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Treadmill exercise testing

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https://www.readbyqxmd.com/read/28222572/effects-of-exercise-on-learning-and-memory-oxidative-stress-and-nnos-expression-in-marginal-division-of-striatum-of-the-ovariectomized-rats
#1
Jianmei Cui, Yanlan Guo, Wenyan Yang, Xingrui Zhao, Fang Yu, Wei Tang, Bianhua Pang, Xiaoyun Su
BACKGROUND: Since previous studies have shown that ovariectomy impairs memory and cognition, we investigated whether 8-week treadmill exercise would affect ovariectomy-induced memory deficits and explore the possible mechanisms of physical exercise influencing spatial learning and memory of the ovariectomized rats by detecting the rat's brain free radical metabolism and counting nNOS expression in marginal division of the striatum(MrD). METHODS: 40 female rats were assigned to one of the following groups: SHAM, SHAM+E, OVX and OVX+E group...
February 21, 2017: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/28219103/digoxin-induces-cardiac-hypertrophy-without-negative-effects-on-cardiac-function-and-physical-performance-in-trained-normotensive-rats
#2
Claodete Hasselstrom Neves, Ramires Alsamir Tibana, Jonato Prestes, Fabricio Azevedo Voltarelli, Andreo Fernando Aguiar, Gustavo Augusto Ferreira Mota, Sergio Luiz Borges de Sousa, Andre Soares Leopoldo, Ana Paula Lima Leopoldo, Andre Mueller, Danilo Henrique Aguiar, James Wilfred Navalta, Mario Mateus Sugizaki
Cardiotonic drugs and exercise training promote cardiac inotropic effects, which may affect training-induced cardiac adaptations. This study investigated the effects of long-term administration of digoxin on heart structure and function, and physical performance of rats submitted to high-intensity interval training (HIIT). Male Wistar rats, 60 days old, were divided into control (C), digoxin (DIGO), trained (T), and trained with digoxin (TDIGO). Digoxin was administered by gavage (30 µg/kg/day) for 75 days...
February 20, 2017: International Journal of Sports Medicine
https://www.readbyqxmd.com/read/28216412/sex-impacts-the-flow-mediated-dilation-response-to-acute-aerobic-exercise-in-older-adults
#3
Jeung-Ki Yoo, Michelle M Pinto, Han-Kyul Kim, Chueh-Lung Hwang, Jisok Lim, Eileen M Handberg, Demetra D Christou
There is growing evidence of sex differences in the chronic effect of aerobic exercise on endothelial function (flow-mediated dilation; FMD) in older adults, but whether there are sex differences also in the acute effect of aerobic exercise on FMD in older adults is unknown. The purpose of this study was to test the hypothesis that sex modulates the FMD response to acute aerobic exercise in older adults. Thirteen older men and fifteen postmenopausal women (67±1 vs. 65±2years, means±SE, P=0.6), non-smokers, free of major clinical disease, participated in this randomized crossover study...
February 16, 2017: Experimental Gerontology
https://www.readbyqxmd.com/read/28210957/forced-treadmill-exercise-prevents-spatial-memory-deficits-in-aged-rats-probably-through-the-activation-of-na-k-atpase-in-the-hippocampus
#4
Cláudia Vanzella, Eduardo Farias Sanches, Felipe Kawa Odorcyk, Fabrício Nicola, Janaína Kolling, Aline Longoni, Tiago Marcon Dos Santos, Angela Terezinha de Souza Wyse, Carlos Alexandre Netto
Regular physical activity has shown to improve the quality of life and to prevent age-related memory deficits. Memory processing requires proper regulation of several enzymes such as sodium-potassium adenosine triphosphatase (Na(+), K(+)-ATPase) and acetylcholinesterase (AChE), which have a pivotal role in neuronal transmission. The present study investigated the effects of a treadmill running protocol in young (3 months), mature (6 months) and aged (22 months) Wistar rats, on: (a) cognitive function, as assessed in the Water maze spatial tasks; (b) Na(+), K(+)-ATPase and AChE activities in the hippocampus following cognitive training alone or treadmill running combined with cognitive training...
February 16, 2017: Neurochemical Research
https://www.readbyqxmd.com/read/28207880/skeletal-muscle-metabolic-adaptations-to-endurance-exercise-training-are-attainable-in-mice-with-simvastatin-treatment
#5
William M Southern, Anna S Nichenko, Daniel D Shill, Corey C Spencer, Nathan T Jenkins, Kevin K McCully, Jarrod A Call
We tested the hypothesis that a 6-week regimen of simvastatin would attenuate skeletal muscle adaptation to low-intensity exercise. Male C57BL/6J wildtype mice were subjected to 6-weeks of voluntary wheel running or normal cage activities with or without simvastatin treatment (20 mg/kg/d, n = 7-8 per group). Adaptations in in vivo fatigue resistance were determined by a treadmill running test, and by ankle plantarflexor contractile assessment. The tibialis anterior, gastrocnemius, and plantaris muscles were evaluated for exercised-induced mitochondrial adaptations (i...
