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Oculomotor nerve

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https://www.readbyqxmd.com/read/28069157/mri-detection-of-cerebral-lesions-in-post-traumatic-anisocoria-specificity-and-prognostic-significance
#1
D Woischneck, B Schmitz, T Kapapa
AIM: To identify whether increased numbers of brainstem lesions are found in the presence of a post-traumatic pupillary function disturbance and classify them anatomically. MATERIALS AND METHODS: In this study, a diagnostic magnetic resonance imaging (MRI) examination was performed within 8 days after traumatic brain injury (TBI) in patients who had been unconscious for more than 24 hours post-TBI. The Glasgow Outcome Scale was evaluated 6 months after TBI. The data obtained from 140 consecutively enrolled patients between 2005 and 2011 were analysed...
January 7, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/28017901/central-serous-chorioretinopathy-following-medial-transposition-of-split-lateral-rectus-muscle-for-complete-oculomotor-nerve-palsy
#2
Rebecca Sorenson, Ajay Soni
No abstract text is available yet for this article.
December 22, 2016: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/28006728/is-clipping-better-than-coiling-in-the-treatment-of-patients-with-oculomotor-nerve-palsies-induced-by-posterior-communicating-artery-aneurysms-a-systematic-review-and-meta-analysis
#3
REVIEW
Feng Zheng, Ying Dong, Peng Xia, Anastasios Mpotsaris, Pantelis Stavrinou, Gerrit Brinker, Roland Goldbrunner, Boris Krischek
OBJECTIVE: Posterior communicating artery aneurysms (PcomAAs) are the second most common aneurysm, accounting for 25% of all aneurysms and 50% of internal carotid artery aneurysms. It has been estimated that oculomotor nerve palsy (ONP) occurs in up to one-third of patients with posterior communicating artery (PcomA) aneurysms. Recent research showed a better outcome of ONP in patients with PcomAA after surgical clipping when compared to endovascular coiling. We compared the effect of clipping and coiling on recovery of ONP in the management of patients with PcomAAs...
December 11, 2016: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/27977032/multiple-pathological-ocular-findings-in-a-patient-with-phace-syndrome
#4
Elif Demirkilinc Biler, Onder Uretmen
The authors describe a 2-year-old girl diagnosed as having posterior fossa malformations, hemangiomas, arterial anomalies, cardiac anomalies, and eye abnormalities (PHACE) syndrome that presented with a large facial hemangioma of the forehead and eyelid, ptosis, microphthalmia, persistent pupillary membrane and pupillary ectopia, congenital oculomotor nerve palsy of the affected eye, and bilateral optic disc dysplasia. [J Pediatr Ophthalmol Strabismus. 2016;53:e72-e74.].
December 8, 2016: Journal of Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/27939798/diplopia-and-sjogren-s-disease-a-rare-case-report
#5
Kaushalendra Tripathi, Richa Tripathi, Navid Seraji-Bozorgzad
Sjogren's syndrome is a chronic autoimmune disorder which affects the exocrine glands with lymphocytic infiltration, and occasionally involves central nervous system. It is usually rare and manifests as a lesion in the trigeminal nerve. Our case discusses the involvement of the oculomotor and abducens nerves along with the prevalence of such cases as seen on literature review. We describe a case of a middle aged woman who presented with ophthalmoplegic symptoms. The symptoms resolved in response to steroid therapy and serum analysis was positive for anti SSA antibodies...
January 15, 2017: Journal of Neuroimmunology
https://www.readbyqxmd.com/read/27928390/isolated-oculomotor-nerve-palsy-due-to-metastasis-of-prostatic-cancer-to-the-cavernous-sinus
#6
Yuki Asano, Keiko Takahashi, Hiromasa Tsuda, Mariko Takagi, Fumi Kodaka, Yosuke Yamada
A 69-year-old man with prostatic cancer under palliative care developed isolated right-sided oculomotor nerve palsy with pupillary impairment and persistent ocular pain. Cranial magnetic resonance imaging demonstrated metastasis of prostatic cancer to the right-sided cavernous sinus and orbital apex. In the English language literature, there are only six reported cases of isolated oculomotor nerve palsy secondary to prostatic cancer. In all cases, although there was metastatic lesion in the vicinity of the cavernous sinus, ocular pain did not develop...
