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https://www.readbyqxmd.com/read/28324153/epigenetics-in-the-pathogenesis-of-ra
#1
REVIEW
Caroline Ospelt, Steffen Gay, Kerstin Klein
Epigenetic modifications can stably alter gene expression and have been shown to be important in the maintenance of cell type-specific functions as well as in cell differentiation, e.g., in T and B cell maturation. In RA, alterations in DNA methylation, histone modifications, and microRNA expression have been found in immune as well as in stromal cells. These changes in the epigenome in RA patients influence key inflammatory and matrix-degrading pathways and are suspected to play a major role in the pathogenesis of RA...
March 21, 2017: Seminars in Immunopathology
https://www.readbyqxmd.com/read/28318597/the-timing-of-surgery-of-antenatally-diagnosed-choledochal-malformations-a-descriptive-analysis-of-a-26-year-nationwide-cohort
#2
Maria H A van den Eijnden, Ruben H de Kleine, Ivo de Blaauw, Paul M J G Peeters, Bart G P Koot, Matthijs W N Oomen, Cornelius E J Sloots, Wim G van Gemert, David C van der Zee, L W Ernest van Heurn, Henkjan J Verkade, Jim C H Wilde, Jan B F Hulscher
INTRODUCTION: Choledochal malformations (CMs) are increasingly diagnosed antenatally. There is a dilemma between early surgery to prevent CM-related symptoms and postponing surgery to reduce complications. We aimed to identify the optimal timing of surgery in asymptomatic neonates with antenatally diagnosed CM and to identify predictors for development of symptoms. METHODS: Using the Netherlands Study group on CHoledochal Cyst/malformation (NeSCHoc) we retrospectively collected demographic, biochemical and surgical data from all Dutch patients with an antenatally detected CM...
March 12, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/28304157/characterization-of-gas-phase-organics-using-proton-transfer-reaction-time-of-flight-mass-spectrometry-aircraft-turbine-engines
#3
Dogushan Kilic, Benjamin T Brem, Felix Klein, Imad El-Haddad, Lukas Durdina, Theo Rindlisbacher, Ari Setyan, Rujin Huang, Jing Wang, Jay G Slowik, Urs Baltensperger, Andre S H Prevot
Nonmethane organic gas emissions (NMOGs) from in-service aircraft turbine engines were investigated using a proton transfer reaction time-of-flight mass spectrometer (PTR-ToF-MS) at an engine test facility at Zurich Airport, Switzerland. Experiments consisted of 60 exhaust samples for seven engine types (used in commercial aviation) from two manufacturers at thrust levels ranging from idle to takeoff. Emission indices (EIs) for more than 200 NMOGs were quantified, and the functional group fractions (including acids, carbonyls, aromatics, and aliphatics) were calculated to characterize the exhaust chemical composition at different engine operation modes...
March 17, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28302722/amyloid-%C3%AE-oligomers-transiently-inhibit-amp-activated-kinase-and-cause-metabolic-defects-in-hippocampal-neurons
#4
Gisele S Seixas da Silva, Helen M Melo, Mychael V Lourenco, Natalia de M Lyra E Silva, Marcelo B de Carvalho, Soniza Alves-Leon, Jorge M de Souza, William L Klein, Wagner S da-Silva, Sergio T Ferreira, Fernanda G De Felice
AMP-activated kinase (AMPK) is a key player in energy sensing and metabolic reprogramming under cellular energy restriction. Several studies have linked impaired AMPK function to peripheral metabolic diseases such as diabetes. However, the impact of neurological disorders, such as Alzheimer disease (AD), on AMPK function and downstream effects of altered AMPK activity on neuronal metabolism have been investigated only recently. Here, we report the impact of A β oligomers (AβOs), synaptotoxins that accumulate in AD brains, on neuronal AMPK activity...
March 16, 2017: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/28300164/role-of-purinergic-signaling-in-experimental-pneumococcal-meningitis
#5
Marco Zierhut, Susanne Dyckhoff, Ilias Masouris, Matthias Klein, Sven Hammerschmidt, Hans-Walter Pfister, Korcan Ayata, Marco Idzko, Uwe Koedel
Excessive neutrophilic inflammation contributes to brain pathology and adverse outcome in pneumococcal meningitis (PM). Recently, we identified the NLRP3 inflammasome/interleukin (IL)-1β pathway as a key driver of inflammation in PM. A critical membrane receptor for NLRP3 inflammasome activation is the ATP-activated P2 purinoceptor (P2R) P2X7. Thus, we hypothesized involvement of ATP and P2Rs in PM. The functional role of ATP was investigated in a mouse meningitis model using P2R antagonists. Brain expression of P2Rs was assessed by RT-PCR...
