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https://www.readbyqxmd.com/read/29471603/-monitoring-disease-activity-how-and-when
#1
REVIEW
Kang Moon Lee
Inflammatory bowel disease (IBD) is a chronic, idiopathic inflammatory disease of gastrointestinal tract with waxing and waning clinical course, which may lead to irreversible bowel damage and a loss of bowel function. Cumulative intestinal damage results in complications such as stricture or fistulae, and eventually a large number of IBD patients undergo surgery. Notably, even during remission period (no clinical symptoms), subclinical inflammation often persists and the disease continues to progress. Therefore, the therapeutic target of IBD has been evolving from symptomatic control to mucosal healing to prevent structural intestinal damage...
February 25, 2018: Korean Journal of Gastroenterology, Taehan Sohwagi Hakhoe Chi
https://www.readbyqxmd.com/read/29471048/new-innovative-method-relating-guided-surgery-to-dental-implant-placement
#2
Marie-Alix Fauroux, Marie De Boutray, Eve Malthiéry, Jacques-Henri Torres
INTRODUCTION: Companies selling dental implant guided systems mostly offer similar surgical guides. The purpose of this paper is to present an innovative guided surgery system which originality lies in its guidance device, and to report the author's experience in using this system for dental implant surgery. TECHNICAL PROTOCOL: Two parallel tubes on either side of the drilling axis guide the successive drills and the implant placement. As a result of the lateral guidance, there is no friction of the drills on the surgical guide which would damage it or contaminate the drilling hole with particles torn out from the guide...
February 19, 2018: Journal of Stomatology, Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29468206/severe-visual-loss-and-recovery-post-trabeculectomy-a-case-report
#3
Sana' Muhsen
Purpose: Glaucoma is a progressive optic neuropathy and a leading cause of blindness. Neural losses from glaucoma are irreversible, and so the aim of glaucoma treatment is to slow progression and minimize the risk of further damage. Visual loss post filtration surgery in patients with advanced glaucomatous optic nerve damage is a rare but dreaded complication. Functional improvement is not expected. We report the case of a patient who experienced a significant loss of vision following glaucoma surgery that was followed by late visual recovery...
June 2018: American Journal of Ophthalmology Case Reports
https://www.readbyqxmd.com/read/29466116/acute-effects-of-low-level-laser-therapy-on-patients-functional-capacity-in-the-postoperative-period-of-coronary-artery-bypass-graft-surgery-a-randomized-crossover-placebo-controlled-trial
#4
Cinara Stein, Rafael Oliveira Fernandes, Aline Paula Miozzo, Christian Correa Coronel, Bruno Manfredini Baroni, Adriane Belló-Klein, Rodrigo Della Méa Plentz
OBJECTIVE: The aim of this study was to evaluate the acute effects of low-level laser therapy (LLLT) on the functional capacity to exercise tested by incremental shuttle walking test (ISWT) after coronary artery bypass graft (CABG) surgery. METHODS: Fifteen male patients (60 ± 9 years) were crossed over during the experiment, to compare the outcomes after active LLLT and placebo LLLT treatments. LLLT (850 nm, 200 mW, 30 J to each point, resulting in a total of 240 J per quadriceps muscle), using a multidiode cluster (five spots; 6 J/spot) in eight points per leg was performed 3 min before the ISWT...
February 21, 2018: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/29462714/alterations-of-conjunctival-glycocalyx-and-microcirculation-in-non-septic-critically-ill-patients
#5
Andrius Pranskunas, Tomas Tamosuitis, Neringa Balciuniene, Diana Damanskyte, Edvin Sneider, Astra Vitkauskiene, Edmundas Sirvinskas, Vidas Pilvinis, E Christiaan Boerma
As of now the relationship between glycocalyx degradation and microcirculatory perfusion abnormalities in non-septic critical ill patients is unclear. In addition, conjunctival sidestream dark field-imaging for the purpose of glycocalyx thickness estimation has never been performed. We aimed to investigate whether changes in glycocalyx thickness in non-septic patients are associated with microcirculatory alterations in conjunctival and sublingual mucosa. In this single-centre prospective observational study, using techniques for direct in-vivo observation of the microcirculation, we performed a single measurement of microcirculatory perfusion parameters and visualized glycocalyx thickness in both ocular conjunctiva and sublingual mucosa in mixed cardio surgical (n = 18) and neurocritical patients (n = 27) and compared these data with age-matched healthy controls (n = 20)...
