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https://www.readbyqxmd.com/read/28550146/does-painless-rectal-bleeding-equate-to-a-colonic-polyp
#1
Alison Morag Campbell, Ian Sugarman
BACKGROUND: It is often stated that if a patient presents with 'painless rectal bleeding' then a rectal polyp is the probable diagnosis. The aim of this study is to review our experience of children undergoing endoscopy to assess if the above statement is correct. METHODS: The senior author keeps a prospective database of every child undergoing flexible sigmoidoscopy or colonoscopy. As part of this database, the symptoms and signs that the patient presents with, specifically abdominal pain, diarrhoea, mucous per rectum and rectal bleeding, are recorded...
May 26, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28549783/irinotecan-temozolomide-with-temsirolimus-or-dinutuximab-in-children-with-refractory-or-relapsed-neuroblastoma-cog-anbl1221-an-open-label-randomised-phase-2-trial
#2
Rajen Mody, Arlene Naranjo, Collin Van Ryn, Alice L Yu, Wendy B London, Barry L Shulkin, Marguerite T Parisi, Sabah-E-Noor Servaes, Mitchell B Diccianni, Paul M Sondel, Julia G Bender, John M Maris, Julie R Park, Rochelle Bagatell
BACKGROUND: Outcomes for children with relapsed and refractory neuroblastoma are dismal. The combination of irinotecan and temozolomide has activity in these patients, and its acceptable toxicity profile makes it an excellent backbone for study of new agents. We aimed to test the addition of temsirolimus or dinutuximab to irinotecan-temozolomide in patients with relapsed or refractory neuroblastoma. METHODS: For this open-label, randomised, phase 2 selection design trial of the Children's Oncology Group (COG; ANBL1221), patients had to have histological verification of neuroblastoma or ganglioneuroblastoma at diagnosis or have tumour cells in bone marrow with increased urinary catecholamine concentrations at diagnosis...
May 23, 2017: Lancet Oncology
https://www.readbyqxmd.com/read/28548996/distal-junctional-failure-following-pediatric-spinal-fusion
#3
Lorena V Floccari, Alvin W Su, Amy L McIntosh, Karl Rathjen, William J Shaughnessy, A Noelle Larson
BACKGROUND: Adjacent segment pathology is a known complication after spinal fusion, but little has been reported on junctional failure. A series of adolescent patients presented with acute distal junctional failure (DJF). We sought to determine any common features of these patients to develop a prevention strategy. METHODS: A retrospective review was conducted of pediatric patients who developed DJF after instrumented spinal fusion performed at 2 institutions from 1999 to 2013...
May 25, 2017: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/28548542/a-systematic-review-of-the-impact-of-educational-programs-on-factors-that-affect-nurses-post-operative-pain-management-for-children
#4
Nahar AlReshidi, Tony Long, Angela Darvill
Despite extensive research in the international arena into pain and its management, there is, as yet, little research on the topic of pain in children in Saudi Arabia and in the Gulf countries generally. A systematic review was conducted to explore the impact of education programs on factors affecting paediatric nurses' postoperative pain management practice. This was done in order to advise the creation of an educational program for nurses in Saudi Arabia. Knowledge about pain, attitudes towards pain, beliefs about children's pain, perceptions of children's reports of pain, self-efficacy with regard to pain management, and perceptions of barriers to optimal practice were all considered to be relevant factors...
May 26, 2017: Compr Child Adolesc Nurs
https://www.readbyqxmd.com/read/28547317/pelvic-pain-in-the-middle-of-the-night-use-of-mri-for-evaluation-of-pediatric-female-pathology-in-the-emergent-setting
#5
Rama S Ayyala, Asef Khwaja, Sudha A Anupindi
Acute pelvic pain in pediatric female patients is a common cause of emergency room visits. Imaging plays a crucial role in the clinical evaluation of these patients. Pelvic pain in female children can result from various pathologies. Ultrasound is the preferred first line imaging study; however, magnetic resonance imaging (MRI) is a helpful adjunct after hours, as it is available 24/7 in many institutions. Advantages of MRI include superior delineation of anatomy and higher tissue contrast resolution, particularly of the small pelvic structures...
