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"Neurological recovery"

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https://www.readbyqxmd.com/read/29212639/advanced-practice-registered-nurses-on-therapeutic-hypothermia-response-teams
#1
Jason Wannemacher, Dana Tschannen, Kim Biery, Cynthia Arslanian-Engoren
BACKGROUND: Therapeutic hypothermia can improve neurological recovery after cardiac arrest when implemented quickly. OBJECTIVE: To determine whether outcomes are improved among patients undergoing therapeutic hypothermia by adding advanced practice registered nurses to a therapeutic hypothermia response team. METHODS: A pilot quality improvement project was conducted in a Midwest community teaching hospital using a retrospective chart review of all adult patients undergoing therapeutic hypothermia before and after the addition of advanced practice registered nurses to the therapeutic hypothermia response team...
2017: AACN Advanced Critical Care
https://www.readbyqxmd.com/read/29208449/surgical-treatment-of-thoracic-spinal-tuberculosis-a-multi-center-retrospective-study
#2
Wenjie Wu, Jingtong Lyu, Xun Liu, Fei Luo, TianYong Hou, Qiang Zhou, Zhilin Li, Yuan Chen, Li Tao Li, Yonghong Zheng, Gaoju Wang, Jianzhong Xu, Zehua Zhang
OBJECTIVE: The aim present multicenter retrospective study is to assess safety and effectiveness of different surgery strategy in thoracic tuberculosis, and to provide a reference for surgical treatment of thoracic tuberculosis. MATERIALS AND METHODS: This study reviewed 394 patients with thoracic tuberculosis who were treated in six institution between January 2000 and January 2015. There were 208 males and 186 females with average ages of 34.92±13.14 years (range 5-76 years)...
December 2, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29201856/complete-reversal-of-diffusion-restriction-after-treatment-of-traumatic-carotid-cavernous-fistula
#3
Jeong Hyun Shim, Inbo Han
A 15-year-old man presented with stupor following a motorcycle traffic accident. The patient was diagnosed with a traumatic left carotid cavernous fistula (CCF) with pseudoaneurysm of the left internal carotid artery. Brain magnetic resonance imaging (MRI) showed transiently restricted diffusion in the left centrum semiovale white matter and lower temporo-occipital area extending to the splenium of the corpus callosum, with high signal intensity on diffusion-weighted imaging. On the 35th day of admission, the patient had complete neurological recovery and a follow-up brain MRI revealed complete resolution of the lesions in the left centrum semiovale and splenium of the corpus callosum...
October 2017: Korean Journal of Neurotrauma
https://www.readbyqxmd.com/read/29200424/arm-rehabilitation-in-post-stroke-subjects-a-randomized-controlled-trial-on-the-efficacy-of-myoelectrically-driven-fes-applied-in-a-task-oriented-approach
#4
Johanna Jonsdottir, Rune Thorsen, Irene Aprile, Silvia Galeri, Giovanna Spannocchi, Ettore Beghi, Elisa Bianchi, Angelo Montesano, Maurizio Ferrarin
PURPOSE: Motor recovery of persons after stroke may be enhanced by a novel approach where residual muscle activity is facilitated by patient-controlled electrical muscle activation. Myoelectric activity from hemiparetic muscles is then used for continuous control of functional electrical stimulation (MeCFES) of same or synergic muscles to promote restoration of movements during task-oriented therapy (TOT). Use of MeCFES during TOT may help to obtain a larger functional and neurological recovery than otherwise possible...
2017: PloS One
https://www.readbyqxmd.com/read/29191060/endoscopic-endonasal-resection-of-a-medullary-cavernoma-a-novel-case
#5
Puya Alikhani, Sananthan Sivakanthan, Ramsey Ashour, Mark Tabor, Harry van Loveren, Siviero Agazzi
Brainstem cavernomas can present very challenging operative problems. Endoscopic endonasal approaches to these lesions in the mesencephalon and pons have been described. In this article the authors present the first case of a medullary cavernoma resected by an endoscopic transclival approach. A 26 year-old woman with a 1.5 cm medullary cavernoma presented with imbalance, swallowing difficulty, and right hemibody weakness. She was taken to the operating room for endoscopic endonasal transclival resection. Her pre-existing neurologic deficits worsened initially after surgery, but at three-month follow-up she had made a full neurologic recovery...
