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vertical sleeve gastrectomy

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https://www.readbyqxmd.com/read/28292401/what-bariatric-surgery-can%C3%A2-teach-us-about-endoluminal-treatment-of-obesity%C3%A2-and-metabolic-disorders
#1
REVIEW
Lee M Kaplan
Bariatric surgical procedures, including gastric bypass, vertical sleeve gastrectomy, and biliopancreatic diversion, are the most effective and durable treatments for obesity. In addition, These operations induce metabolic changes that provide weight-independent improvement in type 2 diabetes, fatty liver disease and other metabolic disorders. Initially thought to work by mechanical restriction of food intake or malabsorption of ingested nutrients, these procedures are now known to work through complex changes in neuroendocrine and immune signals emanating from the gut, including peptide hormones, bile acids, vagal nerve activity, and metabolites generated by the gut microbiota, all collaborating to reregulate appetite, food preference, and energy expenditure...
April 2017: Gastrointestinal Endoscopy Clinics of North America
https://www.readbyqxmd.com/read/28224471/five-year-outcomes-after-vertical-sleeve-gastrectomy-for-severe-obesity-a-prospective-cohort-study
#2
Tone Nygaard Flølo, John R Andersen, Ronette L Kolotkin, Anny Aasprang, Gerd K Natvig, Karl O Hufthammer, Villy Våge
BACKGROUND: We present 5-year outcomes after vertical sleeve gastrectomy (VSG), including complications and revisions, weight change, obesity-related diseases and health-related quality of life (HRQOL). METHODS: Patients operated from December 2005 to November 2010 were included. All variables except HRQOL (obtained using Short Form-36) were assessed prospectively. HRQOL data was assessed cross-sectionally, comparing 5-year results to both a baseline cohort of severely obese patients prior to bariatric surgery and to Norwegian norms...
February 21, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28210965/techniques-of-single-stage-laparoscopic-conversion-of-roux-en-y-gastric-bypass-to-single-anastomosis-bilio-pancreatic-diversion-with-duodenal-switch
#3
Muhammad A Jawad, Lars Nelson, Rena C Moon, Andre F Teixeira
BACKGROUND: Conversion of Roux-en-Y gastric bypass (RYGB) to single anastomosis duodenal switch can be a complicated and time-consuming operation for surgeons. PURPOSE: The purpose of this article is to present our technique of single-step laparoscopic conversion of RYGB to single anastomosis duodenal switch bilio-pancreatic diversion and vertical sleeve gastrectomy, creating a 250-cm common channel. MATERIAL AND METHODS: A laparoscopic technique was utilized in the conversion...
February 16, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28149499/bariatric-surgery-emphasizes-biological-sex-differences-in-rodent-hepatic-lipid-handling
#4
Bernadette E Grayson, Ruth Gutierrez-Aguilar, Joyce E Sorrell, Emily K Matter, Michelle R Adams, Philip Howles, Rebekah Karns, Randy J Seeley, Darleen A Sandoval
BACKGROUND: Eighty percent of patients who receive bariatric surgery are women, yet the majority of preclinical studies are in male rodents. Because sex differences drive hepatic gene expression and overall lipid metabolism, we sought to determine whether sex differences were also apparent in these endpoints in response to bariatric surgery. METHODS: Two cohorts of age-matched virgin male and female Long-Evans rats were placed on a high fat diet for 3 weeks and then received either Sham or vertical sleeve gastrectomy (VSG), a surgery which resects 80% of the stomach with no intestinal rearrangement...
2017: Biology of Sex Differences
https://www.readbyqxmd.com/read/28145963/weight-loss-outcomes-in-laparoscopic-vertical-sleeve-gastrectomy-lvsg-versus-laparoscopic-roux-en-y-gastric-bypass-lrygb-procedures-a-meta-analysis-and-systematic-review-of-randomized-controlled-trials
#5
Emma Osland, Rossita M Yunus, Shahjahan Khan, Breda Memon, Muhammed A Memon
PURPOSE: Laparoscopic Roux-en-Y gastric bypass (LRYGB) and laparoscopic vertical sleeve gastrectomy (LVSG) have been proposed as cost-effective strategies to manage morbid obesity. The aim of this meta-analysis was to compare the postoperative weight loss outcomes reported in randomized control trials (RCTs) for LVSG versus LRYGB procedures. MATERIAL AND METHODS: RCTs comparing the weight loss outcomes following LVSG and LRYGB in adult population between January 2000 and November 2015 were selected from PubMed, Medline, Embase, Science Citation Index, Current Contents, and the Cochrane database...
