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https://www.readbyqxmd.com/read/28335567/cross-regulation-between-transposable-elements-and-host-dna-replication
#1
REVIEW
Mikel Zaratiegui
Transposable elements subvert host cellular functions to ensure their survival. Their interaction with the host DNA replication machinery indicates that selective pressures lead them to develop ancestral and convergent evolutionary adaptations aimed at conserved features of this fundamental process. These interactions can shape the co-evolution of the transposons and their hosts.
March 21, 2017: Viruses
https://www.readbyqxmd.com/read/28335516/marine-diterpenes-molecular-modeling-of-thrombin-inhibitors-with-potential-biotechnological-application-as-an-antithrombotic
#2
Rebeca Cristina Costa Pereira, André Luiz Lourenço, Luciana Terra, Paula Alvarez Abreu, Valéria Laneuville Teixeira, Helena Carla Castro
Thrombosis related diseases are among the main causes of death and incapacity in the world. Despite the existence of antithrombotic agents available for therapy, they still present adverse effects like hemorrhagic risks which justify the search for new options. Recently, pachydictyol A, isopachydictyol A, and dichotomanol, three diterpenes isolated from Brazilian marine brown alga Dictyota menstrualis were identified as potent antithrombotic molecules through inhibition of thrombin, a key enzyme of coagulation cascade and a platelet agonist...
March 20, 2017: Marine Drugs
https://www.readbyqxmd.com/read/28335501/communication-matters-exploring-the-intersection-of-family-and-practitioner-end-of-life-communication
#3
Leah M Omilion-Hodges, Nathan M Swords
After establishing a baseline understanding of some of the factors that influence and shape family end of life communication, empirical research centered on the communication tendencies of nationally-recognized palliative care clinicians is presented. Because death is no longer confined to the bedroom and individuals are increasingly turning to hospitals and health care institutes to assist with end of life, the role of palliative care practitioners is vital. To that end, common communication-rooted issues that may transpire among various medical personnel are explored...
March 19, 2017: Behavioral Sciences
https://www.readbyqxmd.com/read/28335486/implicit-regularization-for-reconstructing-3d-building-rooftop-models-using-airborne-lidar-data
#4
Jaewook Jung, Yoonseok Jwa, Gunho Sohn
With rapid urbanization, highly accurate and semantically rich virtualization of building assets in 3D become more critical for supporting various applications, including urban planning, emergency response and location-based services. Many research efforts have been conducted to automatically reconstruct building models at city-scale from remotely sensed data. However, developing a fully-automated photogrammetric computer vision system enabling the massive generation of highly accurate building models still remains a challenging task...
March 19, 2017: Sensors
https://www.readbyqxmd.com/read/28335425/linear-mathematical-model-for-seam-tracking-with-an-arc-sensor-in-p-gmaw-processes
#5
Wenji Liu, Liangyu Li, Ying Hong, Jianfeng Yue
Arc sensors have been used in seam tracking and widely studied since the 80s and commercial arc sensing products for T and V shaped grooves have been developed. However, it is difficult to use these arc sensors in narrow gap welding because the arc stability and sensing accuracy are not satisfactory. Pulse gas melting arc welding (P-GMAW) has been successfully applied in narrow gap welding and all position welding processes, so it is worthwhile to research P-GMAW arc sensing technology. In this paper, we derived a linear mathematical P-GMAW model for arc sensing, and the assumptions for the model are verified through experiments and finite element methods...
March 14, 2017: Sensors
https://www.readbyqxmd.com/read/28335411/how-the-cobra-got-its-flesh-eating-venom-cytotoxicity-as-a-defensive-innovation-and-its-co-evolution-with-hooding-aposematic-marking-and-spitting
#6
Nadya Panagides, Timothy N W Jackson, Maria P Ikonomopoulou, Kevin Arbuckle, Rudolf Pretzler, Daryl C Yang, Syed A Ali, Ivan Koludarov, James Dobson, Brittany Sanker, Angelique Asselin, Renan C Santana, Iwan Hendrikx, Harold van der Ploeg, Jeremie Tai-A-Pin, Romilly van den Bergh, Harald M I Kerkkamp, Freek J Vonk, Arno Naude, Morné A Strydom, Louis Jacobsz, Nathan Dunstan, Marc Jaeger, Wayne C Hodgson, John Miles, Bryan G Fry
The cytotoxicity of the venom of 25 species of Old World elapid snake was tested and compared with the morphological and behavioural adaptations of hooding and spitting. We determined that, contrary to previous assumptions, the venoms of spitting species are not consistently more cytotoxic than those of closely related non-spitting species. While this correlation between spitting and non-spitting was found among African cobras, it was not present among Asian cobras. On the other hand, a consistent positive correlation was observed between cytotoxicity and utilisation of the defensive hooding display that cobras are famous for...