November 30, 2017: British Journal of Neurosurgery
https://www.readbyqxmd.com/read/29188763/prothrombotic-state-in-a-patient-with-acute-liver-failure-the-question-of-anticoagulation
#6
Ecaterina Scărlă Tescu, Dana Rodica Tomescu
A 35-year-old male with acute liver failure due to acute hepatitis B virus infection was admitted to the intensive care unit with significant hepatocellular injury, cholestasis, abnormal standard coagulation tests, normal rotational thromboelastometry indices, and without signs of bleeding. He underwent emergency liver transplantation without requiring blood product transfusions or procoagulant treatments. The postoperative course was complicated by deep vein thrombosis and impending hepatic artery thrombosis treated with unfractionated heparin, aspirin, and intravenous prostacyclin...
November 1, 2017: Seminars in Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/29183314/does-clinical-supervision-of-healthcare-professionals-improve-effectiveness-of-care-and-patient-experience-a-systematic-review
#7
David A Snowdon, Sandra G Leggat, Nicholas F Taylor
BACKGROUND: To ensure quality of care delivery clinical supervision has been implemented in health services. While clinical supervision of health professionals has been shown to improve patient safety, its effect on other dimensions of quality of care is unknown. The purpose of this systematic review is to determine whether clinical supervision of health professionals improves effectiveness of care and patient experience. METHODS: Databases MEDLINE, PsychINFO, CINAHL, EMBASE and AMED were searched from earliest date available...
November 28, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/29181341/odontoideum-bone-revealed-by-c1-c2-dislocation-of-the-cervical-spine-during-a-diving-accident
#8
Lassaad Hassini, Mohamed Ali Khalifa, Zeineb Alaya, Mohamed Laaziz Ben Ayeche, Walid Osman, Mourad Mtaoumi
Introduction: Odontoideum bone or the mobile odontoid process is one of the rarest malformations of the cervico-occipital hinge. It exposes to the atlo-axial instability and to the risk of bulbo-medullary compression threatening then the vital and functional prognosis. We report the case of a 16-year-old patient who was the victim of a raod accident resulting in acervical spine injury. Radiological investigation found an odontoideum bone malformation associated with C1C2 dislocation. Case Report: A 16-year-old patient with no medical history had a road accident...
July 2017: Journal of Orthopaedic Case Reports
https://www.readbyqxmd.com/read/29181199/the-effects-of-aerobic-exercise-on-the-recovery-of-walking-ability-and-neuroplasticity-in-people-with-multiple-sclerosis-a-systematic-review-of-animal-and-clinical-studies
#9
REVIEW
Augustine Joshua Devasahayam, Matthew Bruce Downer, Michelle Ploughman
Introduction: Walking is of high priority for people with multiple sclerosis (PwMS). It remains unclear whether aerobic exercise can improve walking ability and upregulate neurotrophins. This review aims to consolidate evidence to develop optimal aerobic training parameters to enhance walking outcomes and neuroplasticity in PwMS. Methods: Clinical studies examining aerobic exercise for ≥3 weeks, having outcomes on walking with or without neurotrophic markers, were included...
2017: Multiple Sclerosis International
https://www.readbyqxmd.com/read/29177620/revisiting-traumatic-cardiac-arrest-should-cpr-be-initiated
#10
Katie L Konesky, Weidun Alan Guo
OBJECTIVES: Traumatic cardiac arrest (TCA) represents a unique problem, and poses difficult challenges in the care of trauma patients. Although the literature has suggested that attempted resuscitation from TCA in trauma is futile and consumptive of medical and human resources, studies have recently demonstrated that the outcome of TCA is comparable cardiac arrest secondary to non-traumatic events. The objective of this study was to determine the incidence, predictors, and outcomes following TCA...
