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https://www.readbyqxmd.com/read/28432760/determination-of-ochratoxin-a-in-black-and-white-pepper-nutmeg-spice-mix-cocoa-and-drinking-chocolate-by-high-performance-liquid-chromatography-coupled-with-fluorescence-detection-collaborative-study
#1
Elena Cubero-Leon, Katrien Bouten, Hamide Senyuva, Joerg Stroka
A method validation study for the determination of ochratoxin A in black and white pepper (Piper spp.), nutmeg (Myristica fragrans), spice mix (blend of ginger, turmeric, pepper, nutmeg, and chili), cocoa powder, and drinking chocolate was conducted according to the International Harmonized Protocol of the International Union of Pure and Applied Chemistry. The method is based on the extraction of samples with aqueous methanol, followed by a cleanup of the extract with an immunoaffinity column. The determination is carried out by reversed-phase LC coupled with a fluorescence detector...
April 22, 2017: Journal of AOAC International
https://www.readbyqxmd.com/read/28427103/saffron-flower-extract-promotes-scratch-wound-closure-of-keratinocytes-and-enhances-vegf-production
#2
Sheela Verjee, Eliane Garo, Sarah Pelaez, Orlando Fertig, Matthias Hamburger, Veronika Butterweck
During saffron (Crocus sativus) spice production, large amounts of floral biowaste are generated. It was the aim of this study to develop a value-added product from saffron floral biowaste to be used as a natural cosmetic ingredient. HPLC-PDA-MS analysis of saffron flower extracts revealed the presence of flavonols with the highest amounts in the acetone extract. Kaempferol-3-O-sophoroside was identified as the main flavonoid in the acetone extract (saffron flower acetone extract). Saffron flower acetone extract and kaempferol-3-O-sophoroside were tested in HaCaT cells for potential effects on cell migration, proliferation, and for anti-inflammatory properties...
April 20, 2017: Planta Medica
https://www.readbyqxmd.com/read/28421410/antiparasitic-sesquiterpenes-from-the-cameroonian-spice-scleria-striatinux-and-preliminary-in-vitro-and-in-silico-dmpk-assessment
#3
Kennedy D Nyongbela, Fidele Ntie-Kang, Thomas R Hoye, Simon M N Efange
The antiparasitic activity and preliminary in vitro and in silico drug metabolism and pharmacokinetic (DMPK) assessment of six isomeric sesquiterpenes (1-6), isolated from the Cameroonian spice Scleria striatinux De Wild (Cyperaceae) is reported. The study was prompted by the observation that two of the compounds (1 and 2) exhibited varying levels of antiparasitic activity on Plasmodium falciparum, Trypanosoma brucei rhodesiense, Trypanosoma cruzi and Leishmania donovani. The in silico method employed a total of 46 descriptors, calculated using Schrödinger QikProp software...
April 18, 2017: Natural Products and Bioprospecting
https://www.readbyqxmd.com/read/28417091/biological-activities-of-curcuminoids-other-biomolecules-from-turmeric-and-their-derivatives-a-review
#4
REVIEW
Augustine Amalraj, Anitha Pius, Sreerag Gopi, Sreeraj Gopi
In recent years, several drugs have been developed deriving from traditional products and current drug research is actively investigating the possible therapeutic roles of many Ayruvedic and Traditional Indian medicinal therapies. Among those being investigated is Turmeric. Its most important active ingredient is curcuminoids. Curcuminoids are phenolic compounds commonly used as a spice, pigment and additive also utilized as a therapeutic agent used in several foods. Comprehensive research over the last century has revealed several important functions of curcuminoids...
April 2017: Journal of Traditional and Complementary Medicine
https://www.readbyqxmd.com/read/28416856/microbial-analysis-of-map-pot-stewed-duck-wings-under-different-conditions-during-15%C3%A2-%C3%A2-c-storage
#5
Keping Ye, Jian Jiang, Yuefan Wang, Yifan Hou, Mei Liu, Jia Liu, Chengxiang Guo
This study was to investigate the changes of microbial community and counts of MAP pot-stewed duck wing (PSDW) under different packaging films and spices ratio during 15 °C storage, using the traditional bacterial cultivation and PCR-DGGE. Results of microbial counting showed that the shelf-life of PDSW during 15 °C storage for recommendation was within six days, and the packaging films and spices ratio didn't affect the change of microbial numbers in PSDW during storage. PCR-DGGE analysis revealed that Staphylococcus equorum, Weissella sp...
