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Pediatric depression

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https://www.readbyqxmd.com/read/29337001/antidepressant-treatment-duration-in-pediatric-depressive-and-anxiety-disorders-how-long-is-long-enough
#1
Elizabeth E Hathaway, John T Walkup, Jeffrey R Strawn
Anxiety and depressive disorders are common in the pediatric primary care setting, and respond to both psychotherapeutic and psychopharmacologic treatment. However, there are limited data regarding the optimal treatment duration. This article systematically reviews guidelines and clinical trial data related to antidepressant treatment duration in pediatric patients with depressive and anxiety disorders. The extant literature suggests 9-12 months of antidepressant treatment for youth with major depressive disorder...
January 11, 2018: Current Problems in Pediatric and Adolescent Health Care
https://www.readbyqxmd.com/read/29334854/the-association-between-premorbid-conditions-in-school-aged-children-with-prolonged-concussion-recovery
#2
Réjean M Guerriero, Karameh Kuemmerle, Michael J Pepin, Alex M Taylor, Robert Wolff, William P Meehan
The association between preexisting anxiety, depression, and/or neurodevelopmental disorders and symptom duration among younger children who sustain concussions is not well known. The authors conducted a prospective cohort study of 569 patients presenting to a pediatric neurology clinic with the diagnosis of concussion. The authors measured associations between symptom duration and premorbid conditions, as well as gender, age, mechanism of injury, and other factors. Premorbid conditions were common in both age groups...
February 2018: Journal of Child Neurology
https://www.readbyqxmd.com/read/29325731/pharmacogenomic-testing-in-child-and-adolescent-psychiatry-an-evidence-based-review
#3
Anna M Wehry, Laura Ramsey, Shane E Dulemba, Sarah A Mossman, Jeffrey R Strawn
Significant advances have been made in the application of pharmacogenomic testing for the treatment of patients with psychiatric disorders. Over the past decade, a number of studies have evaluated the utility of pharmacogenomic testing in pediatric patients with psychiatric disorders. The evidence base for pharmacogenomic testing in youth with depressive and anxiety disorders as well as attention/deficit hyperactivity disorder (ADHD) is reviewed in this article. General pharmacogenomic principles are summarized and functional polymorphisms in P450 enzymes (and associated metabolizer phenotypes), the serotonin transporter promoter polymorphisms, serotonin 2 A receptor genes (e...
January 8, 2018: Current Problems in Pediatric and Adolescent Health Care
https://www.readbyqxmd.com/read/29305113/developing-a-postpartum-depression-screening-and-referral-procedure-in-pediatric-primary-care
#4
Julee Waldrop, Alasia Ledford, Leslie Chandler Perry, Linda S Beeber
INTRODUCTION: Postpartum depression affects approximately 10% to 20% of mothers and impairs a mother's ability to engage with her child at an emotional and cognitive level, placing the child at greater risk for impaired development. Early diagnosis and management can reduce its negative impacts. Despite mothers being receptive to screening, screening rates are less than 50%. METHODS: This article provides an appraisal of the current state of the evidence on implementing screening for postpartum depression in pediatric primary care...
January 2, 2018: Journal of Pediatric Health Care
https://www.readbyqxmd.com/read/29304081/trajectories-of-aggressive-and-depressive-symptoms-in-male-and-female-overweight-children-do-they-share-a-common-path-or-do-they-follow-different-routes
#5
Luca Cerniglia, Silvia Cimino, Michela Erriu, Stanislav Jezek, Carlos A Almenara, Renata Tambelli
The prevalence of childhood overweight is a major social and public health issue, and primary assessment should focus on early and middle childhood, because weight gain in these phases constitutes a strong predictor of subsequent negative outcomes. Studies on community samples have shown that growth curves may follow linear or non-linear trajectories from early to middle childhood, and can differ based on sex. Overweight children may exhibit a combination of physiological and psychosocial issues, and several studies have demonstrated an association between overweight and internalizing/externalizing behavior...
2018: PloS One
https://www.readbyqxmd.com/read/29302747/cytokine-chemokine-and-bdnf-levels-in-medication-free-pediatric-patients-with-obsessive-compulsive-disorder
#6
Rukiye Çolak Sivri, Ayhan Bilgiç, İbrahim Kılınç
The aim of this study was to investigate whether the serum levels of IL-12, IL-17, TGFβ, TNF-alpha, sTNFR1, sTNFR2, IL-1β, CCL3, CCL24, CXCL8, and BDNF are associated with obsessive-compulsive disorder (OCD) in medication-free children. A total of 44 (22 boys/22 girls) medication-free children with OCD and 40 (23 boys/17 girls) healthy controls were included in this study. The severity of the OCD symptoms were assessed by the Children's Yale-Brown Obsessive-Compulsive Scale and the Maudsley Obsessive-Compulsive Inventory...
