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Coronary artery calcium scoring

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https://www.readbyqxmd.com/read/27916431/2016-scct-str-guidelines-for-coronary-artery-calcium-scoring-of-noncontrast-noncardiac-chest-ct-scans-a-report-of-the-society-of-cardiovascular-computed-tomography-and-society-of-thoracic-radiology
#1
Harvey S Hecht, Paul Cronin, Michael J Blaha, Matthew J Budoff, Ella A Kazerooni, Jagat Narula, David Yankelevitz, Suhny Abbara
The Society of Cardiovascular Computed Tomography (SCCT) and the Society of Thoracic Radiology (STR) have jointly produced this document. Experts in this subject have been selected from both organizations to examine subject-specific data and write this guideline in partnership. A formal literature review, weighing the strength of evidence has been performed. When available, information from studies on cost was considered. Computed tomography (CT) acquisition, CAC scoring methodologies and clinical outcomes are the primary basis for the recommendations in this guideline...
November 10, 2016: Journal of Cardiovascular Computed Tomography
https://www.readbyqxmd.com/read/27913900/bone-mineral-density-of-extremities-is-associated-with-coronary-calcification-and-biopsy-verified-vascular-calcification-in-living-donor-renal-transplant-recipients
#2
Zhimin Chen, Jia Sun, Mathias Haarhaus, Peter Barany, Lars Wennberg, Jonaz Ripsweden, Torkel B Brismar, Bengt Lindholm, Annika Wernerson, Magnus Söderberg, Peter Stenvinkel, Abdul Rashid Qureshi
Chronic kidney disease (CKD) mineral and bone disorders (CKD-MBD) may lead to low bone mineral density (BMD) and vascular calcification (VC), but links to the latter are unclear. Here we investigated associations between BMD, coronary artery calcium (CAC) scores, and histological signs of VC in end-stage renal disease (ESRD) patients undergoing living-donor kidney transplantation (LD-Rtx). In 66 ESRD patients (median age 45 years, 68% males), BMD (by dual-energy X-ray absorptiometry, DXA), CAC score (by computed tomography, CT; n = 54), and degree of VC score (graded by histological examination of epigastric artery specimens collected at LD-Rtx; n = 55) were assessed at the time of LD-Rtx...
December 2, 2016: Journal of Bone and Mineral Metabolism
https://www.readbyqxmd.com/read/27913107/the-influence-of-iterative-reconstruction-on-coronary-artery-calcium-scoring-phantom-and-clinical-studies
#3
Seitaro Oda, Daisuke Utsunomiya, Takeshi Nakaura, Yoshinori Funama, Hideaki Yuki, Masafumi Kidoh, Kenichiro Hirata, Narumi Taguchi, Keiichi Honda, Hiroko Takaoka, Yuji Iyama, Kazuhiro Katahira, Katsuo Noda, Shuichi Oshima, Shinichi Tokuyasu, Yasuyuki Yamashita
RATIONALE AND OBJECTIVES: We compared the effect of iterative model reconstruction (IMR), filtered back projection (FBP), and hybrid iterative reconstruction (HIR) on coronary artery calcium (CAC) scoring. MATERIALS AND METHODS: CAC scans of 30 consecutive patients (18 men and 12 women, age 70.1 ± 12.2 years) were reconstructed with FBP, HIR, and IMR, and the image noise was measured on all images. Two radiologists independently measured the CAC scores using semiautomated software, and interobserver agreement was evaluated...
