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https://www.readbyqxmd.com/read/28231596/-impact-of-a-senso-motoric-intervention-in-copd-patients-participating-in-an-outpatient-pulmonary-rehabilitation-program-a-randomized-controlled-trial
#1
M Spielmanns, K Müller, N Schott, A Winkler, H Polanski, C Nell, T Boeselt, A R Koczulla, J H Storre, W Windisch, F S Magnet, K Baum
Objective: Exercise training provides a cornerstone of pulmonary rehabilitation (PR) in COPD-patients. However, the components of the training are not yet fully investigated. We conducted a randomized controlled trial to investigate the effectiveness of a sensory-motoric training (SMT) in comparison to a conventional strength training (KT) according to the physical performance. Patients and Methods: 43 COPD patients were randomized and participated either in the intervention group (SMT = 30 minutes SMT per day) or in the control group (KT = 30 minutes KT per day)...
February 23, 2017: Die Rehabilitation
https://www.readbyqxmd.com/read/28231435/impact-of-a-competition-with-two-consecutive-matches-in-a-day-on-physical-performance-in-young-tennis-players
#2
Cesar Gallo-Salazar, Juan Del Coso, David Barbado, Alejandro Lopez-Valenciano, Francisco Javier Santos-Rosa, David Sanz-Rivas, Manuel Moya, Jaime Fernandez-Fernandez
The purpose of this study was to analyze the effects of playing two tennis matches on the same day on physical performance in young tennis players. Twelve well-trained young tennis players took part in a simulated tennis competition consisting of two tennis matches on the same day (morning and afternoon sessions). Before and the day after the competition, physical performance was measured using a battery of countermovement jumps (CMJ), a 10-m sprint, the 5-0-5 agility test, hip, grip and shoulder maximal isometric strength, shoulder range of motion (ROM) and a serve velocity test...
February 23, 2017: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/28230923/predicting-phenotype-from-genotype-improving-accuracy-through-more-robust-experimental-and-computational-modeling
#3
Jonathan Gallion, Amanda Koire, Panagiotis Katsonis, Anne-Marie Schoenegge, Michel Bouvier, Olivier Lichtarge
Computational prediction yields efficient and scalable initial assessments of how variants of unknown significance (VUS) may affect human health. However, when discrepancies between these predictions and direct experimental measurements of functional impact arise, inaccurate computational predictions are frequently assumed as the source. Here we present a methodological analysis indicating that shortcomings in both computational and biological data can contribute to these disagreements. We demonstrate that incomplete assaying of multifunctional proteins can affect the strength of correlations between prediction and experiments; a variant's full impact on function is better quantified by considering multiple assays that probe an ensemble of protein functions...
February 23, 2017: Human Mutation
https://www.readbyqxmd.com/read/28230634/platelet-dysfunction-in-critically-ill-patients
#4
Travis Hase, Sarah Sirajuddin, Patrick Maluso, Raksha Bangalore, Louis DePalma, Babak Sarani
Thrombelastography Platelet Mapping (TEG-PM) allows for measurement of maximal potential clot strength (MA) and strength from stimulation of arachidonic acid (MA-AA) and adenosine disphosphate (MA-ADP) receptors. This study was conducted to assess degree of platelet dysfunction in critically ill adult patients. A retrospective study of critically ill, adult, nontrauma patients in a medical/surgical ICU was conducted from August 2013 to September 2014. All patients who underwent TEG-PM were enrolled. Patients with intracerebral hemorrhage, following cardiac surgery, or without an APACHE II score were excluded...
February 21, 2017: Blood Coagulation & Fibrinolysis: An International Journal in Haemostasis and Thrombosis
https://www.readbyqxmd.com/read/28230346/high-strength-stereolithographic-3d-printed-nanocomposites-graphene-oxide-metastability
#5
Jill Z Manapat, Joey Dacula Mangadlao, Brylee David Buada Tiu, Grace C Tritchler, Rigoberto C Advincula
The weak thermomechanical properties of commercial 3D printing plastics have limited the technology's application mainly to rapid prototyping. In this report, we demonstrate a simple approach that takes advantage of the metastable, temperature-dependent structure of graphene oxide (GO) to enhance the mechanical properties of conventional 3D-printed resins produced by stereolithography (SLA). A commercially available SLA resin was reinforced with minimal amounts of GO nanofillers and thermally annealed at 50 °C and 100 °C for 12 hours...