April 2017: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/28412917/is-there-a-teratogenicity-risk-associated-with-cannabis-and-synthetic-cannabimimetics-spice-intake
#6
Laura Orsolini, Duccio Papanti, John Corkery, Maria Antonietta De Luca, Cristina Cadoni, Gaetano Di Chiara, Fabrizio Schifano
BACKGROUND: Substance use, including cannabis, has been documented amongst women both in the pre-conception period and during pregnancy, particularly during the 1st trimester, which is clearly the most critical period in the organogenesis. The recent emergence on the drug market of synthetic cannabimimetics/SC ('spice') may represent a new challenge for clinicians. OBJECTIVE: A literature overview on the teratogenicity profile of both cannabis and synthetic cannabimimetics was here carried out...
April 13, 2017: CNS & Neurological Disorders Drug Targets
https://www.readbyqxmd.com/read/28411462/flavone-polyphenols-dominate-in-thymus-schimperi-ronniger-lc-esi-ms-ms-characterization-and-study-of-anti-proliferative-effects-of-plant-extract-on-ags-and-hepg2-cancer-cells
#7
Kebede Taye Desta, Gon Sup Kim, A M Abd El-Aty, Suchismita Raha, Man-Bae Kim, Ji Hoon Jeong, Mohamad Warda, Ahmet Hacımüftüoğlu, Ho-Chul Shin, Jae-Han Shim, Sung Chul Shin
Thymus schimperi is a highly localized and a rare plant endemic to Ethiopia. An optimized and validated high-performance liquid chromatography-electrospray ionization-tandem mass spectrometry (HPLC-ESI-MS/MS) method was applied to characterize 23 polyphenolic compounds found in ethyl acetate extracts of the plant. From those, flavones dominated and luteolin was the major component contributing 21.83% of the total composition (or 46.05±0.59g/kg of fresh sample weight). Validation data showed a determination coefficient (R(2))≥0...
March 31, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/28410669/curcumin-and-linseed-oil-co-delivered-in-phospholipid-nanoemulsions-enhances-the-levels-of-docosahexaenoic-acid-in-serum-and-tissue-lipids-of-rats
#8
D Sugasini, B R Lokesh
Docosahexaenoic acid (DHA) is an important long chain omega-3 polyunsaturated fatty acid (PUFA) primarily found in marine fishes. The diets of vegetarian population do not contain preformed DHA, but they can derive it from shorter chain α-linolenic acid (ALA) found in plant oils. However, the conversion efficiency of ALA to DHA is minimal in human adults. This may cause insufficiency of DHA in the vegetarian population. Curcumin, diferuloyl methane found in the spice turmeric, has the potential to increase the formation of DHA from ALA by activating the enzymes FADS2 and elongase 2...
April 2017: Prostaglandins, Leukotrienes, and Essential Fatty Acids
https://www.readbyqxmd.com/read/28407236/processes-to-preserve-spice-and-herb-quality-and-sensory-integrity-during-pathogen-inactivation
#9
Susan E Duncan, Kayla Moberg, Kemia N Amin, Melissa Wright, Jordan J Newkirk, Monica A Ponder, Gary R Acuff, James S Dickson
Selected processing methods, demonstrated to be effective at reducing Salmonella, were assessed to determine if spice and herb quality was affected. Black peppercorn, cumin seed, oregano, and onion powder were irradiated to a target dose of 8 kGy. Two additional processes were examined for whole black peppercorns and cumin seeds: ethylene oxide (EtO) fumigation and vacuum assisted-steam (82.22 °C, 7.5 psia). Treated and untreated spices/herbs were compared (visual, odor) using sensory similarity testing protocols (α = 0...
