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Trial of labour

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https://www.readbyqxmd.com/read/27922285/a-prospective-randomized-trial-comparing-foley-catheter-oxytocin-and-combination-foley-catheter-oxytocin-for-labour-induction-with-unfavourable-cervix
#1
Nabih I El Khouly
The purpose of this study was to evaluate the effectiveness and safety of transcervical Foley catheter with and without oxytocin versus oxytocin alone for labour induction with unfavourable cervix. This trial enrolled 108 women with singleton pregnancies presented for labour induction with unfavourable cervix. Patients were randomly assigned to receive Foley catheter alone (I), Foley catheter plus oxytocin (II) or oxytocin alone (III). Outcomes were analysed in terms of success of induction, induction delivery interval, route of delivery, dose and duration of oxytocin, and complications...
December 6, 2016: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/27921380/induction-of-labour-for-suspected-macrosomia-at-term-in-non-diabetic-women-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#2
REVIEW
E R Magro-Malosso, G Saccone, M Chen, R Navathe, M Di Tommaso, V Berghella
BACKGROUND: Several randomized controlled trials (RCTs) compared induction of labour with expectant management in non-diabetic women with suspected fetal macrosomia. OBJECTIVE: To evaluate the effects of labour induction for suspected fetal macrosomia. SEARCH STRATEGY: Literature search in electronic databases. SELECTION CRITERIA: We included all RCTs of suspected fetal macrosomia comparing labour induction with expectant management in term pregnancy...
December 5, 2016: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/27918616/nitric-oxide-donors-for-cervical-ripening-and-induction-of-labour
#3
REVIEW
Arpita Ghosh, Katherine R Lattey, Anthony J Kelly
BACKGROUND: Sometimes it is necessary to bring on labour artificially because of safety concerns for the mother or baby. This review is one of a series of reviews of methods of labour induction using a standardised protocol. OBJECTIVES: To determine the effects of NO donors (isosorbide mononitrate (ISMN), isosorbide dinitrate (ISDN), nitroglycerin and sodium nitroprusside) for third trimester cervical ripening or induction of labour, in comparison with placebo or no treatment or other treatments from a predefined hierarchy...
December 5, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27884664/bacterial-contamination-of-saline-used-for-epidural-procedures-in-an-obstetric-setting-a-randomised-comparison-of-two-drawing-up-techniques
#4
M Onofrei, M Y Wee, B Parker, N Wee, S Hill
BACKGROUND: There is little evidence to inform practice regarding the optimum aseptic technique of drawing up saline for epidural insertion. Our regional practice is to draw up saline from a non-sterile packaged plastic ampoule, therefore introducing the risk of bacterial contamination. Usually, the anaesthetist draws up saline directly from the vial held by an assistant using a needle (needle technique). Alternatively, the saline vial is emptied onto a sterile tray by an assistant and then drawn up by the anaesthetist (tray technique)...
October 8, 2016: International Journal of Obstetric Anesthesia
https://www.readbyqxmd.com/read/27862573/association-between-change-in-employment-participation-and-quality-of-life-in-middle-aged-colorectal-cancer-survivors-compared-with-general-population-controls
#5
Vanessa L Beesley, Jeff K Vallance, Gabor Mihala, Brigid M Lynch, Louisa G Gordon
OBJECTIVE: To examine the association between change in employment participation over a 12-month period and quality of life among individuals with colorectal cancer compared to general population controls. METHODS: This was a prospective, registry-based study that enrolled middle-aged (45-64 years) residents of Queensland, Australia, who were in the paid workforce, and newly-diagnosed with colorectal cancer. Participants completed structured telephone interviews at six and 12 months after diagnosis assessing quality of life and employment status ('retired/ceased work', 'increased work', 'decreased work' and 'maintained work')...