May 25, 2017: Emergency Radiology
https://www.readbyqxmd.com/read/28545899/multiple-brain-abscesses-due-to-enterobacter-cloacae-in-an-immune-competent-child
#6
Arushi Gahlot Saini, Vinay Rathore, Chirag Kumar Ahuja, Rajesh Chhabra, Pankaj C Vaidya, Pratibha Singhi
Brain abscesses due to Enterobacteriaceae in immune-competent children are rare, and those due to Enterobacter cloacae are even rarer. We report an interesting case of community-acquired E. cloacae neuroinfection resulting in multiple brain abscesses in a young child with no underlying risk-factors. A 10 year-old-boy presented with low-grade fever, headache, neck pain and progressive deterioration of sensorium. On examination, he was conscious but drowsy with photophobia, normal fundii, meningeal signs, mild hypertonia, brisk muscle stretch reflexes and extensor plantar responses...
May 22, 2017: Journal of Infection and Public Health
https://www.readbyqxmd.com/read/28545800/outcomes-and-satisfaction-in-pediatric-patients-with-chait-cecostomy-tubes
#7
Mark D Bevill, Kristine Bonnett, Angela Arlen, Christopher Cooper, Cheryl Baxter, Douglas W Storm
INTRODUCTION: Patients with spina bifida and other spinal dysraphisms commonly suffer from fecal incontinence and constipation, which can be treated with antegrade continence enemas. Currently, information regarding outcomes and satisfaction in children who have Chait cecostomy tubes is lacking. The aim of our study was to evaluate the effectiveness of Chait cecostomy tubes in management of constipation in children with spinal dysraphisms. MATERIALS AND METHODS: A questionnaire was completed by patients and/or their families during office visits at the University of Iowa or Nationwide Children's Hospital during follow-up pediatric urology office visits...
May 8, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28544343/levels-of-anxiety-in-parents-in-the-24-h-before-and-after-their-child-s-surgery-a-descriptive-study
#8
Laura Pomicino, Elena Maccacari, Sara Buchini
AIMS AND OBJECTIVES: To: a. investigate pre and post-operative anxiety levels in parents of surgical patients; b. identify factors that affect parental anxiety; c. analyze assistance provided and overall parental satisfaction in order to assess if and how this aspect can impact their anxiety level. BACKGROUND: Surgery as an event generates anxiety in children and their parents. Children who are anxious before surgery are likely to develop more postoperative psychological and physiological complications than those who are not...
May 25, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28544180/a-cognitive-behavioral-program-for-parents-of-children-with-chronic-musculoskeletal-pain-a-feasibility-study
#9
C Wiertz, M Goossens, E M Spek, J A Verbunt
BACKGROUND: The purpose of the study is to evaluate the feasibility of a newly developed parent program for parents of children with non-specific chronic musculoskeletal pain. This program is part of the child's interdisciplinary outpatient pain rehabilitation treatment. The goal of the parent program is to change parent's thoughts/behaviour regarding pain with the ultimate intention to further improve their child's functioning. There were two main objectives in the study: First, to evaluate the feasibility of the parent program...
May 23, 2017: European Journal of Pain: EJP
https://www.readbyqxmd.com/read/28543191/methadone-buprenorphine-and-naltrexone-for-the-treatment-of-opioid-use-disorder-in-pregnant-women
#10
Tran H Tran, Brooke L Griffin, Rebecca H Stone, Kathleen M Vest, Timothy J Todd
Pregnant women with opioid use disorder can be treated with methadone, buprenorphine, or naltrexone to reduce opioid use and improve retention to treatment. In this review, we compare the pregnancy outcomes of methadone, buprenorphine, and naltrexone in clinical trials and discuss the potential behavioral and developmental effects of these agents seen in offspring in animal studies. Important clinical considerations in the management of opioid use disorder in pregnant women and their infants are also discussed...