March 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28295548/interaction-between-stress-induced-by-competition-predation-and-an-insecticide-on-the-response-of-aquatic-invertebrates
#6
Paul J Van den Brink, Sylvan L Klein, Andreu Rico
This study investigated effects of species interactions like competition and (intraguild) predation on the sensitivity of aquatic organisms to the insecticide chlorpyrifos. In the first experiment, combined effects of chlorpyrifos and different levels of intra- and inter-specific interaction were assessed on Gammarus pulex survival using Asellus aquaticus as an interacting species. Intra- and inter-specific interactions increased the time to extinction of G. pulex up to a factor of two, most likely due to the cannibalistic nature of G...
March 10, 2017: Environmental Toxicology and Chemistry
https://www.readbyqxmd.com/read/28295418/technical-note-on-the-accuracy-of-parametric-two-parameter-cross-section-models-in-dual-energy-ct-applications
#7
Dong Han, Mariela A Porras-Chaverri, Joseph A O'Sullivan, David G Politte, Jeffrey F Williamson
PURPOSE: To evaluate and compare the theoretically achievable accuracy of two families of two-parameter photon cross-section models: basis vector model (BVM) and modified parametric fit model (mPFM). METHOD: The modified PFM assumes that photoelectric absorption and scattering cross sections can be accurately represented by power functions in effective atomic number and / or energy plus the Klein-Nishina cross section, along with empirical corrections that enforce exact prediction of elemental cross sections...
March 15, 2017: Medical Physics
https://www.readbyqxmd.com/read/28293274/optimally-repeatable-kinetic-model-variant-for-myocardial-blood-flow-measurements-with-82-rb-pet
#8
Adrian F Ocneanu, Robert A deKemp, Jennifer M Renaud, Andy Adler, Rob S B Beanlands, Ran Klein
Purpose. Myocardial blood flow (MBF) quantification with (82)Rb positron emission tomography (PET) is gaining clinical adoption, but improvements in precision are desired. This study aims to identify analysis variants producing the most repeatable MBF measures. Methods. 12 volunteers underwent same-day test-retest rest and dipyridamole stress imaging with dynamic (82)Rb PET, from which MBF was quantified using 1-tissue-compartment kinetic model variants: (1) blood-pool versus uptake region sampled input function (Blood/Uptake-ROI), (2) dual spillover correction (SOC-On/Off), (3) right blood correction (RBC-On/Off), (4) arterial blood transit delay (Delay-On/Off), and (5) distribution volume (DV) constraint (Global/Regional-DV)...
2017: Computational and Mathematical Methods in Medicine
https://www.readbyqxmd.com/read/28292938/combinatorial-screening-of-pancreatic-adenocarcinoma-reveals-sensitivity-to-drug-combinations-including-bromodomain-inhibitor-plus-neddylation-inhibitor
#9
Casey G Langdon, James T Platt, Robert E Means, Pinar Iyidogan, Ramanaiah Mamillapalli, Michael Klein, Matthew A Held, Jong Woo Lee, Ja Seok Koo, Christos Hatzis, Howard S Hochster, David F Stern
Pancreatic adenocarcinoma (PDAC) is the fourth most common cause of cancer death in the United States. PDAC is difficult to manage effectively, with a five-year survival rate of only 5%. PDAC is largely driven by activating KRAS mutations, and as such, cannot be directly targeted with therapeutic agents that affect the activated protein. Instead, inhibition of downstream signaling and other targets will be necessary to effectively manage PDAC. Here, we describe a tiered single-agent and combination compound screen to identify targeted agents that impair growth of a panel of PDAC cell lines...
March 14, 2017: Molecular Cancer Therapeutics
https://www.readbyqxmd.com/read/28288255/inform-parents-protect-high-school-blood-donors
#10
Anne F Eder, Harvey G Klein, Cathy Conry-Cantilena
No abstract text is available yet for this article.
