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https://www.readbyqxmd.com/read/28934138/inhibitory-effects-of-culinary-herbs-and-spices-on-the-growth-of-hca-7-colorectal-cancer-cells-and-their-cox-2-expression
#1
Andrius Jaksevicius, Mark Carew, Calli Mistry, Helmout Modjtahedi, Elizabeth I Opara
It is unclear if the anti-inflammatory properties of culinary herbs and spices (CHS) are linked to their ability to inhibit Colorectal cancer cell (CRC) growth. Furthermore, their therapeutic potential with regards to CRC is unknown. The aim of this study was to establish if the inhibition of HCA-7 CRC cell growth by a selection of culinary herbs and spices (CHS) is linked to the inhibition of the cells' cyclooxygenase-2 (COX-2 )expression, and to investigate their therapeutic potential. CHS inhibited the growth of Human colon adenocarcinoma-7 (HCA-7) cells; the order of potency was turmeric, bay leaf, ginger, sage, and rosemary; their combinations had a synergistic or additive effect on cell growth inhibition...
September 21, 2017: Nutrients
https://www.readbyqxmd.com/read/28933794/inhibitory-profiles-of-spices-against-free-and-protein-bound-heterocyclic-amines-of-roast-beef-patties-as-revealed-by-ultra-performance-liquid-chromatography-tandem-mass-spectrometry-and-principal-component-analysis
#2
Jing Chen, Zhiyong He, Fang Qin, Jie Chen, Dongsheng Cao, Fengxian Guo, Maomao Zeng
The effects of various levels of chili pepper, Sichuan pepper, and black pepper on the amounts of 17 heterocyclic amines (HAs) from seven categories of both free and protein-bound states in roast beef patties were assessed by ultra-performance liquid chromatography-tandem mass spectrometry combined with principal component analysis. Three groups of HA, including imidazopyridines (DMIP), imidazoquinoxalines (MeIQx and 4,8-MeIQx), and β-carbolines (norharman and harman), were detected and quantified in both their free and protein-bound states, whereas PhIP was detected only in its free state, and imidazoquinolines (IQ, IQ[4,5-b], and MeIQ), α-carbolines (AαC and MeAαC), and phenylpyridines (Phe-P-1) were detected only in their protein-bound states...
September 21, 2017: Food & Function
https://www.readbyqxmd.com/read/28930277/biological-activities-of-three-essential-oils-of-the-lamiaceae-family
#3
REVIEW
Gema Nieto
Herbs and spices have been used since ancient times to improve the sensory characteristics of food, to act as preservatives and for their nutritional and healthy properties. Herbs and spices are generally recognized as safe (GRAS) and are excellent substitutes for chemical additives. Essential oils are mixtures of volatile compounds obtained, mainly by steam distillation, from medicinal and aromatic plants. They are an alternative to synthetic additives for the food industry, and they have gained attention as potential sources for natural food preservatives due to the growing interest in the development of safe, effective, natural food preservation...
August 23, 2017: Medicines (Basel, Switzerland)
https://www.readbyqxmd.com/read/28930244/characterization-and-antioxidant-activity-of-volatile-constituents-from-different-parts-of-aframomum-danielli-hook-k-schum
#4
Emmanuel E Essien, Paul S Thomas, Kelly Oriakhi, Mohammad I Choudhary
Background:Aframomum danielli is used in ethno-medicine for the treatment of several ailments and as a traditional food spice. Methods: The hydro-distilled leaf, stem, seed, rhizome and pod volatile oils of A. danielli were subjected to gas chromatography-mass spectrometry (GC-MS) analysis. Free radical scavenging capacity of the volatile oils was determined using 2,2-diphenyl-1-picrylhydrazyl (DPPH) and ferric reducing antioxidant power (FRAP) assays. Results: Thirty-nine (39) volatile compounds were identified in the oils of A...
May 10, 2017: Medicines (Basel, Switzerland)
https://www.readbyqxmd.com/read/28930239/eryngium-foetidum-l-essential-oils-chemical-composition-and-antioxidant-capacity
#5
Paul S Thomas, Emmanuel E Essien, Samuel J Ntuk, Mohammad I Choudhary
Background:Eryngium foetidum essential oils from Nigeria were investigated for the first time in order to ascertain their potency as natural antioxidants. E. foetidum is an aromatic and medicinal herb used in ethno-medicine and as a traditional spice for foods. Methods: The hydro-distilled oils of E. foetidum were subjected to gas chromatography-mass spectrometry (GC-MS) analysis. Free radical scavenging capacity of the volatile oils was determined using 2, 2-diphenyl-1-picrylhydrazyl (DPPH) and ferric reducing antioxidant power (FRAP) assays...