2017: PloS One
https://www.readbyqxmd.com/read/28197892/the-effect-of-acute-aerobic-exercise-on-hemostasis-in-obstructive-sleep-apnea
#6
Ryan A Martin, Courtney Strosnider, Gabrielle Giersch, Christopher J Womack, Trent A Hargens
PURPOSE: Individuals with obstructive sleep apnea (OSA) have an altered hemostatic balance; however, the exercise response is less described. The purpose of this study is to determine the hemostatic response after acute aerobic exercise in obstructive sleep apnea. METHODS: Eighteen males (nine OSA vs. nine controls) were recruited from the university and local community. Individuals with evidence of cardiovascular, pulmonary, or metabolic disease were excluded. An apnea-hypopnea index (AHI) of >5 was a criterion for OSA...
February 14, 2017: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/28185659/change-in-maximal-exercise-capacity-is-associated-with-survival-in-men-and-women
#7
Clinton A Brawner, Mouaz H Al-Mallah, Jonathan K Ehrman, Waqas T Qureshi, Michael J Blaha, Steven J Keteyian
OBJECTIVE: To describe the relationship between change in maximal exercise capacity (MEC) over time and risk of all-cause mortality separately in men and women. PATIENTS AND METHODS: Consecutive patients (n=10,854; mean ± SD age, 54±11 years; 43% women; 30% nonwhite) who completed 2 physician-referred exercise tests between January 2, 1991, and May 28, 2009, were identified from the Henry Ford Exercise Testing (FIT) Project. The MEC was quantified in metabolic equivalents of task (METs) calculated from peak workload on a treadmill and adjusted to the equivalent for a 50-year-old man...
February 6, 2017: Mayo Clinic Proceedings
https://www.readbyqxmd.com/read/28177723/fish-oil-and-treadmill-exercise-have-age-dependent-effects-on-episodic-memory-and-oxidative-state-of-the-hippocampus
#8
Patrícia Fortes Cavalcanti de Macêdo, Janatar Stella Vasconcelos de Melo, Laís Alves Ribeiro Costa, Glauber Rudá Feitoza Braz, Shirley M de Sousa, Cláudia J Lagranha, Manuella Batista-de-Oliveira Hornsby
There is a growing interest to better understand how lifestyle choices can improve memory functions. Treadmill exercise (Ex) and long-chain n-3 polyunsaturated fatty acids (PUFAs) found in fish oil (Fo) are able to stimulate hippocampal antioxidant defenses and improve memory. The aim was to test whether (Fo) and (Ex) can improve rat's performance on memory tasks and optimize hippocampal antioxidant state in an age-dependent manner. Therefore, young and adult rats were exercised and received (Fo) during four weeks...
January 9, 2017: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/28166650/the-effects-of-exercise-load-during-development-on-oxidative-stress-levels-and-antioxidant-potential-in-adulthood
#9
S Lee, J Hashimoto, T Suzuki, A Satoh
The objective of this study was to elucidate the impact of physical activity during the growth period as well as on oxidative stress and antioxidative potential in adulthood. The experimental animals used were four-week old male Wistar rats, which were randomly divided into three groups. The exercise loads were as follows: control (CON), treadmill exercise (TE), and jumping exercise (JE). The exercise was performed at the same time of day, at a frequency of five days per week, for eight weeks. Derivatives of reactive oxygen metabolites (d-ROSs) and biological antioxidant potential (BAP) were measured during periods of rest prior to commencement of the experiment and after the experiment...
February 6, 2017: Free Radical Research
https://www.readbyqxmd.com/read/28166185/heat-exposure-and-hypohydration-exacerbate-physiological-strain-during-load-carrying
#10
Elizabeth L Adams, Douglas J Casa, Robert A Huggins, Julie K DeMartini, Rebecca L Stearns, Rachel M Kennedy, Lindsay J DiStefano, Lawrence E Armstrong, Carl M Maresh
Heat exposure and hypohydration induce physiological and psychological strain during exercise; however, it is unknown if the separate effects of heat exposure and hypohydration are synergistic when co-occurring during loaded exercise. This study compared separate and combined effects of heat exposure and hypohydration on physiological strain, mood state, and visual vigilance during loaded exercise. Twelve males (mean±SD; age, 20±2 years; body mass, 74.0±8.2 kg; maximal oxygen uptake, 57.0±6.0 mLkg-1min-1) completed 4 trials under the following conditions: euhydrated temperate (EUT), hypohydrated temperate (HYT), euhydrated hot (EUH), and hypohydrated hot (HYH)...
