pneumonoconiosis

Heavy metals even at low concentrations can damage all systems in the human body from the cellular level by causing disruptions in DNA repair mechanisms, cell division and apoptosis. A 49-year-old man who had been working in the sanding and deburring department of a factory producing underground water pipes for 15 years, presented with complaints of effort dyspnea, cough and loss of strength in his left hand. Computed tomography of the lung revealed diffuse micronodular appearance in all zones in both lungs, subpleural nodule and bronchial dilatation...

Welding fumes (WFs) can cause occupational pneumonoconiosis and other diseases in workers. WFs have complex chemical composition and morphology depending on the welding conditions. The WF surface is a key factor affecting those diseases. The objective of this study was to establish an analytical method focused on characterizing individual WFs and welding slags (WSs) formed during CO2 arc welding processes for knowledge acquisition of risk assessment. Especially, the characterization was focused on the elemental distributions near the surfaces obtained using fluxing agents and size of the WFs...

Objective: To analyze the level and trend of respiratory disease mortality in China from 2002 to 2016. Methods: The standardized mortality rates were calculated based on the China health statistics yearbook (2003-2012) and China statistical yearbook of health and family planning (2013-2017) data released by the statistical information center of National health Commission of the People's Republic of China. Joinpoint model was used to calculate the standardized mortality rates (SMR), Annual percentage change (APC) and the average annual percentage change (AAPC) for standardized mortality rates...

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OBJECTIVE: To detect the inflammatory factors of induced sputum (IS) and whole lung lavage fluid in pneumonoconiosis patients and to explore the correlation between the inflammatory factors with pulmonary function. METHODS: The records of 45 cases of pneumonoconiosis patients were observed. All patients underwent lung function examination, sputum induction and massive whole lung lavage (WLL) sequentially through advance. IS and whole lung lavage fluid were collected respectively...

OBJECTIVE: To study the clinical characteristics and treatment method of pneumonoconiosis with spontaneous pneumothorax. METHODS: The clinical data of 55 cases with spontaneous pneumothorax were analyzed. RESULTS: Among these 55 cases, there were 19 cases with left side pneumothorax, 25 cases with right side pneumothorax and 11 cases with bilateral pneumothorax. The lungs of 17 cases were compressed to less than 20%, the lungs of 29 cases were compressed to 20% ∼ 50% and the lungs of 9 cases were compressed to more than 50%, 17 cases were treated conservatively, 7 cases were treated by thoracentesis, and 32 cases were treated by closed thoracic drainage, including 10 cases intrapleural injected with thrombin and PAMBA...

BACKGROUND: Biological monitoring of healthy workers exposed to hazardous dusts lack validated screening tools. Induced sputum (IS) cellular profile was compared with bronchoalveolar lavage fluid (BALF) profile in asbestos exposed workers in order to assess its usefulness in monitoring workers exposed to asbestos for a long period of time. METHODS: IS and BALF analysis was performed in 39 workers of a car brakes and clutches factory that uses chrysotile asbestos...

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OBJECTIVE: To investigate the changes of levels and clinic significance of serum soluble Fas (sFas) and soluble FasL (sFasL) in coal workers' pneumonoconiosis. METHODS: Serum levels of sFas and sFasL were determined in 52 patients with silicosis, 57 coal workers' pneumonoconiosis, 46 healthy underground coal workers' (the underground control group) and 40 healthy volunteers working on the ground (the ground control group) with a sandwich ELISA. RESULTS: Compared to the underground control and the ground control group, the serum levels of sFas and sFasL in the patients with silicosis and the coal workers' pneumonoconiosis were significantly higher (P < 0...

Progressive non-malignant lung disease (PNMLD) is a common cause of morbidity and mortality in the UK. In 1999, chronic lung disease--including chronic obstructive pulmonary disease (COPD), tuberculosis, pulmonary circulatory disease, pneumonoconiosis, sarcoidosis and cystic fibrosis--killed almost 39,000 (British Thoracic Society, 2000), while it is estimated that 600,000 people in the UK have COPD, the most common non-malignant lung disease (BTS, 2001).

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