April 28, 2017: Medicines (Basel, Switzerland)
https://www.readbyqxmd.com/read/28928401/metabolic-shift-in-sugars-and-amino-acids-regulates-sprouting-in-saffron-corm
#6
Jayram Bagri, Anupama Yadav, Khalid Anwar, Jeremy Dkhar, Sneh Lata Singla-Pareek, Ashwani Pareek
Saffron is one of the most expensive spices of the world. Since this spice is triploid and meiosis is unusual, it cannot reproduce sexually like other plants; rather, it is propagated vegetatively via an underground corm, which can withstand a long dry dormant period before sprouting. Thus, corms are indispensable to saffron propagation. To identify and analyse signature metabolites associated with the 'dormancy-sprouting' process, non-targeted GC-MS was performed at different stages of corm development. Comparative metabolite profiling reflected dissimilar profiles among the stages as portrayed by differential cluster patterns of metabolites in the PCA and PLS-DA analysis...
September 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28927012/fiber-patterns-in-young-adults-living-in-different-environments-usa-spain-and-tunisia-anthropometric-and-lifestyle-characteristics
#7
María José García-Meseguer, Amalia Delicado-Soria, Ramón Serrano-Urrea
Benefits of dietary fiber go beyond its effect on chronic diseases associated with development. Consequently, the pattern of fiber intake has been considered an indicator for diet quality. Young adults are especially vulnerable to a food environment that drives an increase in chronic diseases linked to economic development. The aim of this work was to characterize patterns of fiber intake among university students. A cross-sectional study was conducted on a sample of 730 students enrolled at the University of Castilla-La Mancha (Spain), the University of Carthage (Tunisia), and Florida International University (USA)...
September 18, 2017: Nutrients
https://www.readbyqxmd.com/read/28917744/differentiation-of-cumin-seeds-using-a-metal-oxide-based-gas-sensor-array-in-tandem-with-chemometric-tools
#8
Mahdi Ghasemi-Varnamkhasti, Zahra Safari Amiri, Mojtaba Tohidi, Majid Dowlati, Seyed Saeid Mohtasebi, Adenilton C Silva, David D S Fernandes, Mário C U Araujo
Cumin is a plant of the Apiaceae family (umbelliferae) which has been used since ancient times as a medicinal plant and as a spice. The difference in the percentage of aromatic compounds in cumin obtained from different locations has led to differentiation of some species of cumin from other species. The quality and price of cumin vary according to the specie and may be an incentive for the adulteration of high value samples with low quality cultivars. An electronic nose simulates the human olfactory sense by using an array of sensors to distinguish complex smells...
January 1, 2018: Talanta
https://www.readbyqxmd.com/read/28915468/spectral-and-computational-features-of-the-binding-between-riparins-and-human-serum-albumin
#9
Cintia Ramos Camargo, Ícaro Putinhon Caruso, Stanley Juan Chavez Gutierrez, Marcelo Andres Fossey, José Maria Barbosa Filho, Marinônio Lopes Cornélio
The green Brazilian bay leaf, a spice much prized in local cuisine (Aniba riparia, Lauraceae), contains chemical compounds presenting benzoyl-derivatives named riparins, which have anti-inflammatory, antimicrobial and anxiolytic properties. However, it is unclear what kind of interaction riparins perform with any molecular target. As a profitable target, human serum albumin (HSA) is one of the principal extracellular proteins, with an exceptional capacity to interact with several molecules, and it also plays a crucial role in the transport, distribution, and metabolism of a wide variety of endogenous and exogenous ligands...
September 8, 2017: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/28914764/antioxidant-activity-of-spices-and-their-impact-on-human-health-a-review
#10
REVIEW
Alexander Yashin, Yakov Yashin, Xiaoyan Xia, Boris Nemzer
Antioxidants are substances that prevent oxidation of other compounds or neutralize free radicals. Spices and herbs are rich sources of antioxidants. They have been used in food and beverages to enhance flavor, aroma and color. Due to their excellent antioxidant activity, spices and herbs have also been used to treat some diseases. In this review article, the chemical composition and antioxidant activity of spices and culinary herbs are presented. The content of flavonoids and total polyphenols in different spices and herbs are summarized...