March 13, 2017: Toxins
https://www.readbyqxmd.com/read/28335368/shape-evolution-of-hierarchical-w18o49-nanostructures-a-systematic-investigation-of-the-growth-mechanism-properties-and-morphology-dependent-photocatalytic-activities
#7
Guojuan Hai, Jianfeng Huang, Liyun Cao, Yanni Jie, Jiayin Li, Xing Wang
Hierarchical tungsten oxide assemblies such as spindle-like structures, flowers with sharp petals, nanowires and regular hexagonal structures are successfully synthesized via a solvothermal reduction method by simply adjusting the reaction conditions. On the basis of the experimental results, it is determined that the reaction time significantly influences the phase transition, microstructure and photocatalytic activity of the prepared samples. The possible mechanisms for the morphology evolution process have been systematically proposed...
December 14, 2016: Nanomaterials
https://www.readbyqxmd.com/read/28335363/antimicrobial-antioxidant-and-anticancer-activities-of-biosynthesized-silver-nanoparticles-using-marine-algae-ecklonia-cava
#8
Jayachandran Venkatesan, Se-Kwon Kim, Min Suk Shim
Green synthesis of silver nanoparticles (AgNPs) has gained great interest as a simple and eco-friendly alternative to conventional chemical methods. In this study, AgNPs were synthesized by using extracts of marine algae Ecklonia cava as reducing and capping agents. The formation of AgNPs using aqueous extract of Ecklonia cava was confirmed visually by color change and their surface plasmon resonance peak at 418 nm, measured by UV-visible spectroscopy. The size, shape, and morphology of the biosynthesized AgNPs were observed by transmission electron microscopy and dynamic light scattering analysis...
December 6, 2016: Nanomaterials
https://www.readbyqxmd.com/read/28335350/shape-and-charge-of-gold-nanomaterials-influence-survivorship-oxidative-stress-and-moulting-of-daphnia-magna
#9
Fatima Nasser, Adam Davis, Eugenia Valsami-Jones, Iseult Lynch
Engineered nanomaterials (ENMs) are materials with at least one dimension between 1-100 nm. The small size of ENMs results in a large surface area to volume ratio, giving ENMs novel characteristics that are not traditionally exhibited by larger bulk materials. Coupled with large surface area is an enormous capacity for surface functionalization of ENMs, e.g., with different ligands or surface changes, leading to an almost infinite array of variability of ENMs. Here we explore the effects of various shaped (spheres, rods) and charged (negative, positive) gold ENMs on Daphnia magna (D...
November 25, 2016: Nanomaterials
https://www.readbyqxmd.com/read/28335333/plant-mediated-green-synthesis-of-cuo-nanoparticles-comparison-of-toxicity-of-engineered-and-plant-mediated-cuo-nanoparticles-towards-daphnia-magna
#10
Sadia Saif, Arifa Tahir, Tayyaba Asim, Yongsheng Chen
Research on green production methods for metal oxide nanoparticles (NPs) is growing, with the objective to overcome the potential hazards of these chemicals for a safer environment. In this study, facile, ecofriendly synthesis of copper oxide (CuO) nanoparticles was successfully achieved using aqueous extract of Pterospermum acerifolium leaves. P. acerifolium-fabricated CuO nanoparticles were further characterized by UV-Visible spectroscopy, field emission scanning electron microscopy (FE-SEM), energy dispersive X-ray (EDX), Fourier transform infrared spectroscopy (FTIR), X-ray photoelectron spectroscopy (XPS) and dynamic light scattering (DLS)...