November 8, 2016: Psycho-oncology
https://www.readbyqxmd.com/read/27832753/stillbirths-and-quality-of-care-during-labour-at-the-low-resource-referral-hospital-of-zanzibar-a-case-control-study
#6
Nanna Maaløe, Natasha Housseine, Ib Christian Bygbjerg, Tarek Meguid, Rashid Saleh Khamis, Ali Gharib Mohamed, Birgitte Bruun Nielsen, Jos van Roosmalen
BACKGROUND: To study determinants of stillbirths as indicators of quality of care during labour in an East African low resource referral hospital. METHODS: A criterion-based unmatched unblinded case-control study of singleton stillbirths with birthweight ≥2000 g (n = 139), compared to controls with birthweight ≥2000 g and Apgar score ≥7 (n = 249). RESULTS: The overall facility-based stillbirth rate was 59 per 1000 total births, of which 25 % was not reported in the hospital's registers...
November 10, 2016: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/27827958/high-throughput-phenotyping-of-wheat-and-barley-plants-grown-in-single-or-few-rows-in-small-plots-using-active-and-passive-spectral-proximal-sensing
#7
Gero Barmeier, Urs Schmidhalter
In the early stages of plant breeding, breeders evaluate a large number of varieties. Due to limited availability of seeds and space, plot sizes may range from one to four rows. Spectral proximal sensors can be used in place of labour-intensive methods to estimate specific plant traits. The aim of this study was to test the performance of active and passive sensing to assess single and multiple rows in a breeding nursery. A field trial with single cultivars of winter barley and winter wheat with four plot designs (single-row, wide double-row, three rows, and four rows) was conducted...
November 5, 2016: Sensors
https://www.readbyqxmd.com/read/27825616/vandetanib-in-patients-with-previously-treated-ret-rearranged-advanced-non-small-cell-lung-cancer-luret-an-open-label-multicentre-phase-2-trial
#8
Kiyotaka Yoh, Takashi Seto, Miyako Satouchi, Makoto Nishio, Noboru Yamamoto, Haruyasu Murakami, Naoyuki Nogami, Shingo Matsumoto, Takashi Kohno, Koji Tsuta, Katsuya Tsuchihara, Genichiro Ishii, Shogo Nomura, Akihiro Sato, Atsushi Ohtsu, Yuichiro Ohe, Koichi Goto
BACKGROUND: RET rearrangements are rare oncogenic alterations in non-small-cell lung cancer (NSCLC). Vandetanib is a multitargeted tyrosine kinase inhibitor exhibiting RET kinase activity. We aimed to assess the efficacy and safety of vandetanib in patients with advanced RET-rearranged NSCLC. METHODS: In this open-label, multicentre, phase 2 trial (LURET), patients with advanced RET-rearranged NSCLC continuously received 300 mg of oral vandetanib daily. RET-positive patients were screened using a nationwide genomic screening network of about 200 participating institutions...
November 4, 2016: Lancet Respiratory Medicine
https://www.readbyqxmd.com/read/27821151/-i-ve-changed-my-mind-mindfulness-based-childbirth-and-parenting-mbcp-for-pregnant-women-with-a-high-level-of-fear-of-childbirth-and-their-partners-study-protocol-of-the-quasi-experimental-controlled-trial
#9
Irena K Veringa, Esther I de Bruin, Nancy Bardacke, Larissa G Duncan, Francisca J A van Steensel, Carmen D Dirksen, Susan M Bögels
BACKGROUND: Approximately 25 % of pregnant women suffer from a high level of Fear of Childbirth (FoC), as assessed by the Wijma Delivery Expectancy Questionnaire (W-DEQ-A, score ≥66). FoC negatively affects pregnant women's mental health and adaptation to the perinatal period. Mindfulness-Based Childbirth and Parenting (MBCP) seems to be potentially effective in decreasing pregnancy-related anxiety and stress. We propose a theoretical model of Avoidance and Participation in Pregnancy, Birth and the Postpartum Period in order to explore FoC and to evaluate the underlying mechanisms of change of MBCP...
