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"Neurological recovery"

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https://www.readbyqxmd.com/read/29674994/a-cross-sectional-study-on-cerebral-hemodynamics-after-mild-traumatic-brain-injury-in-a-pediatric-population
#1
Corey M Thibeault, Samuel Thorpe, Michael J O'Brien, Nicolas Canac, Mina Ranjbaran, Ilyas Patanam, Artin Sarraf, James LeVangie, Fabien Scalzo, Seth J Wilk, Ramon Diaz-Arrastia, Robert B Hamilton
The microvasculature is prominently affected by traumatic brain injury (TBI), including mild TBI (concussion). Assessment of cerebral hemodynamics shows promise as biomarkers of TBI, and may help inform development of therapies aimed at promoting neurologic recovery. The objective of this study was to assess the evolution in cerebral hemodynamics observable with transcranial Doppler (TCD) ultrasound in subjects suffering from a concussion at different intervals during recovery. Pediatric subjects between the ages of 14 and 19 years clinically diagnosed with a concussion were observed at different points post-injury...
2018: Frontiers in Neurology
https://www.readbyqxmd.com/read/29666925/-which-patients-benefit-from-transport-with-ongoing-cardiopulmonary-resuscitation-retrospective-analysis-of-70-patients-with-refractory-preclinical-cardiac-arrest
#2
C Adler, C Paul, J Hinkelbein, G Michels, R Pfister, A Krings, A Lechleuthner, R Stangl
BACKGROUND: Mortality in patients with out-of-hospital cardiac arrest (OHCA) remains very high despite advances in resuscitation algorithms. Most of these patients die at the scene and do not reach hospital. It is currently the subject of discussion whether transport to hospital with ongoing cardiopulmonary resuscitation (CPR) improves survival and neurological outcome in patients with OHCA. OBJECTIVE: The aim of this study was to identify predictors of survival and good neurological outcome in patients after OHCA who were transported to hospital with ongoing CPR...
April 17, 2018: Der Anaesthesist
https://www.readbyqxmd.com/read/29666075/rogue-one-a-story-of-tophaceous-gout-in-the-spine
#3
Karthik Dwarki, Andy Dothard, Bryan Abadie, Matthew C Miles
A 26-year-old man with history of extensive tophaceous gout presented to the referring facility with decreased bilateral lower extremity sensation and motor function that began acutely 1 week prior to admission and had progressed to urinary incontinence. The patient was admitted to the intensive care unit due to concern for sepsis secondary to epidural abscess. The patient was started on empiric vancomycin and cefepime. Neurosurgery did not recommend acute neurosurgical intervention given the lack of a compressive lesion...
April 17, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29665733/natural-history-predictors-of-outcome-and-effects-of-treatment-in-thoracic-spinal-cord-injury-a-multicenter-cohort-study-from-the-north-american-clinical-trials-network
#4
Jefferson R Wilson, Blessing Jaja, Brian K Kwon, James Guest, James Shields Harrop, Bizhan Aarabi, Christopher Shaffrey, Jetan Badhiwala, Elizabeth Toups, Robert Grossman, Michael G Fehlings
The course, treatment response and recovery potential following acute traumatic spinal cord injury (SCI) have been shown to differ depending on the neurological level of injury. However, there are limited data focused on thoracic-level injuries. A cohort of 86 patients from the prospectively maintained North American Clinical Trials Network (NACTN) SCI registry were identified and studied to characterize the patterns of neurological recovery as well as to determine rates of acute hospital mortality and pulmonary complications...
April 18, 2018: Journal of Neurotrauma
https://www.readbyqxmd.com/read/29665155/defining-mechanisms-of-neural-plasticity-after-brainstem-ischemia-in-rats
#5
Jens Minnerup, Jan-Kolja Strecker, Lydia Wachsmuth, Maike Hoppen, Antje Schmidt, Dirk M Hermann, Heinz Wiendl, Sven Meuth, Cornelius Faber, Kai Diederich, Wolf Rüdiger Schäbitz
OBJECTIVE: Neurological recovery after stroke mainly depends on the location of the lesion. A substantial portion of strokes affects the brainstem. However, patterns of neural plasticity following brainstem ischemia are almost unknown. METHODS: Here, we established a rat brainstem ischemia model that resembles key features of the human disease and investigated mechanisms of neural plasticity including neurogenesis and axonal sprouting as well as secondary neurodegeneration...