February 23, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28229937/1-high-definition-transcranial-direct-current-stimulation-to-both-primary-motor-cortices-improves-unimanual-and-bimanual-dexterity
#6
Nils H Pixa, Fabian Steinberg, Michael Doppelmayr
While most research on brain stimulation with transcranial direct current stimulation (tDCS) targets unimanual motor tasks, little is known about its effects on bimanual motor performance. This study aims to investigate the effects of tDCS on unimanual as well as bimanual motor dexterity. We examined the effects of bihemispheric anodal high-definition tDCS (HD-atDCS) on both primary motor cortices (M1) applied concurrent with unimanual and bimanual motor training. We then measured the effects with the Purdue Pegboard Test (PPT) and compared them to a sham stimulation...
February 13, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/28229646/special-nutrition-intervention-is-required-for-muscle-protective-efficacy-of-physical-exercise-in-elderly-people-at-highest-risk-of-sarcopenia
#7
A Molnár, I Jónásné Sztruhár, Á A Csontos, Cs Ferencz, Sz Várbíró, B Székács
Progressive loss of muscle mass and strength is a physiological consequence of aging, and without interventions, it usually deteriorates into sarcopenia. In this study, the hypothesis that combined special nutritional-physiotherapeutical intervention to prevent or reverse this biological deterioration in elderly people was tested. The effects of the regular resistance muscle training (PT, n = 17) alone and the combined exercise + special nutrition therapy containing whey protein and vitamin D (PT + NT, n = 17) were monitored for 3 months in 34 elderly patients (12 men and 22 women; mean age: 66...
September 2016: Physiol Int
https://www.readbyqxmd.com/read/28229575/effects-of-a-low-volume-plyometric-training-in-anaerobic-performance-of-adolescent-athletes
#8
Ari R Assunção, Martim Bottaro, Euler A Cardoso, Daiane P Dantas da Silva, Marcelo Ferraz, Carlos A Vieira, Paulo Gentil
BACKGROUND: Parameters related to the anaerobic capacity and power may be important for the performance of many sports whose skills are related to high-intensity and short- duration efforts. Although plyometric training (PT) has been widely used in the regular strength and conditioning programs of young athletes, its effects on anaerobic performance are still controversial. Therefore, the purpose of the present study was to evaluate the effects of PT in anaerobic performance in young athletes...
February 22, 2017: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/28229573/associations-between-functional-movement-screen-scores-and-performance-variables-in-surf-athletes
#9
Bruno A Ferreira da Silva, Filipe M Clemente, Fernando M Lourenço Martins
BACKGRAUND: Functional Movement Screen (FMS) have been used to assess the movement patterns in daily sports practice. Some associations between FMS scores and physical variables have been found in some sports. Nevertheless, no study was conducted in surf. METHODS: Eighteen surf athletes (11 male) participated in the study (18.3 ± 6.3 y; 60.0 ± 9.6 kg; 168.6 ± 8.1 cm). All participants completed anthropometrics, Knee to Wall test, Functional Movement Screen, Isometric Knee Extension, Handgrip, Squat and Countermovement Jump...
February 22, 2017: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/28229561/children-s-selective-trust-decisions-rational-competence-and-limiting-performance-factors
#10
Jonas Hermes, Tanya Behne, Anna Elisa Bich, Christa Thielert, Hannes Rakoczy
Recent research has amply documented that even preschoolers learn selectively from others, preferring, for example, reliable over unreliable and competent over incompetent models. It remains unclear, however, what the cognitive foundations of such selective learning are, in particular, whether it builds on rational inferences or on less sophisticated processes. The current study, therefore, was designed to test directly the possibility that children are in principle capable of selective learning based on rational inference, yet revert to simpler strategies such as global impression formation under certain circumstances...
February 22, 2017: Developmental Science
https://www.readbyqxmd.com/read/28229532/n-butylidenephthalide-treatment-prolongs-life-span-and-attenuates-motor-neuron-loss-in-sod1-g93a-mouse-model-of-amyotrophic-lateral-sclerosis
#11
Qin-Ming Zhou, Jing-Jing Zhang, Song Li, Sheng Chen, Wei-Dong Le
AIMS: To evaluate the therapeutic effects of n-butylidenephthalide (BP) in SOD1(G93A) mouse model of amyotrophic lateral sclerosis and explore the possible mechanisms. METHODS: The SOD1(G93A) mice were treated by oral administration of BP (q.d., 400 mg/kg d) starting from 60 days of age and continuing until death. The rotarod test was performed to assess the disease onset. The expression levels of apoptosis-related proteins, inflammatory molecules, and autophagy-associated proteins were determined...
