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https://www.readbyqxmd.com/read/28324484/sodium-glucose-co-transporter-2-sglt2-inhibitor-comparing-trial-data-and-real-world-use
#1
Andrew McGovern, Michael Feher, Neil Munro, Simon de Lusignan
INTRODUCTION: The first cardiovascular safety trial in the sodium-glucose co-transporter-2 (SGLT2) inhibitor drug class, the Empagliflozin Cardiovascular Outcomes and Mortality in Type 2 Diabetes (EMPA-REG OUTCOME) trial, demonstrated significant cardiovascular risk reduction with empagliflozin. It is currently not clear what proportions of people with type 2 diabetes (T2DM) have the same high cardiovascular risk as those included in the trial, and will therefore be likely to experience the same cardiovascular benefit...
March 21, 2017: Diabetes Therapy: Research, Treatment and Education of Diabetes and related Disorders
https://www.readbyqxmd.com/read/28322180/operative-landscape-at-canadian-neurosurgery-residency-programs
#2
Michael K Tso, Ayoub Dakson, Syed Uzair Ahmed, Mark Bigder, Cameron Elliott, Daipayan Guha, Christian Iorio-Morin, Michelle Kameda-Smith, Pascal Lavergne, Serge Makarenko, Michael S Taccone, Bill Wang, Alexander Winkler-Schwartz, Tejas Sankar, Sean D Christie
Background Currently, the literature lacks reliable data regarding operative case volumes at Canadian neurosurgery residency programs. Our objective was to provide a snapshot of the operative landscape in Canadian neurosurgical training using the trainee-led Canadian Neurosurgery Research Collaborative. METHODS: Anonymized administrative operative data were gathered from each neurosurgery residency program from January 1, 2014, to December 31, 2014. Procedures were broadly classified into cranial, spine, peripheral nerve, and miscellaneous procedures...
March 21, 2017: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
https://www.readbyqxmd.com/read/28321574/a-report-of-the-first-joint-meeting-of-the-royal-college-of-surgeons-of-england-and-the-japan-surgical-society
#3
Paul O'Flynn, Toshiaki Watanabe
No abstract text is available yet for this article.
March 20, 2017: Surgery Today
https://www.readbyqxmd.com/read/28321183/early-events-in-retinal-degeneration-caused-by-rhodopsin-mutation-or-pigment-epithelium-malfunction-differences-and-similarities
#4
Johnny Di Pierdomenico, Diego García-Ayuso, Isabel Pinilla, Nicolás Cuenca, Manuel Vidal-Sanz, Marta Agudo-Barriuso, María P Villegas-Pérez
To study the course of photoreceptor cell death and macro and microglial reactivity in two rat models of retinal degeneration with different etiologies. Retinas from P23H-1 (rhodopsin mutation) and Royal College of Surgeon (RCS, pigment epithelium malfunction) rats and age-matched control animals (Sprague-Dawley and Pievald Viro Glaxo, respectively) were cross-sectioned at different postnatal ages (from P10 to P60) and rhodopsin, L/M- and S-opsin, ionized calcium-binding adapter molecule 1 (Iba1), glial fibrillary acid protein (GFAP), and proliferating cell nuclear antigen (PCNA) proteins were immunodetected...
2017: Frontiers in Neuroanatomy
https://www.readbyqxmd.com/read/28316797/exploring-professionals-understanding-interpretation-and-implementation-of-the-appropriate-medical-treatment-test-in-the-2007-amendment-of-the-mental-health-act-1983
#5
Benjamin I Perry, Nina Champaneri, Frances Griffiths, Moli Paul, Zoebia Islam, Jorun Rugkåsa, Tom Burns, Peter Tyrer, Michael Crawford, Shoumitro Deb, Swaran P Singh
BACKGROUND: The appropriate medical treatment test (ATT), included in the Mental Health Act (MHA) (1983, as amended 2007), aims to ensure that detention only occurs when treatment with the purpose of alleviating a mental disorder is available. AIMS: As part of the Assessing the Impact of the Mental Health Act (AMEND) project, this qualitative study aimed to assess professionals' understanding of the ATT, and its impact on clinical practice. METHOD: Forty-one professionals from a variety of mental health subspecialties were interviewed...
