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https://www.readbyqxmd.com/read/28732344/visible-light-driven-label-free-photoelectrochemical-immunosensor-based-on-tio2-s-bivo4-ag2s-nanocomposites-for-sensitive-detection-ota
#1
Jinhui Feng, Yueyun Li, Zengqiang Gao, Hui Lv, Xiaobo Zhang, Dawei Fan, Qin Wei
A label-free photoelectrochemical (PEC) platform with high visible-light activity for quantitative detection of the ochratoxin A (OTA) was developed by assembly of Ag2S nanoparticles (NPs) sensitized on titanium dioxide/red blood cell-like shape bismuth vanadate (TiO2/S-BiVO4) electrode via layer-by-layer (LBL) strategy. In this protocol, ascorbic acid was used as an efficient electron donor for scavenging photo-generated holes and inhibiting light driven electron-hole pair recombination. TiO2 has good photoelectric activity and large surface area...
July 13, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28732313/biomechanics-of-cell-rearrangements-in-drosophila
#2
REVIEW
Boris Guirao, Yohanns Bellaïche
To acquire their adequate size and shape, living tissues grow and substantially deform as they develop. To do so, the cells making up the tissue can grow and deform as well, but they can also divide, intercalate and die. Among those cell behaviors, cell intercalation, also named cell rearrangement, is a major contributor to the morphogenesis of many cohesive tissues since it enables tissues to drastically deform as they develop while keeping their cohesiveness and avoiding extreme deformation of their cells...
July 18, 2017: Current Opinion in Cell Biology
https://www.readbyqxmd.com/read/28732300/complete-torsion-of-gallbladder-following-laparoscopic-cholecystectomy-a-case-study
#3
Tomoaki Bekki, Tomoyuki Abe, Hironobu Amano, Nobuaki Fujikuni, Hiroshi Okuda, Tatsunari Sasada, Minoru Yamaki, Tsuyoshi Kobayashi, Toshio Noriyuki, Masahiro Nakahara
INTRODUCTION: Gallbladder torsion is mainly associated with a floating gallbladder. From an anatomical perspective, laparoscopic cholecystectomy is a more optimal treatment than open cholecystectomy. PRESENTATION OF CASE: An 84-year-old woman visited the Onomichi General Hospital because of progressive pain in the right upper quadrant of her abdomen. Physical examination revealed a positive Murphy sign and peritoneal irritation. Laboratory data demonstrated that inflammatory marker levels were increased...
June 29, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28732284/field-free-molecular-orientation-by-delayed-elliptically-polarised-laser%C3%A2-pulses
#4
Anjali Maan, Ashish Tyagi, Vinod Prasad
A theoretical model of NAREX (non-adiabatic rotational excitation) and field-free molecular orientation by a short specific elliptically polarised laser pulses (EPLPs) driving a polar molecule is presented. By choosing the proper value of elliptically polarised field parameters, efficient field-free orientation could be achieved. It is demonstrated that NAREX can be controlled by various laser parameters, out of which pulse shape plays the most significant role. The effect of elliptic parameter on the rotational excitation and orientation dynamics is also under concern...
July 13, 2017: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/28732269/gyral-net-a-new-representation-of-cortical-folding-organization
#5
Hanbo Chen, Yujie Li, Fangfei Ge, Gang Li, Dinggang Shen, Tianming Liu
One distinct feature of the cerebral cortex is its convex (gyri) and concave (sulci) folding patterns. Due to the remarkable complexity and variability of gyral/sulcal shapes, it has been challenging to quantitatively model their organization patterns. Inspired by the observation that the lines of gyral crests can form a connected graph on each brain hemisphere, we propose a new representation of cortical gyri/sulci organization pattern - gyral net, which models cortical architecture from a graph perspective, starting with nodes and edges obtained from the reconstructed cortical surfaces...
