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N A Al-Eesa, A Johal, R G Hill, F S L Wong
OBJECTIVES: Dental materials that can form apatite offer the potential to not only prevent demineralisation but enhance remineralisation of the enamel. The objective of this study was to investigate the ability of a novel BAG-resin adhesive to form apatite in 3 immersion media. METHODS: A novel fluoride containing BAG-resin adhesive described previously, with 80% by weight filler load, was used to fabricate 90 disks. Each disk was immersed in 10ml of either tris buffer (TB), or artificial saliva at pH=7 (AS7) or pH=4 (AS4)...
May 17, 2018: Dental Materials: Official Publication of the Academy of Dental Materials
R Muthupradeepa, M Sivakumar, R Subadevi, V Suryanarayanan, Wei-Ren Liu
The present study emphases on the effect of toting of TiO2 filler on the electrochemical enactment of polymer electrolyte containing PVdF-co-HFP(30) + SEt3TFSI(10) + EC/PC(60) + TiO2(x) wt% (Poly (vinylidene fluoride-co-hexafluoropropylene + Triethylsulfoniumbis(trifluoromethylsulfonyl)imide + Ethylene carbonate/Propylene carbonate (1:1 ratio) + Titanium dioxide) for lithium battery applications. Composite electrolytes with different weight percentages of TiO2 were prepared and characterized by different surface analytical, thermal and electrochemical techniques...
January 1, 2018: Journal of Nanoscience and Nanotechnology
Jiwei Li, Jianwei Ma, Shaojuan Chen, Yudong Huang, Jinmei He
The large-scale applications of lysozyme in the pharmaceutical industry and food industry require more efficient and cost-effective techniques for its separation/purification. In the present study, graphene oxide (GO) was encapsulated into environmentally benign sodium alginate (SA) to prepare a Ca2+ crosslinked alginate/graphene oxide composite gel beads (Ca-SA/GO) which were then used to adsorb lysozyme from aqueous solutions. Compared with pure Ca2+ crosslinked alginate gel beads (Ca-SA), the as-prepared Ca-SA/GO has a lower swelling degree, an improved gel stability in salt solutions, and a higher mechanical performance...
August 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
Mark W Ashton, G Ian Taylor, Russell J Corlett
BACKGROUND: Most target areas for facial volumization procedures relate to the anatomical location of the facial or ophthalmic artery. Occasionally, inadvertent injection of hyaluronic acid (HA) filler into the arterial circulation occurs, and unrecognised, is irreparably associated with disastrous vascular complications.Of note, the site of complications, irrespective of the injection site, is similar, and falls into only 5 areas of the face, all within the functional angiosome of the facial or ophthalmic artery...
March 15, 2018: Plastic and Reconstructive Surgery
Priya Uppuluri, Lin Lin, Abdullah Alqarihi, Guanpingsheng Luo, Eman G Youssef, Sondus Alkhazraji, Nannette Y Yount, Belal A Ibrahim, Michael Anthony Bolaris, John E Edwards, Marc Swidergall, Scott G Filler, Michael R Yeaman, Ashraf S Ibrahim
Different pathogens share similar medical settings and rely on similar virulence strategies to cause infections. We have previously applied 3-D computational modeling and bioinformatics to discover novel antigens that target more than one human pathogen. Active and passive immunization with the recombinant N-terminus of Candida albicans Hyr1 (rHyr1p-N) protect mice against lethal candidemia. Here we determine that Hyr1p shares homology with cell surface proteins of the multidrug resistant Gram negative bacterium, Acinetobacter baumannii including hemagglutinin (FhaB) and outer membrane protein A (OmpA)...
May 10, 2018: PLoS Pathogens
Anja Forche, Gareth Cromie, Aleeza C Gerstein, Norma V Solis, Tippapha Pisithkul, Waracharee Srifa, Eric Jeffery, Darren Abbey, Scott G Filler, Aimée M Dudley, Judith Berman
In vitro studies suggest that stress may generate random standing variation, and that different cellular and ploidy states may evolve more rapidly under stress. Yet this idea has not been tested with pathogenic fungi growing within their host niche in vivo Here, we analyzed the generation of both genotypic and phenotypic diversity during exposure of Candida albicans to the mouse oral cavity. Ploidy, aneuploidy, loss of heterozygosity (LOH) and recombination were determined using flow cytometry and ddRADseq...