January 2017: BJPsych Open
https://www.readbyqxmd.com/read/28314546/liaison-psychiatry-professionals-views-of-general-hospital-care-for-patients-with-mental-illness-the-care-of-patients-with-mental-illness-in-the-general-hospital-setting
#6
J Noblett, A Caffrey, T Deb, A Khan, E Lagunes-Cordoba, O Gale-Grant, C Henderson
OBJECTIVE: Explore the experiences of liaison psychiatry professionals, to gain a greater understanding of the quality of care patients with mental illness receive in the general hospital setting; the factors that affect the quality of care; and their insights on interventions that could improve care. METHODS: A survey questionnaire and qualitative in depth interviews were used to collect data. Data collection took place at the Royal College of Psychiatrists Faculty of Liaison Psychiatry Annual conference...
April 2017: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/28299785/should-obese-women-s-access-to-assisted-fertility-treatment-be-limited-a-scientific-and-ethical-analysis
#7
Kelton Tremellen, Dominic Wilkinson, Julian Savulescu
Obesity is associated with a reduction in fertility treatment success and increased risks to mother and child. Therefore guidelines of the Royal Australian and New Zealand College of Obstetricians and Gynaecologists (RANZCOG) suggest that a body mass index exceeding 35 kg/m(2) should be an absolute contraindication to assisted fertility treatment such as in vitro fertilisation IVF. In this paper we challenge the ethical and scientific basis for such a ban. Livebirth rates for severely obese women are reduced by up to 30%, but this result is still far better than that observed for many older women who are allowed access to IVF...
March 16, 2017: Australian & New Zealand Journal of Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/28299774/working-hours-of-obstetrics-and-gynaecology-trainees-in-australia-and-new-zealand
#8
Jade Acton, Paige E Tucker, Max K Bulsara, Paul A Cohen
BACKGROUND: The importance of doctors' working hours has gained significant attention with evidence suggesting long hours and fatigue may compromise the safety and wellbeing of both patients and doctors. This study aims to quantify the working hours of The Royal Australian and New Zealand College of Obstetricians and Gynaecologists (RANZCOG) specialist trainees in order to better inform discussions of working hours and safety within our region. METHODS: An anonymous, online survey of RANZCOG trainees was conducted...
March 15, 2017: Australian & New Zealand Journal of Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/28298640/combined-transplantation-of-human-mesenchymal-stem-cells-and-human-retinal-progenitor-cells-into-the-subretinal-space-of-rcs-rats
#9
Linghui Qu, Lixiong Gao, Haiwei Xu, Ping Duan, Yuxiao Zeng, Yong Liu, Zheng Qin Yin
Retinitis pigmentosa (RP) is one of hereditary retinal diseases characterized by the loss of photoreceptors. Cell transplantation has been clinically applied to treat RP patients. Human retinal progenitor cells (HRPCs) and human bone marrow-derived mesenchymal stem cells (HBMSCs) are the two commonly and practically used stem cells for transplantation. Since combined transplantation could be a promising way to integrate the advantages of both stem cell types, we transplanted HRPCs and HBMSCs into the subretinal space (SRS) of Royal College of Surgeons (RCS) rats...
March 15, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28296012/randomized-trial-of-laparoscopic-cholecystectomy-procedure-specific-consent-form
#10
Jack Crozier, Ann Williams, Steven T F Chan, Graeme Thompson
BACKGROUND: Prior to all surgical procedures, possible risks are outlined to patients during an informed consent discussion, and they are invited to ask questions. Written consent records this discussion and signals a patient's willingness to proceed with surgery. This study aims to improve the documentation of complications discussed during laparoscopic cholecystectomy consent through the introduction of a procedure-specific consent form. METHODS: Phase 1 included a retrospective analysis of possible complications documented on standard consent forms for laparoscopic cholecystectomy...