July 15, 2017: Medical Image Analysis
https://www.readbyqxmd.com/read/28732206/a-utx-mll4-p300-transcriptional-regulatory-network-coordinately-shapes-active-enhancer-landscapes-for-eliciting-transcription
#6
Shu-Ping Wang, Zhanyun Tang, Chun-Wei Chen, Miho Shimada, Richard P Koche, Lan-Hsin Wang, Tomoyoshi Nakadai, Alan Chramiec, Andrei V Krivtsov, Scott A Armstrong, Robert G Roeder
Enhancer activation is a critical step for gene activation. Here we report an epigenetic crosstalk at enhancers between the UTX (H3K27 demethylase)-MLL4 (H3K4 methyltransferase) complex and the histone acetyltransferase p300. We demonstrate that UTX, in a demethylase activity-independent manner, facilitates conversion of inactive enhancers in embryonic stem cells to an active (H3K4me1(+)/H3K27ac(+)) state by recruiting and coupling the enzymatic functions of MLL4 and p300. Loss of UTX leads to attenuated enhancer activity, characterized by reduced levels of H3K4me1 and H3K27ac as well as impaired transcription...
July 20, 2017: Molecular Cell
https://www.readbyqxmd.com/read/28732182/stim1-regulates-enamel-mineralization-and-ameloblast-modulation
#7
Y Furukawa, N Haruyama, M Nikaido, M Nakanishi, N Ryu, M Oh-Hora, K Kuremoto, K Yoshizaki, Y Takano, I Takahashi
Loss-of-function mutations in the Ca(2+) release-activated Ca(2+) channel genes ORAI1 and STIM1 abolish store-operated Ca(2+) entry (SOCE) and result in ectodermal dysplasia with amelogenesis imperfecta. However, because of the limited availability of patient tissue, analyses of enamel mineralization or possible changes in ameloblast function or morphology have not been possible. Here, we generated mice with ectodermal tissue-specific deletion of Stim1 ( Stim1 cKO [conditional knockout]), Stim2 ( Stim2 cKO), and Stim1 and Stim2 ( Stim1/2 cKO) and analyzed their enamel phenotypes as compared with those of control ( Stim1/2(fl/fl)) animals...
July 1, 2017: Journal of Dental Research
https://www.readbyqxmd.com/read/28732162/dynamical-design-of-spatial-patterns-of-colloidal-suspensions
#8
Nuno Am Araujo, Dmitry Zezyulin, Vladimir Konotop, Margarida M Telo da Gama
We study the collective dynamics of colloidal suspensions in the presence of a time-dependent potential, by means of dynamical density functional theory. We consider a non-linear diffusion equation for the density and show that spatial patterns emerge from a sinusoidal external potential with a time-dependent wavelength. These patterns are characterized by a sinusoidal density with the average wavelength and a Bessel-function envelope with an induced wavelength that depends only on the amplitude of the temporal oscillations...
July 21, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28732091/perfusion-of-surgical-cavity-wall-enhancement-in-early-post-treatment-mr-imaging-may-stratify-the-time-to-progression-in-glioblastoma
#9
Ji Eun Park, Kyoung Hwa Ryu, Ho Sung Kim, Hyo Won Kim, Woo Hyun Shim, Seung Chai Jung, Choong Gon Choi, Sang Joon Kim, Jeong Hoon Kim
OBJECTIVE: To determine if perfusion in surgical cavity wall enhancement (SCWE) obtained in early post-treatment MR imaging can stratify time-to-progression (TTP) in glioblastoma. MATERIALS AND METHODS: This study enrolled 60 glioblastoma patients with more than 5-mm-thick SCWEs as detected on contrast-enhanced MR imaging after concurrent chemoradiation therapy. Two independent readers categorized the shape and perfusion state of SCWEs as nodular or non-nodular and as having positive or negative perfusion compared with the contralateral grey matter on arterial spin labeling (ASL)...
2017: PloS One
https://www.readbyqxmd.com/read/28732067/thromboembolic-adverse-event-study-of-combined-estrogen-progestin-preparations-using-japanese-adverse-drug-event-report-database
#10
Shiori Hasegawa, Toshinobu Matsui, Yuuki Hane, Junko Abe, Haruna Hatahira, Yumi Motooka, Sayaka Sasaoka, Akiho Fukuda, Misa Naganuma, Kouseki Hirade, Yukiko Takahashi, Yasutomi Kinosada, Mitsuhiro Nakamura
Combined estrogen-progestin preparations (CEPs) are associated with thromboembolic (TE) side effects. The aim of this study was to evaluate the incidence of TE using the Japanese Adverse Drug Event Report (JADER) database. Adverse events recorded from April 2004 to November 2014 in the JADER database were obtained from the Pharmaceuticals and Medical Devices Agency (PMDA) website (www.pmda.go.jp). We calculated the reporting odds ratios (RORs) of suspected CEPs, analyzed the time-to-onset profile, and assessed the hazard type using Weibull shape parameter (WSP)...
