Read by QxMD icon Read

Verapamil sensitive ventricular tachycardia

Ichiro Watanabe, Leonard S Gettes
Ca++ -channel antagonist verapamil and ATP-sensitive K+ -channel opener pinacidil are known to decrease the rise in extracellular K+ ([K+ ]e ) level and pH (pHe ) that occurs during reversible acute myocardial ischemia and to lessen the accompanying activation delay. Verapamil is also known to decrease the incidence of ventricular tachycardia (VT)/fibrillation (VF) during acute myocardial ischemia; however, the effects of ATP-sensitive K+ -channel opener on the incidence of VT/VF are controversial. We studied, in an in vivo pig model, the effects of verapamil and pinacidil on the changes in [K+ ]e level and pHe , local activation, and the incidence of VT/VF during 60 minutes of ischemia...
May 9, 2018: International Heart Journal
Minori Morita
A 32-year-old pregnant woman with verapamil sensitive ventricular tachycardia underwent elective caesarean section. She received catheter ablation for frequent tachycardia, but ventricular tachycardia appeared. In the operating room, a defibrillator pad was placed on her chest for external defibrillation, with A-line in a left radial artery. General anesthesia was started with rapid sequence induction. The anesthetic course was uneventful, and the infant showed no complication during the perioperative period...
May 2017: Masui. the Japanese Journal of Anesthesiology
Hiroshi Kawakami, Takeshi Aiba, Kohei Ishibashi, Ikutaro Nakajima, Mitsuru Wada, Tsukasa Kamakura, Yuko Inoue, Koji Miyamoto, Hideo Okamura, Satoshi Nagase, Takashi Noda, Yoshihiro Kokubo, Yoshihiro Miyamoto, Satoshi Yasuda, Shiro Kamakura, Kengo Kusano
BACKGROUND: Verapamil-sensitive idiopathic left ventricular tachycardia (verapamil-ILVT) is thought to be due to a reentry within the LV fascicular system. Radiofrequency catheter ablation (RFCA) is effective for elimination of the VT; however, a long-term prognosis of patients with verapamil-ILVT is still unclear. METHODS AND RESULTS: Eighty consecutive verapamil-ILVT patients (62 men, 31 ± 12 years of age, LVEF: 65 ± 4%) were enrolled. Seventy-six (95%) cases of VT involved right bundle branch block and left axis deviation...
March 2018: Journal of Cardiovascular Electrophysiology
Yuki Komatsu, Akihiko Nogami, Kenji Kurosaki, Itsuro Morishima, Keita Masuda, Tomoya Ozawa, Takashi Kaneshiro, Yuichi Hanaki, Yasutoshi Shinoda, Ahmed Karim Talib, Shinya Kowase, Yukio Sekiguchi, Kazutaka Aonuma
BACKGROUND: Verapamil-sensitive fascicular ventricular tachycardia (FVT) has been demonstrated to be a reentrant mechanism using the Purkinje network as a part of its reentrant circuit. Although the papillary muscles (PMs) are implicated in arrhythmogenic structure, reentrant FVT originating from the PMs has not been well defined. METHODS AND RESULTS: We studied 13 patients in whom FVT was successfully eliminated by ablation at the posterior PMs (n=8; PPM-FVT) and anterior PMs (n=5; APM-FVT)...
March 2017: Circulation. Arrhythmia and Electrophysiology
Ahmed Karim Talib, Akihiko Nogami
The presence of structural heart disease does not exclude fascicular ventricular tachycardia (VT), especially if the VT is verapamil sensitive. An empirical anatomic approach is effective when fascicular VT is noninducible or if diastolic Purkinje potential (P1) cannot be recorded during VT mapping. Pace mapping at the successful ablation site is usually not effective because selective pacing of P1 is difficult and there is an antidromic activation of the proximal P1 potential.
March 2016: Cardiac Electrophysiology Clinics
Hiroshi Taniguchi, Yoshinori Kobayashi, Mitsunori Maruyama, Norishige Morita, Meiso Hayashi, Yasushi Miyauchi, Wataru Shimizu
BACKGROUND: It is unclear whether false tendons (FTs) are a substantial part of the reentry circuit of verapamil-sensitive idiopathic left ventricular tachycardia (ILVT). This study aimed to prove the association between FTs and the slow conduction zone by evaluating the electro-anatomical relationship between the so-called diastolic Purkinje (Pd) potentials and FTs using an electro-anatomical mapping (EAM) system (CARTO). METHODS: The 1st protocol evaluated the spatial distribution of Pd and presystolic Purkinje (Pp) potentials in 6 IVLT patients using a conventional CARTO system...