November 29, 2016: Academic Radiology
https://www.readbyqxmd.com/read/27906915/the-value-of-ct-cardiac-angiography-and-ct-calcium-score-testing-in-a-modern-cardiology-service-in-new-zealand-a-report-of-a-single-centre-eight-year-experience-from-5-237-outpatient-procedures
#4
Chris Ellis, Greg Gamble, Colin Edwards, Niels van Pelt, Ruvin Gabriel, Boris Lowe, Jonathan Christiansen, Andrew To, Helen Winch, Mark Osborne, John Ormiston, Malcolm Legget
BACKGROUND: Computed tomographic (CT) cardiac angiography is of increasing value in several areas of patient management in cardiology. We assessed the ability of CT cardiac angiography to effectively 'rule out' severe coronary stenoses in patients presenting with 'atypical' symptoms and/or an equivocal stress test, which offers a new approach to the management of coronary artery disease. We also examined the use of the CT calcium score test in cardiovascular (CVS) risk assessment. METHODS: From a large single centre (Mercy Hospital) in Auckland, using a prospectively acquired, comprehensive database, we audited the entire eight-year experience of 5,169 patients (7/8/06 to 31/1/14) who underwent 5,237 64-slice computed tomographic (CT) cardiac angiogram or CT calcium score tests (GE Lightspeed scanner)...
December 2, 2016: New Zealand Medical Journal
https://www.readbyqxmd.com/read/27904029/coronary-artery-calcium-and-carotid-artery-intima-media-thickness-and-plaque-clinical-use-in-need-of-clarification
#5
Maryam Zaid, Akira Fujiyoshi, Aya Kadota, Robert D Abbott, Katsuyuki Miura
Atherosclerosis begins in early life and has a long latent period prior to onset of clinical disease. Measures of subclinical atherosclerosis, therefore, may have important implications for research and clinical practice of atherosclerotic cardiovascular disease (ASCVD). In this review, we focus on coronary artery calcium (CAC) and carotid artery intima-media thickness (cIMT) and plaque as many population-based studies have investigated these measures due to their non-invasive features and ease of administration...
December 1, 2016: Journal of Atherosclerosis and Thrombosis
https://www.readbyqxmd.com/read/27903540/greater-volume-but-not-higher-density-of-abdominal-aortic-calcium-is-associated-with-increased-cardiovascular-disease-risk-mesa-multi-ethnic-study-of-atherosclerosis
#6
Nketi I Forbang, Erin D Michos, Robyn L McClelland, Rosemay A Remigio-Baker, Matthew A Allison, Veit Sandfort, Joachim H Ix, Isac Thomas, Dena E Rifkin, Michael H Criqui
BACKGROUND: Abdominal aortic calcium (AAC) and coronary artery calcium (CAC) independently and similarly predict cardiovascular disease (CVD) events. The standard AAC and CAC score, the Agatston method, upweights for greater calcium density, thereby modeling higher calcium density as a CVD hazard. METHODS AND RESULTS: Computed tomography scans were used to measure AAC and CAC volume and density in a multiethnic cohort of community-dwelling individuals, and Cox proportional hazard was used to determine their independent association with incident coronary heart disease (CHD, defined as myocardial infarction, resuscitated cardiac arrest, or CHD death), cardiovascular disease (CVD, defined as CHD plus stroke and stroke death), and all-cause mortality...
November 2016: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/27902619/association-between-plasma-adamts-7-levels-and-severity-of-disease-in-patients-with-stable-obstructive-coronary-artery-disease
#7
Jie Yu, Boda Zhou, Haiyi Yu, Jiangli Han, Ming Cui, Fuchun Zhang, Guisong Wang, Lijun Guo, Wei Gao
The metalloproteinase family of a disintegrin and metalloproteinase with thrombospondin motifs-7 (ADAMTS-7) was reported to be a novel locus associated with human coronary artery disease. This study aimed to investigate plasma ADAMTS-7 levels in stable obstructive CAD patients and elucidate the relationship between plasma ADAMTS-7 levels and the severity of CAD assessed by the Syntax score.This was a single center cross-sectional study performed in 182 CAD patients. ELISA was used to measure plasma ADAMTS-7 levels...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27901176/different-methods-of-calculating-ankle-brachial-index-in-mid-elderly-men-and-women-the-brazilian-longitudinal-study-of-adult-health-elsa-brasil
#8
M Miname, I M Bensenor, P A Lotufo
The ankle-brachial index (ABI) is a marker of subclinical atherosclerosis related to health-adverse outcomes. ABI is inexpensive compared to other indexes, such as coronary calcium score and determination of carotid artery intima-media thickness (IMT). Our objective was to identify how the ABI can be applied to primary care. Three different methods of calculating the ABI were compared among 13,921 men and women aged 35 to 74 years who were free of cardiovascular diseases and enrolled in the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil)...