April 17, 2018: Annals of Neurology
https://www.readbyqxmd.com/read/29663146/thoraco-lumbar-fractures-with-blunt-traumatic-aortic-injury-in-adult-patients-correlations-and-management
#6
Giorgio Santoro, Alessandro Ramieri, Vito Chiarella, Massimo Vigliotta, Maurizio Domenicucci
PURPOSE: Traumatic thoraco-lumbar spine fracture spine with a concomitant blunt aortic injury is uncommon but potentially a fatal association. Our aim was to clarify: morphology of spinal fractures related to vascular damages and vice versa, diagnostic procedures and decision-making process for the best treatment options for spine and vessels. METHODS: We enrolled 42 cases culled from the literature and five personal ones, reviewing in detail by AO Spine Classification, Society of Vascular Surgery classification and Abbreviated Injury Scale for neurological evaluation...
April 16, 2018: European Spine Journal
https://www.readbyqxmd.com/read/29663144/is-anterior-release-and-cervical-traction-necessary-for-the-treatment-of-irreducible-atlantoaxial-dislocation-a-systematic-review-and-meta-analysis
#7
REVIEW
Jian Guan, Zan Chen, Hao Wu, Qingyu Yao, Can Zhang, Tengfei Qi, Kai Wang, Wanru Duan, Jun Gao, Yongning Li, Fengzeng Jian
PURPOSE: To compare the clinical and radiographic outcomes of irreducible atlantoaxial dislocation (IAAD) treated with posterior fusion after anterior release and direct posterior reduction of the dislocation. METHODS: Online databases were searched for articles describing IAAD published from 1999 to 2015. Five studies (105 patients) described treatment with posterior fusion after periodontoid tissue release, and five studies (113 patients) described treatment with direct posterior reduction of the dislocation...
April 16, 2018: European Spine Journal
https://www.readbyqxmd.com/read/29629926/neuroprognostication-postcardiac-arrest-translating-probabilities-to-individuals
#8
Clifton W Callaway
PURPOSE OF REVIEW: Predicting neurological recovery in patients who are comatose after cardiac arrest is an important activity during postarrest care, and this prediction can affect survival. As no early test or clinical finding perfectly predicts potential for recovery, guidelines recommend using data from multiple examinations or tests to estimate patient prognosis. RECENT FINDINGS: Studies reported accuracy of initial clinical examination, progression of clinical examination, early (<24 h) brain imaging, electroencephalography (EEG), evoked potentials, later (>24 h) brain imaging, blood markers of brain injury, and cerebral oximetry for predicting good or poor outcome...
April 6, 2018: Current Opinion in Critical Care
https://www.readbyqxmd.com/read/29629684/hypertension-as-the-trigger-for-posterior-reversible-encephalopathy-syndrome-in-paediatric-renal-patients-an-important-diagnosis-that-should-not-be-missed
#9
J K Strong, K L Petersen, U Kala
BACKGROUND: Posterior reversible encephalopathy syndrome (PRES) is a reversible neurological condition presenting with seizures and visual disturbances and diagnosed on magnetic resonance imaging (MRI). Little is understood about its pathogenesis, particularly in children, but it is thought to be related to hypertension. OBJECTIVES: To review the presentation, diagnosis and outcome of PRES in paediatric renal patients at Chris Hani Baragwanath Academic Hospital, Johannesburg, South Africa, between 1 January 2000 and 31 January 2017 and compare these with published case reports to date...