February 2017: Surgical Laparoscopy, Endoscopy & Percutaneous Techniques
https://www.readbyqxmd.com/read/28093508/vertical-sleeve-gastrectomy-reduces-blood-pressure-and-hypothalamic-endoplasmic-reticulum-stress-in-mice
#6
Anne K McGavigan, Zachariah M Henseler, Darline Garibay, Scott D Butler, Sisitha Jayasinghe, Ruth E Ley, Robin L Davisson, Bethany P Cummings
Bariatric surgery, such as vertical sleeve gastrectomy (VSG), causes remarkable improvements in cardiometabolic health, including hypertension remission. However, the mechanisms responsible remain undefined and poorly studied. Therefore, we developed and validated the first murine model of VSG that recapitulates the blood pressure lowering effect of VSG using gold-standard radiotelemetry technology. We used this model to investigate several potential mechanisms, including body weight, brain endoplasmic reticulum (ER) stress signaling and brain inflammatory signaling, all critical contributors to obesity-associated hypertension pathogenesis...
January 12, 2017: Disease Models & Mechanisms
https://www.readbyqxmd.com/read/28079243/serum-levels-of-vitamin-a-visual-function-and-ocular-surface-after-bariatric-surgery
#7
Luana Paula Nogueira de Araújo Brandão, Lucio Vilar, Bernardo Menelau Cavalcanti, Pedro Henrique Amorim Brandão, Tiago Eugênio Faria E Arantes, Josemberg Marins Campos
BACKGROUND: - Bariatric surgery is the most effective treatment for severe obesity, but the surgery increases the risk of developing nutritional deficiencies, such as vitamin A deficiency. In human metabolism, vitamin A plays a role in vision. OBJECTIVE: - To evaluate serum vitamin A, visual function and ocular surface of patients undergoing bariatric surgery. METHODS: - A cross-sectional and analytical study was conduced with 28 patients undergoing bariatric surgery for at least 6 months...
January 2017: Arquivos de Gastroenterologia
https://www.readbyqxmd.com/read/28076485/glp-2-a-poorly-understood-mediator-enrolled-in-various-bariatric-metabolic-surgery-related-pathophysiologic-mechanisms
#8
REVIEW
Everton Cazzo, Martinho Antonio Gestic, Murillo Pimentel Utrini, Felipe David Mendonça Chaim, Bruno Geloneze, José Carlos Pareja, Elinton Adami Chaim, Daniéla Oliveira Magro
Introduction: Glucagon-like peptide-2 (GLP-2) is a gastrointestinal hormone whose effects are predominantly trophic on the intestinal mucosa. Aim: Critically evaluate the current literature on the influence of bariatric/metabolic surgery on the levels of GLP-2 and its potential clinical implications. Method: s: Narrative review through online research on the databases Medline and Lilacs. There were six prospective human studies, two cross-sectional human studies, and three experimental animal studies selected...
November 2016: Arquivos Brasileiros de Cirurgia Digestiva: ABCD, Brazilian Archives of Digestive Surgery
https://www.readbyqxmd.com/read/28058017/dysphagia-after-vertical-sleeve-gastrectomy-evaluation-of-risk-factors-and-assessment-of-endoscopic-intervention
#9
Anand Nath, Sayali Yewale, Tung Tran, John S Brebbia, Timothy R Shope, Timothy R Koch
AIM: To evaluate the risks of medical conditions, evaluate gastric sleeve narrowing, and assess hydrostatic balloon dilatation to treat dysphagia after vertical sleeve gastrectomy (VSG). METHODS: VSG is being performed more frequently worldwide as a treatment for medically-complicated obesity, and dysphagia is common post-operatively. We hypothesize that post-operative dysphagia is related to underlying medical conditions or narrowing of the gastric sleeve. This is a retrospective, single institution study of consecutive patients who underwent sleeve gastrectomy from 2013 to 2015...
December 21, 2016: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28051892/what-is-the-role-of-bariatric-surgery-in-the-management-of-obesity
#10
REVIEW
E Panteliou, A D Miras
Diet, exercise, cognitive behavioral therapy and pharmacotherapy are some of the means of assisting patients to lose weight, with bariatric surgery being the most effective. Over the last two decades, the increased awareness of the systemic benefits of bariatric surgery, as well as the improved safety and the wider use of the laparoscopic approach, has made bariatric surgery flourish. In the United Kingdom, the adjustable gastric band (10%), vertical sleeve gastrectomy (37%) and Roux-en-Y gastric bypass (45%) are the three most common procedures...
