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Pediatric allergic rhinitis

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https://www.readbyqxmd.com/read/29667338/variation-in-the-tek-gene-is-not-associated-with-asthma-but-with-allergic-conjunctivitis
#1
L E Fodor, A Gézsi, Z Gál, A Nagy, A Kiss, A Bikov, C Szalai
The Tie2 receptor is an important player in angiogenesis. The Tie2 mRNA and protein are abundantly expressed in the lungs and the associated pathway also has an important role in the development and function of the eye. Tie2 is encoded by the TEK gene in humans. Recently, variations in the TEK gene have been found associated with asthma. The objective of the present study was to investigate whether variations in the TEK gene influenced the susceptibility to pediatric asthma and/or associated phenotypes like GINA status, viral- or exercise-induced asthma, allergic asthma, indoor, outdoor, inhalative allergies, IgE and eosonophil levels, allergic rhinitis and allergic conjunctivitis...
April 18, 2018: International Journal of Immunogenetics
https://www.readbyqxmd.com/read/29665973/epidemiology-of-pediatric-nickel-sensitivity-retrospective-review-of-north-american-contact-dermatitis-group-nacdg-data-1994-2014
#2
Erin M Warshaw, Kelly A Aschenbeck, Joel G DeKoven, Howard I Maibach, James S Taylor, Denis Sasseville, Donald V Belsito, Joseph F Fowler, Kathryn A Zug, Matthew J Zirwas, Anthony F Fransway, Vincent A DeLeo, James G Marks, Melanie D Pratt, Toby Mathias
BACKGROUND: Nickel is a common allergen responsible for allergic contact dermatitis. OBJECTIVE: To characterize nickel sensitivity in children and compare pediatric cohorts (≤5, 6-12, and 13-18 years). METHODS: Retrospective, cross-sectional analysis of 1894 pediatric patients patch tested by the North American Contact Dermatitis Group from 1994 to 2014. We evaluated demographics, rates of reaction to nickel, strength of nickel reactions, and nickel allergy sources...
April 14, 2018: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/29652870/surveillance-for-the-identification-of-cases-of-acute-respiratory-infection-by-enterovirus-d68-in-children-in-a-tertiary-level-care-hospital-during-2014-2016
#3
Ana Estela Gamiño-Arroyo, José Luis Sánchez-Huerta, Alicia Elhaín de la Garza-López, Israel Parra-Ortega, Noé Escobar-Escamilla, Edgar Mendieta-Condado, Fabiola Garcés-Ayala, Gisela Barrera-Badillo, José Ernesto Ramírez-González, José Alberto Díaz-Quiñonez, Daniela de la Rosa-Zamboni
Background: The reemergence of enterovirus D68 (EV-D68) infections in the United States was reported from August-October 2014 (691 cases). In Mexico, an outbreak at the National Institute of Respiratory Diseases was reported (24 cases). The results of epidemiological surveillance of Enterovirus sp. (EV) and other respiratory viruses in a national pediatric tertiary care level hospital are presented. Methods: Following the alert issued by the reemergence of EV-D68 in 2014, epidemiological surveillance -which only detected respiratory viruses by PCR in patients with influenza-like illness using nasopharyngeal swabs- expanded to include children with asthma exacerbation or acute respiratory distress...
2018: Boletín Médico del Hospital Infantil de México
https://www.readbyqxmd.com/read/29642713/house-dust-mite-sublingual-immunotherapy-for-pediatric-patients-with-allergic-asthma
#4
Jessika R Richards, Janice L Stumpf
OBJECTIVE: To review the published literature evaluating administration of house dust mite (HDM) sublingual immunotherapy (SLIT) in pediatric patients with allergic asthma. DATA SOURCES: PubMed database search (1966 to November 2017) using the search terms allergy, allergic rhinitis, asthma, allergic asthma, house dust mite, allergen immunotherapy, subcutaneous immunotherapy, sublingual immunotherapy, MK-8237, children, and pediatric. Package labeling and references from identified articles were also reviewed...
April 1, 2018: Annals of Pharmacotherapy
https://www.readbyqxmd.com/read/29520147/a-10-year-retrospective-study-of-alterative-aeroallergens-sensitization-spectrum-in-urban-children-with-allergic-rhinitis
#5
Li-Fen Yang, Liang-Ming Cai, Ming Li, Jin-Tao Liu, Zhao-Ni Wang, Wei-Hao Wang, Qin-Tai Yang, Zhuang-Gui Chen
Objective: To investigate the alterative spectrum and trends of aeroallergens sensitization in children with allergic rhinitis (AR) in Guangzhou, China in the past 10 years. Participants and methods: In this retrospective study, 4,111 children with complaints of nasal hyper-reactivity who visited the Pediatric Department and/or Otolaryngology Department from January 2007 to November 2016 were enrolled. Serum specific immunoglobulin E was measured and positive detection was made in 3,328 patients, who were, therefore, diagnosed with AR...