2016: Brazilian Journal of Medical and Biological Research, Revista Brasileira de Pesquisas Médicas e Biológicas
https://www.readbyqxmd.com/read/27900990/prognostic-value-of-gai-s-plaque-score-and-agatston-coronary-artery-calcium-score-for-functionally-significant-coronary-artery-stenosis
#9
Chuang Zhang, Shuang Yang, Lu-Yue Gai, Zhi-Qi Han, Qian Xin, Xiao-Bo Yang, Jun-Jie Yang, Qin-Hua Jin
BACKGROUND: The prognostic values of the coronary computed tomography angiography (CCTA) score for predicting future cardiovascular events have been previously demonstrated in numerous studies. However, few studies have used the rich information available from CCTA to detect functionally significant coronary lesions. We sought to compare the prognostic values of Gai's plaque score and the coronary artery calcium score (CACS) of CCTA for predicting functionally significant coronary lesions, using fractional flow reserve (FFR) as the gold standard...
2016: Chinese Medical Journal
https://www.readbyqxmd.com/read/27884729/rationale-and-design-of-the-coronary-artery-calcium-consortium-a-multicenter-cohort-study
#10
Michael J Blaha, Seamus P Whelton, Mahmoud Al Rifai, Zeina A Dardari, Leslee J Shaw, Mouaz H Al-Mallah, Kuni Matsushita, John A Rumberger, Daniel S Berman, Matthew J Budoff, Michael D Miedema, Khurram Nasir
BACKGROUND: Although coronary artery calcium (CAC) has been investigated for over two decades, there is very limited data on the association of CAC with cause of death. The CAC Consortium is a large ongoing multi-center observational cohort of individuals who underwent non-contrast cardiac-gated CAC testing and systematic, prospective, long-term follow-up for mortality with ascertainment of cause of death. METHODS: Four participating institutions from three states within the US (California, Minnesota, and Ohio) have contributed individual-level patient data to the CAC Consortium (spanning years 1991-2010)...
November 11, 2016: Journal of Cardiovascular Computed Tomography
https://www.readbyqxmd.com/read/27883980/progression-of-coronary-artery-calcium-in-japanese-american-men-and-white-men-in-the-era-jump-study
#11
Vasudha Ahuja, Kamal Masaki, Abhishek Vishnu, Lei Ye, Bradley Wilcox, Christina Wassel, Akira Fujiyoshi, Emma J M Barinas-Mitchell, Katsuyuki Miura, Hirotsuga Ueshima, Beatriz L Rodriguez, Daniel Edmundowicz, Akira Sekikawa
BACKGROUND: Progression of coronary artery calcium (CAC) is associated with increased risk of coronary heart disease (CHD) and is reported to be greater in whites than blacks, Hispanics, and Chinese in the US. Our objective was to compare progression of CAC between Japanese Americans and whites. METHODS: Population-based sample of 303 Japanese American men and 310 white men aged 40-49years, free of clinical cardiovascular disease at baseline, were examined for CAC at baseline (2004-2007) and follow-up (2008-2013)...
November 14, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27882428/progression-of-noncalcified-and-calcified-coronary-plaque-by-ct-angiography-in-sle
#12
Aisha Khan, Armin Arbab-Zadeh, Adnan N Kiani, Laurence S Magder, Michelle Petri
Premature coronary artery disease remains the major cause of late death in systemic lupus erythematosus (SLE). Coronary artery calcium (CAC) represents an advanced stage of atherosclerosis, whereas noncalcified coronary atherosclerotic plaque (NCP) typically is more prone to trigger acute coronary events. The aim of this study was to assess the stability of NCP over time and identify factors associated with changes in NCP in patients with SLE. CT coronary angiography and calcium scanning were performed at baseline and follow-up in thirty-six SLE patients...