March 14, 2017: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/28295215/non-technical-skills-of-surgical-trainees-and-experienced-surgeons
#11
H Gostlow, N Marlow, M J W Thomas, P J Hewett, A Kiermeier, W Babidge, M Altree, G Pena, G Maddern
BACKGROUND: In addition to technical expertise, surgical competence requires effective non-technical skills to ensure patient safety and maintenance of standards. Recently the Royal Australasian College of Surgeons implemented a new Surgical Education and Training (SET) curriculum that incorporated non-technical skills considered essential for a competent surgeon. This study sought to compare the non-technical skills of experienced surgeons who completed their training before the introduction of SET with the non-technical skills of more recent trainees...
March 13, 2017: British Journal of Surgery
https://www.readbyqxmd.com/read/28288650/analysis-of-an-international-collaboration-for-capacity-building-of-human-resources-for-eye-care-case-study-of-the-college-college-vision-2020-link
#12
Nyawira Mwangi, Marcia Zondervan, Covadonga Bascaran
BACKGROUND: There is an extreme health workforce shortage in Eastern, Central, and Southern Africa. Shortage of eye care workers impedes effective implementation of prevention of blindness programs. The World Health Organization has identified education, partnership, leadership, financing, and policy as intertwined interventions that are critical to resolving this crisis on the long term. CASE PRESENTATION: The VISION 2020 LINK between the College of Ophthalmology of Eastern, Central, and Southern Africa and the Royal College of Ophthalmologists in the United Kingdom aims to increase the quantity and quality of eye care training in East, Central, and Southern Africa through a focus on five strategic areas: fellowship examination for ophthalmologists, training the trainers, curriculum development for residents in ophthalmology and ophthalmic clinical officers, continuous professional development (CPD), and mentoring program for young ophthalmologists...
March 14, 2017: Human Resources for Health
https://www.readbyqxmd.com/read/28286823/protocol-adherence-for-severe-sepsis-and-septic-shock-management-in-the-emergency-department-a-clinical-audit
#13
Mostafa Alavi-Moghaddam, Ali Anvari, Reaza Soltani Delgosha, Hamid Kariman
INTRODUCTION: Although significant development in the field of medicine is achieved, sepsis is still a major issue threatening humans' lives. This study was aimed to audit the management of severe sepsis and septic shock patients in emergency department (ED) according to the present standard guidelines. METHOD: This is a prospective audit on approaching adult septic patients who were admitted to ED. The audit checklist was created based on the protocols of Surviving Sepsis Campaign and British Royal College recommendations...
2017: Emergency (Tehran, Iran)
https://www.readbyqxmd.com/read/28281956/an-assessment-of-direct-restorative-material-use-in-posterior-teeth-by-american-and-canadian-pediatric-dentists-iii-preferred-level-of-participation-in-decision-making
#14
Rae E Varughese, Paul Andrews, Michael J Sigal, Amir Azarpazhooh
PURPOSE: The purpose of this study was to assess Canadian and American pediatric dentists' preferred level of participation in clinical decision-making. METHODS: A web-based survey was used to collect the opinions of all active Royal College of Dentists of Canada members and American Academy of Pediatric Dentistry members on the use of direct restorative materials in posterior teeth (n equals 4,648; 19.3 percent response rate). The main survey also included a domain to elicit participants' preferred role in clinical decision-making, ranging from an active role (the dentist takes the primary role in decision-making while considering patients/caregivers opinions) to a passive role (the dentist prefers to have the patient guide the decision-making)...
