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Coronary artery calcium scoring

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https://www.readbyqxmd.com/read/29343464/cardiorespiratory-fitness-coronary-artery-calcium-and-cardiovascular-disease-events-in-a-cohort-of-generally-healthy-middle-aged-men-results-from-the-cooper-center-longitudinal-study
#1
Nina B Radford, Laura F DeFina, David Leonard, Carolyn E Barlow, Benjamin L Willis, Larry W Gibbons, Susan C Gilchrist, Amit Khera, Benjamin D Levine
Background -A robust literature demonstrates that coronary artery calcification (CAC) and cardiorespiratory fitness (CRF) are independent predictors of cardiovascular disease (CVD) events. Much less is known about the joint associations of CRF and CAC with CVD risk. In the setting of high CAC, high versus low CRF has been associated with decreased CVD events. The goal of this study was to assess the impact of continuous levels of CRF on CVD risk in the setting of increasing CAC burden. Methods -We studied 8,425 men without clinical CVD who underwent preventive medicine examinations that included an objective measurement of CRF and CAC between 1998-2007...
January 17, 2018: Circulation
https://www.readbyqxmd.com/read/29321389/aortic-root-calcification-score-as-an-independent-factor-for-predicting-major-adverse-cardiac-events-in-familial-hypercholesterolemia
#2
Hirofumi Okada, Hayato Tada, Kenshi Hayashi, Hiroki Kawashima, Tadanori Takata, Kenji Sakata, Atsushi Nohara, Hiroshi Mabuchi, Masakazu Yamagishi, Masa-Aki Kawashiri
AIM: The aims of this study were: 1) to determine whether the accumulation of aortic root calcification (ARC) assessed using coronary computed tomography angiography (CCTA) can predict future cardiovascular events, and 2) to estimate the onset and progression of ARC in patients with familial hypercholesterolemia (FH). METHODS: One hundred thirteen consecutive Japanese patients with heterozygous FH (male=54, mean age=52.1±15.6 years, mean LDL-C=299.0±94.6 mg/dL), without known coronary artery disease, who underwent 64-detector row CCTA were retrospectively evaluated...
January 10, 2018: Journal of Atherosclerosis and Thrombosis
https://www.readbyqxmd.com/read/29311270/revised-framingham-stroke-risk-score-nontraditional-risk-markers-and-incident-stroke-in-a-multiethnic-cohort
#3
Peter Flueckiger, Will Longstreth, David Herrington, Joseph Yeboah
BACKGROUND AND PURPOSE: Limited data exist on the performance of the revised Framingham Stroke Risk Score (R-FSRS) and the R-FSRS in conjunction with nontraditional risk markers. We compared the R-FSRS, original FSRS, and the Pooled Cohort Equation for stroke prediction and assessed the improvement in discrimination by nontraditional risk markers. METHODS: Six thousand seven hundred twelve of 6814 participants of the MESA (Multi-Ethnic Study of Atherosclerosis) were included...
January 8, 2018: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/29305347/maintenance-of-ideal-cardiovascular-health-and-coronary-artery-calcium-progression-in-low-risk-men-and-women-in-the-framingham-heart-study
#4
Shih-Jen Hwang, Oyere Onuma, Joseph M Massaro, Xiaoling Zhang, Yi-Ping Fu, Udo Hoffmann, Caroline S Fox, Christopher J O'Donnell
BACKGROUND: Ideal cardiovascular health (CVH) is associated with a lower risk of cardiovascular disease and freedom from coronary artery calcium (CAC). Prospective data on the association between maintenance of optimal CVH and the progression of subclinical coronary atherosclerosis are limited. We assessed the influence of unfavorable versus favorable CVH on the incidence of CAC progression. METHODS AND RESULTS: The study population consisted of 1119 FHS (Framingham Heart Study) participants who attended the serial FHS MDCT I and MDCT II study (Multi-Detector Computed Tomography) and had a zero Agatston CAC score at baseline...
January 2018: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29291201/sickle-cell-and-alpha-thalassemia-traits-resulting-in-non-atherosclerotic-myocardial-infarction-beyond-coincidence
#5
Lee S Nguyen, Alban Redheuil, Olivier Mangin, Joe-Elie Salem
Alpha-thalassemia trait and sickle trait are not commonly considered risk factors of ischemic heart disease. We report the case of a non-atherosclerotic silent myocardial infarction in a 46-year-old woman, carrier of the alpha-thalassemia trait (homozygous deletion of locus -3.7) combined with sickle cell trait. While the patient was included as healthy volunteer for a metabolic study, we performed cardiac magnetic resonance imagery showing a left ventricle apicolateral myocardial infarction. Coronary computed tomography angiography showed normal coronary arteries with a coronary calcium score of 0...