May 3, 2018: Genetics
Qiting Huang, Shuheng Huang, Xiaoxu Liang, Wei Qin, Fang Liu, Zhengmei Lin, Jingwei He
STATEMENT OF PROBLEM: The use of composite resin to restore teeth has increased substantially during the last decades. However, secondary caries and the fracture of restorations are the leading reasons for clinical restoration failure. Mechanically strong composite resins with caries-inhibition capabilities are needed. Although antibacterial dimethacrylate quaternary ammonium monomers have been synthesized, composite resin containing dimethacrylate quaternary ammonium monomers and glass fillers has rarely been reported...
April 30, 2018: Journal of Prosthetic Dentistry
Yohei Inaba, Shigehisa Uchiyama, Naoki Kunugita
BACKGROUND: The ammonia contained in tobacco fillers and mainstream and sidestream cigarette smoke accelerates nicotine dependence in cigarette smokers. Ammonia has been included in the non-exhaustive priority list of 39 tobacco components and emissions of cigarette published by the World Health Organization (WHO) Study Group on Tobacco Product Regulation. The development of a simple ammonia detection method will contribute to the establishment of tobacco product regulation under tobacco control policies and allow surveys to be conducted, even by laboratories with small research budgets...
April 27, 2018: Environmental Health and Preventive Medicine
Lidan Fan, Mengyue Wang, Zhen Zhang, Gang Qin, Xiaoyi Hu, Qiang Chen
Natural bamboo charcoal (BC) powder has been developed as a novel filler in order to further improve performances of the polyvinyl alcohol (PVA)-based alkaline solid polymer electrolyte (ASPE) by solution casting method. X-ray diffraction patterns of composite polymer electrolyte with BC revealed the decrease in the degree of crystallinity with increasing content of BC. Scanning electron microscopy images showed pores on a micrometer scale (average diameter about 2 μm) distributed inside and on the surface of the membranes, indicating a three-dimension network formed in the polymer framework...
April 26, 2018: Materials
Hang Wei, Julie E Boland, Zhenguang G Cai, Fang Yuan, Min Wang
We report 2 self-paced reading experiments investigating the longevity of structural priming effects in comprehending reduced relative clauses among adult Chinese-speaking learners of English. Experiment 1 showed that structural priming occurred both when prime and target sentences were immediately adjacent and when they were separated by 1 or 2 filler sentences of unrelated structures. Moreover, the magnitude of the priming effect held constant across different lag conditions. Experiment 2 replicated the persistent priming effect and ruled out the possibility that the effect was due to verb repetition priming...
April 26, 2018: Journal of Experimental Psychology. Learning, Memory, and Cognition
John E Edwards, Michael M Schwartz, Clint S Schmidt, Jack D Sobel, Paul Nyirjesy, Florian Schodel, Erica Marchus, Mary Lizakowski, Elizabeth A DeMontigny, Jesse Hoeg, Tuomas Holmberg, M Timothy Cooke, Keila Hoover, Lance Edwards, Mark Jacobs, Steven Sussman, Michael Augenbraun, Michael Drusano, Michael R Yeaman, Ashraf S Ibrahim, Scott G Filler, John P Hennessey
Background: Recurrent vulvovaginal candidiasis (RVVC) is a problematic form of mucosal Candida infection, characterized by repeated episodes per year. Candida albicans is the most common cause of RVVC. Currently, there are no immunotherapeutic treatments for RVVC. Methods: This exploratory randomized, double-blind, placebo-controlled trial evaluated an immunotherapeutic vaccine (NDV-3A) containing a recombinant C. albicans adhesin/invasin protein for prevention of RVVC...
April 25, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Sandra Pina, Rita Rebelo, Vitor Manuel Correlo, J Miguel Oliveira, Rui L Reis
Considerable advances in tissue engineering and regeneration have been accomplished over the last decade. Bioceramics have been developed to repair, reconstruct, and substitute diseased parts of the body and to promote tissue healing as an alternative to metallic implants. Applications embrace hip, knee, and ligament repair and replacement, maxillofacial reconstruction and augmentation, spinal fusion, bone filler, and repair of periodontal diseases. Bioceramics are well-known for their superior wear resistance, high stiffness, resistance to oxidation, and low coefficient of friction...
2018: Advances in Experimental Medicine and Biology
Peter Frederik Horstmann, Werner Herbert Hettwer, Michael Mørk Petersen
After surgical bone tumor removal, filling of the bone defect is frequently performed using a bone graft or bone graft substitute. During follow-up, precise quantification of changes in bone mineral density, within the treated bone defect, is very difficult using conventional X-ray examinations. The objectives of this study were to characterize the pattern of resorption/biodegradation of a composite calcium sulfate/hydroxyapatite bone graft substitute and to quantify the bone defect healing with repeated dual-energy X-ray absorptiometry (DXA) measurements...