November 15, 2016: Pediatric Dentistry
https://www.readbyqxmd.com/read/28281955/an-assessment-of-direct-restorative-material-use-in-posterior-teeth-by-american-and-canadian-pediatric-dentists-ii-rubber-dam-isolation
#15
Rae E Varughese, Paul Andrews, Michael J Sigal, Amir Azarpazhooh
PURPOSE: The purpose of this study was to assess usage, indications, and contraindications for rubber dam isolation (RDI) by pediatric dentists in Canada and the United States. METHODS: A cross-sectional, web-based, self-administered survey was utilized to collect the opinions of all active pediatric dentist members of the Royal College of Dentists of Canada and the American Academy of Pediatric Dentistry on the use of direct restorative materials in posterior teeth (n equals 4,648; 19...
November 15, 2016: Pediatric Dentistry
https://www.readbyqxmd.com/read/28281954/an-assessment-of-direct-restorative-material-use-in-posterior-teeth-by-american-and-canadian-pediatric-dentists-i-material-choice
#16
Rae E Varughese, Paul Andrews, Michael J Sigal, Amir Azarpazhooh
PURPOSE: The purpose of this study was to assess the preferences of pediatric dentists in Canada and the United States about clinical decision-making related to the placement of direct restorative materials. METHODS: A cross-sectional web-based survey was used to collect the preference of all active pediatric members of the Royal College of Dentists of Canada and the American Academy of Pediatric Dentistry on the use of direct restorative materials in posterior teeth in healthy, developmentally delayed (DD), and medically compromised (MC) children...
November 15, 2016: Pediatric Dentistry
https://www.readbyqxmd.com/read/28271279/an-international-assessment-of-trainee-experience-confidence-and-comfort-in-operative-vaginal-delivery
#17
D A Crosby, A Sarangapani, A Simpson, R Windrim, A Satkunaratnam, M F Higgins
AIM: The aim of this study was to assess Irish and Canadian obstetricians in training ("trainees") experience, confidence, and comfort in performing operative vaginal delivery (OVD). STUDY DESIGN: Trainees in Obstetrics and Gynaecology in the University of Toronto and the Royal College of Physicians of Ireland (RCPI) were invited to participate in an anonymous online survey reviewing experience as primary operator of OVD. Trainee confidence and comfort was self-assessed based upon their last few OVDs...
March 7, 2017: Irish Journal of Medical Science
https://www.readbyqxmd.com/read/28265528/resident-development-via-progress-testing-and-test-marking-an-innovation-and-program-evaluation
#18
Karen Schiff, D Josh Williams, Alim Pardhan, Ian Preyra, Shelly-Anne Li, Teresa Chan
INTRODUCTION: Since 2008, the McMaster University Royal College Emergency Medicine residency training program has run practice Short Answer Question (SAQ) examinations to help residents test their knowledge and gain practice in answering exam-style questions. However, marking this type of SAQ exam is time-consuming. METHODS: To help address this problem, we require that senior residents help mark at least one exam per year alongside faculty members. Examinees' identities are kept anonymous by assigning a random number to each resident, which is only decoded after marking...
January 23, 2017: Curēus
https://www.readbyqxmd.com/read/28262078/health-and-well-being-of-uk-children-in-jeopardy
#19
Nick Evans
A new report from the Royal College of Paediatrics and Child Health (RCPCH) warns that the health and well-being of children is falling behind that of many other European countries.
March 6, 2017: Nursing Children and Young People
https://www.readbyqxmd.com/read/28260265/managing-corneal-foreign-bodies-in-office-based-general-practice
#20
Alison Fraenkel, Lawrence R Lee, Graham A Lee
BACKGROUND: Patients with a corneal foreign body may first present to their general practitioner (GP). Safe and efficacious management of these presentations avoids sight-threatening and eye-threatening complications. Removal of a simple, superficial foreign body without a slit lamp is within The Royal Australian College of General Practitioners' (RACGP's) curriculum and scope of practice. Knowing the rele-vant procedural skills and indications for referral is equally important. OBJECTIVE: The objective of this article is to provide an evidence-based and expert-based guide to the management of corneal foreign bodies in the GP's office...
March 2017: Australian Family Physician
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