November 23, 2016: Rheumatology International
https://www.readbyqxmd.com/read/27882224/correlation-between-serum-parathyroid-hormone-levels-and-coronary-artery-calcification-in-patients-without-renal-failure
#13
Gang-Yong Wu, Bai-Da Xu, Ting Wu, Xiao-Ying Wang, Tian-Xiao Wang, Xiao Zhang, Xiao Wang, Yang Xia, Gang-Jun Zong
The aim of the present study was to investigate the correlation between serum parathyroid hormone (PTH) levels and coronary artery calcification (CAC) in patients without renal failure, as well as to determine independent risk factors of CAC score (CACS). A total of 157 patients who underwent coronary computed tomography angiographic examination at the 101th Hospital of the People's Liberation Army between December 2013 and February 2015 were retrospectively evaluated. The correlation between PTH levels and CACS was determined using a Pearson correlation analysis...
November 2016: Biomedical Reports
https://www.readbyqxmd.com/read/27882093/atherosclerotic-coronary-artery-disease-the-accuracy-of-measures-to-diagnose-preclinical-atherosclerosis
#14
Xianchi Li, Min Liu, Rongrong Sun, Yi Zeng, Shuang Chen, Peiying Zhang
Different methods can be used to diagnose early pre-clinical stage atherosclerosis. The present study was carried out to evaluate the efficiency of these methods. Measures including carotid intima-media thickness (CIMT), pulse wave velocity (PWV), and coronary calcium score (CCS) were evalutated for the detection of coronary artery disease (CAD). We studied the clinical and biochemical profiles of individuals with non-CAD and CAD to assess measures of pre-clinical atherosclerosis. The association between CIMT, PWV and CCS on the one hand, and the coronary atherosclerosis on the other, was studied...
November 2016: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/27873500/impact-of-diltiazem-alone-versus-diltiazem-with-nitrate-on-five-year-clinical-outcomes-in-patients-with-significant-coronary-artery-spasm
#15
Taeshik Park, Ji Young Park, Seung Woon Rha, Hong Seog Seo, Byoung Geol Choi, Se Yeon Choi, Jae Kyeong Byun, Sang Ho Park, Eun Jin Park, Jah Yeon Choi, Sung Hun Park, Jae Joong Lee, Sunki Lee, Jin Oh Na, Cheol Ung Choi, Hong Euy Lim, Jin Won Kim, Eung Ju Kim, Chang Gyu Park, Dong Joo Oh
PURPOSE: Calcium channel blockers diltiazem and nitrate have been used as selective coronary vasodilators for patients with significant coronary artery spasm (CAS). However, no study has compared the efficacy of diltiazem alone versus diltiazem with nitrate for long-term clinical outcomes in patients with CAS. MATERIALS AND METHODS: A total of 2741 consecutive patients without significant coronary artery disease with positive CAS by acetylcholine (Ach) provocation test between November 2004 and May 2014 were enrolled...
January 2017: Yonsei Medical Journal
https://www.readbyqxmd.com/read/27873499/assessment-of-coronary-artery-calcium-scoring-for-statin-treatment-strategy-according-to-acc-aha-guidelines-in-asymptomatic-korean-adults
#16
Donghee Han, Bríain Ó Hartaigh, Ji Hyun Lee, Asim Rizvi, Hyo Eun Park, Su Yeon Choi, Jidong Sung, Hyuk Jae Chang
PURPOSE: The 2013 American College of Cardiology (ACC)/American Heart Association (AHA) cholesterol management guidelines advocate the use of statin treatment for prevention of cardiovascular disease. We aimed to assess the usefulness of coronary artery calcium (CAC) for stratifying potential candidates of statin use among asymptomatic Korean individuals. MATERIALS AND METHODS: A total of 31375 subjects who underwent CAC scoring as part of a general health examination were enrolled in the current study...
