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https://www.readbyqxmd.com/read/28731366/chondromyxoid-fibroma-of-the-distal-fibula-treated-by-percutaneous-radiofrequency-ablation
#1
Tamar Berenstein-Weyel, Ehud Lebel, Daniela Katz, Yaakov Applbaum, Amos Peyser
BACKGROUND: Percutaneous radiofrequency ablation (RFA) has been shown to be an effective treatment for soft tissue lesions and also benign bone tumors, especially osteoid osteoma. There are limited data regarding this technique in other bone tumors, specifically larger and more aggressive ones. PURPOSES: To describe the use of RFA as a definitive treatment and an alternative to traditional open surgery for the treatment of chondromyxoid fibroma (CMF), a benign but locally aggressive bone tumor...
May 2017: Journal of Orthopaedic Surgery
https://www.readbyqxmd.com/read/28727524/development-of-a-research-agenda-focused-on-academic-health-departments
#2
Paul Campbell Erwin, Ross C Brownson, William C Livingood, C William Keck, Kathleen Amos
An academic health department (AHD) is a formal partnership between an academic institution and a governmental public health agency. Case studies have described the value of individual AHDs in the areas of student engagement, practice-based research, workforce development, and service. With growing interest in AHDs and the increasing importance of academic-practice linkages in both academic programs' and public health agencies' accreditation processes, articulating a research agenda focused on the AHD model can be useful for stimulating the research and practice fields to further develop the evidence base for AHDs...
July 20, 2017: American Journal of Public Health
https://www.readbyqxmd.com/read/28724302/efficacy-and-safety-of-vedolizumab-as-a-treatment-option-for-moderate-to-severe-refractory-ulcerative-colitis-in-two-patients-after-liver-transplant-due-to-primary-sclerosing-cholangitis
#3
Raúl Vicente Olmedo Martín, Víctor Amo Trillo, Rocío González Grande, Miguel Jiménez Pérez
Vedolizumab is a humanized IgG1 monoclonal antibody that selectively blocks the lymphocyte integrin α4β7 and prevents its interaction with endothelial adhesion molecules and subsequent transmigration to the gastrointestinal tract. The drug was approved in 2014 for the induction and maintenance treatment of ulcerative colitis and moderate to severe Crohn's disease that is refractory or intolerant to conventional treatment with corticoids and immunosuppressants and/or anti-TNFα drugs. However, inflammatory bowel disease has a variable behavior following liver transplant...
July 14, 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/28721175/conducting-a-surveillance-problem-analysis-on-poor-feedback-from-reference-laboratory-liberia-february-2016
#4
Joseph Asamoah Frimpong, Maame Pokuah Amo-Addae, Peter Adebayo Adewuyi, Casey Daniel Hall, Meeyoung Mattie Park, Thomas Knue Nagbe
The laboratory plays a major role in surveillance, including confirming the start and end of an outbreak. Knowing the causative agent for an outbreak informs the development of response strategies and management plans for a public health event. However, issues and challenges may arise that limit the effectiveness or efficiency of laboratories in surveillance. This case study applies a systematic approach to analyse gaps in laboratory surveillance, thereby improving the ability to mitigate these gaps. Although this case study concentrates on factors resulting in poor feedback from the laboratory, practise of this general approach to problem analysis will confer skills required in analysing most public health issues...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28721174/detecting-reporting-and-analysis-of-priority-diseases-for-routine-public-health-surveillance-in-liberia
#5
Joseph Asamoah Frimpong, Maame Pokuah Amo-Addae, Peter Adebayo Adewuyi, Casey Daniel Hall, Meeyoung Mattie Park, Thomas Knue Nagbe
Public health officials depend on timely, complete, and accurate surveillance data for decision making. The quality of data generated from surveillance is highly dependent on external and internal factors which may either impede or enhance surveillance activities. One way of identifying challenges affecting the quality of data generated is to conduct a data quality audit. This case study, based on an audit conducted by residents of the Liberia Frontline Field Epidemiology Training Program, was designed to be a classroom simulation of a data quality audit in a health facility...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28721173/detecting-reporting-and-analysis-of-priority-diseases-for-routine-public-health-surveillance-in-liberia
#6
Joseph Asamoah Frimpong, Meeyoung Mattie Park, Maame Pokuah Amo-Addae, Peter Adebayo Adewuyi, Thomas Knue Nagbe