October 2015: Journal of Arrhythmia
Paul Puie, Gabriel Cismaru, Lucian Muresan, Radu Rosu, Mihai Puiu, Marius Andronache, Gabriel Gusetu, Roxana Matuz, Petru-Adrian Mircea, Dana Pop, Dumitru Zdrenghea
Left ventricular posterior fascicular tachycardia (LVPFT) is an idiopathic form of VT characterized by right bundle branch block morphology and left axis deviation. The mechanism of LPFVT is thought to be localized reentry close to the posterior fascicle. We present the case of a 24-year-old medical student who was admitted to the emergency department complaining of palpitations. The ECG showed an aspect suggestive of LVPFT. Vagal maneuvers, adenosine and i.v. Metoprolol were ineffective in terminating the arrhythmia...
September 17, 2015: European Journal of Medical Research
Gurumurthy Hiremath, Walter Li, Rhonda Foltz, Arup Roy-Burman, Mark Cocalis, Ronn E Tanel
Idiopathic left ventricular tachycardia of the Belhassen type is rare in infants. We present a 6-month-old infant girl with a wide-complex tachycardia with right bundle branch block QRS morphology, a superior axis, and atrioventricular dissociation, consistent with a left anterior fascicular tachycardia. Initial echocardiogram revealed depressed ventricular function. The tachycardia was unresponsive to therapeutic trials of adenosine, esmolol, procainamide, and lidocaine. There was brief conversion of the tachycardia to sinus rhythm with transesophageal atrial overdrive pacing, suggesting a reentrant mechanism of the arrhythmia...
January 2015: Pediatric Emergency Care
Xiao-yan Liu, Wei Wei, Jian-min Chu, Le-xin Wang, Ying-jie Zhao, Jing Wang, Jie-lin Pu, Shu Zhang
OBJECTIVES: The variation of the substrates of verapamil-sensitive idiopathic left ventricular tachycardia (ILVT) was not understood. The purpose of this study was to investigate the variation of electroanatomic substrate [slow conduction zone (SCZ) and left ventricular conduction system (LVCS)] in ILVT and control individuals and markers of successful ablation. METHODS: Electroanatomical mapping was performed during sinus rhythm in 20 ILVT patients and 26 control individuals with paroxysmal supraventricular tachycardia...
August 2014: Journal of Cardiovascular Medicine
Kaoru Okishige, Harumizu Sakurada, Yuka Mizusawa, Yasuteru Yamauchi, Seiji Fukamizu, Hideshi Aoyagi, Yoshifumi Okano, Koji Azegami, Tetsuo Sasano, Kenzo Hirao
INTRODUCTION: Macro-reentrant ventricular tachycardias (VT) utilizing the bundle branches and Purkinje fibers have been reported as verapamil sensitive VT (idiopathic left VT), bundle branch reentrant VT (BBRT) and inter-fascicular reentrant tachycardia (inter-fascicular VT). However, diagnostic confusion exists with these VTs due to the difficulty in differentiating between them with conventional electrophysiological (EP) studies. The aim of this study was to clarify the EP and anatomical entity of inter-fascicular VT, and provide successful methods for the radio frequency catheter ablation (RFCA) of inter-fascicular VT...
October 2014: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
James E Ip, Christopher F Liu, George Thomas, Jim W Cheung, Steven M Markowitz, Bruce B Lerman
BACKGROUND: Based on the current understanding of cardiac conduction system development and the observation that arrhythmogenic foci can originate in areas near the atrioventricular annuli, we hypothesized that focal annular tachycardias, whether atrial or ventricular, share a common mechanism. We, therefore, prospectively evaluated this hypothesis in patients with sustained atrial and ventricular tachycardia originating from the peri-tricuspid and mitral annuli. METHODS AND RESULTS: Forty-nine consecutive patients with sustained, focal annular tachycardia comprised the study group...
June 2014: Circulation. Arrhythmia and Electrophysiology
Zhi-Qiang Ying, Miao-Yan Chen
Isolated left ventricular noncompaction (IVNC) is a rare congenital form of cardiomyopathy. Verapamil-sensitive fascicular ventricular tachycardia is a rare arrhythmogenic condition characterized by a right bundle-branch block pattern and left-axis deviation with a relatively narrow QRS complex. We herein present the case of a patient with IVNC who presented with verapamil-sensitive fascicular ventricular tachycardia.
2014: Internal Medicine
István Koncz, Zsolt Gurabi, Bence Patocskai, Brian K Panama, Tamás Szél, Dan Hu, Hector Barajas-Martínez, Charles Antzelevitch
Early repolarization pattern in the ECG has been associated with increased risk for ventricular tachycardia/fibrillation (VT/VF), particularly when manifest in inferior leads. This study examines the mechanisms underlying VT/VF in early repolarization syndrome (ERS). Transmembrane action potentials (APs) were simultaneously recorded from 2 epicardial sites and 1 endocardial site of coronary-perfused canine left-ventricular (LV) wedge preparations, together with a pseudo-ECG. Transient outward current (Ito) was recorded from epicardial myocytes isolated from the inferior and lateral LV of the same heart...