April 2017: Climacteric: the Journal of the International Menopause Society
https://www.readbyqxmd.com/read/28008465/five-year-results-of-laparoscopic-sleeve-gastrectomy-for-the-treatment-of-severe-obesity
#11
David Nocca, Marcelo Loureiro, El Mehdi Skalli, Marius Nedelcu, Audrey Jaussent, Melanie Deloze, Patrick Lefebvre, Jean Michel Fabre
BACKGROUND: Since 2011, the most used bariatric technique in France has been the sleeve gastrectomy. There are still few studies exploring the medium and long-term results of this technique. OBJECTIVE: To describe medium-long-term (5 years) results of a cohort of CHU Montpellier experience in sleeve gastrectomy for morbid obesity. METHODS: All patients that underwent laparoscopic sleeve gastrectomy (LSG) from January 2005 to June 2013 were included in this study...
December 23, 2016: Surgical Endoscopy
https://www.readbyqxmd.com/read/28004304/changes-in-fasting-and-prandial-gut-and-adiposity-hormones-following-vertical-sleeve-gastrectomy-or-roux-en-y-gastric-bypass-an-18-month-prospective-study
#12
Naji Alamuddin, Marion L Vetter, Rexford S Ahima, Louise Hesson, Scott Ritter, Alyssa Minnick, Lucy F Faulconbridge, Kelly C Allison, David B Sarwer, Jesse Chittams, Noel N Williams, Matthew R Hayes, James W Loughead, Ruben Gur, Thomas A Wadden
BACKGROUND: Vertical sleeve gastrectomy (VSG) and Roux-en-Y gastric bypass (RYGB) produce substantial weight loss, both primarily through gastric restriction but with potentially different hormonal signaling. This prospective, observational study compared changes in gut-derived hormones in VSG, RYGB, and weight-stable participants at 6 and 18 months post-surgery. METHODS: Sixty-four obese, non-diabetic women, including 18 VSG, 23 RYGB, and 23 weight-stable controls completed assessments at baseline and 6 months, before and after consuming a mixed-nutrient meal; blood sampling occurred for 180 min post-meal...
December 21, 2016: Obesity Surgery
https://www.readbyqxmd.com/read/27912678/the-physiology-and-molecular-underpinnings-of-the-effects-of-bariatric-surgery-on-obesity-and-diabetes
#13
Simon S Evers, Darleen A Sandoval, Randy J Seeley
Bariatric surgeries, such as Roux-en-Y gastric bypass and vertical sleeve gastrectomy, produce significant and durable weight loss in both humans and rodents. Recently, these surgical interventions have also been termed metabolic surgery because they result in profound metabolic improvements that often surpass the expected improvement due to body weight loss alone. In this review we focus on the weight-loss independent effects of bariatric surgery, which encompass energy expenditure and macronutrient preference, the luminal composition of the gut (i...
February 10, 2017: Annual Review of Physiology
https://www.readbyqxmd.com/read/27900077/selective-beneficial-cardiometabolic-effects-of-vertical-sleeve-gastrectomy-are-predominantly-mediated-through-glucagon-like-peptide-glp-1-in-zucker-diabetic-fatty-rats
#14
Sunil Kumar, Raymond Lau, Thomas Palaia, Christopher Hall, Jenny Lee, Keneth Hall, Collin E Brathwaite, Louis Ragolia
BACKGROUND: Glucagon-like peptide-1 (GLP-1) level was significantly increased post Vertical Sleeve Gastrectomy (VSG), an effect believed to contribute to its beneficial cardiometabolic effects. OBJECTIVE: To validate the beneficial GLP-1 mediated cardiometabolic effects post VSG using GLP-1 antagonist (exendin 9-39) in Zucker diabetic fatty rats. METHODS: Animals were divided into three (n = 5) groups: (i) sham, (ii) VSG, and (iii) VSG received exendin 9-39 (GLP-1 receptor antagonist)...
December 2016: Annals of Medicine and Surgery
https://www.readbyqxmd.com/read/27896647/changes-in-non-diabetic-comorbid-disease-status-following-laparoscopic-vertical-sleeve-gastrectomy-lvsg-versus-laparoscopic-roux-en-y-gastric-bypass-lrygb-procedures-a-systematic-review-of-randomized-controlled-trials
#15
Emma Osland, Rossita Mohamad Yunus, Shahjahan Khan, Breda Memon, Muhammed Ashraf Memon
PURPOSE: Laparoscopic Roux-en-Y gastric bypass (LRYGB) and laparoscopic vertical sleeve gastrectomy (LVSG) have been proposed as cost-effective strategies to manage obesity-related chronic disease. The aim of this systematic review was to study the peer review literature regarding postoperative nondiabetic comorbid disease resolution or improvement reported from randomized controlled trials (RCTs) comparing LVSG and LRYGB procedures. MATERIAL AND METHODS: RCTs comparing postoperative comorbid disease resolution such as hypertension, dyslipidemia, obstructive sleep apnea, joint and musculoskeletal conditions, gastroesophageal reflux disease, and menstrual irregularities following LVSG and LRYGB were included for analysis...