November 25, 2017: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
https://www.readbyqxmd.com/read/29176798/the-scavenging-chemokine-receptor-ackr2-has-a-significant-impact-on-acute-mortality-rate-and-early-lesion-development-after-traumatic-brain-injury
#11
Thomas M Woodcock, Tony Frugier, Tan Thanh Nguyen, Bridgette Deanne Semple, Nicole Bye, Matteo Massara, Benedetta Savino, Roberta Besio, Cristina Sobacchi, Massimo Locati, Maria Cristina Morganti-Kossmann
The atypical chemokine receptor ACKR2 promotes resolution of acute inflammation by operating as a scavenger receptor for inflammatory CC chemokines in several experimental models of inflammatory disorders, however its role in the brain remains unclear. Based on our previous reports of increased expression of inflammatory chemokines and their corresponding receptors following traumatic brain injury (TBI), we hypothesised that ACKR2 modulates neuroinflammation following brain trauma and that its deletion exacerbates cellular inflammation and chemokine production...
2017: PloS One
https://www.readbyqxmd.com/read/29173438/importance-of-sagittal-alignment-of-the-cervical-spine-in-the-management-of-degenerative-cervical-myelopathy
#12
REVIEW
Thomas J Buell, Avery L Buchholz, John C Quinn, Christopher I Shaffrey, Justin S Smith
Cervical spine sagittal malalignment correlates with worse symptoms and outcomes in patients with degenerative cervical myelopathy (DCM), and should influence surgical management. An anterior versus posterior surgical approach may not significantly change outcomes in patients with preoperative lordosis; however, most studies suggest improved neurologic recovery among kyphotic patients after adequate correction of local sagittal alignment through an anterior or combined anterior-posterior approach. There are no comprehensive guidelines for DCM management in the setting of cervical malalignment; therefore, surgical management should be tailored to individual patients and decisions made at the discretion of treating surgeons with attention to basic principles...
January 2018: Neurosurgery Clinics of North America
https://www.readbyqxmd.com/read/29173423/significant-predictors-of-outcome-following-surgery-for-the-treatment-of-degenerative-cervical-myelopathy-a-systematic-review-of-the-literature
#13
REVIEW
Lindsay Tetreault, Lisa M Palubiski, Michael Kryshtalskyj, Randy K Idler, Allan R Martin, Mario Ganau, Jefferson R Wilson, Mark Kotter, Michael G Fehlings
This systematic review aims to summarize important clinical predictors of outcomes in patients undergoing surgery for the treatment of degenerative cervical myelopathy. Based on the results of this article, patients with a longer duration of symptoms and more severe myelopathy are likely to have worse surgical outcomes. With respect to age, several studies have indicated that elderly patients are less likely to translate neurologic recovery into functional improvements. However, many other studies have failed to identify a significant association between age and outcomes...
January 2018: Neurosurgery Clinics of North America
https://www.readbyqxmd.com/read/29164038/timing-of-decompression-in-patients-with-acute-spinal-cord-injury-a-systematic-review
#14
REVIEW
Jefferson R Wilson, Lindsay A Tetreault, Brian K Kwon, Paul M Arnold, Thomas E Mroz, Christopher Shaffrey, James S Harrop, Jens R Chapman, Steve Casha, Andrea C Skelly, Haley K Holmer, Erika D Brodt, Michael G Fehlings
Study Design: Systematic review. Objective: To conduct a systematic review and synthesis of the literature to assess the comparative effectiveness, safety, and cost-effectiveness of early (≤24 hours) versus late decompression (>24 hours) in adults with acute spinal cord injury (SCI). Methods: A systematic search was conducted of Medline, EMBASE, the Cochrane Collaboration Library, and Google Scholar to identify studies published through November 6, 2014...
September 2017: Global Spine Journal
https://www.readbyqxmd.com/read/29164022/impact-of-baseline-magnetic-resonance-imaging-on-neurologic-functional-and-safety-outcomes-in-patients-with-acute-traumatic-spinal-cord-injury
#15
REVIEW
Shekar Kurpad, Allan R Martin, Lindsay A Tetreault, Dena J Fischer, Andrea C Skelly, David Mikulis, Adam Flanders, Bizhan Aarabi, Thomas E Mroz, Eve C Tsai, Michael G Fehlings
Study Design: Systematic review. Objective: To perform a systematic review to evaluate the utility of magnetic resonance imaging (MRI) in patients with acute spinal cord injury (SCI). Methods: An electronic search of Medline, EMBASE, the Cochrane Collaboration Library, and Google Scholar was conducted for literature published through May 12, 2015, to answer key questions associated with the use of MRI in patients with acute SCI. Results: The literature search yielded 796 potentially relevant citations, 8 of which were included in this review...
