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https://www.readbyqxmd.com/read/29329212/study-of-the-thermal-properties-and-the-fire-performance-of-flame-retardant-organic-pcm-in-bulk-form
#1
Anabel Palacios, Alvaro De Gracia, Laia Haurie, Luisa F Cabeza, A Inés Fernández, Camila Barreneche
The implementation of organic phase change materials (PCMs) in several applications such as heating and cooling or building comfort is an important target in thermal energy storage (TES). However, one of the major drawbacks of organic PCMs implementation is flammability. The addition of flame retardants to PCMs or shape-stabilized PCMs is one of the approaches to address this problem and improve their final deployment in the building material sector. In this study, the most common organic PCM, Paraffin RT-21, and fatty acids mixtures of capric acid (CA), myristic acid (MA), and palmitic acid (PA) in bulk, were tested to improve their fire reaction...
January 12, 2018: Materials
https://www.readbyqxmd.com/read/29287744/a-spherical-treadmill-system-to-train-head-fixed-adult-rats
#2
Anabel M M Miguelez Fernández, Ariel Burman, Alfredo I Martínez Cáceres, Camilo J Mininni, B Silvano Zanutto, Sergio E Lew
BACKGROUND: While spherical treadmills are widely used in mouse models, there are only a few experimental setups suitable for adult rats, and none of them include head-fixation. NEW METHOD: We introduce a novel spherical treadmill apparatus for head-fixed rats that allows a wide repertory of natural responses. The rat is secured to a frame and placed on a freely rotating sphere. While being head-fixed, it can walk in any direction and perform different motor tasks...
December 26, 2017: Journal of Neuroscience Methods
https://www.readbyqxmd.com/read/29287238/detection-of-early-psychotic-symptoms-validation-of-the-spanish-version-of-the-symptom-onset-in-schizophrenia-sos-inventory
#3
Gisela Mezquida, Bibiana Cabrera, Anabel Martínez-Arán, Eduard Vieta, Miguel Bernardo
The period of subclinical signs that precedes the onset of psychosis is referred to as the prodrome or high-risk mental state. The "Symptom Onset in Schizophrenia (SOS) inventory" is an instrument to characterize and date the initial symptoms of a psychotic illness. The present study aims to provide reliability and validity data for clinical and research use of the Spanish version of the SOS. Thirty-six participants with a first-episode of psychosis meeting DSM-IV criteria for schizophrenia/schizoaffective/schizophreniform disorder were administered the translated SOS and other clinical assessments...
December 14, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/29250926/subepidermal-moisture-detection-of-heel-pressure-injury-the-pressure-ulcer-detection-study-outcomes
#4
Barbara M Bates-Jensen, Heather E McCreath, Gojiro Nakagami, Anabel Patlan
We examined subepidermal moisture (SEM) and visual skin assessment of heel pressure injury (PrI) among 417 nursing home residents in 19 facilities over 16 weeks. Participants were older (mean age 77 years), 58% were female, over half were ethnic minorities (29% African American, 12% Asian American, 21% Hispanic), and at risk for PrI (mean Braden Scale Risk score = 15.6). Blinded concurrent visual assessments and SEM measurements were obtained at heels weekly. Visual skin damage was categorised as normal, erythema, stage 1 PrI, deep tissue injury (DTI) or stage 2 or greater PrI...
December 17, 2017: International Wound Journal
https://www.readbyqxmd.com/read/29237343/advocacy-leadership-and-transformation
#5
Anabell Castro Thompson
No abstract text is available yet for this article.
December 2017: Hispanic Health Care International: the Official Journal of the National Association of Hispanic Nurses
https://www.readbyqxmd.com/read/29234279/long-term-effects-of-intermittent-adolescent-alcohol-exposure-in-male-and-female-rats
#6
Eva M Marco, Sara Peñasco, María-Donina Hernández, Anabel Gil, Erika Borcel, Marta Moya, Elena Giné, José Antonio López-Moreno, Consuelo Guerri, Meritxell López-Gallardo, Fernando Rodríguez de Fonseca
Alcohol is a serious public health concern that has a differential impact on individuals depending upon age and sex. Patterns of alcohol consumption have recently changed: heavy episodic drinking-known as binge-drinking-has become most popular among the youth. Herein, we aimed to investigate the consequences of intermittent adolescent alcohol consumption in male and female animals. Thus, Wistar rats were given free access to ethanol (20% in drinking water) or tap water for 2-h sessions during 3 days, and for an additional 4-h session on the 4th day; every week during adolescence, from postnatal day (pnd) 28-52...