March 13, 2017: JAMA Pediatrics
https://www.readbyqxmd.com/read/28286963/rehabilitation-and-education-are-underutilized-for-mild-stroke-and-tia-sufferers
#11
Steven G Faux, Pooja Arora, Christine T Shiner, Angelica G Thompson-Butel, Linda A Klein
PURPOSE: Transient ischemic attack (TIA) and mild stroke represent a large proportion of cerebrovascular events, at high risk of being followed by recurrent, serious events. The importance of early education addressing risk management, secondary prevention and lifestyle modifications is the centerpiece of further stroke prevention. However, delivering education and rehabilitation to this population can be complex and challenging. METHODS: Via synthesis of a narrative review and clinical experience, we explore the unique and inherent complexities of rehabilitation management and education provision for patients following mild stroke and TIA...
March 12, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28286003/recognition-of-histone-h3k14-acylation-by-morf
#12
Brianna J Klein, Johayra Simithy, Xiaolu Wang, JaeWoo Ahn, Forest H Andrews, Yi Zhang, Jacques Côté, Xiaobing Shi, Benjamin A Garcia, Tatiana G Kutateladze
The monocytic leukemia zinc-finger protein-related factor (MORF) is a transcriptional coactivator and a catalytic subunit of the lysine acetyltransferase complex implicated in cancer and developmental diseases. We have previously shown that the double plant homeodomain finger (DPF) of MORF is capable of binding to acetylated histone H3. Here we demonstrate that the DPF of MORF recognizes many newly identified acylation marks. The mass spectrometry study provides comprehensive analysis of H3K14 acylation states in vitro and in vivo...
March 9, 2017: Structure
https://www.readbyqxmd.com/read/28285916/discovery-and-optimization-of-2-pyridinone-aminal-integrase-strand-transfer-inhibitors-for-the-treatment-of-hiv
#13
John D Schreier, Mark W Embrey, Izzat T Raheem, Guillaume Barbe, Louis-Charles Campeau, David Dubost, Jamie McCabe Dunn, Jay Grobler, Timothy J Hartingh, Daria J Hazuda, Daniel Klein, Michael D Miller, Keith P Moore, Natalie Nguyen, Natasa Pajkovic, David A Powell, Vanessa Rada, John M Sanders, John Sisko, Thomas G Steele, John Wai, Abbas Walji, Min Xu, Paul J Coleman
HIV integrase strand transfer inhibitors (InSTIs) represent an important class of antiviral therapeutics with proven efficacy and excellent tolerability for the treatment of HIV infections. In 2007, Raltegravir became the first marketed strand transfer inhibitor pioneering the way to a first-line therapy for treatment-naïve patients. Challenges with this class of therapeutics remain, including frequency of the dosing regimen and the genetic barrier to resistance. To address these issues, research towards next-generation integrase inhibitors has focused on imparting potency against RAL-resistent mutants and improving pharmacokinetic profiles...
February 20, 2017: Bioorganic & Medicinal Chemistry Letters
https://www.readbyqxmd.com/read/28283061/functional-selectivity-in-cytokine-signaling-revealed-through-a-pathogenic-epo-mutation
#14
Ah Ram Kim, Jacob C Ulirsch, Stephan Wilmes, Ekrem Unal, Ignacio Moraga, Musa Karakukcu, Daniel Yuan, Shideh Kazerounian, Nour J Abdulhay, David S King, Namrata Gupta, Stacey B Gabriel, Eric S Lander, Turkan Patiroglu, Alper Ozcan, Mehmet Akif Ozdemir, K Christopher Garcia, Jacob Piehler, Hanna T Gazda, Daryl E Klein, Vijay G Sankaran
Cytokines are classically thought to stimulate downstream signaling pathways through monotonic activation of receptors. We describe a severe anemia resulting from a homozygous mutation (R150Q) in the cytokine erythropoietin (EPO). Surprisingly, the EPO R150Q mutant shows only a mild reduction in affinity for its receptor but has altered binding kinetics. The EPO mutant is less effective at stimulating erythroid cell proliferation and differentiation, even at maximally potent concentrations. While the EPO mutant can stimulate effectors such as STAT5 to a similar extent as the wild-type ligand, there is reduced JAK2-mediated phosphorylation of select downstream targets...
March 9, 2017: Cell
https://www.readbyqxmd.com/read/28271572/problem-behaviour-and-psychosocial-functioning-in-young-children-with-williams-syndrome-parent-and-teacher-perspectives
#15
B P Klein-Tasman, K Lee
BACKGROUND: There is sparse literature about problem behaviour in young children with Williams syndrome (WS) and little consideration of the perspectives of multiple respondents. METHODS: Problem behaviour of 35 children with WS ages 2 to 6 was examined based on both parent and teacher report using the Achenbach preschool forms. RESULTS: The most prominent areas of difficulty based on both parent and teacher report were attention problems, pervasive developmental problems and emotion reactivity difficulties...