November 7, 2016: BMC Psychiatry
https://www.readbyqxmd.com/read/27813240/immediate-delivery-or-expectant-management-in-gestational-diabetes-at-term-the-ginexmal-randomised-controlled-trial
#10
S Alberico, A Erenbourg, M Hod, Y Yogev, E Hadar, F Neri, L Ronfani, G Maso
OBJECTIVE: To evaluate maternal and perinatal outcomes after induction of labour versus expectant management in pregnant women with gestational diabetes at term. DESIGN: Multicentre open-label randomised controlled trial. SETTING: Eight teaching hospitals in Italy, Slovenia, and Israel. SAMPLE: Singleton pregnancy, diagnosed with gestational diabetes by the International Association of Diabetes and Pregnancy Study Groups criteria (IADPSGC), between 38(+0) and 39(+0) weeks of gestation, without other maternal or fetal conditions...
November 4, 2016: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/27806709/benefits-and-harms-of-screening-for-and-treatment-of-asymptomatic-bacteriuria-in-pregnancy-a-systematic-review
#11
Konstanze Angelescu, Barbara Nussbaumer-Streit, Wiebke Sieben, Fülöp Scheibler, Gerald Gartlehner
BACKGROUND: Most European and North American clinical practice guidelines recommend screening for asymptomatic bacteriuria (ASB) as a routine pregnancy test. Antibiotic treatment of ASB in pregnant women is supposed to reduce maternal upper urinary tract infections (upper UTIs) and preterm labour. However, most studies supporting the treatment of ASB were conducted in the 1950s to 1980s. Because of subsequent changes in treatment options for ASB and UTI, the applicability of findings from these studies has come into question...
November 2, 2016: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/27799176/i-v-paracetamol-as-an-adjunct-to-patient-controlled-epidural-analgesia-with-levobupivacaine-and-fentanyl-in-labour-a-randomized-controlled-study
#12
K Gupta, S Mitra, S Kazal, R Saroa, V Ahuja, P Goel
BACKGROUND: Use of i.v. paracetamol for postoperative pain is well documented, but it is unclear if it can reduce the consumption of opioids during patient-controlled epidural analgesia (PCEA) in labouring parturients. METHODS: In this randomized, double-blind, placebo-controlled clinical trial conducted in a tertiary care hospital, (80)parturients were randomly assigned to two groups of 40 each, to receive either 1000 mg (100 ml) i.v. paracetamol or 100 ml normal saline as placebo, 30 min before the procedure...
November 2016: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/27790526/effect-of-continued-support-of-midwifery-students-in-labour-on-the-childbirth-and-labour-consequences-a-randomized-controlled-clinical-trial
#13
Nahid Bolbol-Haghighi, Seyedeh Zahra Masoumi, Farideh Kazemi
INTRODUCTION: Childbirth experience is a process throughout women's life and the most important consequence of labour. Support is the key factor to have a positive experience of childbirth. In order to improve and reduce the stress and anxiety levels in women during labour and cope with the childbirth pain, the emotional, physical and educational support of doulas can be used. AIM: This study was aimed to evaluate the effect of continued support of midwifery students in labour on the childbirth and labour consequences...
September 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27790522/the-effect-of-oxygen-inhalation-plus-oxytocin-compared-with-oxytocin-only-on-postpartum-haemorrhage-a-randomized-clinical-trial
#14
Zainab Suhrabi, Hamid Taghinejad, Ashraf Direkvand-Moghadam, Malihe Akbari
INTRODUCTION: Post Partum Haemorrhage (PPH) is the leading cause of maternal mortality across the world, mainly in the developing countries. AIM: The present study was conducted with the aim to investigate effect of oxygen inhalation plus oxytocin compared with oxytocin only on PPH. MATERIALS AND METHODS: This study was a clinical trial which was performed in Shahid Mustafa Khomieni Teaching Hospital of Ilam (western Iran) from April 2012 to Nov 2013...
September 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27771320/-no-pain-no-gain-the-experience-of-women-using-sterile-water-injections
#15
Nigel Lee, Sue Kildea, Helen Stapleton
PROBLEM/BACKGROUND: Sterile water injections (SWI) are gaining popularity amongst women and midwives for the relief of back pain in labour. However the brief but intense pain associated with the injection has been cited as a deterrent to use and may negatively affect the birth experience. AIM: To explore women's experiences of using sterile water injections as analgesia for back pain in labour. DESIGN: A qualitative study, which generated data through individual semi-structured interviews with postnatal women...