December 16, 2017: World Journal of Clinical Cases
https://www.readbyqxmd.com/read/29285727/influence-of-heart-rate-on-coronary-calcium-scores-a-multi-manufacturer-phantom-study
#6
N R van der Werf, M J Willemink, T P Willems, R Vliegenthart, M J W Greuter, T Leiner
To evaluate the influence of heart rate on coronary calcium scores (CCS) using a dynamic phantom on four high-end computed tomography (CT) systems from different manufacturers. Artificial coronary arteries were moved in an anthropomorphic chest phantom at linear velocities, corresponding to < 60, 60-75 and > 75 beats per minute (bpm). Data was acquired with routinely used clinical protocols for CCS on four high-end CT systems (CT1-CT4). CCS, quantified as Agatston and mass scores were compared to reference scores at < 60 bpm...
December 28, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/29285725/influence-of-iterative-reconstruction-on-coronary-calcium-scores-at-multiple-heart-rates-a-multivendor-phantom-study-on-state-of-the-art-ct-systems
#7
N R van der Werf, M J Willemink, T P Willems, M J W Greuter, T Leiner
The objective of this study was to evaluate the influence of iterative reconstruction on coronary calcium scores (CCS) at different heart rates for four state-of-the-art CT systems. Within an anthropomorphic chest phantom, artificial coronary arteries were translated in a water-filled compartment. The arteries contained three different calcifications with low (38 mg), medium (80 mg) and high (157 mg) mass. Linear velocities were applied, corresponding to heart rates of 0, < 60, 60-75 and > 75 bpm...
December 28, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/29260893/accuracy-of-coronary-artery-calcium-scoring-with-tube-current-reduction-by-75-using-an-adaptive-iterative-reconstruction-algorithm
#8
Reny Luhur, Joanne D Schuijf, Jügen Mews, Jörg Blobel, Bernd Hamm, Alexander Lembcke
OBJECTIVE: To assess the accuracy of an iterative reconstruction (IR) technique for coronary artery calcium scoring with reduced radiation dose. METHODS: 163 consecutive patients underwent twofold scanning by 320-row detector computed tomography (CT) at 120 kVp. A low-dose scan at 25% tube current but with standard scan length (14 cm) was followed by a standard dose scan with routine tube current but reduced scan length (10 cm). Reduced dose images were constructed using filtered back-projection (FBP) and IR (adaptive iterative dose reduction in 3 dimensions, or AIDR3D)...
December 20, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/29247160/the-proper-use-of-coronary-calcium-score-and-coronary-computed-tomography-angiography-for-screening-asymptomatic-patients-with-cardiovascular-risk-factors
#9
Shee Yen Tay, Po-Yen Chang, Wilson T Lao, Ying Chin Lin, Yi-Han Chung, Wing P Chan
Early detection and treatment of coronary artery disease (CAD) can reduce incidences of acute myocardial infarction. In this study, we determined the proper use of contributing risk factors and coronary artery calcium score (CACS) when screening asymptomatic patients with coronary arterial stenoses using coronary computed tomography angiography (CCTA). We reviewed 934 consecutive patients who received CACS and CCTA between December 2013 and November 2016. At least one cardiovascular disease risk factor was present in each of the 509 asymptomatic participants...
December 15, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29245308/total-parathyroidectomy-with-forearm-auto-transplantation-improves-the-quality-of-life-and-reduces-the-recurrence-of-secondary-hyperparathyroidism-in-chronic-kidney-disease-patients
#10
COMPARATIVE STUDY
Jia-Gen Li, Zhang-Sheng Xiao, Xian-Jie Hu, Yun Li, Xing Zhang, Song-Ze Zhang, Ai-Qin Shan
BACKGROUND: Our study aims to explore the effect of total parathyroidectomy (PTX) with forearm autotransplantation (FAT) on the quality of life and recurrence of secondary hyperparathyroidism (SHPT) in chronic kidney disease patients. METHODS: A total of 104 chronic kidney disease patients with SHPT were enrolled and divided into the PTX (n = 62) and PTX + FAT (n = 42) groups. The operation efficacy was evaluated by analyzing preoperative and postoperative values, including levels of intact parathyroid hormone (iPTH), serum phosphorus, serum calcium, alkaline phosphatase (ALP), calcium-phosphorus product, signs and symptoms, and MOS 36-item short-form health survey (SF-36) scores...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29242656/single-bolus-dose-of-epidural-magnesium-prolongs-the-duration-of-analgesia-in-cardiac-patients-undergoing-vascular-surgeries
#11
Amarja Sachin Nagre, Nagesh Jambure
Background and Aims: Magnesium, a physiological antagonist of calcium and N-methyl-d-aspartate, has a role in the prevention of pain in patients undergoing surgery for peripheral vascular diseases with cardiac comorbidities such as ischaemic heart disease and coronary artery disease. The objective of our study was assessment of effects of epidural magnesium in cardiac patients undergoing vascular surgery. Methods: Sixty patients of either sex American Society of Anesthesiologists physical status III undergoing surgeries for peripheral vascular diseases were enrolled...