2017: Frontiers in Behavioral Neuroscience
https://www.readbyqxmd.com/read/29229648/phosphorylation-of-the-unique-c-terminal-tail-of-the-alpha-isoform-of-the-scaffold-protein-sh2b1-controls-the-ability-of-sh2b1alpha-to-enhance-nerve-growth-factor-function
#7
Ray M Joe, Anabel Flores, Michael E Doche, Joel M Cline, Erik S Clutter, Paul B Vander, Heimo Riedel, Lawrence S Argetsinger, Christin Carter-Su
The scaffold protein SH2B1, a major regulator of body weight, is recruited to the receptors of multiple cytokines and growth factors, including nerve growth factor (NGF). The β isoform, but not the α isoform, of SH2B1 greatly enhances NGF-dependent neurite outgrowth of PC12 cells. Here we asked how the unique C-terminal tails of the α and β isoforms modulate SH2B1 function. We compared the actions of SH2B1α and SH2B1β to those of the N-terminal 631 amino acids shared by both isoforms. In contrast to the β-tail, the α-tail inhibited the ability of SH2B1 to both cycle through the nucleus and enhance NGF-mediated neurite outgrowth, gene expression, phosphorylation of Akt and PLCγ and autophosphorylation of the NGF receptor TrkA...
December 11, 2017: Molecular and Cellular Biology
https://www.readbyqxmd.com/read/29211267/-new-considerations-on-the-health-of-the-persons-with-intellectual-developmental-disorders
#8
Anabel Folch-Mas, María José Cortés-Ruiz, Luis Salvador-Carulla, Natalia Kazah-Soneyra, Marcia Irazábal-Giménez, Silvia Muñoz-Lorente, Javier Tamarit-Cuadrado, Rafael Martínez-Leal
Recent literature indicates that people with Disorders of Intellectual Development (DID) experience health disparities in the pathologies that they present, and a worst access to health care. However, current evidence-based knowledge is still sparse outside the Anglo-Saxon countries. The POMONA-I and POMONA-II European projects aimed to collect information on the health status of people with DID in Europe. The POMONA-ESP project in Spain is meant to collect health information in a wide and representative sample of persons with DID...
July 2017: Salud Pública de México
https://www.readbyqxmd.com/read/29211260/health-profiles-in-people-with-intellectual-developmental-disorders
#9
Anabel Folch-Mas, María José Cortés-Ruiz, Paloma Vicens Calderón, Rafael Martínez-Leal
OBJECTIVE: To better understand the health profiles of people with intellectual disability (ID), focusing on the variables that are associated with a poorer health status. MATERIALS AND METHODS: Data were collected from the Survey on Disability, Personal Autonomy and Dependency (EDAD 2008) of the Spanish National Statistics Institute (INE). The health data of 2840 subjects with IDD were analyzed in order to verify the impact of different variables on their health profiles...
July 2017: Salud Pública de México
https://www.readbyqxmd.com/read/29176871/effect-of-radiotherapy-on-activity-and-concentration-of-serum-paraoxonase-1-in-breast-cancer-patients
#10
Meritxell Arenas, Anabel García-Heredia, Noemí Cabré, Fedra Luciano-Mateo, Anna Hernández-Aguilera, Sebastià Sabater, Marta Bonet, Marina Gascón, Salvador Fernández-Arroyo, Isabel Fort-Gallifa, Jordi Camps, Jorge Joven
Paraoxonase-1 (PON1) is an intra-cellular antioxidant enzyme found also in the circulation associated with high-density lipoproteins. The activity of this enzyme has been shown to be decreased in breast cancer (BC) patients. The aims of our study were to investigate the changes produced by radiotherapy (RT) on activity and concentration of serum PON1 in BC patients, and to evaluate the observed variations in relation to clinical and pathological characteristics of patients and tumors, and the response to treatment...