April 2016: Neuro-ophthalmology
https://www.readbyqxmd.com/read/27928389/oculomotor-nerve-palsy-presented-with-isolated-unilateral-ptosis-and-minimal-upgaze-palsy
#7
Canan Togay Işıkay, Busra S Polat
This case with unilateral complete blepharoptosis and slight limitation of upgaze as ocular findings due to midbrain infarction represents an unusual form of intra-axial oculomotor nerve involvement. A 65-year-old man was admitted with acute unilateral ptosis of the left eyelid and gait ataxia. He had chronic hypertension in the medical history. The neurologic examination revealed that he had a complete ptosis of the left eyelid, slight limitation of elevation in the left eye, bilateral dysmetria, and gait ataxia...
April 2016: Neuro-ophthalmology
https://www.readbyqxmd.com/read/27928379/a-rare-case-of-penetrating-trauma-resulting-in-isolated-third-nerve-palsy
#8
Caleb Story, Michael Patterson, Wilson McWilliams, Bethany Bray Markowitz
A 23-year-old male presented to the emergency department with right eye pain, right upper eyelid ptosis, blurry vision, and binocular diplopia that developed immediately after he bent over in a parking lot and the antenna of a car penetrated his right upper eyelid. An extensive workup was performed, and he was found to have an isolated traumatic oculomotor nerve palsy with pupil involvement. No other ocular findings of a traumatic injury were present. The patient was observed for 14 months, during which he continually improved, with almost complete resolution of his diplopia, anisocoria, and ptosis...
February 2016: Neuro-ophthalmology
https://www.readbyqxmd.com/read/27927015/isolated-oculomotor-nerve-palsy-in-patients-with-mild-head-injury
#9
Tamara Tajsic, Angelos G Kolias, Tilak Das, Daniel Scoffings, Brinda Muthusamy, Matthew R Garnett, Peter J A Hutchinson
Isolated oculomotor nerve palsy following head injury is uncommon. It can only be diagnosed with confidence if it is known to have developed immediately following trauma and if adequate investigations exclude secondary causes. The recovery is only partial and this has repercussion on patients' quality of life.
December 7, 2016: British Journal of Neurosurgery
https://www.readbyqxmd.com/read/27923188/electrophysiology-in-fisher-syndrome
#10
REVIEW
Satoshi Kuwabara, Yukari Sekiguchi, Sonoko Misawa
Fisher syndrome (FS), a variant of Guillain-Barré syndrome (GBS), is characterized by the clinical triad of ophthalmoplegia, ataxia, and areflexia. The lesion sites for these unique clinical features include the oculomotor nerves and group 1a neurons in the dorsal root ganglion, and the presence of FS is determined by the expression of ganglioside GQ1b in the human nervous system. Neurophysiological findings suggest that ataxia and areflexia are due to an impaired proprioceptive afferent system. Typically, the soleus H-reflex is absent and a body-sway analysis using posturography shows a 1-Hz peak, which indicates proprioception dysfunction...
January 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/27916956/functional-diversity-of-neurotrophin-actions-on-the-oculomotor-system
#11
REVIEW
Beatriz Benítez-Temiño, María A Davis-López de Carrizosa, Sara Morcuende, Esperanza R Matarredona, Rosa R de la Cruz, Angel M Pastor
Neurotrophins play a principal role in neuronal survival and differentiation during development, but also in the maintenance of appropriate adult neuronal circuits and phenotypes. In the oculomotor system, we have demonstrated that neurotrophins are key regulators of developing and adult neuronal properties, but with peculiarities depending on each neurotrophin. For instance, the administration of NGF (nerve growth factor), BDNF (brain-derived neurotrophic factor) or NT-3 (neurotrophin-3) protects neonatal extraocular motoneurons from cell death after axotomy, but only NGF and BDNF prevent the downregulation in ChAT (choline acetyltransferase)...
