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Faraidoon haghdoost

Faraidoon Haghdoost
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July 2016: Headache
Faraidoon Haghdoost, Mahsa Gharzi, Farough Faez, Elinaz Hosseinzadeh, Mohamadhasan Tajaddini, Laleh Ra Ei, Fatemeh Asgari, Mahboobeh Banihashemi, Samaneh Sadat Masjedi, Alireza Zandifar, Shaghayegh Haghjooy-Javanmard
BACKGROUND: Migraine is a common neurovascular disorder with multifactorial and polygenic inheritance. The aim of this study was to investigate the association of a migraine without aura and Ala379Val polymorphism of lipoprotein-associated phospholipase A2 (Lp-PLA2) gene in the Iranian population. METHODS: In this study, 103 migraine patients and 100 healthy controls were enrolled. DNA samples were extracted and the Ala379Val polymorphism of Lp-PLA2 gene was investigated...
April 3, 2016: Iranian Journal of Neurology
Alireza Zandifar, Samira Soleimani, Niloufar Iraji, Faraidoon Haghdoost, Mohamadhasan Tajaddini, Shaghayegh Haghjooy Javanmard
INTRODUCTION: Migraine is a chronic neurological disorder. Inflammation has a key role in migraine pathophysiology. Urokinase plasminogen activator receptor (uPAR) directly involves in inflammatory conditions by facilitating migration of inflammatory cells to different tissues. The aim of this study was to investigate whether uPAR rs344781, common genetic polymorphism in the uPAR promoter region, might be associated with migraine without aura susceptibility in an Iranian population. METHODS: We enrolled 103 newly diagnosed patients with migraine and 100 healthy controls...
May 2014: Clinical Neurology and Neurosurgery
Alireza Zandifar, Fatemeh Asgari, Faraidoon Haghdoost, Samaneh Sadat Masjedi, Navid Manouchehri, Mahboobeh Banihashemi, Abbas Ghorbani, Mohammad Reza Najafi, Mohammad Saadatnia, Richard B Lipton
INTRODUCTION: MIDAS is a valid and reliable short questionnaire for assessment of headache related disability. Linguistic validation of Persian MIDAS and assessment of psychometric properties between tension type headache (TTH) and migraine were the aims of this study. METHODS: Patients with migraine or TTH were included. At the first visit, we administered a headache symptom questionnaire, MIDAS, and SF-36. Patients filled out MIDAS in second and third visit within three and eight weeks after base line visit...
2014: BioMed Research International
Alireza Zandifar, Samaneh Sadat Masjedi, Mahboobeh Banihashemi, Fatemeh Asgari, Navid Manouchehri, Homa Ebrahimi, Faraidoon Haghdoost, Mohammad Saadatnia
BACKGROUND: There have been few studies on the relation between vitamin D and migraine. We investigated the prevalence of vitamin D deficiency in migraine patients and compared it with a control group. We also evaluated the relationship of vitamin D deficiency with severity of migraine. METHODS: 105 newly diagnosed migraine patients and 110 controls, matched for age, sex, socioeconomic status, education, and sun exposure, were enrolled during the spring of 2011...
2014: BioMed Research International
Alireza Zandifar, Maryam Taheriun, Samira Soleimani, Faraidoon Haghdoost, Mohamadhasan Tajaddini, Shaghayegh Haghjooy Javanmard
BACKGROUND AND OBJECTIVES: Migraine is a multifactorial common neurovascular disease with a polygenic inheritance. Inflammation plays an important part in migraine pathophysiology. C-C chemokine receptor 2 (CCR2) is an important chemokine for monocyte aggregation and transendothelial monocyte migration. The aim of our study was to investigate the association of migraine with CCR2V64Il polymorphism in the Iranian population. METHODS: We assessed 103 patients with newly diagnosed migraine and 100 healthy subjects...