January 2017: Yonsei Medical Journal
https://www.readbyqxmd.com/read/27870948/hba1c-increase-is-associated-with-higher-coronary-and-peripheral-atherosclerotic-burden-in-non-diabetic-patients
#17
Roberto Scicali, Philippe Giral, Antonio Gallo, Antonino Di Pino, Agata Maria Rabuazzo, Francesco Purrello, Philippe Cluzel, Alban Redheuil, Eric Bruckert, David Rosenbaum
BACKGROUND AND AIMS: Prediabetes is associated with an increased risk of developing diabetes and cardiovascular disease. Our objective was to examine the cardiovascular (CV) risk profile of non-diabetic patients with and without prediabetes according to HbA1c, using macroangiopathic imaging biomarkers. METHODS: Our population consisted of 272 non diabetic patients aged between 40 and 70 years, with a normal fasting plasma glucose (FPG <5.6 mmol/L) and at least 1 CV risk factor...
November 4, 2016: Atherosclerosis
https://www.readbyqxmd.com/read/27867875/coronary-artery-calcium-scoring-is-a-better-predictor-of-cardiac-risk-in-subclinical-hypothyroidism-patients-with-low-risk-framingham-score
#18
Rajesh Verma, Ashish Verma, Piyush Gupta, N K Agrawal
CONTEXT: Overt hypothyroidism accelerates the cardiovascular disease. Subclinical hypothyroidism (SCH), being considered as a preclinical state, impacts on cardiovascular status is not clear. AIMS: This study was aimed at assessing cardiac risk stratification by Framingham risk scoring (FRS) and coronary coronary artery calcium score (CACS) by noncontrast cardiac computed tomography in SCH. STUDY DESIGN: Observational study. SUBJECTS AND METHODS: We enrolled thirty treatment-naive SCH patients (aged 30-60 years with no serious concurrent medical conditions), thirty euthyroid (age, sex, and body mass index-matched) controls, and ten healthy controls...
November 2016: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/27861721/long-term-hormone-replacement-therapy-is-associated-with-low-coronary-artery-calcium-levels-in-a-cohort-of-older-women-the-age-gene-environment-susceptibility-reykjavik-study
#19
Adalsteinn Gudmundsson, Thor Aspelund, Gunnar Sigurdsson, Tamara Harris, Lenore J Launer, Vilmundur Gudnason, Helgi Jonsson
OBJECTIVES: To assess the relationship between hormone replacement therapy (HRT) and coronary artery calcium (CAC). DESIGN: Cross-sectional. SETTING: Established population-based cohort in Reykjavik, Iceland. PARTICIPANTS: Women (mean age 76 ± 5) who had completed questionnaires on HRT use (N = 2,867). MEASUREMENTS: Coronary artery calcium assessed using computed tomography was the outcome variable and was compared between women with history of HRT and those who had never used HRT and analyzed according to age, length of use, and time after menopause that HRT was initiated...
November 11, 2016: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/27860212/alcohol-and-dietary-factors-associate-with-gut-integrity-and-inflammation-in-hiv-infected-adults
#20
A R Webel, A Sattar, N T Funderburg, B Kinley, C T Longenecker, D Labbato, Sm Khurshid Alam, G A McComsey
OBJECTIVES: HIV-infected adults have heightened monocyte activation and inflammation, at least partially as a consequence of altered gut integrity. The role of dietary factors in microbial translocation and inflammation and their downstream effect on markers of cardiovascular disease (CVD) have not been explored. Our purpose was to describe the longitudinal dietary patterns of HIV-infected adults, and to examine the relationship between dietary intake, gut integrity, inflammation and subclinical markers of CVD in HIV-infected adults...
November 9, 2016: HIV Medicine
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