February 1, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28166116/cerebral-blood-flow-responses-to-aquatic-treadmill-exercise
#11
Rhodri Parfitt, Marianne Y Hensman, Samuel J E Lucas
INTRODUCTION: Aquatic treadmills are used as a rehabilitation method for conditions such as spinal cord injury, osteoarthritis and stroke, and can facilitate an earlier return to exercise training for athletes. However, their effect on cerebral blood flow (CBF) responses has not been examined. We tested the hypothesis that aquatic treadmill exercise would augment CBF and lower heart rate compared to land-based treadmill exercise. METHODS: Eleven participants completed incremental exercise (crossover design) starting from walking pace [4 km/h, immersed to iliac crest (aquatic), 6 km/h (land)] and increasing 1 km/h every 2 min up to 10 km/h for aquatic (maximum belt speed) or 12 km/h for land...
February 4, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28163315/effects-of-topical-capsaicin-combined-with-moderate-exercise-on-insulin-resistance-body-weight-and-oxidative-stress-in-hypoestrogenic-obese-rats
#12
J M L Medina-Contreras, J Colado-Velázquez, N L Gómez-Viquez, P Mailloux-Salinas, I Perez-Torres, A Aranda-Fraustro, K Carvajal, G Bravo
BACKGROUND: Hypoestrogenic women are one of the most vulnerable groups for the development of obesity and its complications. Capsaicin and exercise have demonstrated to reduce body weight and to improve insulin sensitivity in different animal models, but it is unknown whether their combination could be useful in hypoestrogenic obese females. METHODS: We investigated whether topical capsaicin, exercise or their combination had better therapeutic effects in an obesity-hypoestrogenism model...
February 6, 2017: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/28161031/fmri-activity-during-associative-encoding-is-correlated-with-cardiorespiratory-fitness-and-source-memory-performance-in-older-adults
#13
Scott M Hayes, Jasmeet P Hayes, Victoria J Williams, Huiting Liu, Mieke Verfaellie
Older adults (OA), relative to young adults (YA), exhibit age-related alterations in functional Magnetic Resonance Imaging (fMRI) activity during associative encoding, which contributes to deficits in source memory. Yet, there are remarkable individual differences in brain health and memory performance among OA. Cardiorespiratory fitness (CRF) is one individual difference factor that may attenuate brain aging, and thereby contribute to enhanced source memory in OA. To examine this possibility, 26 OA and 31 YA completed a treadmill-based exercise test to evaluate CRF (peak VO2) and fMRI to examine brain activation during a face-name associative encoding task...
January 12, 2017: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
https://www.readbyqxmd.com/read/28157102/a-3-month-aerobic-training-program-improves-brain-energy-metabolism-in%C3%A2-mild%C3%A2-alzheimer-s-disease-preliminary-results-from-a-neuroimaging-study
#14
Christian-Alexandre Castellano, Nancy Paquet, Isabelle J Dionne, Hélène Imbeault, Francis Langlois, Etienne Croteau, Sébastien Tremblay, Mélanie Fortier, J Jacques Matte, Guy Lacombe, Tamás Fülöp, Christian Bocti, Stephen C Cunnane
BACKGROUND: Aerobic training has some benefits for delaying the onset or progression of Alzheimer's disease (AD). Little is known about the implication of the brain's two main fuels, glucose and ketones (acetoacetate), associated with thesebenefits. OBJECTIVE: To determine whether aerobic exercise training modifies brain energy metabolism in mild AD. METHODS: In this uncontrolled study, ten patients with mild AD participated in a 3-month, individualized, moderate-intensity aerobic training on a treadmill (Walking)...
February 1, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28153693/breathing-parameters-associated-to-two-different-external-nasal-dilator-strips-in-endurance-athletes
#15
Giancarlo Ottaviano, Andrea Ermolao, Ennio Nardello, Flavio Muci, Vittorio Favero, Marco Zaccaria, Lorenzo Favero
OBJECTIVE: The aim of the study was to investigate and compare the effects of two different external nasal dilator strips (ENDS) on nasal respiratory flow, maximal oxygen uptake (VO2max), nasal VO2max, time to exhaustion and subjective nasal obstruction in adult triathletes participating in exhaustive, controlled physical exercise tests. METHODS: Thirteen healthy triathletes without nasal symptoms were recruited and randomly tested in three different conditions: without ENDS, wearing the Breathe Right(®) dilator strip and wearing the Master-aid Roll-flex(®) strip...