2013: TheScientificWorldJournal
Faraidoon Haghdoost, Mohammad Mehdi Baradaran Mahdavi, Alireza Zandifar, Mohammad Hossein Sanei, Behzad Zolfaghari, Shaghayegh Haghjooy Javanmard
Objectives. The aim of the present study was to evaluate the effect of Pistacia atlantica resin extract on the rat skin burn wound healing. Methods. Thirty-two Wistar rats were divided into four groups and treated by vehicle, 5%, 10%, and 20% concentration of Pistacia atlantica resin extract for 14 days (G1, G2, G3, and G4, resp.). The efficacy of treatment was assessed based on reduction of burn wound size and histological and molecular characteristics. Results. α -Pinene (46.57%) was the main content of essential oil of resin...
2013: Evidence-based Complementary and Alternative Medicine: ECAM
Alireza Zandifar, Mahboobeh Banihashemi, Faraidoon Haghdoost, Samaneh S Masjedi, Navid Manouchehri, Fatemeh Asgari, Mohammad R Najafi, Abbas Ghorbani, Samaneh Zandifar, Mohammad Saadatnia, Michelle K White
OBJECTIVE: Headache Impact Test (HIT-6) measures the impact headaches in a 1-month period. We validated the Persian translation of HIT-6, compared the HIT-6 psychometric analysis between migraine and tension-type headache (TTH) patients, and evaluated the capability of HIT-6 to differentiate between TTH, chronic migraine, and episodic migraine. METHODS: Qualified participants, including 274 patients diagnosed with migraine or TTH, were required to complete HIT-6, SF-36v2, and a symptoms questionnaire on their first visit...
September 2014: Pain Practice: the Official Journal of World Institute of Pain
Alireza Zandifar, Samaneh Sadat Masjedi, Faraidoon Haghdoost, Fatemeh Asgari, Navid Manouchehri, Mahboobeh Banihashemi, Mohammad Reza Najafi, Abbas Ghorbani, Behzad Zolfaghari, Ali Gholamrezaei, Vahid Shaygannejad, Mohammad Saadatnia
BACKGROUND: Migraine-specific quality of life (MSQ) is a valid and reliable questionnaire. Linguistic validation of Persian MSQ questionnaire, analysis of psychometric properties between chronic and episodic migraine patients, and capability of MSQ to differentiate between chronic and episodic migraines were the aims of this study. METHOD: Participants were selected from four different neurology clinics that were diagnosed as chronic or episodic migraine patients...
2013: TheScientificWorldJournal
Mohammad Motaghi, Shaghayegh Haghjooy Javanmard, Faraidoon Haghdoost, Mohamadhasan Tajadini, Mohammad Saadatnia, Laleh Rafiee, Alireza Zandifar
BACKGROUND: Inflammation has a key role in migraine pathophysiology. Vitamin D is an effective anti-inflammatory agent. The aim of this study was to investigate the association between migraine and two vitamin D receptor (VDR) polymorphisms (TaqI and FokI) and also the relationship between VDR polymorphisms and headache severity. METHODS: In this case-control study we assessed 103 patients with newly diagnosed migraine without aura and 100 healthy subjects. Patients filled headache impact test-6 (HIT-6) as a tool to assess headache severity...
2013: BioMed Research International
Shaghayegh Haghjooy Javanmard, Kiandokht Keyhanian, Parisa Loghmani, Amir Abbas Samety, Faraidoon Haghdoost, Laleh Rafiei, Mohammad Talaei, Sedigheh Asgari, Mohammad Hashemi Jazi, Nizal Sarrafzadegan
Heme oxygenase-1 (HO-1) which is a rate-limiting enzyme in heme degradation processes shows a dinucleotide GT repeat in the promoter that alters the level of gene transcription. This study is aimed to assess the association of HO-1 gene promoter polymorphism and metabolic syndrome (MetS). A hundred and fifty two individuals, who were followed in Isfahan Cohort Study since 2001, were enrolled in this study. They consisted of 78 MetS patients and 74 controls without MetS. Blood samples were obtained from all participants and after extracting the genomic DNA, promoter sequence was determined by PCR-based genotyping...
March 2012: Molecular Biology Reports
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