February 17, 2018: Microvascular Research
https://www.readbyqxmd.com/read/29460178/a-cooperation-of-catheters-and-guidewires-based-novel-remote-controlled-vascular-interventional-robot
#6
Xianqiang Bao, Shuxiang Guo, Nan Xiao, Youxiang Li, Cheng Yang, Yuhua Jiang
Remote-controlled vascular interventional robots (RVIRs) are being developed to increase the overall accuracy of surgical operations and reduce the occupational risks of intervening physicians, such as radiation exposure and chronic neck/back pain. Several RVIRs have been used to operate catheters or guidewires accurately. However, a lack of cooperation between the catheters and guidewires results in the surgeon being unable to complete complex surgery by propelling the catheter/guidewire to the target position...
February 19, 2018: Biomedical Microdevices
https://www.readbyqxmd.com/read/29457388/-case-control-study-of-therapeutic-effects-between-extreme-lateral-interbody-fusion-and-conventional-posterior-operation-for-the-treatment-of-upper-lumbar-disc-herniation
#7
Can-Hua Xu, Zeng-Hui Wu, Rong-Chun Chen, Hong-Fa Zhong, Qing-Shun Zhang, Ning Liu, Bi Zhang
OBJECTIVE: To evaluate the clinical outcomes between extreme lateral interbody fusion and conventional posterior operation in the treatment of upper lumbar disc herniation. METHODS: Among 60 patients with upper lumbar disc herniation were treated with extreme lateral interbody fusion(XLIF) or conventional posterior operation from June 2010 to December 2014, 30 patients(19 males and 11 females) were treated with XLIF (XLIF group); and the other 30 patients(17 males and 13 females) were treated with conventional posterior operation (conventional group)...
November 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29451996/foveal-avascular-zone-area-changes-analyzed-using-oct-angiography-after-successful-rhegmatogenous-retinal-detachment-repair
#8
Je Moon Woo, Yo Sep Yoon, Jong Eun Woo, Jung Kee Min
PURPOSE: To investigate foveal avascular zone (FAZ) area after surgery in patients with rhegmatogenous retinal detachment (RRD) that involved or uninvolved the macula, and to evaluate the correlation between FAZ area and visual outcomes using swept-source optical coherence tomography angiography (OCTA). MATERIALS AND METHODS: This retrospective case-control study included 34 eyes (34 patients) with recent onset RRD that were successfully repaired with a single, uncomplicated surgical procedure (pars plana vitrectomy with gas tamponade)...
February 16, 2018: Current Eye Research
https://www.readbyqxmd.com/read/29451642/damage-control-surgery-are-we-losing-control-over-indications
#9
Silvânia Klug Pimentel, Tulio Rucinski, Melina Paula DE Araújo Meskau, Guilherme Pasquini Cavassin, Nathan Harmuch Kohl
OBJECTIVE: to analyze the surgeons' subjective indications for damage control surgery, correlating with objective data about the patients' physiological state at the time the surgery was chosen. METHODS: we carried out a prospective study between January 2016 and February 2017, with 46 trauma victims who were submitted to damage control surgery. After each surgery, we applied a questionnaire to the attending surgeon, addressing the motivations for choosing the procedure...
2018: Revista do Colégio Brasileiro de Cirurgiões
https://www.readbyqxmd.com/read/29451523/-towards-new-therapeutic-paradigms-beyond-symptom-control-in-the-management-of-inflammatory-bowel-diseases
#10
Stefano Festa, Giulia Zerboni, Annalisa Aratari, Riccardo Ballanti, Claudio Papi
Inflammatory bowel diseases, Crohn's disease and ulcerative colitis are chronic relapsing conditions that may result in progressive bowel damage, high risk of complications, surgery and permanent disability. The conventional therapeutic approach for inflammatory bowel diseases is based mainly on symptom control. Unfortunately, a symptom-based therapeutic approach has little impact on major long-term disease outcomes. In other chronic disabling conditions such as diabetes, hypertension and rheumatoid arthritis, the development of new therapeutic approaches has led to better outcomes...