December 1, 2016: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/27904500/electrical-stimulation-promotes-regeneration-of-injured-oculomotor-nerves-in-dogs
#12
Lei Du, Min Yang, Liang Wan, Xu-Hui Wang, Shi-Ting Li
Functional recovery after oculomotor nerve injury is very poor. Electrical stimulation has been shown to promote regeneration of injured nerves. We hypothesized that electrical stimulation would improve the functional recovery of injured oculomotor nerves. Oculomotor nerve injury models were created by crushing the right oculomotor nerves of adult dogs. Stimulating electrodes were positioned in both proximal and distal locations of the lesion, and non-continuous rectangular, biphasic current pulses (0.7 V, 5 Hz) were administered 1 hour daily for 2 consecutive weeks...
October 2016: Neural Regeneration Research
https://www.readbyqxmd.com/read/27903814/blink-associated-contralateral-eccentric-saccades-as-a-rare-sign-of-unilateral-brain-injury
#13
Ilaria Zivi, Eugenio Bertelli, Giacinta Bilotti, Ignazio Alessandro Clemente, Leopold Saltuari, Giuseppe Frazzitta
OBJECTIVE: To describe a rare sign of unilateral brain injury as a form of unwanted blink-associated contralateral eccentric saccades. METHODS: A 62-year-old patient who underwent an ischemic stroke affecting the entire right middle cerebral artery territory came to our attention 1 year after stroke, manifesting with transient contralateral conjugate gaze deviations associated with spontaneous blinking. We complemented the regular neurologic evaluation with brain MRI, study of evoked potentials, electroneurography of the facial nerve, and infrared video-oculoscopy...
January 10, 2017: Neurology
https://www.readbyqxmd.com/read/27886888/imaging-of-oculomotor-third-cranial-nerve-palsy
#14
REVIEW
Michael S Vaphiades, Glenn H Roberson
When evaluating a patient with an oculomotor cranial nerve palsy it may be unclear which neuroimaging modality is optimal; MRI, MR angiography, computed tomography, computed tomography angiography, or intraarterial digital subtraction angiography. We discuss the clinical guidelines in the evaluation of such patients and review neuroimaging techniques, outlining the advantages and disadvantages of each.
February 2017: Neurologic Clinics
https://www.readbyqxmd.com/read/27876664/isolated-hypertrophic-neuropathy-of-the-oculomotor-nerve
#15
Joshua J Lim, H Brent Clark, Andrew W Grande
BACKGROUND: Hypertrophic neuropathy is a rare entity commonly associated with peripheral nerve, characterized by onion bulb formations. Its cranial nerve involvement is very rare; only 7 cases have been found in the literature. CASE DESCRIPTION: A 32-year-old white man with a 5-year history of intermittent right retro-orbital headache and mild right ptosis presented to the Neurosurgery Clinic. A magnetic resonance imaging of his brain demonstrated an enhancing lesion associated with the right third nerve...
November 19, 2016: World Neurosurgery
https://www.readbyqxmd.com/read/27859787/microsurgical-anatomy-of-the-oculomotor-nerve
#16
REVIEW
Hae Kwan Park, Hyung Keun Rha, Kyung Jin Lee, Chung Kee Chough, Wonil Joo
The oculomotor nerve supplies the extraocular muscles. It also supplies the ciliary and sphincter pupillae muscles through the ciliary ganglion. The nerve fibers leave the midbrain through the most medial part of the cerebral peduncle and enter the interpeduncular cistern. After the oculomotor nerve emerges from the interpeduncular fossa, it enters the cavernous sinus slightly lateral and anterior to the dorsum sellae. It enters the orbit through the superior orbital fissure, after exiting the cavernous sinus, to innervate the extraocular muscles...