March 28, 2018: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
https://www.readbyqxmd.com/read/29629233/large-central-lumbar-disc-herniation-causing-acute-cauda-equina-syndrome-with-loss-of-evoked-potentials-during-prone-positioning-for-surgery
#10
Adam Ammar, Reza Zarnegar, Reza Yassari, Merritt Kinon
Background: Few studies in the literature discuss operative positioning for lumbar surgery precipitating acute cauda equina syndromes (CES). Case Description: A 56-year-old male with a large L2-3-disc herniation was placed prone on a Jackson table. He immediately lost all motor and sensory evoked potentials. Signals returned to the baseline when surgery was aborted, and he was returned to the supine position. However, potentials were again lost when he was repositioned prone, following which the surgeons proceeded with surgical decompression with a good outcome...
2018: Surgical Neurology International
https://www.readbyqxmd.com/read/29626691/spinal-concussion-in-adults-transient-neuropraxia-of-spinal-cord-exposed-to-vertical-forces
#11
Ziya Asan
OBJECTIVE: The aim of the study is to discuss along with literature knowledge the post-traumatic clinical progression of cases with symptoms of transient spinal cord impact and cases of spinal concussion following the exposure of the vertebral column to vertical forces. MATERIALS AND METHODS: A total of 43 cases were diagnosed with spinal concussion. All of the cases were cases of fall from height where it was determined that the vertebral column had been exposed to the effects of vertical forces and the spinal cord had been affected under the effect of vertical forces...
April 4, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29625309/risk-factors-for-significant-intraoperative-blood-loss-during-unilateral-expansive-open-door-cervical-laminoplasty-for-cervical-compressive-myelopathy
#12
Yang Meng, Xiaofei Wang, Hua Chen, Ying Hong, Tingkui Wu, Beiyu Wang, Yuxiao Deng, Hao Liu
OBJECTIVE: Unilateral expansive open-door cervical laminoplasty is an effective and safe procedure for cervical compressive myelopathy, but occasionally is accompanied with significant intraoperative blood loss (SIBL). The aim of the present study was to elucidate the risk factors for SIBL in patients undergoing cervical laminoplasty for multilevel cervical compressive myelopathy, and to identify the effect of SIBL on neurological complication. METHODS: A total of 215 patients who received cervical laminoplasty between January 2010 and August 2016 were enrolled in the study...
April 3, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29619251/spinal-subdural-hematoma-and-ankylosing-spondylitis-case-report-and-review-of-literature
#13
Darian R Esfahani, Harsh P Shah, Mandana Behbahani, Gregory D Arnone, Ankit I Mehta
Introduction: Spinal subdural hematomas are rare, disabling hemorrhages. Ankylosing spondylitis (AS) is a relatively common inflammatory condition of the spine that can progress to a fragile, unstable fusion vulnerable to fracture. While spinal epidural hematomas have been described, subdural hematomas to date have not been reported in AS. In this report, we describe the unique case of a patient on warfarin with AS who developed a spinal subdural hematoma and fracture in the absence of trauma...
2018: Spinal Cord Series and Cases
https://www.readbyqxmd.com/read/29615517/the-nociceptin-receptor-inhibits-axonal-regeneration-and-recovery-from-spinal-cord-injury
#14
Yuichi Sekine, Chad S Siegel, Tomoko Sekine-Konno, William B J Cafferty, Stephen M Strittmatter
Axonal growth after traumatic spinal cord injury is limited by endogenous inhibitors, selective blockade of which promotes partial neurological recovery. The partial repair phenotypes suggest that compensatory pathways limit improvement. Gene expression profiles of mice deficient in Ngr1 , which encodes a receptor for myelin-associated inhibitors of axonal regeneration such as Nogo, revealed that trauma increased the mRNA expression of ORL1 , which encodes the receptor for the opioid-related peptide nociceptin...
April 3, 2018: Science Signaling
https://www.readbyqxmd.com/read/29614893/cerebral-artery-gas-embolism-following-navigational-bronchoscopy
#15
Keren Fogelfeld, Richie K Rana, Guy W Soo Hoo
INTRODUCTION: Cerebral artery gas embolism (CAGE) is a rare but serious adverse event with potentially devastating neurologic sequelae. Bronchoscopy is a frequently performed procedure but with only a few reported cases of CAGE. METHODS: We report the first documented case of CAGE associated with electromagnetic navigational bronchoscopy. RESULTS: A 61-year-old man with a left lower lobe nodule underwent electromagnetic navigational bronchoscopy...