March 7, 2017: Journal of Intellectual Disability Research: JIDR
https://www.readbyqxmd.com/read/28264691/endothelial-responses-of-the-alveolar-barrier-in-vitro-in-a-dose-controlled-exposure-to-diesel-exhaust-particulate-matter
#16
Sebastian G Klein, Sébastien Cambier, Jennifer Hennen, Sylvain Legay, Tommaso Serchi, Inge Nelissen, Aline Chary, Elisa Moschini, Andreas Krein, Brunhilde Blömeke, Arno C Gutleb
BACKGROUND: During the last 250 years, the level of exposure to combustion-derived particles raised dramatically in western countries, leading to increased particle loads in the ambient air. Among the environmental particles, diesel exhaust particulate matter (DEPM) plays a special role because of its omnipresence and reported effects on human health. During recent years, a possible link between air pollution and the progression of atherosclerosis is recognized. A central effect of DEPM is their impact on the endothelium, especially of the alveolar barrier...
March 6, 2017: Particle and Fibre Toxicology
https://www.readbyqxmd.com/read/28263166/the-red-cell-storage-lesion-s-of-dogs-and-men
#17
REVIEW
Harvey G Klein
The advent of preservative solutions permitted refrigerated storage of red blood cells. However, the convenience of having red blood cell inventories was accompanied by a disadvantage. Red cells undergo numerous physical and metabolic changes during cold storage, the "storage lesion(s)". Whereas controlled clinical trials have not confirmed the clinical importance of such changes, ethical and operational issues have prevented careful study of the oldest stored red blood cells. Suggestions of toxicity from meta-analyses motivated us to develop pre-clinical canine models to compare the freshest vs the oldest red blood cells...
March 2017: Blood Transfusion, Trasfusione del Sangue
https://www.readbyqxmd.com/read/28260981/measurement-of-the-formula-see-text-and-formula-see-text-production-cross-sections-in-multilepton-final-states-using-3-2-fb-formula-see-text-of-formula-see-text-collisions-at-formula-see-text-13-tev-with-the-atlas-detector
#18
M Aaboud, G Aad, B Abbott, J Abdallah, O Abdinov, B Abeloos, R Aben, O S AbouZeid, N L Abraham, H Abramowicz, H Abreu, R Abreu, Y Abulaiti, B S Acharya, L Adamczyk, D L Adams, J Adelman, S Adomeit, T Adye, A A Affolder, T Agatonovic-Jovin, J Agricola, J A Aguilar-Saavedra, S P Ahlen, F Ahmadov, G Aielli, H Akerstedt, T P A Åkesson, A V Akimov, G L Alberghi, J Albert, S Albrand, M J Alconada Verzini, M Aleksa, I N Aleksandrov, C Alexa, G Alexander, T Alexopoulos, M Alhroob, B Ali, M Aliev, G Alimonti, J Alison, S P Alkire, B M M Allbrooke, B W Allen, P P Allport, A Aloisio, A Alonso, F Alonso, C Alpigiani, M Alstaty, B Alvarez Gonzalez, D Álvarez Piqueras, M G Alviggi, B T Amadio, K Amako, Y Amaral Coutinho, C Amelung, D Amidei, S P Amor Dos Santos, A Amorim, S Amoroso, G Amundsen, C Anastopoulos, L S Ancu, N Andari, T Andeen, C F Anders, G Anders, J K Anders, K J Anderson, A Andreazza, V Andrei, S Angelidakis, I Angelozzi, P Anger, A Angerami, F Anghinolfi, A V Anisenkov, N Anjos, A Annovi, C Antel, M Antonelli, A