An essential component of a public health surveillance system is its ability to detect priority diseases which fall within the mandate of public health officials at all levels. Early detection, reporting and response to public health events help to reduce the burden of mortality and morbidity on communities. Analysis of reliable surveillance data provides relevant information which can enable implementation of timely and appropriate public health interventions. To ensure that a resilient system is in place, the World Health Organization (WHO) has provided guidelines for detection, reporting and response to public health events in the Integrated Disease Surveillance and Response (IDSR) strategy...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28721169/investigating-an-outbreak-of-measles-in-margibi-county-liberia-october-2015
#7
Joseph Asamoah Frimpong, Maame Pokuah Amo-Addae, Peter Adebayo Adewuyi, Meeyoung Mattie Park, Casey Daniel Hall, Thomas Knue Nagbe
The emergence and re-emergence of infectious diseases highlights the need to have well-trained field epidemiologists who will be at the forefront in the fight against these diseases, especially during an outbreak. Training for outbreak investigation is most effective when participants can develop their competencies in a practical exercise. To that end, this case study was based on a measles outbreak investigation conducted in Liberia during October 2015 by Liberia Frontline Field Epidemiology Training Program (FETP) residents, simulating steps to perform outbreak investigation in a real-life situation as a field epidemiologist...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28714832/satisfaction-of-tuberculosis-patients-with-health-services-in-ghana
#8
Frank Bonsu, Felix Afutu, Nii Nortey Hanson-Nortey, Mary-Anne Ahiabu, Joshua Amo-Adjei
Purpose Within human services, client satisfaction is highly prioritised and considered a mark of responsiveness in service delivery. A large body of research has examined the concept of satisfaction from the perspective of service users. However, not much is known about how service providers construct client satisfaction. The purpose of this paper is to throw light on healthcare professionals' perspectives on patient satisfaction, using tuberculosis (TB) clinics as a case study. Design/methodology/approach In-depth interviews were conducted with 35 TB clinic supervisors purposively sampled from six out of the ten regions of Ghana...
July 10, 2017: International Journal of Health Care Quality Assurance
https://www.readbyqxmd.com/read/28711388/impact-of-13-valent-pneumococcal-conjugate-vaccine-on-pneumococcal-meningitis-in-children
#9
Jesus Ruiz-Contreras, Juan Picazo, Juan Casado-Flores, Fernando Baquero-Artigao, Teresa Hernández-Sampelayo, Enrique Otheo, Cristina Méndez, María Del Amo, César Balseiro
OBJECTIVES: To evaluate the impact of 13-valent pneumococcal conjugate vaccine on pneumococcal meningitis in children. METHODS: Children younger than 15years of age attending 27 hospitals in the Region of Madrid with confirmed pneumococcal meningitis were identified in a prospective surveillance study, from 2007 to 2015. Clinical data, neurological sequelae, pneumococcal vaccination status, serotyping and antibiotic susceptibility were recorded. RESULTS: One hundred and four cases of pneumococcal meningitis were identified, 63 during the period of routine 7-valent pneumococcal conjugate vaccine immunisation (May 2007-April 2010) and 41 during the period of 13-valent pneumococcal conjugate vaccine immunisation (May 2010-April 2015)...
July 12, 2017: Vaccine
https://www.readbyqxmd.com/read/28711053/representations-in-neural-network-based-empirical-potentials
#10
Ekin D Cubuk, Brad D Malone, Berk Onat, Amos Waterland, Efthimios Kaxiras
Many structural and mechanical properties of crystals, glasses, and biological macromolecules can be modeled from the local interactions between atoms. These interactions ultimately derive from the quantum nature of electrons, which can be prohibitively expensive to simulate. Machine learning has the potential to revolutionize materials modeling due to its ability to efficiently approximate complex functions. For example, neural networks can be trained to reproduce results of density functional theory calculations at a much lower cost...
July 14, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/28710076/opportunities-and-challenges-for-environmental-exposure-assessment-in-population-based-studies
#11
Chirag J Patel, Jacqueline Kerr, Duncan C Thomas, Bhramar Mukherjee, Beate Ritz, Nilanjan Chatterjee, Marta M Jankowska, Juliette Madan, Margaret R Karagas, Kimberly A McAllister, Leah E Mechanic, M Daniele Fallin, Christine Ladd-Acosta, Ian A Blair, Susan L Teiltelbaum, Christopher I Amos
BACKGROUND: A growing number and increasing diversity of factors are available for epidemiological studies. These measures provide new avenues for discovery and prevention yet they also raise many challenges for adoption in epidemiological investigations. METHODS: We evaluate 1) designs to investigate diseases that consider heterogeneous and multi-dimensional indicators of exposure and behavior, 2) the implementation of numerous methods to capture indicators of exposure, and 3) the analytical methods required for discovery and validation...