September 15, 2017: Antioxidants (Basel, Switzerland)
https://www.readbyqxmd.com/read/28901261/spices-with-breast-cancer-chemopreventive-and-therapeutic-potentials-a-functional-foods-based-review
#11
Aliyu Muhammad, Mohammed Auwal Ibrahim, Ochuko Lucky Erukainure, Ibrahim Malami, Auwal Adamu
Cancer is a disease that affects a significant number of both rural and urban dwellers. Among the various types of cancer, breast cancer is one of the most common diagnosed cancers among females. Its menace can be curbed with locally consumed spices due to their multiple bioactive phytochemicals. This review focuses on the breast cancer chemopreventive and therapeutic potentials of locally consumed spices. The most commonly consumed spices with breast cancer chemopreventive and chemotherapeutic phytochemical include pepper, onions, ginger, garlic, curry and thyme containing many biologically active metabolites ranging from vitamins, fatty acids esters, polyphenols/phenolics, sulfur-containing compounds and anthraquinones with proven antioxidant, anti-inflammatory, immuno-modulatory, antitumor and anticancer properties against breast cancer/carcinogenesis...
September 12, 2017: Anti-cancer Agents in Medicinal Chemistry
https://www.readbyqxmd.com/read/28894619/immunological-reactivity-using-monoclonal-and-polyclonal-antibodies-of-autoimmune-thyroid-target-sites-with-dietary-proteins
#12
Datis Kharrazian, Martha Herbert, Aristo Vojdani
Many hypothyroid and autoimmune thyroid patients experience reactions with specific foods. Additionally, food interactions may play a role in a subset of individuals who have difficulty finding a suitable thyroid hormone dosage. Our study was designed to investigate the potential role of dietary protein immune reactivity with thyroid hormones and thyroid axis target sites. We identified immune reactivity between dietary proteins and target sites on the thyroid axis that includes thyroid hormones, thyroid receptors, enzymes, and transport proteins...
2017: Journal of Thyroid Research
https://www.readbyqxmd.com/read/28894509/effects-of-polyphenol-intake-on-metabolic-syndrome-current-evidences-from-human-trials
#13
REVIEW
Gemma Chiva-Blanch, Lina Badimon
Metabolic syndrome (MetS) is a cluster of cardiovascular risk factors which severely increases the risk of type II diabetes and cardiovascular disease. Several epidemiological studies have observed a negative association between polyphenol intake and MetS rates. Nevertheless, there are relatively small numbers of interventional studies evidencing this association. This review is focused on human interventional trials with polyphenols as polyphenol-rich foods and dietary patterns rich in polyphenols in patients with MetS...
2017: Oxidative Medicine and Cellular Longevity
https://www.readbyqxmd.com/read/28888545/next-generation-sequencing-for-the-investigation-of-an-outbreak-of-salmonella-schwarzengrund-in-nanjing-china
#14
Xuefei Du, Xiao Jiang, Yanhua Ye, Baofu Guo, Wei Wang, Jie Ding, Guoxiang Xie
INTRODUCTION: Salmonella Schwarzengrund is most frequently isolated from poultry meat and can cause human infections. S. Schwarzengrund was isolated from diarrheal patients in a food poisoning event in Nanjing, China. METHODS: Three strains isolated from patients were microbiologically confirmed as S. Schwarzengrund. Salmonella strains from spiced donkey meat were also confirmed as S. Schwarzengrund. Epidemiology investigation showed evidence of a correlation between the consumption of spiced donkey meat and those cases...
September 6, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28888208/prophetic-medicine-as-potential-functional-food-elements-in-the-intervention-of-cancer-a-review
#15
REVIEW
Bassem Y Sheikh, Md Moklesur Rahman Sarker, Muhamad Noor Alfarizal Kamarudin, Amin Ismail
Amounting scientific evidences have revealed the antitumor, antimetastatic, antiangiogenic, antiproliferative, chemopreventive and neo-adjuvant efficacy of Prophetic Medicine in various in vitro, in vivo and clinical cancer models. Prophetic Medicine includes plants, dietary materials or spices that were used as remedy recipes and nutrition by the great Prophet Mohammed (peace be upon him) to treat various ailments. Prophetic medicine is the total authentic Hadith narrated by the Prophet (PBUH) in relation to medicine, whether Qur'anic verses or honourable Prophetic Hadith...