Antonov, F Anulli, M Aoki, L Aperio Bella, G Arabidze, Y Arai, J P Araque, A T H Arce, F A Arduh, J-F Arguin, S Argyropoulos, M Arik, A J Armbruster, L J Armitage, O Arnaez, H Arnold, M Arratia, O Arslan, A Artamonov, G Artoni, S Artz, S Asai, N Asbah, A Ashkenazi, B Åsman, L Asquith, K Assamagan, R Astalos, M Atkinson, N B Atlay, K Augsten, G Avolio, B Axen, M K Ayoub, G Azuelos, M A Baak, A E Baas, M J Baca, H Bachacou, K Bachas, M Backes, M Backhaus, P Bagiacchi, P Bagnaia, Y Bai, J T Baines, O K Baker, E M Baldin, P Balek, T Balestri, F Balli, W K Balunas, E Banas, Sw Banerjee, A A E Bannoura, L Barak, E L Barberio, D Barberis, M Barbero, T Barillari, T Barklow, N Barlow, S L Barnes, B M Barnett, R M Barnett, Z Barnovska-Blenessy, A Baroncelli, G Barone, A J Barr, L Barranco Navarro, F Barreiro, J Barreiro Guimarães da Costa, R Bartoldus, A E Barton, P Bartos, A Basalaev, A Bassalat, R L Bates, S J Batista, J R Batley, M Battaglia, M Bauce, F Bauer, H S Bawa, J B Beacham, M D Beattie, T Beau, P H Beauchemin, P Bechtle, H P Beck, K Becker, M Becker, M Beckingham, C Becot, A J Beddall, A Beddall, V A Bednyakov, M Bedognetti, C P Bee, L J Beemster, T A Beermann, M Begel, J K Behr, C Belanger-Champagne, A S Bell, G Bella, L Bellagamba, A Bellerive, M Bellomo, K Belotskiy, O Beltramello, N L Belyaev, O Benary, D Benchekroun, M Bender, K Bendtz, N Benekos, Y Benhammou, E Benhar Noccioli, J Benitez, D P Benjamin, J R Bensinger, S Bentvelsen, L Beresford, M Beretta, D Berge, E Bergeaas Kuutmann, N Berger, J Beringer, S Berlendis, N R Bernard, C Bernius, F U Bernlochner, T Berry, P Berta, C Bertella, G Bertoli, F Bertolucci, I A Bertram, C Bertsche, D Bertsche, G J Besjes, O Bessidskaia Bylund, M Bessner, N Besson, C Betancourt, S Bethke, A J Bevan, W Bhimji, R M Bianchi, L Bianchini, M Bianco, O Biebel, D Biedermann, R Bielski, N V Biesuz, M Biglietti, J Bilbao De Mendizabal, H Bilokon, M Bindi, S Binet, A Bingul, C Bini, S Biondi, D M Bjergaard, C W Black, J E Black, K M Black, D Blackburn, R E Blair, J-B Blanchard, J E Blanco, T Blazek, I Bloch, C Blocker, W Blum, U Blumenschein, S Blunier, G J Bobbink, V S Bobrovnikov, S S Bocchetta, A Bocci, C Bock, M Boehler, D Boerner, J A Bogaerts, D Bogavac, A G Bogdanchikov, C Bohm, V Boisvert, P Bokan, T Bold, A S Boldyrev, M Bomben, M Bona, M Boonekamp, A Borisov, G Borissov, J Bortfeldt, D Bortoletto, V Bortolotto, K Bos, D Boscherini, M Bosman, J D Bossio Sola, J Boudreau, J Bouffard, E V Bouhova-Thacker, D Boumediene, C Bourdarios, S K Boutle, A Boveia, J Boyd, I R Boyko, J Bracinik, A Brandt, G Brandt, O Brandt, U Bratzler, B Brau, J E Brau, H M Braun, W D Breaden Madden, K Brendlinger, A J Brennan, L Brenner, R Brenner, S Bressler, T M Bristow, D Britton, D Britzger, F M Brochu, I Brock, R Brock, G Brooijmans, T Brooks, W K Brooks, J Brosamer, E Brost, J H Broughton, P A Bruckman de Renstrom, D Bruncko, R Bruneliere, A Bruni, G Bruni, L S Bruni, B H Brunt, M Bruschi, N Bruscino, P Bryant, L Bryngemark, T Buanes, Q Buat, P Buchholz, A G Buckley, I A Budagov, F Buehrer, M K Bugge, O Bulekov, D Bullock, H Burckhart, S