May 24, 2017: Pharmacotherapy
https://www.readbyqxmd.com/read/28542661/-benign-acute-childhood-myositis-clinical-series-and-literature-review
#11
Felipe Cavagnaro S M, Alejandra Aird G, Ingrid Harwardt R, Carmen Gloria Marambio Q
Benign acute childhood myositis (BACM) is a rare clinical condition that mainly affects pre-school and school age-children. It is usually preceded by a viral illness, particularly influenza virus infection. OBJECTIVE: To describe a cluster of BACM cases that were seen in a paediatric unit. PATIENTS AND METHODS: A retrospective series of cases that presented with a clinical picture suggestive of BACM between August and November 2012 in the paediatric emergency department of a private clinic...
April 2017: Revista Chilena de Pediatría
https://www.readbyqxmd.com/read/28541526/maladaptive-coping-and-depressive-symptoms-partially-explain-the-association-between-family-stress-and-pain-related-distress-in-youth-with-ibd
#12
Bonney Reed-Knight, Miranda A L van Tilburg, Rona L Levy, Shelby L Langer, Joan M Romano, Tasha B Murphy, Melissa M DuPen, Andrew D Feld
To extend existing research on the pain burden experienced by youth with inflammatory bowel disease (IBD) by examining the complexity of psychosocial factors involved in pain-related distress. Parents completed measures of family stress and their child's pain-related expressions of distress and coping. Youth with IBD rated their depressive symptoms ( n  = 183 dyads). Mediation analyses were performed using regression-based techniques and bootstrapping. Greater family stress was positively related to children's pain-related expressions of distress and passive coping...
May 24, 2017: Journal of Pediatric Psychology
https://www.readbyqxmd.com/read/28541259/functional-gastrointestinal-disorders-in-children-a-survey-on-clinical-approach-in-the-mediterranean-area
#13
Elena Scarpato, Paolo Quitadamo, Enriqueta Roman, Danijela Jojkic-Pavkov, Sanja Kolacek, Alexandra Papadopoulou, Eleftheria Roma, Raanan Shamir, Michal R B Lev, Branko Lutovac, Veselinka Djurisic, Rok Orel, Aziz Koleilat, Sirin Mneimneh, Vincenzo Coppola, Enrico Corazziari, Annamaria Staiano
OBJECTIVES: Childhood functional gastrointestinal disorders (FGIDs) are common conditions associated with significant morbidity and high healthcare costs. This multicenter study aimed at assessing the clinical approach to infants (0-6 months) and children/adolescents (4-18 years) with suspected FGIDs by pediatricians from the Mediterranean Area. METHODS: A survey evaluating the diagnostic approach, including the use of Rome II and III criteria, and the therapeutic management of some of the most prevalent FGIDs, such as irritable bowel syndrome (IBS), functional constipation (FC), and functional regurgitation (FR), was distributed to a sample of pediatricians...
June 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28541103/finding-the-jewels-in-adversity-reflections-on-a-secondment
#14
Laura Lennard
Laura Lennard, on secondment as Children's Diabetes Nurse, Hemel Hempstead Hospital, West Hertfordshire Hospitals NHS Trust, shares what she has learned from the sometimes painful experience of stepping out of her comfort zone and learning the ropes in a new role.
May 25, 2017: British Journal of Nursing: BJN
https://www.readbyqxmd.com/read/28540807/technical-aspects-of-osteoid-osteoma-ablation-in-children-using-mr-guided-high-intensity-focussed-ultrasound
#15
Pavel S Yarmolenko, Avinash Eranki, Ari Partanen, Haydar Celik, AeRang Kim, Matthew Oetgen, Viktoriya Beskin, Domiciano Santos, Janish Patel, Peter C W Kim, Karun Sharma
BACKGROUND: Osteoid osteoma (OO) is a painful bone tumour occurring in children and young adults. Magnetic resonance imaging-guided high intensity focussed ultrasound (MR-HIFU) allows non-invasive treatment without ionising radiation exposure, in contrast to the current standard of care treatment with radiofrequency ablation (RFA). This report describes technical aspects of MR-HIFU ablation in the first 8 paediatric OO patients treated in a safety and feasibility clinical trial (total enrolment of up to 12 patients)...