2018: Therapeutics and Clinical Risk Management
https://www.readbyqxmd.com/read/29484171/publication-trends-of-allergy-pediatric-allergy-and-immunology-and-clinical-and-translational-allergy-journals-a-mesh-term-based-bibliometric-analysis
#6
Daniel Martinho-Dias, Bernardo Sousa-Pinto, Júlio Botelho-Souza, António Soares, Luís Delgado, João Almeida Fonseca
We performed a MeSH term-based bibliometric analysis aiming to assess the publication trends of EAACI journals, namely Allergy, Pediatric Allergy and Immunology (PAI) (from 1990 to 2015) and Clinical and Translational Allergy (CTA) (from its inception in 2011 to 2015). We also aimed to discuss the impact of the creation of CTA in the publication topics of Allergy and PAI. We analysed a total of 1973 articles and 23,660 MeSH terms. Most MeSH terms in the three journals fell in the category of "basic immunology and molecular biology" (BIMB)...
2018: Clinical and Translational Allergy
https://www.readbyqxmd.com/read/29458220/incidence-of-autoimmune-and-related-disorders-after-resolution-of-endogenous-cushing-syndrome-in-children
#7
Christina Tatsi, Meg Keil, Charalampos Lyssikatos, Elena Belyavskaya, Constantine A Stratakis, Maya B Lodish
Glucocorticoids are widely used for immunosuppression in autoimmune diseases. After the resolution of hypercortisolemia, the immune system recovers allowing for autoimmune diseases to manifest. Here we investigated the presence of autoimmune and related diseases that developed after cure of endogenous Cushing syndrome (CS) in children. We identified 129 children who were diagnosed and successfully treated for endogenous CS at the National Institutes of Health from 1997 until 2017, and who were followed for at least 6 months after treatment...
February 19, 2018: Hormone and Metabolic Research, Hormon- und Stoffwechselforschung, Hormones et Métabolisme
https://www.readbyqxmd.com/read/29384116/anaphylaxis-in-a-food-allergy-outpatient-department-one-year-review
#8
R A Fernandes, F Regateiro, C Pereira, E Faria, J Pita, A Todo-Bom, I Carrapatoso
Background. Anaphylaxis is an acute, potentially fatal, multi-organ allergic reac-tion. Our aim was to characterize the population with food induced anaphylaxis followed over a one-year period. Methods. Retrospective analysis of clinical files of patients with food anaphylaxis observed in our food allergy consultation during 2016. Results. Sixty-two patients were included. In the pediatric group, the implicated allergens were cow's milk, egg and fish and in the adults' group, the commonest allergens were nuts and wheat...
March 2018: European Annals of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29382478/-the-counseling-of-nursing-decreases-symptomatology-and-relapses-in-pediatric-patients-with-allergic-rhinitis
#9
Laura Solís-Flores, Rosalinda Acuña-Rojas, Leobardo López-Medina, Guillermo Meléndez-Mier
BACKGROUND: Allergic rhinitis (AR) is considered to be a public health problem, therefore it is essential to test health education strategies such as nursing counseling (NC) aimed at population groups such as children with allergic rhinitis and their tutors. This study aimed to measure the health benefits of children with this disease for a year. METHODS: Longitudinal, randomized, comparative study with a sample of 100 pediatric patients of both sexes, aged 6 to 12 years, with diagnosis of allergic rhinitis, with counseling (study group) and without counseling (control group)...
September 2017: Boletín Médico del Hospital Infantil de México
https://www.readbyqxmd.com/read/29369414/molecular-sensitization-patterns-and-influence-of-molecular-diagnosis-in-immunotherapy-prescription-in-children-sensitized-to-both-grass-and-olive-pollen
#10
Ana Martínez-Cañavate Burgos, Javier Torres-Borrego, Ana Belén Molina Terán, Jose Luis Corzo, Blanca Esther Garcia, Ramón Rodríguez Pacheco, Carmen Moreno Aguilar, Ignacio Dávila
BACKGROUND: The overlapping grass and olive pollen seasons in Spain and the phenomenon of cross-reactivity can make it difficult to determine the true causative agent of seasonal allergic rhinitis when only skin prick tests with whole extracts are used. The aim of the GRAMOLE study was to determine sensitization patterns to the major grass and olive pollen allergens detected using specific recombinant IgE and to explore how this knowledge affected physicians' choice of allergen-specific immunotherapy...