Burdin, C D Burgard, B Burghgrave, K Burka, S Burke, I Burmeister, J T P Burr, E Busato, D Büscher, V Büscher, P Bussey, J M Butler, C M Buttar, J M Butterworth, P Butti, W Buttinger, A Buzatu, A R Buzykaev, S Cabrera Urbán, D Caforio, V M Cairo, O Cakir, N Calace, P Calafiura, A Calandri, G Calderini, P Calfayan, L P Caloba, S Calvente Lopez, D Calvet, S Calvet, T P Calvet, R Camacho Toro, S Camarda, P Camarri, D Cameron, R Caminal Armadans, C Camincher, S Campana, M Campanelli, A Camplani, A Campoverde, V Canale, A Canepa, M Cano Bret, J Cantero, R Cantrill, T Cao, M D M Capeans Garrido, I Caprini, M Caprini, M Capua, R Caputo, R M Carbone, R Cardarelli, F Cardillo, I Carli, T Carli, G Carlino, L Carminati, S Caron, E Carquin, G D Carrillo-Montoya, J R Carter, J Carvalho, D Casadei, M P Casado, M Casolino, D W Casper, E Castaneda-Miranda, R Castelijn, A Castelli, V Castillo Gimenez, N F Castro, A Catinaccio, J R Catmore, A Cattai, J Caudron, V Cavaliere, E Cavallaro, D Cavalli, M Cavalli-Sforza, V Cavasinni, F Ceradini, L Cerda Alberich, B C Cerio, A S Cerqueira, A Cerri, L Cerrito, F Cerutti, M Cerv, A Cervelli, S A Cetin, A Chafaq, D Chakraborty, S K Chan, Y L Chan, P Chang, J D Chapman, D G Charlton, A Chatterjee, C C Chau, C A Chavez Barajas, S Che, S Cheatham, A Chegwidden, S Chekanov, S V Chekulaev, G A Chelkov, M A Chelstowska, C Chen, H Chen, K Chen, S Chen, S Chen, X Chen, Y Chen, H C Cheng, H J Cheng, Y Cheng, A Cheplakov, E Cheremushkina, R Cherkaoui El Moursli, V Chernyatin, E Cheu, L Chevalier, V Chiarella, G Chiarelli, G Chiodini, A S Chisholm, A Chitan, M V Chizhov, K Choi, A R Chomont, S Chouridou, B K B Chow, V Christodoulou, D Chromek-Burckhart, J Chudoba, A J Chuinard, J J Chwastowski, L Chytka, G Ciapetti, A K Ciftci, D Cinca, V Cindro, I A Cioara, C Ciocca, A Ciocio, F Cirotto, Z H Citron, M Citterio, M Ciubancan, A Clark, B L Clark, M R Clark, P J Clark, R N Clarke, C Clement, Y Coadou, M Cobal, A Coccaro, J Cochran, L Coffey, L Colasurdo, B Cole, A P Colijn, J Collot, T Colombo, G Compostella, P Conde Muiño, E Coniavitis, S H Connell, I A Connelly, V Consorti, S Constantinescu, G Conti, F Conventi, M Cooke, B D Cooper, A M Cooper-Sarkar, K J R Cormier, T Cornelissen, M Corradi, F Corriveau, A Corso-Radu, A Cortes-Gonzalez, G Cortiana, G Costa, M J Costa, D Costanzo, G Cottin, G Cowan, B E Cox, K Cranmer, S J Crawley, G Cree, S Crépé-Renaudin, F Crescioli, W A Cribbs, M Crispin Ortuzar, M Cristinziani, V Croft, G Crosetti, T Cuhadar Donszelmann, J Cummings, M Curatolo, J Cúth, C Cuthbert, H Czirr, P Czodrowski, G D'amen, S D'Auria, M D'Onofrio, M J Da Cunha Sargedas De Sousa, C Da Via, W Dabrowski, T Dado, T Dai, O Dale, F Dallaire, C Dallapiccola, M Dam, J R Dandoy, N P Dang, A C Daniells, N S Dann, M Danninger, M Dano Hoffmann, V Dao, G Darbo, S Darmora, J Dassoulas, A Dattagupta, W Davey, C David, T Davidek, M Davies, P Davison, E Dawe, I Dawson, R K Daya-Ishmukhametova, K De, R de Asmundis, A De Benedetti, S De Castro, S De Cecco, N De Groot, P de Jong, H De la Torre, F De Lorenzi, A De Maria, D De Pedis, A De Salvo, U De Sanctis, A