa Perera, Cuong Duong, Steven Chan
BACKGROUND: A key metric of the research quality of medical conferences is the publication rate of abstracts. The study objective was to determine the publication rate of abstracts presented at the Royal Australasian College of Surgeons Annual Scientific Congress (RACS ASC) and to examine for any predictive factors associated with publication. METHODS: Abstracts presented at the RACS ASC from 2011 to 2013 were analysed. Abstract characteristics such as presentation format, study type, study design, study site, cohort size and author origin were recorded...
July 13, 2017: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/28700433/data-set-for-the-reporting-of-carcinomas-of-the-cervix-recommendations-from-the-international-collaboration-on-cancer-reporting-iccr
#7
W Glenn McCluggage, Meagan J Judge, Isabel Alvarado-Cabrero, Máire A Duggan, Lars-Christian Horn, Pei Hui, Jaume Ordi, Christopher N Otis, Kay J Park, Marie Plante, Colin J R Stewart, Edwin K Wiredu, Brian Rous, Lynn Hirschowitz
A comprehensive pathologic report is essential for optimal patient management, cancer staging and prognostication. In many countries, proforma reports are used but the content of these is variable. The International Collaboration on Cancer Reporting is an alliance formed by the Royal Colleges of Pathologists of Australasia and the United Kingdom, the College of American Pathologists, the Canadian Partnership Against Cancer and the European Society of Pathology, for the purpose of developing standardized, evidence-based reporting data sets for each cancer site...
July 11, 2017: International Journal of Gynecological Pathology
https://www.readbyqxmd.com/read/28699463/investigating-the-attitudes-of-nurses-who-are-obese
#8
Jane Wills, Muireann Kelly
The prevalence of obesity is higher among nurses than in any other group of healthcare professionals. Obesity is an issue for the nursing workforce because of its effects on work-related sickness absence and productivity, through related conditions such as arthritis and diabetes. Aim To investigate the attitudes, motivations and behaviours of, and the uptake of workplace health initiatives by, nurses who are obese. Method Nurses who are or were obese and who practised in England were recruited at the Royal College of Nursing congress in Glasgow in June 2016...
July 12, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28698719/long-term-safety-of-transplanting-human-bone-marrow-stromal-cells-into-the-extravascular-spaces-of-the-choroid-of-rabbits
#9
Adi Tzameret, Sapir E Kalish, Ifat Sher, Lea Twito, Amilia Meir, Itay Levy, Shlomo Margel, Iris Moroz, Mordechai Rosner, Avraham J Treves, Arnon Nagler, Michael Belkin, Ygal Rotenstreich
Incurable neuroretinal degeneration diseases cause severe vision loss and blindness in millions of patients worldwide. In previous studies, we demonstrated that transplanting human bone marrow stromal cells (hBMSCs) in the extravascular spaces of the choroid (EVSC) of the Royal College of Surgeon rats ameliorated retinal degeneration for up to 5 months. Assessing the safety of hBMSC treatment and graft survival in a large animal is a crucial step before initiating clinical trials. Here, we transplanted hBMSCs into the EVSC compartment of New Zealand White rabbits...
2017: Stem Cells International
https://www.readbyqxmd.com/read/28697493/does-the-margin-matter-in-esophageal-cancer
#10
Karl-Frederick Karstens, Jakob R Izbicki, Matthias Reeh
BACKGROUND: The prognostic impact of circumferential resection margin (CRM) involvement in resected esophageal cancer (EC) is controversial discussed. The College of American Pathologists (CAP) and the Royal College of Pathologists (RCP) provide 2 different definitions of CRM involvement. The aim of this systematic review was to evaluate the clinical significance of CRM involvement on patients' survival following esophagectomy due to EC. METHODS: PubMed, Science Direct, and Google scholar were searched for studies analyzing the clinical impact of CRM in EC...