January 2017: Clinical Anatomy
https://www.readbyqxmd.com/read/27857868/surgical-anatomy-of-the-medial-wall-of-the-orbit-in-14-human-cadavers
#17
Juan R Gras-Cabrerizo, Maria Martel-Martin, Jacinto Garcia-Lorenzo, Fernando Rodríguez-Álvarez, Joan R Montserrat-Gili, Rosa Mirapeix-Lucas, Humbert Massegur-Solench
Objective The aim of our study is to present the anatomical landmarks to perform an endoscopic endonasal approach to the medial wall of the orbit (EEAMO). Material and Methods We performed 14 complete nasal and orbital endoscopic dissections in 7 adult cadaveric heads. Results The EEAMO provides a surgical corridor between the medial rectus muscle superiorly and the inferior rectus muscle inferiorly .The mean distance between the ethmoidal crest and medial rectus muscle was 1.5 cm (range, 1.3-1.9 cm)...
December 2016: Journal of Neurological Surgery. Part B, Skull Base
https://www.readbyqxmd.com/read/27843362/isolated-oculomotor-nerve-palsy-resulting-from-acute-traumatic-tentorial-subdural-hematoma
#18
Victoria Cui, Timur Kouliev
Acute subdural hematoma (SDH) resulting from head trauma is a potentially life-threatening condition that requires expedient diagnosis and intervention to ensure optimal patient outcomes. Rapidly expanding or large hematomas, elevated intracranial pressure, and associated complications of brain herniation are associated with high mortality rates and poor recovery of neurological function. However, smaller bleeds (clot thickness <10 mm) or hematomas occurring in infrequent locations, such as the tentorium cerebelli, may be difficult to recognize and patients may present with unusual or subtle signs and symptoms, including isolated cranial nerve palsies...
2016: Open Access Emergency Medicine: OAEM
https://www.readbyqxmd.com/read/27802825/mog-igg-in-nmo-and-related-disorders-a-multicenter-study-of-50-patients-part-3-brainstem-involvement-frequency-presentation-and-outcome
#19
Sven Jarius, Ingo Kleiter, Klemens Ruprecht, Nasrin Asgari, Kalliopi Pitarokoili, Nadja Borisow, Martin W Hümmert, Corinna Trebst, Florence Pache, Alexander Winkelmann, Lena-Alexandra Beume, Marius Ringelstein, Oliver Stich, Orhan Aktas, Mirjam Korporal-Kuhnke, Alexander Schwarz, Carsten Lukas, Jürgen Haas, Kai Fechner, Mathias Buttmann, Judith Bellmann-Strobl, Hanna Zimmermann, Alexander U Brandt, Diego Franciotta, Kathrin Schanda, Friedemann Paul, Markus Reindl, Brigitte Wildemann
BACKGROUND: Myelin oligodendrocyte glycoprotein antibodies (MOG-IgG) are present in a subset of aquaporin-4 (AQP4)-IgG-negative patients with optic neuritis (ON) and/or myelitis. Little is known so far about brainstem involvement in MOG-IgG-positive patients. OBJECTIVE: To investigate the frequency, clinical and paraclinical features, course, outcome, and prognostic implications of brainstem involvement in MOG-IgG-positive ON and/or myelitis. METHODS: Retrospective case study...
November 1, 2016: Journal of Neuroinflammation
https://www.readbyqxmd.com/read/27770832/contralateral-migration-of-oculomotor-neurons-is-regulated-by-slit-robo-signaling
#20
Brielle Bjorke, Farnaz Shoja-Taheri, Minkyung Kim, G Eric Robinson, Tatiana Fontelonga, Kyung-Tai Kim, Mi-Ryoung Song, Grant S Mastick
BACKGROUND: Oculomotor neurons develop initially like typical motor neurons, projecting axons out of the ventral midbrain to their ipsilateral targets, the extraocular muscles. However, in all vertebrates, after the oculomotor nerve (nIII) has reached the extraocular muscle primordia, the cell bodies that innervate the superior rectus migrate to join the contralateral nucleus. This motor neuron migration represents a unique strategy to form a contralateral motor projection. Whether migration is guided by diffusible cues remains unknown...
October 22, 2016: Neural Development
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