July 14, 2017: Cancer Epidemiology, Biomarkers & Prevention
https://www.readbyqxmd.com/read/28709102/adsorption-and-degradation-of-14-c-bisphenol-a-in-a-soil-trench
#12
Jian Shen, Xin-Ze Wang, Zhen Zhang, Yan-Ming Sui, Hai-Lu Wu, Ji-Meng Feng, Xin-Nan Tong, Zhen-Yu Zhang
Bisphenol A (BPA) has caused widespread concern among scholars as a result of its estrogenic toxicity. It exists mainly in natural waters, sediments, and soil, as well as sewage and wastewater sludge. Considering that BPA is a common environmental pollutant that is removed along with chemical oxygen demand (COD), nitrogen, and phosphorus in drainage treatment systems, it is important to research the fate of BPA in sewage treatment systems. In this research, laboratory batch experiments on soil degradation and adsorption were conducted with (14)C-BPA, aiming to discuss the transport and degradation characteristics of BPA in both simulated facilities and a soil trench...
July 11, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28708787/factors-contributing-to-the-low-survival-among-women-with-a-diagnosis-of-invasive-cervical-cancer-in-ghana
#13
Yvonne Nartey, Philip C Hill, Kwabena Amo-Antwi, Kofi M Nyarko, Joel Yarney, Brian Cox
: Cervical cancer is one of the most common cancers among women worldwide, and more than 85% of the disease occurs in low- and middle-income countries. Although it ranks as the most common cancer in Ghanaian women, there are no data available on cervical cancer survival. METHODS: Information on women with a diagnosis of cervical cancer from 2010 to 2013 was collected from the Komfo Anokye and Korle-Bu Teaching Hospitals through review of paper-based and electronic medical records (including pathology records) at the oncology units and the departments of obstetrics and gynecology...
July 13, 2017: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/28708122/role-of-zucchini-and-its-distinctive-components-in-the-modulation-of-degenerative-processes-genotoxicity-anti-genotoxicity-cytotoxicity-and-apoptotic-effects
#14
Damián Martínez-Valdivieso, Rafael Font, Zahira Fernández-Bedmar, Tania Merinas-Amo, Pedro Gómez, Ángeles Alonso-Moraga, Mercedes Del Río-Celestino
Zucchini (Cucurbita pepo subsp. pepo) is a seasonal vegetable with high nutritional and medical values. Many useful properties of this fruit are attributed to bioactive compounds. Zucchini fruits ("Yellow" and "Light Green" varieties) and four distinctive components (lutein, β-carotene, zeaxanthin and dehydroascorbic acid) were selected. Firstly, the lutein, β-carotene, zeaxanthin and dehydroascorbic acid contents were determined in these fruits. Then, in order to evaluate the safety and suitability of their use, different assays were carried out: (i) genotoxicity and anti-genotoxicity tests to determine the safety and DNA-protection against hydrogen peroxide; (ii) cytotoxicity; and (iii) DNA fragmentation and Annexin V/PI (Propidium Iodide) assays to evaluate the pro-apoptotic effect...
July 14, 2017: Nutrients
https://www.readbyqxmd.com/read/28707255/comparative-clinical-study-of-whitestar-signature-phacoemulsification-system-with-standard-and-ellips-fx-handpieces
#15
Daniele Tognetto, Rossella D'Aloisio, Paolo Cecchini, Marta Di Nicola, Giuseppe Di Martino
PURPOSE: To compare the intraoperative parameters and postoperative outcomes using two different phaco handpieces with different energy delivery systems of the same phacoemulsification machine. METHODS: One hundred and sixty eyes of 160 cataract patients were randomly assigned to 2.40 mm phacoemulsification using the AMO WhiteStar Signature(®) phaco system with the standard phaco handpiece (Group 1) or the Ellips FX phaco handpiece (Group 2). According to the lens opacities classification system III, each group was divided into four subgroups of 20 patients each...