January 2018: Recenti Progressi in Medicina
https://www.readbyqxmd.com/read/29447379/acute-exercise-is-not-cardioprotective-and-may-induce-apoptotic-signalling-in-heart-surgery-a-randomized-controlled-trial
#11
Benedikte T Smenes, Fredrik H Bækkerud, Katrine H Slagsvold, Erlend Hassel, Martin Wohlwend, Maria Pinho, Morten Høydal, Ulrik Wisløff, Øivind Rognmo, Alexander Wahba
OBJECTIVES: During open-heart surgery, the myocardium experiences ischaemia-reperfusion injury. A single bout of moderate, 30-min exercise induces preconditioning and protects the heart from ischaemia-reperfusion injury in rats, but this has never been investigated in humans. We aimed to investigate whether 1 bout of moderate exercise 24 h prior to surgery protects against mitochondrial and cardiac damage. METHODS: Patients scheduled for elective coronary artery bypass were eligible for this pilot study...
February 13, 2018: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29443058/two-photon-intravital-imaging-of-leukocytes-during-the-immune-response-in-lipopolysaccharide-treated-mouse-liver
#12
Sang A Park, Young Ho Choe, Sung Hwan Lee, Young-Min Hyun
Sepsis is a type of severe infection that can cause organ failure and tissue damage. Although the mortality and morbidity rates associated with sepsis are extremely high, no direct treatment or organ-related mechanism has been examined in detail in real time. The liver is the key organ that manages toxins and infections in the human body. Herein, we aimed to perform intravital imaging of mouse liver after induction of endotoxemia in order to track the motility of immune cells, such as neutrophils and liver capsular macrophages (LCMs)...
February 6, 2018: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29442539/platelets-in-wound-healing-and-regenerative-medicine
#13
Julia Etulain
Although platelets are widely recognized as having a critical role in primary hemostasis and thrombosis, increasing experimental and clinical evidence identifies these enucleated cells as relevant modulators of other physiopathological processes including inflammation and tissue regeneration. These phenomena are mediated through the release of growth factors, cytokines, and extracellular matrix modulators that sequentially promote (i) revascularization of damaged tissue through the induction of migration, proliferation, differentiation, and stabilization of endothelial cells in new blood vessels; (ii) restoration of damaged connective tissue through migration, proliferation, and activation of fibroblasts; and (iii) proliferation and differentiation of mesenchymal stem cells into tissue-specific cell types...
February 14, 2018: Platelets
https://www.readbyqxmd.com/read/29439762/the-treatment-of-temporomandibular-joint-dislocation
#14
Ulla Prechel, Peter Ottl, Oliver M Ahlers, Andreas Neff
BACKGROUND: The estimated incidence of temporomandibular joint dislocation in Germany is at least 25/100 000 per year. A correct diagnosis and the initiation of appropriate treatment without delay are essential if permanent damage to the joint is to be avoided. METHODS: This review is based on pertinent publications retrieved by a systematic search in the PubMed, Cochrane, Embase, and ZB Med databases. RESULTS: The initial search yielded 24 650 hits; duplicates were removed and 136 studies were chosen for further analysis...
February 2, 2018: Deutsches Ärzteblatt International
https://www.readbyqxmd.com/read/29425537/-superior-vena-cava-thrombosis-or-stricture-secondary-to-implanted-central-venous-access-six-cases-of-endovascular-and-direct-surgical-treatment-in-cancer-patients
#15
J M Fichelle, V Baissas, S Salvi, J N Fabiani
Superior vena cava (SVC) stenosis or thrombosis is a well-known complication of central venous catheterization for endocavitary treatments, hemodialysis, or chemotherapy. In cancer patients, these SVC lesions are often symptomatic due to intimal damage and chemotherapy toxicity. We report our experience with six patients treated between 2007 and 2012 via an endovascular approach (n=5) or a direct surgical approach (n=1). All patients had SVC syndrome with facial edema, headache and upper limb edema. In three cases, the catheter was in place when the clinical symptoms occurred...