October 19, 2016: Women and Birth: Journal of the Australian College of Midwives
https://www.readbyqxmd.com/read/27771202/-in-case-of-fetal-macrosomia-the-best-strategy-is-the-induction-of-labor-at-38%C3%A2-weeks-of-gestation
#16
REVIEW
P Rozenberg
Macrosomic fetuses are at increased risk of obstetric complications, and notably shoulder dystocia, responsible for a severe neonatal morbidity. In case of fetal macrosomia, three options are: (i) the elective cesarean delivery, but this is recommended only when the estimated fetal weight is≥4500g for diabetic women and 5000g for non-diabetic women; (ii) the expectative management, but children with birth weight≥4500 had significantly increased risk of perinatal mortality, neonatal asphyxia, trauma, and cesarean delivery; (iii) the induction of labor which, reducing the possibility of fetal growth, reduce the risk of cesarean delivery for cephalopelvic disproportion and shoulder dystocia...
October 19, 2016: Journal de Gynécologie, Obstétrique et Biologie de la Reproduction
https://www.readbyqxmd.com/read/27765430/-obstetrical-prognosis-of-patients-after-a-previous-caesarean-section-performed-before-32-weeks-of-amenorrhea
#17
C Baeza, N Mottet, C Coppola, M Desmarets, R Ramanah, D Riethmuller
OBJECTIVE: To assess delivery mode, maternal morbidity including uterine rupture and scar dehiscence and neonatal outcome, during a pregnancy after a previous caesarean delivery before 32 weeks of amenorrhea. METHODS: A retrospective descriptive study was carried out at the Besançon University Hospital during an 8-year period. We identified 292 consecutive patients presenting a singleton pregnancy delivery before 32 weeks of amenorrhea. We analysed the next pregnancy...
November 2016: Gynécologie, Obstétrique & Fertilité
https://www.readbyqxmd.com/read/27717319/does-acupuncture-have-a-role-in-the-treatment-of-threatened-miscarriage-findings-from-a-feasibility-randomised-trial-and-semi-structured-participant-interviews
#18
Debra Betts, Caroline A Smith, Hannah G Dahlen
BACKGROUND: Threatened miscarriage is a common complication of early pregnancy increasing the risk of miscarriage or premature labour. Currently there is limited evidence to recommend any biomedical pharmacological or self-care management, resulting in a 'watchful waiting' approach. The objective of this study was to examine the feasibility of offering acupuncture as a therapeutic treatment for women presenting with threatened miscarriage. METHODS: A mixed methods study involving a randomised controlled trial and semi structured interviews...
October 7, 2016: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/27670710/management-of-spontaneous-labour-at-term%C3%A2-in-healthy-women
#19
Lily Lee, Jessica Dy, Hussam Azzam
OBJECTIVE: The purpose of this guideline is to provide guidance for the intrapartum management of spontaneous labour, whether normal or abnormal, in term, healthy women, and to provide guidance in the management of first and second stage dystocia to increase the likelihood of a vaginal birth and optimize birth outcomes. EVIDENCE: Published literature was retrieved through searches of PubMed and the Cochrane Library in October 2011 using appropriate, controlled vocabulary (e...
September 2016: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/27659557/a-simple-automated-system-for-appetitive-conditioning-of-zebrafish-in-their-home-tanks
#20
Jillian M Doyle, Neil Merovitch, Russell C Wyeth, Matthew R Stoyek, Michael Schmidt, Florentin Wilfart, Alan Fine, Roger P Croll
We describe here an automated apparatus that permits rapid conditioning paradigms for zebrafish. Arduino microprocessors were used to control the delivery of auditory or visual stimuli to groups of adult or juvenile zebrafish in their home tanks in a conventional zebrafish facility. An automatic feeder dispensed precise amounts of food immediately after the conditioned stimuli, or at variable delays for controls. Responses were recorded using inexpensive cameras, with the video sequences analysed with ImageJ or Matlab...
September 19, 2016: Behavioural Brain Research
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