October 2017: Indian Journal of Anaesthesia
https://www.readbyqxmd.com/read/29239051/coronary-and-carotid-atherosclerosis-in-asymptomatic-male-marathon-runners
#12
Christof Burgstahler, Hans Cipowicz, Christoph Thomas, Christoph Schabel, Stefanie Mangold, Dominik Ketelsen, Claus D Claussen, Andreas M Niess, Ilias Tsiflikas
The aim of the study was to evaluate the diagnostic accuracy of carotid ultrasound (CU) to predict coronary atherosclerosis in asymptomatic male marathon runners. A total of 49 male marathon runners older than 45 years(mean age 53.3±7.2 years, range 45-74 years) received CU and cardiac CT angiography(CTA) including calcium scoring(CS). Results of CU and CTA were classified binary: 1. Absence of atherosclerosis and 2. presence of atherosclerosis. The extend of atherosclerosis was not primary end-point of the study...
December 14, 2017: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/29225032/calcification-of-thoracic-and-abdominal-aneurysms-is-associated-with-mortality-and-morbidity
#13
Mohammed M Chowdhury, Lukasz P Zieliński, James J Sun, Simon Lambracos, Jonathan R Boyle, Seamus C Harrison, James H F Rudd, Patrick A Coughlin
INTRODUCTION: Cardiovascular events are common in people with aortic aneurysms. Arterial calcification is a recognised predictor of cardiovascular outcomes in coronary artery disease. Whether calcification within abdominal and thoracic aneurysm walls is correlated with poor cardiovascular outcomes is not known. PATIENTS AND METHODS: Calcium scores were derived from computed tomography (CT) scans of consecutive patients with either infrarenal (AAA) or descending thoracic aneurysms (TAA) using the modified Agatston score...
December 7, 2017: European Journal of Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/29220061/comparison-of-carotid-intima-media-thickness-and-coronary-artery-calcium-score-for-estimating-subclinical-atherosclerosis-in-patients-with-fatty-liver-disease
#14
Hyun-Jin Kim, Hyung-Bok Park, Yongsung Suh, Yoon-Hyeong Cho, Eui-Seok Hwang, Deok-Kyu Cho, Tae-Young Choi
INTRODUCTION: Fatty liver disease (FLD) is correlated with cardiovascular disease. Carotid intima-media thickness (CIMT) and coronary artery calcium score (CACS) can noninvasively identify subclinical atherosclerosis and predict risk for cardiovascular events. This study evaluated CIMT and CACS measurements to detect subclinical atherosclerosis in patients with and without FLD. METHODS: Patients who underwent carotid and abdominal ultrasounds as well as cardiac computed tomography (CT) scans were evaluated retrospectively...
December 8, 2017: Cardiovascular Journal of Africa
https://www.readbyqxmd.com/read/29202484/usefulness-of-martin-s-method-for-estimation-of-low-density-lipoprotein-cholesterol-in-coronary-atherosclerosis
#15
Soie Chung
OBJECTIVE: This study was conducted to validate Martin's method in coronary atherosclerosis in comparison with Friedewald's equation. SUBJECTS AND METHODS: A total of 299 participants with a coronary artery calcium score (CACS) ≥ 300 and a serum triglyceride (TG) level < 400 mg/dL at Seoul National University Hospital Healthcare System Gangnam Center, Seoul, Korea were enrolled in this study. The Low-density lipoprotein cholesterol (LDL-C) was directly measured with a homogeneous assay (DLDL) and estimated by both Friedewald's equation (FLDL) and Martin's method (MLDL)...