April 13, 2017: Journal of Food Science
https://www.readbyqxmd.com/read/28406728/clinical-evaluation-of-a-polyherbal-nutritional-supplement-in-dyslipidemic-volunteers
#10
Subramanian Suganya, Subapriya Natarajan, Duraipandian Chamundeeswari, Anand Anbarasu, Kunissery A Balasubramanian, Lynn C Schneider, Balaji Nandagopal
Ten important plant parts routinely used in South Indian ethnic food preparation as spices and condiments were investigated for their potential antidyslipidemic properties. The aim of the study was to characterize the biochemical properties of the polyherbal formulation (nutritional supplement) and evaluate its use to control dyslipidemia in patients. Phytochemical evaluation, in vitro α-amylase inhibitory assay, and high performance thin layer chromatography (HPTLC) fingerprinting were carried out with alcoholic extracts of all 10 individual plants and with the nutritional supplement...
April 13, 2017: Journal of Dietary Supplements
https://www.readbyqxmd.com/read/28404858/small-spice-for-big-wounds-can-curcumin-close-the-gap
#11
Hadar Lev-Tov
Nanoformulation of curcumin may be the key to unlocking its wound healing potential.
April 12, 2017: Science Translational Medicine
https://www.readbyqxmd.com/read/28398625/novel-creation-of-a-rum-flavor-lexicon-through-the-use-of-web-based-material
#12
Chelsea M Ickes, Soo-Yeun Lee, Keith R Cadwallader
Flavor lexicons help both manufacturers and consumers communicate the intricacies of flavor nuances they experience within a product. Lexicon development typically requires the use of a trained sensory panel to evaluate a representative sample set of the product category to generate terms that describe certain product attributes. In the case of rum, there is considerable variation in terms of style, flavor characteristics, and the sheer number of rums produced making it difficult to create a lexicon in this manner...
April 11, 2017: Journal of Food Science
https://www.readbyqxmd.com/read/28397254/modern-analytical-methods-for-the-detection-of-food-fraud-and-adulteration-by-food-category
#13
REVIEW
Eunyoung Hong, Sang Yoo Lee, Jae Yun Jeong, Jung Min Park, Byung Hee Kim, Kisung Kwon, Hyang Sook Chun
This review provides current information on the analytical methods used to identify food adulteration in the six most adulterated food categories: animal origin and seafood, oils and fats, beverages, spices and sweet foods (e.g. honey), grain-based food, and others (organic food and dietary supplements). The analytical techniques, both conventional and emerging, used to identify adulteration in these six food categories involve sensory, physicochemical, DNA-based, chromatographic, and spectroscopic methods, and have been combined with chemometrics, making these techniques more convenient and effective for the analysis of a broad variety of food products...
April 10, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28394634/ozone-in-the-food-industry-principles-of-ozone-treatment-mechanisms-of-action-and-applications-an-overview
#14
Agnieszka Joanna Brodowska, Agnieszka Nowak, Krzysztof Śmigielski
The food contamination issue requires continuous control of food at each step of the production process. High quality and safety of products are equally important factors in the food industry. They may be achieved with several, more or less technologically advanced methodologies. In this work, we review the role, contribution, importance, and impact of ozone as a decontaminating agent used to control and eliminate the presence of microorganisms in food products as well as to extend their shelf-life and remove undesirable odors...
April 10, 2017: Critical Reviews in Food Science and Nutrition
https://www.readbyqxmd.com/read/28394618/potential-eye-drop-based-on-a-calix-4-arene-nanoassembly-for-curcumin-delivery-enhanced-drug-solubility-stability-and-anti-inflammatory-effect
#15
Giuseppe Granata, Irene Paterniti, Corrada Geraci, Francesca Cunsolo, Emanuela Esposito, Marika Cordaro, Anna Rita Blanco, Salvatore Cuzzocrea, Grazia M L Consoli
Curcumin is an Indian spice with a wide spectrum of biological and pharmacological activities but poor aqueous solubility, rapid degradation, and low bioavailability that affect medical benefits. To overcome these limits in ophthalmic application, curcumin was entrapped in a polycationic calix[4]arene-based nanoaggregate by a simple and reproducible method. The calix[4]arene-curcumin supramolecular assembly (Calix-Cur) appeared as a clear colloidal solution consisting in micellar nanoaggregates with size, polydispersity index, surface potential, and drug loading percentage meeting the requirements for an ocular drug delivery system...