April 24, 2017: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/28540574/diagnosis-and-management-of-heterotopic-pregnancy-following-embryo-transfer-clinical-analysis-of-55-cases-from-a-single-institution
#16
Jiangtao Lyu, Hong Ye, Weihua Wang, Yi Lin, Wenjie Sun, Li Lei, Lijuan Hao
OBJECTIVE: The aims of this study were to summarize the clinical features of patients with heterotopic pregnancy (HP) following embryo transfer (ET) and explore the risk factors for miscarriage after surgery. METHODS: All patients with HP following ET treated by surgery between August 2014 and August 2015 in Chongqing Health Center for Women and Children were retrospectively reviewed. RESULTS: Fifty-five patients were identified, including 40 with tubal HP, 9 interstitial HP and 6 cornual HP...
May 24, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/28540197/decision-making-patterns-in-managing-children-with-suspected-biliary-dyskinesia
#17
Warapan Nakayuenyongsuk, Hassan Choudry, Karla Au Yeung, Wikrom Karnsakul
AIM: To explore and to analyze the patterns in decision-making by pediatric gastroenterologists in managing a child with a suspected diagnosis of functional gallbladder disorder (FGBD). METHODS: The questionnaire survey included a case history with right upper quadrant pain and was sent to pediatric gastroenterologists worldwide via an internet list server called the PEDGI Bulletin Board. RESULTS: Differences in decision-making among respondents in managing this case were observed at each level of investigations and management...
May 8, 2017: World Journal of Clinical Pediatrics
https://www.readbyqxmd.com/read/28540195/conversion-from-prolonged-intravenous-fentanyl-infusion-to-enteral-methadone-in-critically-ill-children
#18
Vijay Srinivasan, Daniel Pung, Sean P O'Neill
AIM: To describe our institutional experience with conversion from intravenous (IV) fentanyl infusion directly to enteral methadone and occurrence of withdrawal in critically ill mechanically ventilated children exposed to prolonged sedation and analgesia. METHODS: With Institutional Review Board approval, we retrospectively studied consecutively admitted invasively mechanically ventilated children (0-18 years) sedated with IV fentanyl infusion > 5 d and subsequently converted directly to enteral methadone...
May 8, 2017: World Journal of Clinical Pediatrics
https://www.readbyqxmd.com/read/28538604/acute-gastric-volvulus-successfully-treated-by-endoscopic-reduction-in-a-6-year-old-girl-and-a-review-of-the-japanese-literature
#19
Mitsuhiro Haga, Nobuyuki Sano, Takamichi Kamiyama, Naohiro Dairaku, Mari Ishii, Teruko Nemoto, Hoshiro Suzuki, Hiromi Fujie, Jun Suzuki
A previously healthy 6-year-old girl suddenly developed severe abdominal pain and nausea. She was diagnosed with acute gastric volvulus, and a nasogastric tube was inserted to decompress the stomach. The volvulus did not reduce spontaneously; therefore, we performed endoscopic reduction on day 3 and were able to treat her successfully. We reviewed the Japanese literature on endoscopic reduction for gastric volvulus in children. Fifteen cases have been reported since 1994. There are no reports of perforation during the procedure...
May 23, 2017: Pediatric Emergency Care
https://www.readbyqxmd.com/read/28536038/a-review-of-the-evidence-for-threshold-of-burn-injury
#20
REVIEW
N A Martin, S Falder
INTRODUCTION: Burn injury is common and depth is one measure of severity. Although the depth of burn injury is determined by many factors, the relationship between the temperature of the injurious agent and exposure duration, known as the time-temperature relationship, is widely accepted as one of the cornerstones of burn research. Moritz and Henriques first proposed this relationship in 1947 and their seminal work has been cited extensively. However, over the years, readers have misinterpreted their findings and incorporated misleading information about the time-temperature relationship into a wide range of industrial standards, burn prevention literature and medicolegal opinion...
May 20, 2017: Burns: Journal of the International Society for Burn Injuries
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