January 25, 2018: Pediatric Allergy and Immunology
https://www.readbyqxmd.com/read/29338964/validation-of-the-children-s-sleep-habits-questionnaire-in-a-sample-of-greek-children-with-allergic-rhinitis
#11
A Mavroudi, E-A Chrysochoou, R J Boyle, G Trypsianis, I Xinias, D Cassimos, G Imvrios, M Katotomichelakis, A Karagiannidou, N Karantaglis, G Kourentas, J O Warner
BACKGROUND: Obstructive respiratory disorders, such as allergic rhinitis and asthma may impair sleep quality. The aim of this study is to validate the Children's Sleep Habits Questionnaire (CSHQ) for Greek children from 6 to 14 years of age. No validated tool has been developed so far to assess sleep disturbances in Greek school-aged children. METHODS: We examined the reliability and validity of the CSHQ in a sample of children with allergic rhinitis (AR) and a non-clinical population of parents of these children as a proxy measure of children's AR quality of life (QoL) as evaluated by the Pediatric Allergic Rhinitis Quality of Life (PedARQoL) questionnaire...
January 12, 2018: Allergologia et Immunopathologia
https://www.readbyqxmd.com/read/29315158/increased-incidence-of-obstructive-sleep-apnea-in-hospitalized-children-following-enterovirus-infection-a-nationwide-population-based-cohort-study
#12
Vincent Chin-Hung Chen, Yao-Hsu Yang, Ting-Yu Kuo, Kuo-You Huang, Yin-Cheng Huang, Yena Lee, Roger S McIntyre, Yu-Shu Huang, Chung-Yao Hsu
BACKGROUND: We report the first nationwide population-based cohort study using Taiwan's National Health Insurance Research Database on the association between enterovirus infection and the incidence of sleep disorders in a pediatric population. METHODS: Two matched groups of children under 18 years of age were included in the analyses for non-apneic sleep disorder and obstructive sleep apnea (OSA). Among them, 316 subjects were diagnosed with OSA during the surveillance period, including 182 in the EV infection group and 134 in the non-EV infection group...
January 8, 2018: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/29224752/incidence-and-factors-associated-with-revision-adenoidectomy-a-retrospective-study
#13
James Johnston, Murali Mahadevan, Richard G Douglas
INTRODUCTION: Adenoidectomy is one of the most commonly performed pediatric operations worldwide. There are a proportion of children who require revision adenoidectomy. Yet there is little in the literature about the incidence, associated factors and etiology of adenoidal regrowth. The aim of this retrospective cohort study was to determine incidence and factors associated with revision adenoidectomy. METHODS: An extraction of all hospital morbidity records belonging to patients under the age of 18 years who underwent one or more adenoidectomy procedures (with or without tonsillectomy) between January 1, 2000 and June 2016 at a tertiary care children's hospital was performed...
December 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29130983/prevalence-and-clinical-characteristics-of-local-allergic-rhinitis-in-children-sensitized-to-house-dust-mites
#14
Eun Kyo Ha, Min Sun Na, Shinhae Lee, Heysung Baek, Seung Jin Lee, Youn Ho Sheen, Young-Ho Jung, Kyung Suk Lee, Mi Ae Kim, Hye Mi Jee, Man Yong Han
OBJECTIVE: The prevalence of local allergic rhinitis (LAR) in nonatopic children remains unknown. This study aimed to determine the prevalence, clinical characteristics, and severity of LAR in children in comparison to classical allergic rhinitis (AR) and nonallergic rhinitis (NAR). STUDY DESIGN: A total of 145 children (aged 1-18 years) were enrolled and classified into 3 groups (AR, NAR, and LAR) based on a skin prick test (SPT) and a nasal provocation test (NPT) with house dust mite, i...
2017: International Archives of Allergy and Immunology
https://www.readbyqxmd.com/read/29115083/clinical-evaluation-of-techniques-for-measuring-nasal-specific-immunoglobulin-e-in-pediatric-patients
#15
Ji Young Ahn, Suk Jin Hong, Bong Seok Choi
Currently used methods for collecting nasal-specific immunoglobulin E (IgE) require administration of a large amount of saline into the nostrils, which is difficult in children. We designed two methods that are easy to use in children. We measured nasal-specific IgE and evaluated clinical characteristics of nasal-specific IgE in pediatric rhinitis. This study included 82 patients who visited Kyungpook National University Children's Hospital from December 2014 to July 2016 with rhinitis symptoms. Thirty patients used the spray method, and 52 patients used the swab method...