2017: PloS One
https://www.readbyqxmd.com/read/29175158/multi-modal-potentiation-of-oncolytic-virotherapy-by-vanadium-compounds
#11
Mohammed Selman, Christopher Rousso, Anabel Bergeron, Hwan Hee Son, Ramya Krishnan, Nader A El-Sayes, Oliver Varette, Andrew Chen, Fabrice Le Boeuf, Fanny Tzelepis, John C Bell, Debbie C Crans, Jean-Simon Diallo
Oncolytic viruses (OV) are an emerging class of anticancer bio-therapeutics that induce antitumor immunity through selective replication in tumor cells. However, the efficacy of OVs as single agents remains limited. We introduce a strategy that boosts the therapeutic efficacy of OVs by combining their activity with immuno-modulating, small molecule protein tyrosine phosphatase inhibitors. We report that vanadium-based phosphatase inhibitors enhance OV infection in vitro and ex vivo, in resistant tumor cell lines...
October 24, 2017: Molecular Therapy: the Journal of the American Society of Gene Therapy
https://www.readbyqxmd.com/read/29164937/opening-remarks-during-the-42nd-annual-nahn-conference
#12
Anabell Castro Thompson
No abstract text is available yet for this article.
September 2017: Hispanic Health Care International: the Official Journal of the National Association of Hispanic Nurses
https://www.readbyqxmd.com/read/29148370/phylogenetic-characterization-of-crimean-congo-hemorrhagic-fever-virus-spain
#13
Eva Ramírez de Arellano, Lourdes Hernández, M José Goyanes, Marta Arsuaga, Ana Fernández Cruz, Anabel Negredo, María Paz Sánchez-Seco
Two cases of Crimean-Congo hemorrhagic fever were reported in Spain during 2016. We obtained the virus from a patient sample and characterized its full genomic sequence. Phylogenetic analysis indicated that the virus corresponds to the African genotype III, which includes viruses previously found in West and South Africa.
December 2017: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/29143783/metformin-potentiates-the-benefits-of-dietary-restraint-a-metabolomic-study
#14
Marta Riera-Borrull, Anabel García-Heredia, Salvador Fernández-Arroyo, Anna Hernández-Aguilera, Noemí Cabré, Elisabet Cuyàs, Fedra Luciano-Mateo, Jordi Camps, Javier A Menendez, Jorge Joven
Prevention of the metabolic consequences of a chronic energy-dense/high-fat diet (HFD) represents a public health priority. Metformin is a strong candidate to be incorporated in alternative therapeutic approaches. We used a targeted metabolomic approach to assess changes related to the multi-faceted metabolic disturbances provoked by HFD. We evaluated the protective effects of metformin and explored how pro-inflammatory and metabolic changes respond when mice rendered obese, glucose-intolerant and hyperlipidemic were switched to diet reversal with or without metformin...
October 28, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29124279/up-front-pet-ct-changes-treatment-intent-in-patients-with-head-and-neck-squamous-cell-carcinoma
#15
Max Rohde, Anne L Nielsen, Jørgen Johansen, Jens A Sørensen, Anabel Diaz, Jon T Asmussen, Oke Gerke, Anders Thomassen, Niels Gyldenkerne, Helle Døssing, Kristine Bjørndal, Poul Flemming Høilund-Carlsen, Christian Godballe
PURPOSE: In patients with newly diagnosed head and neck squamous cell carcinoma (HNSCC), we wanted to examine the differences in overall treatment decisions, i.e. curative versus palliative treatment intent, reached by a multidisciplinary team conference (MDTC) based on 18F-fluoro-deoxy-glucose-positron emission tomography/computed tomography (PET/CT) or chest X-ray + MRI of the head and neck (CXR/MRI). PATIENTS AND METHODS: This was a prospective blinded cohort study based on paired data...