September 6, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28884496/potential-role-of-curcumin-against-biofilm-producing-organisms-on-the-skin-a-review
#16
REVIEW
Alexandra R Vaughn, Kelly N Haas, Waqas Burney, Erich Andersen, Ashley K Clark, Robert Crawford, Raja K Sivamani
Turmeric root (Curcuma longa) is predominantly used as a spice, but has also long been known to possess antimicrobial, analgesic, antiinflammatory, and anticancer properties. One predominant group of active compounds in turmeric are curcuminoids, namely bright yellow-pigmented curcumin. While modern science has yet to fully investigate the therapeutic claims of turmeric and its derivatives, results have proven promising in decreasing pain and inflammation in arthritis, improving insulin sensitivity in diabetes, and even curing a variety of infections...
September 7, 2017: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/28874764/natural-%C3%A2-9-thc-and-synthetic-jwh-018-cannabinoids-induce-seizures-by-acting-through-the-cannabinoid-cb1-receptor
#17
Olga Malyshevskaya, Kosuke Aritake, Mahesh K Kaushik, Nahoko Uchiyama, Yoan Cherasse, Ruri Kikura-Hanajiri, Yoshihiro Urade
Natural cannabinoids and their synthetic substitutes are the most widely used recreational drugs. Numerous clinical cases describe acute toxic symptoms and neurological consequences following inhalation of the mixture of synthetic cannabinoids known as "Spice." Here we report that an intraperitoneal administration of the natural cannabinoid Δ(9)-tetrahydrocannabinol (10 mg/kg), one of the main constituent of marijuana, or the synthetic cannabinoid JWH-018 (2.5 mg/kg) triggered electrographic seizures in mice, recorded by electroencephalography and videography...
September 5, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28873765/greek-pdo-saffron-authentication-studies-using-species-specific-molecular-markers
#18
I Bosmali, S A Ordoudi, M Z Tsimidou, P Madesis
Saffron, the spice produced from the red stigmas of the flower of Crocus sativus L. is a frequent target of fraud and mislabeling practices that cannot be fully traced using the ISO 3632 trade standard specifications and test methods. A molecular approach is proposed herein as a promising branding strategy for the authentication of highly esteemed saffron brands such as the Greek Protected Designation of Origin (PDO) "Krokos Kozanis". Specific ISSR (inter-simple sequence repeat) markers were used to assess for the first time, the within species variability of several populations of C...
October 2017: Food Research International
https://www.readbyqxmd.com/read/28873536/development-and-validation-of-hplc-method-for-the-determination-of-ferrocyanide-ion-in-food-grade-salts
#19
Ho Soo Lim, Ju Young Hwang, EunA Choi, Gunyoung Lee, Sang Sun Yoon, MeeKyung Kim
A rapid, simple, and reliable HPLC method was developed and validated to determine the presence of ferrocyanide ions (FeCNs) in food grade salts. An analytical column coupled with a guard column and mobile phase comprised of sodium perchlorate and sodium hydroxide (NaOH) were employed at a detection wavelength of 221nm. Samples were dissolved in 0.02M NaOH solution and filtered. For processed salts including herbs and spices, a C18 cartridge was applied to minimize interference from salt matrices. The method validation was based on linearity, accuracy (recovery), precision, LOD, LOQ, and measurement uncertainty...
January 15, 2018: Food Chemistry
https://www.readbyqxmd.com/read/28870897/phosphoproteomic-analysis-identifies-signaling-pathways-regulated-by-curcumin-in-human-colon-cancer-cells
#20
Tatsuhiro Sato, Yutaka Higuchi, Yoshio Shibagaki, Seisuke Hattori
BACKGROUND: Curcumin, a major polyphenol of the spice turmeric, acts as a potent chemopreventive and chemotherapeutic agent in several cancer types, including colon cancer. Although various proteins have been shown to be affected by curcumin, how curcumin exerts its anticancer activity is not fully understood. MATERIALS AND METHODS: Phosphoproteomic analyses were performed using SW480 and SW620 human colon cancer cells to identify curcumin-affected signaling pathways...
September 2017: Anticancer Research
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