November 9, 2016: Nanomaterials
https://www.readbyqxmd.com/read/28335314/effects-of-g-quadruplex-topology-on-electronic-transfer-integrals
#11
Wenming Sun, Daniele Varsano, Rosa Di Felice
G-quadruplex is a quadruple helical form of nucleic acids that can appear in guanine-rich parts of the genome. The basic unit is the G-tetrad, a planar assembly of four guanines connected by eight hydrogen bonds. Its rich topology and its possible relevance as a drug target for a number of diseases have stimulated several structural studies. The superior stiffness and electronic π-π overlap between consecutive G-tetrads suggest exploitation for nanotechnologies. Here we inspect the intimate link between the structure and the electronic properties, with focus on charge transfer parameters...
October 15, 2016: Nanomaterials
https://www.readbyqxmd.com/read/28335296/controlled-mechanical-cracking-of-metal-films-deposited-on-polydimethylsiloxane-pdms
#12
Andreas Polywka, Luca Stegers, Oliver Krauledat, Thomas Riedl, Timo Jakob, Patrick Görrn
Stretchable large area electronics conform to arbitrarily-shaped 3D surfaces and enables comfortable contact to the human skin and other biological tissue. There are approaches allowing for large area thin films to be stretched by tens of percent without cracking. The approach presented here does not prevent cracking, rather it aims to precisely control the crack positions and their orientation. For this purpose, the polydimethylsiloxane (PDMS) is hardened by exposure to ultraviolet radiation (172 nm) through an exposure mask...
September 9, 2016: Nanomaterials
https://www.readbyqxmd.com/read/28335294/preparation-characterization-and-manipulation-of-conjugates-between-gold-nanoparticles-and-dna
#13
Gennady Eidelshtein, Moran Fattal, Gavriel Avishai, Benjamin Kempinski, Clelia Giannini, Alexander Kotlyar
Here we described the preparation and characterization by atomic force microscopy of dumbbell-shaped conjugates between 450 bp double-stranded DNA polymer, poly(dG)-poly(dC), and 5 nm gold nanoparticles (GNPs). We have demonstrated that the size of the nanoparticles in the conjugates can be increased in a controlled fashion. Application of the conjugates for measuring the electrical conductivity of DNA is discussed.
September 8, 2016: Nanomaterials
https://www.readbyqxmd.com/read/28335274/metallic-nanostructures-based-on-dna-nanoshapes
#14
REVIEW
Boxuan Shen, Kosti Tapio, Veikko Linko, Mauri A Kostiainen, Jari Jussi Toppari
Metallic nanostructures have inspired extensive research over several decades, particularly within the field of nanoelectronics and increasingly in plasmonics. Due to the limitations of conventional lithography methods, the development of bottom-up fabricated metallic nanostructures has become more and more in demand. The remarkable development of DNA-based nanostructures has provided many successful methods and realizations for these needs, such as chemical DNA metallization via seeding or ionization, as well as DNA-guided lithography and casting of metallic nanoparticles by DNA molds...
August 10, 2016: Nanomaterials
https://www.readbyqxmd.com/read/28335263/enhanced-deposition-uniformity-via-an-auxiliary-electrode-in-massive-electrospinning
#15
Dezhi Wu, Zhiming Xiao, Lei Deng, Yu Sun, Qiulin Tan, Linxi Dong, Shaohua Huang, Rui Zhu, Yifang Liu, Wanxi Zheng, Yang Zhao, Lingyun Wang, Daoheng Sun
Uniform deposition of nanofibers in the massive electrospinning process is critical in the industrial applications of nanofibers. Tip-Induced Electrospinning (TIE) is a cost-effective large-scale nanofiber-manufacturing method, but it has poor deposition uniformity. An auxiliary conductive electrode connected to the emitting electrode was introduced to improve the deposition uniformity of the nanofibers. The effects of the auxiliary electrode shape, the tilted angles and the position of the boat-like electrode on the electric field distribution, the diameter of the nanofibers, the jet control and the deposition uniformity were explored by using finite element analysis of the electric field and experiments...