De Santo, J B De Vivie De Regie, W J Dearnaley, R Debbe, C Debenedetti, D V Dedovich, N Dehghanian, I Deigaard, M Del Gaudio, J Del Peso, T Del Prete, D Delgove, F Deliot, C M Delitzsch, M Deliyergiyev, A Dell'Acqua, L Dell'Asta, M Dell'Orso, M Della Pietra, D Della Volpe, M Delmastro, P A Delsart, D A DeMarco, S Demers, M Demichev, A Demilly, S P Denisov, D Denysiuk, D Derendarz, J E Derkaoui, F Derue, P Dervan, K Desch, C Deterre, K Dette, P O Deviveiros, A Dewhurst, S Dhaliwal, A Di Ciaccio, L Di Ciaccio, W K Di Clemente, C Di Donato, A Di Girolamo, B Di Girolamo, B Di Micco, R Di Nardo, A Di Simone, R Di Sipio, D Di Valentino, C Diaconu, M Diamond, F A Dias, M A Diaz, E B Diehl, J Dietrich, S Diglio, A Dimitrievska, J Dingfelder, P Dita, S Dita, F Dittus, F Djama, T Djobava, J I Djuvsland, M A B do Vale, D Dobos, M Dobre, C Doglioni, T Dohmae, J Dolejsi, Z Dolezal, B A Dolgoshein, M Donadelli, S Donati, P Dondero, J Donini, J Dopke, A Doria, M T Dova, A T Doyle, E Drechsler, M Dris, Y Du, J Duarte-Campderros, E Duchovni, G Duckeck, O A Ducu, D Duda, A Dudarev, E M Duffield, L Duflot, L Duguid, M Dührssen, M Dumancic, M Dunford, H Duran Yildiz, M Düren, A Durglishvili, D Duschinger, B Dutta, M Dyndal, C Eckardt, K M Ecker, R C Edgar, N C Edwards, T Eifert, G Eigen, K Einsweiler, T Ekelof, M El Kacimi, V Ellajosyula, M Ellert, S Elles, F Ellinghaus, A A Elliot, N Ellis, J Elmsheuser, M Elsing, D Emeliyanov, Y Enari, O C Endner, M Endo, J S Ennis, J Erdmann, A Ereditato, G Ernis, J Ernst, M Ernst, S Errede, E Ertel, M Escalier, H Esch, C Escobar, B Esposito, A I Etienvre, E Etzion, H Evans, A Ezhilov, F Fabbri, L Fabbri, G Facini, R M Fakhrutdinov, S Falciano, R J Falla, J Faltova, Y 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Yoshida, K Yoshihara, C Young, C J S Young, S Youssef, D R Yu, J Yu, J M Yu, J Yu, L Yuan, S P Y Yuen, I Yusuff, B Zabinski, R Zaidan, A M Zaitsev, N Zakharchuk, J Zalieckas, A Zaman, S Zambito, L Zanello, D Zanzi, C Zeitnitz, M Zeman, A Zemla, J C Zeng, Q Zeng, K Zengel, O Zenin, T Ženiš, D Zerwas, D Zhang, F Zhang, G Zhang, H Zhang, J Zhang, L Zhang, R Zhang, R Zhang, X Zhang, Z Zhang, X Zhao, Y Zhao, Z Zhao, A Zhemchugov, J Zhong, B Zhou, C Zhou, L Zhou, L Zhou, M Zhou, N Zhou, C G Zhu, H Zhu, J Zhu, Y Zhu, X Zhuang, K Zhukov, A Zibell, D Zieminska, N I Zimine, C Zimmermann, S Zimmermann, Z Zinonos, M Zinser, M Ziolkowski, L Živković, G Zobernig, A Zoccoli, M Zur Nedden, L Zwalinski
A measurement of the [Formula: see text] and [Formula: see text] production cross sections in final states with either two same-charge muons, or three or four leptons (electrons or muons) is presented. The analysis uses a data sample of proton-proton collisions at [Formula: see text] TeV recorded with the ATLAS detector at the Large Hadron Collider in 2015, corresponding to a total integrated luminosity of 3.2 fb[Formula: see text]. The inclusive cross sections are extracted using likelihood fits to signal and control regions, resulting in [Formula: see text] pb and [Formula: see text] pb, in agreement with the Standard Model predictions...