July 13, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28705670/empiric-antibiotic-protocols-for-cancer-patients-with-neutropenia-a-single-center-study-of-treatment-efficacy-and-mortality-in-patients-with-bacteremia
#16
Eyal Kleinhendler, Matan J Cohen, Allon E Moses, Ora Paltiel, Jacob Strahilevitz, Amos Cahan
BACKGROUND: A number of empiric antibiotic treatment options for febrile neutropenia exist, yet there is no universally-accepted initial protocol. We aimed to assess the performance of a protocol (piperacillin, gentamicin and cefazolin) introduced over 40 years ago and compare its coverage against bacteria isolated from blood of neutropenic patients to that of various commonly used antibiotic treatment protocols. METHODS: Adults with neutropenia admitted between 2003 and 2012 to the hemato-oncologic departments, in whom blood cultures were taken on admission were included...
July 10, 2017: International Journal of Antimicrobial Agents
https://www.readbyqxmd.com/read/28705241/demand-and-willingness-to-pay-for-bed-nets-in-tanzania-results-from-a-choice-experiment
#17
Chris D Gingrich, Emily Ricotta, Amos Kahwa, Catherine Kahabuka, Hannah Koenker
BACKGROUND: Universal coverage campaigns for long-lasting insecticide-treated nets do not always reach the goal of one net for every two household members, and even when ownership of at least one net per household is high, many households may not own enough nets. The retail market provides these households options for replacing or increasing the number of nets they own with products that best fit their needs since a variety of net shapes, sizes, and colours are available. Hence, it is important to understand the factors affecting private net demand...
July 14, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28699174/inherited-variation-in-circadian-rhythm-genes-and-risks-of-prostate-cancer-and-three-other-cancer-sites-in-combined-cancer-consortia
#18
Fangyi Gu, Han Zhang, Paula L Hyland, Sonja Berndt, Susan M Gapstur, William Wheeler, Christopher I Amos, Stephane Bezieau, Heike Bickeböller, Hermann Brenner, Paul Brennan, Jenny Chang-Claude, David V Conti, Jennifer Ann Doherty, Stephen B Gruber, Tabitha A Harrison, Richard B Hayes, Michael Hoffmeister, Richard S Houlston, Rayjean J Hung, Mark A Jenkins, Peter Kraft, Kate Lawrenson, James McKay, Sarah Markt, Lorelei Mucci, Catherine M Phelan, Conghui Qu, Angela Risch, Mary Anne Rossing, H-Erich Wichmann, Jianxin Shi, Eva Schernhammer, Kai Yu, Maria Teresa Landi, Neil E Caporaso
Circadian disruption has been linked to carcinogenesis in animal models, but the evidence in humans is inconclusive. Genetic variation in circadian rhythm genes provides a tool to investigate such associations. We examined associations of genetic variation in nine core circadian rhythm genes and six melatonin pathway genes with risk of colorectal, lung, ovarian and prostate cancers using data from the Genetic Associations and Mechanisms in Oncology (GAME-ON) network. The major results for prostate cancer were replicated in the Prostate, Lung, Colorectal and Ovarian (PLCO) cancer screening trial, and for colorectal cancer in the Genetics and Epidemiology of Colorectal Cancer Consortium (GECCO)...
July 12, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/28692791/multistimuli-response-micro-and-nanolayers-of-a-coordination-polymer-based-on-cu2-i2-chains-linked-by-2-aminopyrazine
#19
J Conesa-Egea, J Gallardo-Martínez, S Delgado, J I Martínez, J Gonzalez-Platas, V Fernández-Moreira, U R Rodríguez-Mendoza, P Ocón, F Zamora, P Amo-Ochoa
A nonporous laminar coordination polymer of formula [Cu2 I2 (2-aminopyrazine)]n is prepared by direct reaction between CuI and 2-aminopyrazine, two industrially available building blocks. The fine tuning of the reaction conditions allows obtaining [Cu2 I2 (2-aminopyrazine)]n in micrometric and nanometric sizes with same structure and composition. Interestingly, both materials show similar reversible thermo- and pressure-luminescent response as well as reversible electrical response to volatile organic solvents such as acetic acid...
July 10, 2017: Small
https://www.readbyqxmd.com/read/28691820/oxidative-1-2-brook-rearrangements-exploiting-single-electron-transfer-photoredox-catalyzed-alkylations-and-arylations
#20
Yifan Deng, Qi Liu, Amos B Smith
Oxidative [1,2]-Brook rearrangements via hypervalent silicon intermediates induced by photoredox-catalyzed single-electron transfer have been achieved, permitting the formation of reactive radical species that can engage in alkylations and arylations.
July 10, 2017: Journal of the American Chemical Society
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