January 30, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/28153628/evaluation-of-dose-response-relationship-between-smoking-load-and-cardiopulmonary-fitness-in-adult-smokers-a-cross-sectional-study
#16
V T Lauria, E F Sperandio, T L W de Sousa, W de Oliveira Vieira, M Romiti, A R de Toledo Gagliardi, R L Arantes, V Z Dourado
OBJECTIVE: To evaluate the dose-response relationship between smoking load and cardiopulmonary fitness, as measured with cardiopulmonary exercise testing (CPET), in adult smokers free of respiratory diseases. METHODS: After a complete clinical evaluation and spirometry, 95 adult smokers (35 men and 60 women) underwent CPET on a treadmill. RESULTS: The physiological responses during CPET showed lower cardiorespiratory fitness levels, regardless of smoking load, with a peak [Formula: see text] lower than 100% of the expected value and a lower maximum heart rate...
January 30, 2017: Revista Portuguesa de Pneumologia
https://www.readbyqxmd.com/read/28150476/nitrate-containing-beetroot-juice-reduces-oxygen-consumption-during-submaximal-exercise-in-low-but-not-high-aerobically-fit-male-runners
#17
Colin R Carriker, Roger A Vaughan, VanDusseldorp Trisha A, Johnson Kelly E, James J McCormick, Nathan H Cole, Ann L Gibson
Purpose: to examine the effect of a 4-day NO3- loading protocol on the submaximal oxygen cost of both low fit and high fit participants at five different exercise intensities. Methods: participants were initially assigned to a placebo (PL; negligible NO3-) or inorganic nitrate-rich (NR; 6.2 mmol nitrate/day) group; double-blind, placebo-controlled, crossover. Participants completed three trials (T1, T2 and T3). T1 included a maximal aerobic capacity (VO2max) treadmill test...
31, 2016: Journal of Exercise Nutrition & Biochemistry
https://www.readbyqxmd.com/read/28145667/acute-coronary-syndrome-diagnostic-evaluation
#18
Craig Barstow, Matthew Rice, Jonathan D McDivitt
Myocardial infarction (MI), a subset of acute coronary syndrome, is damage to the cardiac muscle as evidenced by elevated cardiac troponin levels in the setting of acute ischemia. Coronary artery disease is the leading cause of mortality in the United States. Chest pain is a common presentation in patients with MI; however, there are multiple noncardiac causes of chest pain, and the diagnosis cannot always be made based on initial presentation. The assessment of a possible MI includes evaluation of risk factors and presenting signs and symptoms, rapid electrocardiography, and serum cardiac troponin measurements...
February 1, 2017: American Family Physician
https://www.readbyqxmd.com/read/28144460/the-effect-of-aerobic-exercise-training-on-plasma-apelin-levels-and-pain-threshold-in-t1dm-rats
#19
Reza Delavar, Ali Heidarianpour
BACKGROUND: Diabetes mellitus (types 1 and 2) leads to secondary complications such as neuropathy, which reduce a patient's quality of life. Apelin and its receptor, APJ, have been shown to have antinociceptive effects and to decrease blood glucose levels. OBJECTIVES: The present experimental study was conducted in Iran and investigated the role of apelin, which is used to manage type 1 diabetes mellitus, during exercise training. MATERIALS AND METHODS: Male Wistar rats (n = 36) were assigned by simple random allocation to six groups (n = 6): non-diabetic (ND), diabetic (D), sedentary non-diabetic (SND), sedentary diabetic (SD), exercise non-diabetic (END), and exercise diabetic (ED)...
September 2016: Iranian Red Crescent Medical Journal
https://www.readbyqxmd.com/read/28142069/physical-exercise-ameliorates-mood-disorder-like-behavior-on-high-fat-diet-induced-obesity-in-mice
#20
Hye-Sang Park, Jae-Min Lee, Han-Sam Cho, Sang-Seo Park, Tae-Woon Kim
Obesity is associated with mood disorders such as depression and anxiety. The aim of this study was to investigate whether treadmill exercise had any benefits on mood disorder by high fat diet (HFD) induced obesity. Mice were randomly divided into four groups: control, control and exercise, high fat diet (HFD), and HFD and exercise. Obesity was induced by a 20-week HFD (60%). In the exercise groups, exercise was performed 6 times a week for 12 weeks, with the exercise duration and intensity gradually increasing at 4-week intervals...
January 5, 2017: Psychiatry Research
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