February 2018: Journal de Médecine Vasculaire
https://www.readbyqxmd.com/read/29424905/study-the-relevance-between-inflammatory-factors-and-estradiol-and-their-association-with-knee-osteoarthritis-in-postmenopausal-women
#16
Y-P Liu, J Li, S-B Xin, J X
OBJECTIVE: To investigate whether serum levels of inflammatory factors and estradiol (E2) are involved in the pathogenesis of postmenopausal women with knee osteoarthritis (OA). PATIENTS AND METHODS: 58 randomly patients diagnosed with postmenopausal knee OA that underwent orthopedic surgery from October 2013 to October 2016 in our hospital were selected. These patients, considered as the experimental group, according to the degree of cartilage damage, were divided into light, medium and heavy groups...
January 2018: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29415505/in-vivo-evaluation-of-cerebral-hemodynamics-and-tissue-morphology-in-rats-during-changing-fraction-of-inspired-oxygen-based-on-spectrocolorimetric-imaging-technique
#17
Afrina Mustari, Takuya Kanie, Satoko Kawauchi, Shunichi Sato, Manabu Sato, Yasuaki Kokubo, Izumi Nishidate
During surgical treatment for cerebrovascular diseases, cortical hemodynamics are often controlled by bypass graft surgery, temporary occlusion of arteries, and surgical removal of veins. Since the brain is vulnerable to hypoxemia and ischemia, interruption of cerebral blood flow reduces the oxygen supply to tissues and induces irreversible damage to cells and tissues. Monitoring of cerebral hemodynamics and alteration of cellular structure during neurosurgery is thus crucial. Sequential recordings of red-green-blue (RGB) images of in vivo exposed rat brains were made during hyperoxia, normoxia, hypoxia, and anoxia...
February 6, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29409711/phosphocreatine-in-cardiac-surgery-patients-a-meta-analysis-of-randomized-controlled-trials
#18
Fang Mingxing, Giovanni Landoni, Alberto Zangrillo, Fabrizio Monaco, Vladimir V Lomivorotov, Cao Hui, Maxim Novikov, Valery Nepomniashchikh, Evgeny Fominskiy
OBJECTIVE: There is experimental evidence that phosphocreatine (PCr) can decrease ischemia/reperfusion injury of the heart. The authors investigated if PCr would improve heart performance as compared with standard treatment in cardiac surgery. DESIGN: Meta-analysis of randomized controlled trials. SETTING: Hospitals. PARTICIPANTS: Adult and pediatric patients undergoing cardiac surgery. INTERVENTIONS: The ability of PCr to improve cardiac outcomes as compared with standard treatment was investigated...
July 24, 2017: Journal of Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/29408682/neurochemical-changes-in-unilateral-cerebralhemisphere-during-the-subacute-stage-of-focal-cerebral-ischemia-reperfusion-in-rats-an-ex-vivo-1h-magnetic-resonance-spectroscopy-study
#19
Qun Huang, Chen Li, Nengzhi Xia, Liangcai Zhao, Dan Wang, Yunjun Yang, Hongchang Gao
Understanding the subacute may shed light on the mechanism of cerebral ischemia. The present study aimed to explore metabolic features underlying subacute stage of ischemia-reperfusion injury and developing effective treatments. Rats were divided into three groups: the permanent middle cerebral artery occlusion (pMCAO), transient cerebral focal ischemia (tMCAO) and sham group. Evaluation of animal models was performed by the neurological deficit, MR images and pathological morphological abnormality. To elucidate metabolic changes, we conducted a comparative analysis of metabolic composition of unilateral brain tissue using 1H nuclear magnetic resonance spectroscopy...
January 31, 2018: Brain Research
https://www.readbyqxmd.com/read/29408285/management-of-inferior-vena-caval-injury-repair-or-ligation-a-propensity-score-matching-analysis-using-the-national-trauma-data-bank
#20
Shokei Matsumoto, Kyoungwon Jung, Alan Smith, Raul Coimbra
BACKGROUND: Ligation may be used as part of damage control surgery under critical conditions following inferior vena cava (IVC) injury. IVC ligation could potentially yield greater survival benefit compared to repair following injury. We hypothesized that ligation significantly improve the outcome compared to repair. STUDY DESIGN: The National Trauma Data Bank (NTDB) dataset for 2007-2014 was reviewed. Eligible patients included those sustaining IVC injury who underwent surgical ligation or repair...
February 2, 2018: Journal of the American College of Surgeons
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