December 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/29049225/factors-related-to-pediatric-obstructive-sleep-apnea-hypopnea-syndrome-in-children-with-attention-deficit-hyperactivity-disorder-in-different-age-groups
#16
Jiali Wu, Meizhen Gu, Shumei Chen, Wei Chen, Kun Ni, Hongming Xu, Xiaoyan Li
This study aimed to retrospectively investigate the factors related to pediatric obstructive sleep apnea-hypopnea syndrome (OSAHS) with attention deficit hyperactivity disorder (ADHD) in children younger than 6 years and those older than 6 years.A total of 437 children who were hospitalized due to OSAHS between January 2014 and December 2014 were retrospectively reviewed. The children were further divided into OSAHS group and OSAHS + ADHD group. The general characteristics, OSA-18 quality of life, intention-hyperactivity score, and polysomnographic parameters (apnea-hypopnea index and the lowest oxygen saturation) were collected and compared between groups...
October 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29047174/pediatric-allergy-and-immunology-in-china
#17
REVIEW
Gary Wk Wong, Jing Li, Yi-Xiao Bao, Jiu-Yao Wang, Ting Fan Leung, Luan-Luan Li, Jie Shao, Xin-Yuan Huang, En-Mei Liu, Shen Kun-Ling, Chen Yu-Zhi
Over the past thirty years, China has enjoyed rapid economic development along with urbanization at a massive scale that the world has not experienced before. Such development has also been associated with a rapid rise in the prevalence of allergic disorders. Because of the large childhood population in the country, the burden of childhood allergic disorders has become one of the major challenges in the health care system. Among the Chinese centers participating in the International Study of Asthma and Allergies in Childhood clearly, the data showed a continuing rise in the prevalence of asthma, allergic rhinitis and atopic eczema...
October 19, 2017: Pediatric Allergy and Immunology
https://www.readbyqxmd.com/read/29018501/quality-of-life-in-pediatric-patients-with-allergic-rhinitis-treated-at-the-medical-clinic-of-integrated-education-unisul
#18
Mariana Dziekanski, Taíse de Freitas Marcelino
Introduction  Allergic rhinitis is a common disease among children and adolescents, reaching up to 40% of the population. During childhood, it is usually underdiagnosed because it has nonspecific symptoms. It has a negative impact on quality of life and may predispose to comorbidities. The diagnosis is clinical and treatment aims prevention. Objective  The objective of this study is to evaluate the quality of life in pediatric patients with allergic rhinitis. Methods This is an observational study with cross-sectional design...
October 2017: International Archives of Otorhinolaryngology
https://www.readbyqxmd.com/read/28941390/severe-forms-of-food-allergy
#19
REVIEW
Emanuel Sarinho, Maria das Graças Moura Lins
OBJECTIVES: To guide the diagnostic and therapeutic management of severe forms of food allergy. DATA SOURCES: Search in the Medline database using the terms "severe food allergy," "anaphylaxis and food allergy," "generalized urticaria and food allergy," and "food protein-induced enterocolitis syndrome" in the last ten years, searching in the title, abstract, or keyword fields. SUMMARY OF DATA: Food allergy can be serious and life-threatening...
November 2017: Jornal de Pediatria
https://www.readbyqxmd.com/read/28928804/efficacy-of-a-leukotriene-receptor-antagonist-for-pediatric-cedar-pollen-allergy-complicated-by-asthma
#20
Shigemi Yoshihara, Yutaka Kikuchi, Mari Saitou, Susumu Yanagawa, Noriko Kanno, Hiroshi Igarashi, Hironobu Fukuda, Akiko Iimura, Toshio Abe, Yumi Yamada, Tamotsu Andou, Osamu Arisaka
Leukotriene receptor antagonists (LTRAs) are identified as a monotherapy for asthma and allergic rhinitis; however, their use in children for treatment of these diseases has not been examined. Accordingly, the present study investigated the efficacy of pranlukast dry syrup for children with both pollinosis and asthma. The subjects were children receiving treatment for asthma who were also diagnosed with cedar pollen allergy. Patients were divided into a group that received continuous treatment with pranlukast (group A; n=20) and a group that commenced add-on treatment for pollinosis following the onset of symptoms (group B; n=20)...
October 2017: Experimental and Therapeutic Medicine
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