December 4, 2017: Medical Principles and Practice: International Journal of the Kuwait University, Health Science Centre
https://www.readbyqxmd.com/read/29198984/relation-of-an-echocardiographic-based-cardiac-calcium-score-to-mitral-stenosis-severity-and-coronary-artery-disease-in-patients-with-severe-aortic-stenosis
#16
Siyuan P Sheng, Lucius A Howell, Melissa C Caughey, Michael Yeung, John P Vavalle
Patients with calcific aortic stenosis (AS) often have diffuse cardiac calcification involving the mitral valve apparatus and coronary arteries. We examined the association between global cardiac calcification quantified by a previously validated echocardiographic calcium score (eCS) with the severity of mitral stenosis (MS) and coronary artery disease (CAD) in patients with a clinical diagnosis of severe calcific AS. In this sample of 147 patients (mean age 81 ± 9 years, 50% male), 81 patients (55%) were determined by echocardiography to have some degree of MS...
October 26, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/29174140/relation-of-coronary-artery-calcium-and-extra-coronary-aortic-calcium-to-incident-hypertension-from-the-multi-ethnic-study-of-atherosclerosis
#17
Amer I Aladin, Mahmoud Al Rifai, Shereen H Rasool, Zeina Dardari, Joseph Yeboah, Khurram Nasir, Matthew J Budoff, Bruce M Psaty, Roger S Blumenthal, Michael J Blaha, John W McEvoy
Arterial calcification reflects an atherosclerotic process associated with vascular stiffness. Whether baseline coronary artery calcium (CAC) and extra-coronary calcium (ECC), measured using noncontrast computed tomography imaging, are associated with incident hypertension is poorly understood. We studied participants from the Multi-Ethnic Study of Atherosclerosis without measured or self-reported hypertension at baseline. Incident hypertension was defined by blood pressure criteria (BP, ≥140/90 mmHg), BP medication use, or both, and was assessed at in-person visits...
October 24, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/29171773/fitness-attenuates-the-prevalence-of-increased-coronary-artery-calcium-in-individuals-with-metabolic-syndrome
#18
Elin Ekblom-Bak, Örjan Ekblom, Erika Fagman, Oskar Angerås, Caroline Schmidt, Annika Rosengren, Mats Börjesson, Göran Bergström
Background The association between cardiorespiratory fitness, physical activity and coronary artery calcium (CAC) is unclear, and whether higher levels of fitness attenuate CAC prevalence in subjects with metabolic syndrome is not fully elucidated. The present study aims to: a) investigate the independent association of fitness on the prevalence of CAC, after adjustment for moderate-to-vigorous physical activity and sedentary time, and b) study the possible attenuation of increased CAC by higher fitness, in participants with metabolic syndrome...
January 1, 2017: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/29168268/lifetime-marijuana-use-and-subclinical-atherosclerosis-the-coronary-artery-risk-development-in-young-adults-cardia-study
#19
Reto Auer, Stephen Sidney, David Goff, Eric Vittinghoff, Mark J Pletcher, Norrina B Allen, Jared P Reis, Cora E Lewis, Jeffrey Carr, Jamal S Rana
BACKGROUND AND AIMS: Unlike tobacco, the effect of marijuana smoke on subclinical atherosclerosis, a surrogate measure for cardiovascular disease, is not known. This study aimed to determine the association between lifetime exposure to marijuana and measures of subclinical atherosclerosis in mid-life. DESIGN, SETTING AND PARTICIPANTS: We used data from the US-based Coronary Artery Risk Development in Young Adults (CARDIA) Study, a cohort of black and white men and women aged 18-30 years at baseline in 1985-86, with up to 7 follow-up exams over 25 years...
November 22, 2017: Addiction
https://www.readbyqxmd.com/read/29153576/coronary-artery-calcium-and-long-term%C3%A2-risk-of-death-myocardial%C3%A2-infarction-and-stroke-the-walter-reed-cohort-study
#20
Joshua D Mitchell, Robert Paisley, Patrick Moon, Eric Novak, Todd C Villines
OBJECTIVES: This study aimed to assess the long-term risk of death and atherosclerotic cardiovascular disease (ASCVD) outcomes, including stroke, in a real-world cohort that underwent coronary artery calcium (CAC) scoring. BACKGROUND: Large-scale, long-term studies assessing the independent relationship of CAC for prediction of ASCVD events, to include stroke, in young, low-risk patients are uncommon outside of the clinical trial setting. METHODS: A total of 23,637 consecutive subjects without ASCVD who underwent CAC scoring from 1997 to 2009 were studied...
November 10, 2017: JACC. Cardiovascular Imaging
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