2017: PloS One
https://www.readbyqxmd.com/read/28732042/numerical-study-on-the-lubrication-performance-of-compression-ring-cylinder-liner-system-with-spherical-dimples
#11
Cheng Liu, Yan-Jun Lu, Yong-Fang Zhang, Sha Li, Norbert Müller
The effects of surface texture on the lubrication performance of a compression ring-cylinder liner system are studied in this paper. By considering the surface roughness of the compression ring and cylinder liner, a mixed lubrication model is presented to investigate the tribological behaviors of a barrel-shaped compression ring-cylinder liner system with spherical dimples on the liner. In order to determine the rupture and reformulation positions of fluid film accurately, the Jacoboson-Floberg-Olsson (JFO) cavitation boundary condition is applied to the mixed lubrication model for ensuring the mass-conservative law...
2017: PloS One
https://www.readbyqxmd.com/read/28731851/the-frequency-of-occurrence-of-fish-shaped-red-blood-cells-in-different-haematologic-disorders
#12
Christoph Robier, Carolin Körber, Franz Quehenberger, Manfred Neubauer, Albert Wölfler
BACKGROUND: Red blood cells (RBC) resembling the silhouette of a fish are rarely observed in peripheral blood (PB) smears. In this study, we determined the frequency of occurrence of fish-shaped RBC in different haematologic diseases. METHODS: We examined PB smears of patients with iron deficiency anaemia (IDA) (n=23), β-thalassaemia minor (BTM) (n=30), sickle cell disease (SCD) (n=7), autoimmune haemolytic anaemia (AIHA) (n=13), microangiopathic haemolytic anaemia (MAHA) (n=11), hereditary sphaerocytosis (HS) (n=4), hereditary elliptocytosis (HE) (n=3), vitamin B12 and folate deficiency (n=15), anaemia in liver disease (LD) (n=17), myelodysplastic syndrome (MDS) (n=15), acute myeloid leukaemia (AML) (n=29), chronic myeloid leukaemia (CML) (n=18), primary myelofibrosis (PMF) (n=12), chronic myelo-monocytic leukaemia (CMML) (n=15) and 21 healthy controls by light microscopy for the occurrence of fish-shaped erythrocytes...
July 21, 2017: Clinical Chemistry and Laboratory Medicine: CCLM
https://www.readbyqxmd.com/read/28731847/the-colorful-world-of-extracellular-electron-shuttles
#13
Nathaniel R Glasser, Scott H Saunders, Dianne K Newman
Descriptions of the changeable, striking colors associated with secreted natural products date back well over a century. These molecules can serve as extracellular electron shuttles (EESs) that permit microbes to access substrates at a distance. In this review, we argue that the colorful world of EESs has been too long neglected. Rather than simply serving as a diagnostic attribute of a particular microbial strain, redox-active natural products likely play fundamental, underappreciated roles in the biology of their producers, particularly those that inhabit biofilms...
July 21, 2017: Annual Review of Microbiology
https://www.readbyqxmd.com/read/28731829/pattern-and-process-in-the-comparative-study-of-convergent-evolution
#14
D Luke Mahler, Marjorie G Weber, Catherine E Wagner, Travis Ingram
Understanding processes that have shaped broad-scale biodiversity patterns is a fundamental goal in evolutionary biology. The development of phylogenetic comparative methods has yielded a tool kit for analyzing contemporary patterns by explicitly modeling processes of change in the past, providing neontologists tools for asking questions previously accessible only for select taxa via the fossil record or laboratory experimentation. The comparative approach, however, differs operationally from alternative approaches to studying convergence in that, for studies of only extant species, convergence must be inferred using evolutionary process models rather than being directly measured...