March 2014: Journal of Molecular and Cellular Cardiology
Tullio Morgera, Enzo Hrovatin, Carmine Mazzone, Franco Humar, Marzia De Biasio, Alessandro Salvi
AIMS: Ventricular tachycardia spreading from the anterior or posterior division of the left bundle branch is generally called fascicular tachycardia (FT). We will present our experience with FT, a type of ventricular tachycardia not necessarily implying the absence of heart disease and/or sensitivity to selective antiarrhythmic drugs, but only particular routes of left ventricular depolarization. METHODS: Since 1981 we have had the opportunity to study 10 cases of FT (nine men and one woman; aged 28-77 years, mean ± SD 55 ± 18...
November 2013: Journal of Cardiovascular Medicine
Suguru Nishiuchi, Akihiko Nogami, Shigeto Naito
A 36-year-old male presented with verapamil-sensitive narrow QRS tachycardia. The patient underwent the catheter ablation of common idiopathic left fascicular ventricular tachycardia (ILVT) 2 years ago. During narrow QRS tachycardia, the diastolic and presystolic potentials (P1 and P2) were recorded at the left septum. Activation sequences of P1 and P2 were opposite from those in common ILVT. Entrainment of P1 at the upper septum exhibited concealed fusion and S-QRS equal to P1-QRS. Radiofrequency current to P1 suppressed VT...
July 2013: Journal of Cardiovascular Electrophysiology
Yoshiaki Kaneko, Tadashi Nakajima, Tadanobu Irie, Masaki Ota, Toshimitsu Kato, Takafumi Iijima, Mio Tamura, Hiroaki Kobayashi, Masahiko Kurabayashi
We studied the electrophysiological characteristics of systolic (SP) and diastolic (DP) potentials recorded during sinus rhythm (SR) in the left interventricular septum of a 27 year-old woman presenting with verapamil-sensitive idiopathic left ventricular tachycardia (VT). During SR, and during VT, SP was activated from ventricular base-to-apex, and DP from apex-to-base. SP and DP were both detected at the site of successful ablation during SR, whereas during VT, DP was detected away from the earliest activation site...
2012: Cardiology Journal
Jianmin Chu, Yufa Sun, Yingjie Zhao, Wei Wei, Jing Wang, Xiaoyan Liu, Yuhe Jia, Kexiu Mao, Jielin Pu, Shu Zhang
BACKGROUND: Although idiopathic left ventricular tachycardia (ILVT) has been shown to possess a slow conduction zone (SCZ), the details of the electrophysiological and anatomic aspects are still not well understood. OBJECTIVE: We hypothesized that the SCZ can be identified using a 3-dimensional electroanatomic (EA) mapping system. METHODS: Ten patients with ILVT were mapped using a 3-dimensional electroanatomic (EA) mapping system. After a 3-dimensional endocardial geometry of the left ventricular was created, the conduction system with left Purkinje potential (PP) and the SCZ with diastolic potential (DP) in LV were mapped during sinus rhythm (SR) and ventricular tachycardia (VT) and were tagged as special landmarks in the geometry...
August 2012: Journal of Cardiovascular Electrophysiology
Yong Xie, Su-Rong Meng, Jian Peng, Ding-Li Xu, Chun-Feng Deng
OBJECTIVE: To assess the efficacy and safety of radiofrequency catheter ablation for verapamil-sensitive ventricular tachycardia (VT). METHODS: A total of 18 patients with a diagnosis of verapamil-sensitive VT were enrolled in this study. Radiofrequency catheter ablation was administered after underwent examinations on admission to rule out structural heart disease. the ablation catheter was placed around the left posterior intermediate septum and left anteroseptal in the left ventricular to searching for the Purkinje potential (P potential)...
September 13, 2011: Zhonghua Yi Xue za Zhi [Chinese medical journal]
Itsuro Morishima, Akihiko Nogami, Hideyuki Tsuboi, Takahito Sone
Left posterior fascicle and idiopathic Left VT. The left posterior fascicle may be a bystander of the circuit of verapamil-sensitive idiopathic left ventricular tachycardia. During ventricular tachycardia (VT), 3 sequences of potentials were seen at the left posterior septum: diastolic Purkinje potentials propagating from base to apex and presystolic left posterior fascicular potentials and systolic left ventricular (LV) myocardial potentials propagating in the reverse direction. Selective capture of the left posterior fascicle by the sinus beat did not affect the VT cycle length...
May 2012: Journal of Cardiovascular Electrophysiology
Andreas Metzner, Feifan Ouyang, Erik Wissner, Karl-Heinz Kuck
Monomorphic and polymorphic Purkinje-related ventricular tachycardias (VTs) may occur in patients with and without underlying structural heart disease. Monomorphic Purkinje-related VTs can be divided into different entities: verapamil-sensitive left fascicular VTs; bundle branch reentry tachycardias (BBRT); interfascicular VTs and focal Purkinje VTs. The most frequent fascicular VT is left posterior fascicular VT, characterized by macro-reentry within the posterior Purkinje network. However, the reentry may also be located in the anterior Purkinje network (left anterior fascicular VT)...
November 2011: Future Cardiology
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"