February 22, 2017: CNS Neuroscience & Therapeutics
https://www.readbyqxmd.com/read/28228632/physical-and-psychological-characteristics-of-the-community-dwelling-elderly-with-heart-disease
#12
Takeshi Kera, Hisashi Kawai, Hideyo Yoshida, Hirohiko Hirano, Motonaga Kojima, Yoshinori Fujiwara, Kazushige Ihara, Shuichi Obuchi
Objectives Although the survival rates of patients with heart diseases, such as myocardial infarction and heart failure, have increased, the incidence of heart disease in elderly individuals has also increased. We compared characteristics of the community-dwelling elderly with heart diseases (heart disease group) and without heart diseases (non-heart disease group).Methods A total of 758 elderly individuals participated in our survey ("Otassha-kensin") in 2014. The heart disease group (47 men, 28 women) and the non-heart disease group (263 men, 420 women) were selected from among these participants...
2017: [Nihon Kōshū Eisei Zasshi] Japanese Journal of Public Health
https://www.readbyqxmd.com/read/28228619/a-case-of-anti-3-hydroxy-3-methylglutaryl-coenzyme-a-reductase-antibody-positive-paraneoplastic-necrotizing-myopathy-associated-with-advanced-gastric-cancer-that-responded-to-intravenous-immunoglobulin-therapy
#13
Tomohisa Yamaguchi, Akiko Matsunaga, Masamichi Ikawa, Norimichi Shirafuji, Ichizo Nishino, Tadanori Hamano
A 49-year-old woman presented with progressive muscle weakness of the limbs and dysphagia. Her past and family medical history were unremarkable and she did not take statins or any other medications. Laboratory tests showed that serum levels of creatine kinase were elevated (13,565 IU/l) and anti-3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) antibodies were detected in the serum. Other autoantibodies to the nuclear (ANA), RNP, aminoacyl-tRNA synthetases (ARS), and signal recognition particle (SRP) were negative...
February 22, 2017: Rinshō Shinkeigaku, Clinical Neurology
https://www.readbyqxmd.com/read/28228296/morphometry-of-the-triangle-of-koch-and-position-of-the-coronary-sinus-opening-in-cadaveric-fetal-hearts
#14
Sharan Shanubhogue, Thuslima Mohamed, Nachiket Shankar
AIMS: The aim of the present study was to determine the variations in the position of the coronary sinus (CS) ostium in normal cadaveric fetal (28 weeks or more) hearts and to assess the impact that these variations had on the dimensions of the triangle of Koch (TK). METHODS: This cross-sectional analytical study was conducted on 28 fetal hearts. The dimensions and area of the TK were calculated by two methods, M1 (anatomical) and M2 (clinical). The position of the CS was defined with respect to the tendon of Todaro...
January 2017: Indian Heart Journal
https://www.readbyqxmd.com/read/28228100/influence-of-hooks-and-a-lag-screw-on-internal-fixation-plates-for-lateral-malleolar-fracture-a-biomechanical-and-ergonomic-study
#15
Rina Sakai, Masataka Uchino, Terumasa Yoneo, Yasuaki Ohtaki, Hiroaki Minehara, Terumasa Matsuura, Tsutomu Gomi, Masanobu Ujihira
BACKGROUND: For internal fixation of AO classification Type B lateral malleolar fracture, insertion of lag screws into the fracture plane and fixation with a one-third tubular plate as a neutralization plate are the standard treatment procedures. The one-third tubular plate is processed to a hook shape and hung on the distal end of the fibula. In this study, to compare the function of the hook and lag screws of a one-third tubular plate and LCP for osteosynthesis of lateral malleolar fracture, mechanical indices of internal fixation were compared among the one-third tubular plates with lag screws with and without the hook and a locking compression plate...