August 2017: American Naturalist
https://www.readbyqxmd.com/read/28731812/3d-printed-visceral-aneurysm-models-based-on-ct-data-for-simulations-of-endovascular-embolization-evaluation-of-size-and-shape-accuracy
#15
Eisuke Shibata, Hidemasa Takao, Shiori Amemiya, Kuni Ohtomo
OBJECTIVE: The objective of this study is to verify the accuracy of 3D-printed hollow models of visceral aneurysms created from CT angiography (CTA) data, by evaluating the sizes and shapes of aneurysms and related arteries. SUBJECTS AND METHODS: From March 2006 to August 2015, 19 true visceral aneurysms were embolized via interventional radiologic treatment provided by the radiology department at our institution; aneurysms with bleeding (n = 3) or without thin-slice (< 1 mm) preembolization CT data (n = 1) were excluded...
August 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28731797/quantitative-genetic-variation-in-and-environmental-effects-on-pathogen-resistance-and-temperature-dependent-disease-severity-in-a-wild-trout
#16
Paul Vincent Debes, Riho Gross, Anti Vasemägi
Health after pathogen contact varies among individuals because of differences in pathogen load (which is limited by resistance) and disease severity in response to pathogen load (which is limited by tolerance). To understand pathogen-induced host evolution, it is critical to know not only the relative contributions of nongenetic and genetic variation to resistance and tolerance but also how they change environmentally. We quantified nongenetic and genetic variation in parasite load and the associated temperature-dependent disease among trout siblings from two rivers...
August 2017: American Naturalist
https://www.readbyqxmd.com/read/28731796/bees-without-flowers-before-peak-bloom-diverse-native-bees-find-insect-produced-honeydew-sugars
#17
Joan M Meiners, Terry L Griswold, David J Harris, S K Morgan Ernest
Bee foragers respond to complex visual, olfactory, and extrasensory cues to optimize searches for floral rewards. Their abilities to detect and distinguish floral colors, shapes, volatiles, and ultraviolet signals and even gauge nectar availability from changes in floral humidity or electric fields are well studied. Bee foraging behaviors in the absence of floral cues, however, are rarely considered. We observed 42 species of wild bees visiting inconspicuous, nonflowering shrubs during early spring in a protected Mediterranean habitat...
August 2017: American Naturalist
https://www.readbyqxmd.com/read/28731776/predicting-flory-huggins-%C3%AF-from-simulations
#18
Wenlin Zhang, Enrique D Gomez, Scott T Milner
We introduce a method, based on a novel thermodynamic integration scheme, to extract the Flory-Huggins χ parameter as small as 10^{-3}kT for polymer blends from molecular dynamics (MD) simulations. We obtain χ for the archetypical coarse-grained model of nonpolar polymer blends: flexible bead-spring chains with different Lennard-Jones interactions between A and B monomers. Using these χ values and a lattice version of self-consistent field theory (SCFT), we predict the shape of planar interfaces for phase-separated binary blends...
July 7, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28731746/transference-of-fermi-contour-anisotropy-to-composite-fermions
#19
Insun Jo, K A Villegas Rosales, M A Mueed, L N Pfeiffer, K W West, K W Baldwin, R Winkler, Medini Padmanabhan, M Shayegan
There has been a surge of recent interest in the role of anisotropy in interaction-induced phenomena in two-dimensional (2D) charged carrier systems. A fundamental question is how an anisotropy in the energy-band structure of the carriers at zero magnetic field affects the properties of the interacting particles at high fields, in particular of the composite fermions (CFs) and the fractional quantum Hall states (FQHSs). We demonstrate here tunable anisotropy for holes and hole-flux CFs confined to GaAs quantum wells, via applying in situ in-plane strain and measuring their Fermi wave vector anisotropy through commensurability oscillations...
July 7, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28731665/-nummular-dermatitis-report-of-two-cases-in-children
#20
Jacinto Martínez-Blanco, Verónica García-González, Javier González-García, Cristina Suárez-Castañón
Nummular eczema or dermatitis is an uncommon paediatric pathology. It is presented as red-purplish small papules and vesicles that join to form exudative circular patches and then to eczematous or lichenified patches with discoid shape. The lesions appear predominantly on the extensor surface of extremities, although they can appear in trunk, hands or feet. This pathology has a clinical diagnosis; only few cases require complementary test. The topical corticosteroids are the mainstay of the treatment, and the causal treatment whether an infectious trigger is found...
August 1, 2017: Archivos Argentinos de Pediatría
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