July 22, 2016: Nanomaterials
https://www.readbyqxmd.com/read/28335237/dna-sequencing-by-hexagonal-boron-nitride-nanopore-a-computational-study
#16
Liuyang Zhang, Xianqiao Wang
The single molecule detection associated with DNA sequencing has motivated intensive efforts to identify single DNA bases. However, little research has been reported utilizing single-layer hexagonal boron nitride (hBN) for DNA sequencing. Here we employ molecular dynamics simulations to explore pathways for single-strand DNA (ssDNA) sequencing by nanopore on the hBN sheet. We first investigate the adhesive strength between nucleobases and the hBN sheet, which provides the foundation for the hBN-base interaction and nanopore sequencing mechanism...
June 6, 2016: Nanomaterials
https://www.readbyqxmd.com/read/28335236/complex-morphology-metal-based-nanostructures-fabrication-characterization-and-applications
#17
REVIEW
Antonella Gentile, Francesco Ruffino, Maria Grazia Grimaldi
Due to their peculiar qualities, metal-based nanostructures have been extensively used in applications such as catalysis, electronics, photography, and information storage, among others. New applications for metals in areas such as photonics, sensing, imaging, and medicine are also being developed. Significantly, most of these applications require the use of metals in the form of nanostructures with specific controlled properties. The properties of nanoscale metals are determined by a set of physical parameters that include size, shape, composition, and structure...
June 6, 2016: Nanomaterials
https://www.readbyqxmd.com/read/28335232/the-influence-of-modified-silica-nanomaterials-on-adult-stem-cell-culture
#18
Luigi Tarpani, Francesco Morena, Marta Gambucci, Giulia Zampini, Giuseppina Massaro, Chiara Argentati, Carla Emiliani, Sabata Martino, Loredana Latterini
The preparation of tailored nanomaterials able to support cell growth and viability is mandatory for tissue engineering applications. In the present work, silica nanoparticles were prepared by a sol-gel procedure and were then functionalized by condensation of amino groups and by adsorption of silver nanoparticles. Transmission electron microscopy (TEM) imaging was used to establish the morphology and the average dimensions of about 130 nm, which were not affected by the functionalization. The three silica samples were deposited (1 mg/mL) on cover glasses, which were used as a substrate to culture adult human bone marrow-mesenchymal stem cells (hBM-MSCs) and human adipose-derived stem cells (hASCs)...
June 4, 2016: Nanomaterials
https://www.readbyqxmd.com/read/28335223/ultraviolet-plasmonic-aluminium-nanoparticles-for-highly-efficient-light-incoupling-on-silicon-solar-cells
#19
Yinan Zhang, Boyuan Cai, Baohua Jia
Plasmonic metal nanoparticles supporting localized surface plasmon resonances have attracted a great deal of interest in boosting the light absorption in solar cells. Among the various plasmonic materials, the aluminium nanoparticles recently have become a rising star due to their unique ultraviolet plasmonic resonances, low cost, earth-abundance and high compatibility with the complementary metal-oxide semiconductor (CMOS) manufacturing process. Here, we report some key factors that determine the light incoupling of aluminium nanoparticles located on the front side of silicon solar cells...
May 24, 2016: Nanomaterials
https://www.readbyqxmd.com/read/28335201/size-and-shape-dependent-antibacterial-studies-of-silver-nanoparticles-synthesized-by-wet-chemical-routes
#20
Muhammad Akram Raza, Zakia Kanwal, Anum Rauf, Anjum Nasim Sabri, Saira Riaz, Shahzad Naseem
Silver nanoparticles (AgNPs) of different shapes and sizes were prepared by solution-based chemical reduction routes. Silver nitrate was used as a precursor, tri-sodium citrate (TSC) and sodium borohydride as reducing agents, while polyvinylpyrrolidone (PVP) was used as a stabilizing agent. The morphology, size, and structural properties of obtained nanoparticles were characterized by scanning electron microscopy (SEM), UV-visible spectroscopy (UV-VIS), and X-ray diffraction (XRD) techniques. Spherical AgNPs, as depicted by SEM, were found to have diameters in the range of 15 to 90 nm while lengths of the edges of the triangular particles were about 150 nm...
April 15, 2016: Nanomaterials
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