February 23, 2017: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/28227837/progressive-abduction-loading-therapy-targeting-flexion-synergy-to-regain-reaching-function-in-chronic-stroke-preliminary-results-from-an-rct
#16
Michael D Ellis, Carolina Carmona, Justin Drogos, Stuart Traxel, Julius P A Dewald, Michael D Ellis, Carolina Carmona, Justin Drogos, Stuart Traxel, Julius P A Dewald, Stuart Traxel, Michael D Ellis, Carolina Carmona, Julius P A Dewald, Justin Drogos
Reaching function is impaired following stroke due to abnormal coupling of shoulder abduction and elbow flexion. This phenomenon is commonly referred to as flexion synergy, loss of independent joint control, or impaired joint individuation. We have been successful in treating individuals with chronic stroke with moderate to severe motor impairments through the employment of targeted rehabilitation robotics and identified progressive abduction loading as a key element to the rehabilitation of reaching. Here we expand upon the investigation of progressive abduction loading therapy by testing two variants of the exercise in a larger sample and including a 3-month follow-up...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227768/measures-of-the-brain-functional-network-that-correlate-with-alzheimer-s-neuropsychological-test-scores-an-fmri-and-graph-analysis-study
#17
Soroosh Golbabaei, Amin Dadashi, Hamid Soltanian-Zadeh, Soroosh Golbabaei, Amin Dadashi, Hamid Soltanian-Zadeh, Soroosh Golbabaei, Amin Dadashi, Hamid Soltanian-Zadeh
Neural degeneration in Alzheimer's disease (AD) leads to structural topology deformation that in turn changes brain functionality. The main aim of the present study is to find the brain's functional connectivity network (FCN) correlates of Alzheimer's psychological test scores. To this end, the brain's FCN is extracted from the resting state functional magnetic resonance images (rs-fMRI) of healthy controls and patients with AD and represented as a graph. Then, network measures are calculated from the graphs...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227723/balance-quality-assessment-as-an-early-indicator-of-physical-frailty-in-older-people
#18
Aly Chkeir, Doha Safieddine, D Bera, M Collart, J L Novella, M Drame, David J Hewson, Jacques Duchene, Aly Chkeir, Doha Safieddine, D Bera, M Collart, J L Novella, M Drame, David J Hewson, Jacques Duchene, J L Novella, David J Hewson, Jacques Duchene, M Collart, Aly Chkeir, D Bera, M Drame, Doha Safieddine
Frailty is an increasingly common geriatric condition that results in an increased risk of adverse health outcomes such as falls. The most widely-used means of detecting frailty is the Fried phenotype, which includes several objective measures such as grip strength and gait velocity. One method of screening for falls is to measure balance, which can be done by a range of techniques including the assessment of the Centre of Pressure (CoP) during a balance assessment. The Balance Quality Tester (BQT) is a device based on a commercial bathroom scale that can evaluate balance quality...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227640/hardness-map-of-human-meta-tarsals-and-phalanges-of-toes
#19
Irfan Manarvi, Irfan Manarvi, Irfan Manarvi
Predicting location of fracture in human bones has been a keen area of research for the past few decades. A variety of tests for hardness, deformation and strain field measurement have been conducted in the past; but considered insufficient due to various limitations. Researchers therefore have proposed further studies due to inaccuracies in measurement methods, testing machines and experimental errors. Advancement and availability of hardware, measuring instrumentation and testing machines can now provide remedies to these limitations...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227303/age-related-neuromuscular-changes-in-semg-of-m-tibialis-anterior-using-higher-order-statistics-gaussianity-linearity-test
#20
Ariba Siddiqi, Sridhar P Arjunan, Dinesh K Kumar, Ariba Siddiqi, Sridhar P Arjunan, Dinesh K Kumar, Ariba Siddiqi, Dinesh K Kumar, Sridhar P Arjunan
Age-associated changes in the surface electromyogram (sEMG) of Tibialis Anterior (TA) muscle can be attributable to neuromuscular alterations that precede strength loss. We have used our sEMG model of the Tibialis Anterior to interpret the age-related changes and compared with the experimental sEMG. Eighteen young (20-30 years) and 18 older (60-85 years) performed isometric dorsiflexion at 6 different percentage levels of maximum voluntary contractions (MVC), and their sEMG from the TA muscle was recorded. Six different age-related changes in the neuromuscular system were simulated using the sEMG model at the same MVCs as the experiment...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
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