November 28, 2016: Obesity Surgery
https://www.readbyqxmd.com/read/27895003/effect-on-nitrogen-balance-thermogenesis-body-composition-satiety-and-circulating-branched-chain-amino-acid-levels-up-to-one-year-after-surgery-protocol-of-a-randomized-controlled-trial-on-dietary-protein-during-surgical-weight-loss
#16
Violeta Moizé, Xavier Pi-Sunyer, Josep Vidal, Patricia Miner, Yves Boirie, Blandine Laferrère
BACKGROUND: Bariatric surgery (BS), the most effective treatment for severe obesity, typically results in 40-50 kg weight loss in the year following the surgery. Beyond its action on protein metabolism, dietary protein intake (PI) affects satiety, thermogenesis, energy efficiency, and body composition (BC). However, the required amount of PI after surgical weight loss is not known. The current daily PI recommendation for diet-induced weight loss is 0.8 g/kg ideal body weight (IBW) per day, but whether this amount is sufficient to preserve fat-free mass during active surgical weight loss is unknown...
November 28, 2016: JMIR Research Protocols
https://www.readbyqxmd.com/read/27875844/fracture-of-a-self-expanding-metal-stent-used-to-manage-a-post-vertical-sleeve-gastrectomy-stenosis
#17
Samuel Fernandes, Carlos Ferreira, Joao Lopes, João Raposo, José Velosa
No abstract text is available yet for this article.
January 2016: Endoscopy
https://www.readbyqxmd.com/read/27844255/a-vertically-placed-clip-for-weight-loss-a-39-month-pilot-study
#18
Moises Jacobs, Natan Zundel, Gustavo Plasencia, Prospero Rodriguez-Pumarol, Eddie Gomez, James Leithead
BACKGROUND: Morbid obesity remains one of society's significant medical dilemmas. It is rapidly worsening and expected to affect 35% of the US population by the year 2020. Common current bariatric procedures exist and include, but not limited to, the adjustable gastric band, gastric bypass, and the sleeve gastrectomy. Although beneficial to morbidly obese patients, they also alter the patient's anatomy and involve resections, or require maintenance. The goal of the trial is to show a new minimally invasive vertical gastric clip technique that produces significant weight loss but requires no resection, no change in anatomy, and is reversible...
November 14, 2016: Obesity Surgery
https://www.readbyqxmd.com/read/27828603/vertical-gastrectomy-in-overweight-and-non-overweight-rats
#19
Fernando Issamu Tabushi, Melissa Spena Stueber, Benur Polonio, João Carlos Domingues Repka, Sérgio Ossamu Ioshii, Paulo Afonso Nunes Nassif
PURPOSE: To compare the two lines suture (total and seromuscular) after partial gastrectomy in normal and overweight rats. METHODS: Forty Wistar rats were distributed in two groups. Group A received normal diet; group B, normal diet and supplementation with saccharose in the water. When group B progressed to a statistically greater weight than the animals of group A, the experiment (sleeve-like gastrectomy) was conducted with gastrorraphy in two sutures lines (total and seromuscular)...
October 2016: Acta Cirúrgica Brasileira
https://www.readbyqxmd.com/read/27801704/vertical-sleeve-gastrectomy-improves-indices-of-metabolic-disease-in-rodent-model-of-surgical-menopause
#20
William J Lawson, Kristin Shirey, Redin A Spann, Carlos A Zamarripa, Jonathan P Hosler, Bernadette E Grayson
OBJECTIVE: Although women are the most common recipients of weight loss surgeries for the amelioration of the comorbidities of obesity, few studies have addressed the efficacy of these procedures with specific attention to reproductive stage. Here we ask in a rodent model of vertical sleeve gastrectomy (VSG) whether improvements to metabolic health are realized in women having received surgical menopause. Specifically we were interested in knowing whether rats made menopausal through surgical means would exhibit persistent hepatic steatosis as reported in previously pregnant, freely cycling female VSG rats or if it is resolved as reported in male VSG rats...
October 31, 2016: Menopause: the Journal of the North American Menopause Society
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