April 10, 2017: Molecular Pharmaceutics
https://www.readbyqxmd.com/read/28378160/the-dynamic-microbiota-profile-during-pepper-piper-nigrum-l-peeling-by-solid-state-fermentation
#16
Qisong Hu, Jiachao Zhang, Chuanbiao Xu, Congfa Li, Sixin Liu
White pepper (Piper nigrum L.), a well-known spice, is the main pepper processing product in Hainan province, China. The solid-state method of fermentation can peel pepper in a highly efficient manner and yield high-quality white pepper. In the present study, we used next-generation sequencing to reveal the dynamic changes in the microbiota during pepper peeling by solid-state fermentation. The results suggested that the inoculated Aspergillus niger was dominant throughout the fermentation stage, with its strains constituting more than 95% of the fungi present; thus, the fungal community structure was relatively stable...
April 4, 2017: Current Microbiology
https://www.readbyqxmd.com/read/28372725/analysis-of-volatile-compounds-by-open-air-ionization-mass-spectrometry
#17
Anil Kumar Meher, Yu-Chie Chen
This study demonstrates a simple method for rapid and in situ identification of volatile and endogenous compounds in culinary spice samples through mass spectrometry (MS). This method only requires a holder for solid spice sample (2-3 mm) that is placed close to a mass spectrometer inlet, which is applied with a high voltage. Volatile species responsible for the aroma of the spice samples can be readily detected by the mass spectrometer. Sample pretreatment is not required prior to MS analysis, and no solvent was used during MS analysis...
May 8, 2017: Analytica Chimica Acta
https://www.readbyqxmd.com/read/28369918/immunostimulatory-effect-of-aqueous-extract-of-coriandrum-sativum-l-seed-on-macrophages
#18
Momoko Ishida, Kosuke Nishi, Nanami Kunihiro, Hiroyuki Onda, Sogo Nishimoto, Takuya Sugahara
BACKGROUND: Coriandrum sativum L. seed is generally used as a spice and crude drug. Although many functions of the various components in C. sativum L. seed have been reported, the immunostimulatory effect of water-soluble components in C. sativum L. seed has not been studied. In this study, we focused on the immunostimulatory effect of C. sativum L. seed aqueous extract (CAE) on macrophages as a novel health function of C. sativum L. seed components. RESULTS: CAE significantly enhanced the production of tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6) in both RAW264...
April 2, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28369196/functional-genomics-of-apocarotenoids-in-saffron-insights-from-chemistry-molecular-biology-and-therapeutic-applications
#19
Manoj K Dhar, Munish Sharma, Archana Bhat, Nikhil K Chrungoo, Sanjana Kaul
Saffron is considered to be the costliest spice of the world. It has been regarded as highly valued medicinal plant in Ayurveda to treat various ailments. Over the past few years, considerable interest has developed in saffron because of its anticancer, antimutagenic, antioxidant and immunomodulatory properties. Saffron's colour, bitter taste and aroma are its three main and peculiar characteristics, which are conferred by three chemicals namely: crocin, picrocrocin and safranal, respectively. The present review focuses on recent research/progress made in saffron in the area of functional genomics and highlights the potential of several genes and transcription factors involved in carotenoid/apocarotenoid pathway and responsible for flavour and aroma of saffron...
March 28, 2017: Briefings in Functional Genomics
https://www.readbyqxmd.com/read/28368215/effects-of-lipid-formulations-on-clove-extract-spray-dried-powders-comparison-of-physicochemical-properties-storage-stability-and-in-vitro-intestinal-permeation
#20
Diego F Cortes-Rojas, Claudia R F Souza, Mong-Jen Chen, Guenther Hochhaus, Wanderley P Oliveira
Clove is an aromatic plant spice with potent antioxidant and anti-inflammatory activity. Eugenol is the main compound which contributes to such medicinal and nutritional benefits. To date, the formulation of unstable, volatile, and poorly water soluble compounds remains a challenging task. Lipid formulations can be used to improve physicochemical and biopharmaceutical properties of poorly soluble compounds. The aim of the present study is to investigate the effects of lipids such as Gelucire and Compritol on physicochemical properties, stability and in vitro intestinal permeation of spray dried powdered formulations loaded with clove's bioactive compounds...
April 3, 2017: Pharmaceutical Development and Technology
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