July 12, 2017: Digestive Surgery
https://www.readbyqxmd.com/read/28696434/when-should-governments-increase-the-supply-of-psychiatric-beds
#11
S Allison, T Bastiampillai, J Licinio, D A Fuller, N Bidargaddi, S S Sharfstein
Low numbers of hospital-based psychiatric beds create problems for people with severe mental illness (SMI), when they face extended emergency department (ED) waits, higher thresholds for admission to an acute bed, and short revolving-door stays with high rates of rehospitalisation. Limited access to inpatient treatment has been associated with higher suicide risk, premature mortality, homelessness, violent crime and incarceration. Ultimately, people with SMI can be transinstitutionalised to the criminal justice system...
July 11, 2017: Molecular Psychiatry
https://www.readbyqxmd.com/read/28694340/colonisation-of-irish-patients-with-chronic-obstructive-pulmonary-disease-by-streptococcus-pneumoniae-and-analysis-of-the-pneumococcal-vaccine-coverage-a-non-interventional-observational-prospective-cohort-study
#12
Hannah McCarthy, Mandy Jackson, Mary Corcoran, Martha McElligott, Elaine MacHale, Imran Sulaiman, Breda Cushen, Richard W Costello, Hilary Humpreys
OBJECTIVES: To characterise the pattern of colonisation and serotypes of Streptococcus pneumoniae among patients with chronic obstructive pulmonary disease (COPD) who currently receive the 23-valent pneumococcal polysaccharide vaccine (PPV-23) according to vaccination status, use of antibiotics and steroids. To investigate the prevalence of PPV-23 and 13-valent pneumococcal conjugate vaccine (PCV-13) serotypes within the study cohort. DESIGN: A non-interventional, observational, prospective cohort study with a 12 -month follow-up period inclusive of quarterly study visits...
July 9, 2017: BMJ Open
https://www.readbyqxmd.com/read/28694034/insertion-and-deletion-derived-tumour-specific-neoantigens-and-the-immunogenic-phenotype-a-pan-cancer-analysis
#13
Samra Turajlic, Kevin Litchfield, Hang Xu, Rachel Rosenthal, Nicholas McGranahan, James L Reading, Yien Ning S Wong, Andrew Rowan, Nnennaya Kanu, Maise Al Bakir, Tim Chambers, Roberto Salgado, Peter Savas, Sherene Loi, Nicolai J Birkbak, Laurent Sansregret, Martin Gore, James Larkin, Sergio A Quezada, Charles Swanton
BACKGROUND: The focus of tumour-specific antigen analyses has been on single nucleotide variants (SNVs), with the contribution of small insertions and deletions (indels) less well characterised. We investigated whether the frameshift nature of indel mutations, which create novel open reading frames and a large quantity of mutagenic peptides highly distinct from self, might contribute to the immunogenic phenotype. METHODS: We analysed whole-exome sequencing data from 5777 solid tumours, spanning 19 cancer types from The Cancer Genome Atlas...
July 7, 2017: Lancet Oncology
https://www.readbyqxmd.com/read/28693613/cascading-training-the-trainers-in-ophthalmology-across-eastern-central-and-southern-africa
#14
Melanie C Corbett, Wanjiku Mathenge, Marcia Zondervan, Nick Astbury
BACKGROUND: The Royal College of Ophthalmologists (RCOphth) and the College of Ophthalmology of Eastern Central and Southern Africa (COECSA) are collaborating to cascade a Training the Trainers (TTT) Programme across the COECSA Region. Within the VISION 2020 Links Programme, it aims to develop a skilled motivated workforce who can deliver high quality eye care. It will train a lead, faculty member and facilitator in 8 countries, who can cascade the programme to local trainers. METHODS: In phase 1 (2013/14) two 3-day courses were run for 16/17 selected delegates, by 3 UK Faculty...