January 1, 2018: Journal of Intensive Care Medicine
https://www.readbyqxmd.com/read/29614362/sciwora-in-adults-clinical-and-radiological-discordance
#16
Ziya Asan
OBJECTIVE: SCIWORA cases show different clinical prognostic courses independent of radiological findings. The fact that the cases could not be evaluated by a specific terminological standard has led to the emergence of the real SCIWORA definition. In this study, clinical progressions of 11 patients diagnosed with SCIWORA were analyzed, and terminological differences were discussed. MATERIALS AND METHODS: The clinical findings of 11 adults that were followed-up with a diagnosis of SCIWORA at the time of diagnosis and in the long term were analyzed according to the ASIA classification...
March 31, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29600414/metastatic-epidural-spinal-cord-compression-does-timing-of-surgery-influence-the-chance-of-neurological-recovery-an-observational-case-control-study
#17
Valerio Pipola, Silvia Terzi, Giuseppe Tedesco, Stefano Bandiera, Giovanni Barbanti Bròdano, Riccardo Ghermandi, Gisberto Evangelisti, Marco Girolami, Alessandro Gasbarrini
PURPOSE: Metastatic epidural spinal cord compression (MESCC) is radiologically defined as an epidural metastatic lesion causing the displacement of the spinal cord from its normal position in the vertebral canal. The purpose of this paper is the evaluation of the influence of timing of surgery on the chance of neurological recovery. METHODS: This is a retrospective observational case-control study performed on patients with MESCC from solid tumors surgically treated at our institute from January 2010 to December 2016...
March 30, 2018: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/29600211/unusual-presentation-of-spinal-gout-2-cases-report-and-literature-review
#18
Wesley Ng, Cheuk Hang Sin, Chong Hing Wong, Wing Fat Chiu, On Ming Chung
Introduction: Gouty spondyloarthropathy is generally believed to be uncommon. Together with the fact that it can mimic a variety of disease entities, it imposes significant diagnostic challenge in our clinical practice. In this article, we report two patients diagnosed with spinal gout, and both were initially suspected to have a pyogenic infection. Case Reports: The first patient, a 66-year-old man, was admitted for fever and a short history of bilateral upper limb weakness...
November 2017: Journal of Orthopaedic Case Reports
https://www.readbyqxmd.com/read/29582153/predictive-factors-of-neurological-recovery-after-chronic-craniovertebral-brainstem-compression
#19
Aymeric Amelot, Louis-Marie Terrier, Guillaume Lot
BACKGROUND: Neurologic manifestations of craniovertebral junction (CVJ) disease may generate dramatic brainstem damage, which could evolve to paralysis. In most cases, patients are referred with advanced neurological symptoms such as tetraplegia/paresis. The aim of this study was to identify predictive factors of favorable neurological evolution after non-traumatic brainstem compression. METHODS: A prospective study evaluated 143 consecutive patients who had undergone CVJ anterior brainstem decompression...
March 26, 2018: Acta Neurochirurgica
https://www.readbyqxmd.com/read/29580655/protection-of-the-rat-brain-from-hypothermic-circulatory-arrest-injury-by-a-chipmunk-protein
#20
Xuan Jiang, Tianxiang Gu, Yu Liu, Chun Wang, Enyi Shi, Guangwei Zhang, Zongyi Xiu
OBJECTIVES: The study objectives were to test the hypothesis that special protein exists in hibernating chipmunk albumin and whether this protein has a neuroprotective effect in Sprague-Dawley rats during deep hypothermia circulatory arrest. METHODS: Forty chipmunks were allocated into a hibernation group and an active group (20 chipmunks in each group). Special protein was detected and isolated from hibernating chipmunk albumin. Forty Sprague-Dawley rats were randomly divided into a sham group, deep hypothermia circulatory arrest group, special protein group, and naloxone group (10 rats in each group)...
February 24, 2018: Journal of Thoracic and Cardiovascular Surgery
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