2017: European Physical Journal. C, Particles and Fields
https://www.readbyqxmd.com/read/28260979/a-measurement-of-the-calorimeter-response-to-single-hadrons-and-determination-of-the-jet-energy-scale-uncertainty-using-lhc-run-1-pp-collision-data-with-the-atlas-detector
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Yu, J M Yu, J Yu, L Yuan, S P Y Yuen, I Yusuff, B Zabinski, R Zaidan, A M Zaitsev, N Zakharchuk, J Zalieckas, A Zaman, S Zambito, L Zanello, D Zanzi, C Zeitnitz, M Zeman, A Zemla, J C Zeng, Q Zeng, K Zengel, O Zenin, T Ženiš, D Zerwas, D Zhang, F Zhang, G Zhang, H Zhang, J Zhang, L Zhang, R Zhang, R Zhang, X Zhang, Z Zhang, X Zhao, Y Zhao, Z Zhao, A Zhemchugov, J Zhong, B Zhou, C Zhou, L Zhou, L Zhou, M Zhou, N Zhou, C G Zhu, H Zhu, J Zhu, Y Zhu, X Zhuang, K Zhukov, A Zibell, D Zieminska, N I Zimine, C Zimmermann, S Zimmermann, Z Zinonos, M Zinser, M Ziolkowski, L Živković, G Zobernig, A Zoccoli, M Zur Nedden, L Zwalinski
A measurement of the calorimeter response to isolated charged hadrons in the ATLAS detector at the LHC is presented. This measurement is performed with 3.2 nb[Formula: see text] of proton-proton collision data at [Formula: see text] [Formula: see text] from 2010 and 0.1 nb[Formula: see text] of data at [Formula: see text] [Formula: see text] from 2012. A number of aspects of the calorimeter response to isolated hadrons are explored. After accounting for energy deposited by neutral particles, there is a 5% discrepancy in the modelling, using various sets of Geant4 hadronic physics models, of the calorimeter response to isolated charged hadrons in the central calorimeter region...
2017: European Physical Journal. C, Particles and Fields
https://www.readbyqxmd.com/read/28260978/measurements-of-the-formula-see-text-production-cross-section-in-lepton-jets-final-states-in-pp-collisions-at-8-formula-see-text-and-ratio-of-8-to-7%C3%A2-formula-see-text-cross-sections
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Eshaq, T Ferbel, M Galanti, A Garcia-Bellido, J Han, A Harel, O Hindrichs, A Khukhunaishvili, G Petrillo, P Tan, M Verzetti, S Arora, A Barker, J P Chou, C Contreras-Campana, E Contreras-Campana, D Duggan, D Ferencek, Y Gershtein, R Gray, E Halkiadakis, D Hidas, E Hughes, S Kaplan, R Kunnawalkam Elayavalli, A Lath, K Nash, S Panwalkar, M Park, S Salur, S Schnetzer, D Sheffield, S Somalwar, R Stone, S Thomas, P Thomassen, M Walker, M Foerster, G Riley, K Rose, S Spanier, A York, O Bouhali, A Castaneda Hernandez, M Dalchenko, M De Mattia, A Delgado, S Dildick, R Eusebi, J Gilmore, T Kamon, V Krutelyov, R Mueller, I Osipenkov, Y Pakhotin, R Patel, A Perloff, A Rose, A Safonov, A Tatarinov, K A Ulmer, N Akchurin, C Cowden, J Damgov, C Dragoiu, P R Dudero, J Faulkner, S Kunori, K Lamichhane, S W Lee, T Libeiro, S Undleeb, I Volobouev, E Appelt, A G Delannoy, S Greene, A Gurrola, R Janjam, W Johns, C Maguire, Y Mao, A Melo, H Ni, P Sheldon, B Snook, S Tuo, J Velkovska, Q Xu, M W Arenton, B Cox, B Francis, J Goodell, R Hirosky, A Ledovskoy, H Li, C Lin, C Neu, T Sinthuprasith, X Sun, Y Wang, E Wolfe, J Wood, F Xia, C Clarke, R Harr, P E Karchin, C Kottachchi Kankanamge Don, P Lamichhane, J Sturdy, D A Belknap, D Carlsmith, M Cepeda, S Dasu, L Dodd, S Duric, B Gomber, M Grothe, R Hall-Wilton, M Herndon, A Hervé, P Klabbers, A Lanaro, A Levine, K Long, R Loveless, A Mohapatra, I Ojalvo, T Perry, G A Pierro, G Polese, T Ruggles, T Sarangi, A Savin, A Sharma, N Smith, W H Smith, D Taylor, N Woods
A measurement of the top quark pair production ([Formula: see text]) cross section in proton-proton collisions at the centre-of-mass energy of 8[Formula: see text] is presented using data collected with the CMS detector at the LHC, corresponding to an integrated luminosity of 19.6[Formula: see text]. This analysis is performed in the [Formula: see text] decay channels with one isolated, high transverse momentum electron or muon and at least four jets, at least one of which is required to be identified as originating from hadronization of a b quark...
2017: European Physical Journal. C, Particles and Fields
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