March 23, 2018: Journal of Clinical Densitometry
Ksenia I Lukanina, Timofei E Grigoriev, Sergey V Krasheninnikov, Vissarion G Mamagulashvilli, Roman A Kamyshinsky, Sergey N Chvalun
A novel high-tech composite biomimetic matrixes for a wide range of medical purposes were prepared. The structure of scaffolds was inspired by the architecture of native decellularized tissue: material consists of a sponge and fibrous components of different spatial geometry based on cellulose acetate with collagen or chitosan filler. The fibrous component was prepared by electrospinning, the sponge - freeze-drying technique. The influence of main technological parameters, such as freeze mode, polymer type and concentration, etc...
July 1, 2018: Carbohydrate Polymers
Carine Tais Welter Meereis, Eliseu Aldrighi Münchow, Wellington Luiz de Oliveira da Rosa, Adriana Fernandes da Silva, Evandro Piva
PURPOSE: A systematic review was conducted to determine whether there were composition strategies available to reduce and control polymerization shrinkage stress development in resin-based restorative dental materials. DATA SOURCES: This report was reported in accordance with the PRISMA Statement. Two reviewers performed a literature search up to December 2016, without restriction of the year of publication, in seven databases: PubMed, Web of Science, Scopus, SciELO, LILACS, IBECS, and BBO...
March 23, 2018: Journal of the Mechanical Behavior of Biomedical Materials
Claudia Ursino, Roberto Castro-Muñoz, Enrico Drioli, Lassaad Gzara, Mohammad H Albeirutty, Alberto Figoli
The use of membrane-based technologies has been applied for water treatment applications; however, the limitations of conventional polymeric membranes have led to the addition of inorganic fillers to enhance their performance. In recent years, nanocomposite membranes have greatly attracted the attention of scientists for water treatment applications such as wastewater treatment, water purification, removal of microorganisms, chemical compounds, heavy metals, etc. The incorporation of different nanofillers, such as carbon nanotubes, zinc oxide, graphene oxide, silver and copper nanoparticles, titanium dioxide, 2D materials, and some other novel nano-scale materials into polymeric membranes have provided great advances, e...
April 3, 2018: Membranes
Kecheng Guan, Feng Liang, Haipeng Zhu, Jing Zhao, Wanqin Jin
Two-dimensional graphene oxide (GO) in hybrid membranes provides fast water transfer across its surface due to the abundant oxygenated functional groups affording water sorption and the hydrophobic basal plane to create fast transporting pathways. To establish more compatible and efficient interactions for GO and sodium alginate (SA) polymer chains, cations sourced from lignin-cation are employed to decorate GO (labelled as CG) nanosheets via cation-π and π-π interactions providing more interactive sites to confer synergetic benefits with polymer matrix...
April 2, 2018: ACS Applied Materials & Interfaces
Norma V Solis, Yang-Nim Park, Marc Swidergall, Karla J Daniels, Scott G Filler, David R Soll
The capacity of C. albicans to switch reversibly between the white phenotype and the opaque phenotype is required for the fungus to mate. It also influences virulence during hematogenously disseminated candidiasis. We investigated the roles of the mating type loci ( MTL ) and white-opaque switching in the capacity of C. albicans to mate in the oropharynx and cause oropharyngeal candidiasis (OPC). When immunosuppressed mice were orally infected with opaque, mating competent opaque a/a and α/α cells either alone or mixed with white cells, no detectable mating occurred, indicating that the mating frequency was less than 1...
March 26, 2018: Infection and Immunity
Pere R Ramel, Alejandro G Marangoni
In this study, we show that the replacement of milk fat with canola oil in a model caseinate-based imitation cheese product to increase its nutritional value can be done by treating processed cheese as a particle filled gel network. Using microscopy, model imitation cheese products with different lipid phases were found to have similar microstructures where fat or oil appears as inert particle fillers in a continuous protein network. Using a texture profile analyzer, we show that the textural properties of model imitation cheese are dependent on the material properties of the inert filler...
May 2018: Food Research International
M G Raucci, C Demitri, A Soriente, I Fasolino, A Sannino, L Ambrosio
This study reports on the development of a scaffold with a gradient of bioactive solid signal embedded in the biodegradable polymer matrix by combining a sol-gel approach and freeze-drying technology. The chemical approach based on the sol-gel transition of calcium phosphates ensures the particles dispersion into the gelatin matrix and a direct control of interaction among COOHgelatin /Ca2+ ions. Morphological analysis demonstrated that on the basis of the amount of inorganic component and by using specific process conditions, it is possible to control the spatial distribution of nanoparticles around the gelatin helix...
March 25, 2018: Journal of Biomedical Materials Research. Part A
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