July 10, 2017: Globalization and Health
https://www.readbyqxmd.com/read/28693346/cytomegalovirus-cmv-infection-and-pregnancy-potential-for-improvements-in-australasian-maternity-health-providers-knowledge
#15
A W Shand, W Luk, N Nassar, L Hui, K Dyer, W Rawlinson
PURPOSE: To assess the knowledge, practice and attitudes of maternity clinicians regarding congenital cytomegalovirus (CMV). It is the most common congenital infection, and well-recognized cause of neurodevelopmental disability and hearing loss. New consensus recommendations state all pregnant women and health-care providers should be educated about congenital CMV infection and preventive measures. MATERIALS AND METHODS: An email questionnaire was distributed in October 2015 to specialists, diplomates (general practitioners), and trainees of the Royal Australian New Zealand College of Obstetricians and Gynaecologists (RANZCOG), and Victorian and New South Wales midwives...
July 11, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28687684/transient-neonatal-hypercalcaemia-secondary-to-excess-maternal-vitamin-d-intake-too-much-of-a-good-thing
#16
Adam Reynolds, Susan M O'Connell, Louise Clare Kenny, Eugene Dempsey
We report a case of transient neonatal hypercalcaemia secondary to excess maternal vitamin D intake in pregnancy. Vitamin D insufficiency and deficiency in pregnancy are associated with adverse pregnancy outcomes, but there is no definite benefit to supplementation. The Royal College of Obstetrics and Gynaecology recommends routine supplementation with vitamin D3 400 IU/day, but higher dose preparations usually recommended for the treatment of vitamin D deficiency are readily available over the counter. This case highlights the risks of excess supplementation, especially at higher doses and in women without evidence of vitamin D deficiency...
July 6, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28687408/development-of-postoperative-radiotherapy-for-breast-cancer-uk-consensus-statements-a-model-of-patient-clinical-and-commissioner-engagement
#17
EDITORIAL
D J Bloomfield
No abstract text is available yet for this article.
July 4, 2017: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/28682128/the-effects-of-centralisation-of-vascular-surgical-services-in-the-bath-bristol-and-weston-area-on-the-carotid-endarterectomy-pathway
#18
E Partridge, M Brooks, C Curd, V Davis, C Oates, D McGeeney
Introduction Patients who experience a transient ischaemic attack are at the highest risk of having a subsequent stroke immediately after their symptoms. A carotid endarterectomy should be performed on symptomatic, surgically suitable patients who present with a greater than 50% North American Symptomatic Carotid Endarterectomy Trial stenosis of the internal carotid artery within 2 weeks of their symptoms. This study aimed to determine whether the effectiveness of the carotid endarterectomy pathway has been impacted by the centralisation of vascular surgical services in the Bath, Bristol and Weston area...
July 6, 2017: Annals of the Royal College of Surgeons of England
https://www.readbyqxmd.com/read/28681968/publication-rate-of-general-surgery-abstracts-presented-at-the-royal-australasian-college-of-surgeons-annual-scientific-congress
#19
Masoomeh Khajehnoori, Douglas Stupart, David Watters
BACKGROUND: A commonly used metric for evaluating the quality and impact of presentations at a scientific meeting is the frequency with which the findings presented are published as full research papers in peer-reviewed journals. The purpose of this study was to determine the full article publication rates of abstract presentations for General Surgery and related sub-specialities at the Royal Australasian College of Surgeons Annual Scientific Congress (RACS ASC) from 2010 to 2014. METHODS: All General Surgical (including its sub-speciality groups) abstracts presented at the RACS ASC from 2010 to 2014 were identified from the ANZ Journal of Surgery...
July 6, 2017: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/28681452/views-of-the-obstetric-profession-on-non-invasive-prenatal-testing-in-aotearoa-new-zealand-a-national-survey
#20
Sara K Filoche, Beverley Lawton, Angela Beard, Peter Stone
BACKGROUND: Non-invasive prenatal testing (NIPT) has been available in Aotearoa New Zealand (NZ) for approximately four years. It is likely to be introduced into the publicly funded prenatal screening service. AIM: To explore obstetrician use and views of NIPT, with consideration to its implementation into screening services for Down syndrome and other conditions. METHODS: An anonymous online survey combining Likert scales and free text was designed to assess current practice, knowledge, ethical considerations, counselling and views toward public funding of NIPT...
July 6, 2017: Australian & New Zealand Journal of Obstetrics & Gynaecology
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