September 2017: Global Spine Journal
https://www.readbyqxmd.com/read/29164020/efficacy-and-safety-of-methylprednisolone-sodium-succinate-in-acute-spinal-cord-injury-a-systematic-review
#16
REVIEW
Michael G Fehlings, Jefferson R Wilson, James S Harrop, Brian K Kwon, Lindsay A Tetreault, Paul M Arnold, Jeffrey M Singh, Gregory Hawryluk, Joseph R Dettori
Study Design: Systematic review and meta-analysis. Objective: The objective of this study was to conduct a systematic review to assess the comparative effectiveness and safety of high-dose methylprednisolone sodium succinate (MPSS) versus no pharmacological treatment in patients with traumatic spinal cord injury (SCI). Methods: A systematic search was performed in PubMed and the Cochrane Collaboration Library for literature published between January 1956 and June 17, 2015...
September 2017: Global Spine Journal
https://www.readbyqxmd.com/read/29152223/stage-1-registered-report-effect-of-deficient-phagocytosis-on-neuronal-survival-and-neurological-outcome-after-temporary-middle-cerebral-artery-occlusion-tmcao
#17
Julius V Emmrich, Jonas J Neher, Philipp Boehm-Sturm, Matthias Endres, Ulrich Dirnagl, Christoph Harms
Stroke is a major cause of death and disability worldwide. In addition to neuronal death resulting directly from energy depletion due to lack of blood supply, inflammation and microglial activation following ischemic brain injury has been increasingly recognized to be a key contributor to the pathophysiology of cerebrovascular disease. However, our understanding of the cross talk between the ischemic brain and the immune system is limited. Recently, we demonstrated that following focal ischemia, death of mature viable neurons can be executed through phagocytosis by microglial cells or recruited macrophages, i...
2017: F1000Research
https://www.readbyqxmd.com/read/29146880/optogenetic-inhibition-of-striatal-gabaergic-neuronal-activity-improves-outcomes-after-ischemic-brain-injury
#18
Lu Jiang, Wanlu Li, Muyassar Mamtilahun, Yaying Song, Yuanyuan Ma, Meijie Qu, Yifan Lu, Xiaosong He, Jieyu Zheng, Zongjie Fu, Zhijun Zhang, Guo-Yuan Yang, Yongting Wang
BACKGROUND AND PURPOSE: Striatal GABAergic neuron is known as a key regulator in adult neurogenesis. However, the specific role of striatal GABAergic neuronal activity in the promotion of neurological recovery after ischemic stroke remains unknown. Here, we used optogenetic approach to investigate these effects and mechanism. METHODS: Laser stimulation was delivered via an implanted optical fiber to inhibit or activate the striatal GABAergic neurons in Gad2-Arch-GFP or Gad2-ChR2-tdTomato mice (n=80) 1 week after 60-minute transient middle cerebral artery occlusion...
November 16, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/29137416/analysis-of-clinical-and-neurological-outcomes-in-patients-with-cauda-equina-syndrome-caused-by-acute-lumbar-disc-herniation-a-retrospective-prospective-study
#19
Si-Dong Yang, Feng Zhang, Wen-Yuan Ding
Objectives: In this research we analyzed the results of surgical treatment of cauda equina syndrome (CES) caused by acute lumbar disc herniation. We emphasize the early treatment for good neurological recovery. Methods: A retrospective-prospective, non randomized, clinical study was performed between Jan 2010 and Dec 2014. We retrospectively collected medical records of 18 patients who suffered from CES due to acute lumbar disc herniation and followed up them regularly...
October 13, 2017: Oncotarget
https://www.readbyqxmd.com/read/29136737/-research-progress-on-early-diagnosis-reasonable-prevention-and-treatment-of-symptomatic-spinal-epidural-hematoma-following-spinal-surgery
#20
X W Ye, S S Liu, P H Zeng, B L Liu
Symptomatic spinal epidural hematoma (SSEH) following spinal surgery is rare but one of the serious complications. SSEH can leave devastating neurological consequences if missing the optimal timing for treatment. The early diagnosis of SSEH is critical to the neurologic recovery, and MRI examination can help to check the location and the scope of the hematoma and provide imaging information for surgical operation. The risk factors of SSEH can be divided into preoperative factors, intraoperative factors and postoperative factors...
November 1, 2017: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
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