November 10, 2017: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/29117172/corrigendum-host-dna-released-by-netosis-promotes-rhinovirus-induced-type-2-allergic-asthma-exacerbation
#16
Marie Toussaint, David J Jackson, Dawid Swieboda, Anabel Guedán, Theodora-Dorita Tsourouktsoglou, Yee Man Ching, Coraline Radermecker, Heidi Makrinioti, Julia Aniscenko, Michael R Edwards, Roberto Solari, Frédéric Farnir, Venizelos Papayannopoulos, Fabrice Bureau, Thomas Marichal, Sebastian L Johnston
This corrects the article DOI: 10.1038/nm.4332.
November 7, 2017: Nature Medicine
https://www.readbyqxmd.com/read/29107331/force-triggers-yap-nuclear-entry-by-regulating-transport-across-nuclear-pores
#17
Alberto Elosegui-Artola, Ion Andreu, Amy E M Beedle, Ainhoa Lezamiz, Marina Uroz, Anita J Kosmalska, Roger Oria, Jenny Z Kechagia, Palma Rico-Lastres, Anabel-Lise Le Roux, Catherine M Shanahan, Xavier Trepat, Daniel Navajas, Sergi Garcia-Manyes, Pere Roca-Cusachs
YAP is a mechanosensitive transcriptional activator with a critical role in cancer, regeneration, and organ size control. Here, we show that force applied to the nucleus directly drives YAP nuclear translocation by decreasing the mechanical restriction of nuclear pores to molecular transport. Exposure to a stiff environment leads cells to establish a mechanical connection between the nucleus and the cytoskeleton, allowing forces exerted through focal adhesions to reach the nucleus. Force transmission then leads to nuclear flattening, which stretches nuclear pores, reduces their mechanical resistance to molecular transport, and increases YAP nuclear import...
October 25, 2017: Cell
https://www.readbyqxmd.com/read/29090506/-minmax-a-versatile-tool-for-calculating-and-comparing-synonymous-codon-usage-and-its-impact-on-protein-folding
#18
Anabel Rodriguez, Gabriel Wright, Scott Emrich, Patricia L Clark
Most amino acids can be encoded by more than one synonymous codon, but these are rarely used with equal frequency. In many coding sequences the usage patterns of rare versus common synonymous codons is non-random and under selection. Moreover, synonymous substitutions that alter these patterns can have a substantial impact on the folding efficiency of the encoded protein. This has ignited broad interest in exploring synonymous codon usage patterns. For many protein chemists, biophysicists and structural biologists, the primary motivation for codon analysis is identifying and preserving usage patterns most likely to impact high-yield production of functional proteins...
November 1, 2017: Protein Science: a Publication of the Protein Society
https://www.readbyqxmd.com/read/29081264/health-status-of-copd-patients-undergoing-pulmonary-rehabilitation-a-comparative-responsiveness-of-the-cat-and-sgrq
#19
Anabel Sciriha, Stephen Lungaro-Mifsud, Josianne Scerri, Rosalie Magro, Liberato Camilleri, Stephen Montefort
The St. George's Respiratory Questionnaire (SGRQ) and chronic obstructive pulmonary disease (COPD) assessment test (CAT) are the measures used to assess health status. This study aims to examine the responsiveness of these tools by severity of dyspnoea category in patients with COPD. Forty-nine COPD patients who underwent a 12-week pulmonary rehabilitation (PR) programme were assessed at baseline, 12 weeks and at 28-week follow-up. Patients were categorized into two groups by severity of dyspnoea category (i...
November 2017: Chronic Respiratory Disease
https://www.readbyqxmd.com/read/29078763/prevalence-of-musculoskeletal-disorders-among-school-teachers-from-urban-and-rural-areas-in-chuquisaca-bolivia-a-cross-sectional-study
#20
María Teresa Solis-Soto, Anabel Schön, Angel Solis-Soto, Manuel Parra, Katja Radon
BACKGROUND: Musculoskeletal disorders (MSD) are important health problems in working populations. The study aimed to determine the prevalence of MSD among school teachers from urban and rural areas in Chuquisaca, Bolivia. METHODS: A cross-sectional study was conducted in 60 randomly selected schools. In total, 1062 teachers were invited to participate (response 58%). The Spanish version of the Standardized Nordic questionnaire was used assessing the 12-months and 7-days prevalence of MSD as well as the 12-months prevalence of work limiting pain...
October 27, 2017: BMC Musculoskeletal Disorders
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