January 4, 2018: European Child & Adolescent Psychiatry
https://www.readbyqxmd.com/read/29301012/diagnosis-of-heroin-overdose-in-an-8-year-old-boy-reliable-contribution-of-toxicological-investigations
#7
M Soichot, S Julliand, J Filatriau, A Hurbain, E Bourgogne, A Mihoubi, H Gourlain, B Delhotal-Landes
Toxicological investigations are often required by clinicians in comatose patients with suspected poisoning. However, the usefulness of toxicological analyses to support a diagnosis of acute poisoning is debated among clinicians and the interpretation of laboratory tests is challenging given the wide diversity of analytical techniques available. We report the case of an 8-year-old boy who was admitted to an intensive care unit with severe respiratory depression and neurological impairment. In order to formulate appropriate hypothesizes about the diagnosis and circumstances of intoxication, clinicians consulted toxicologists for a comprehensive toxicological screening...
December 28, 2017: Journal of Analytical Toxicology
https://www.readbyqxmd.com/read/29300333/atomic-resolution-structures-of-human-bufaviruses-determined-by-cryo-electron-microscopy
#8
Maria Ilyas, Mario Mietzsch, Shweta Kailasan, Elina Väisänen, Mengxiao Luo, Paul Chipman, J Kennon Smith, Justin Kurian, Duncan Sousa, Robert McKenna, Maria Söderlund-Venermo, Mavis Agbandje-McKenna
Bufavirus strain 1 (BuV1), a member of the Protoparvovirus genus of the Parvoviridae, was first isolated from fecal samples of children with acute diarrhea in Burkina Faso. Since this initial discovery, BuVs have been isolated in several countries, including Finland, the Netherlands, and Bhutan, in pediatric patients exhibiting similar symptoms. Towards their characterization, the structures of virus-like particles of BuV1, BuV2, and BuV3, the current known genotypes, have been determined by cryo-electron microscopy and image reconstruction to 2...
January 4, 2018: Viruses
https://www.readbyqxmd.com/read/29283609/-miscarried-helping-in-adults-with-type-2-diabetes-helping-for-health-inventory-couples
#9
Rika Tanaka, Paula M Trief, Kasandra Scales, Ruth S Weinstock
OBJECTIVE: Family-partner support has been associated with better blood glucose control, self-care adherence, and quality of life in adult patients with Type 2 diabetes (T2D). "Miscarried helping" has described interactions between youth with chronic diseases and their family members, in which a family member is helpful, but efforts are perceived as negative by the patient. Miscarried helping has not, however, been measured in adults with diabetes, which was the purpose of our study. METHOD: Data from a randomized clinical trial (n = 268) were analyzed to establish the psychometric properties and correlates of an adaptation of a measure of miscarried helping developed in pediatric populations, for use with adults with T2D...
December 2017: Families, Systems & Health: the Journal of Collaborative Family Healthcare
https://www.readbyqxmd.com/read/29279324/age-at-menarche-depression-and-antisocial-behavior-in-adulthood
#10
Jane Mendle, Rebecca M Ryan, Kirsten M P McKone
BACKGROUND: Early pubertal timing in girls is one of the best-replicated antecedents of a range of mental health problems during adolescence, but few researchers have examined the duration of these effects. METHODS: We leverage a nationally representative sample (N = 7802 women) managed prospectively from adolescence over a period of ∼14 years to examine associations of age at menarche with depressive symptoms and antisocial behaviors in adulthood. RESULTS: Earlier ages at menarche were associated with higher rates of both depressive symptoms and antisocial behaviors in early-middle adulthood largely because difficulties that started in adolescence did not attenuate over time...
December 26, 2017: Pediatrics
https://www.readbyqxmd.com/read/29278434/intended-and-unintended-consequences-ethics-communication-and-prognostic-disclosure-in-pediatric-oncology
#11
Jonathan M Marron, Angel M Cronin, Tammy I Kang, Jennifer W Mack
BACKGROUND: The majority of patients desire all available prognostic information, but some physicians hesitate to discuss prognosis. The objective of the current study was to examine outcomes of prognostic disclosure among the parents of children with cancer. METHODS: The authors surveyed 353 parents of children with newly diagnosed cancer at 2 tertiary cancer centers, and each child's oncologist. Using multivariable logistic regression, the authors assessed associations between parental report of elements of prognosis discussions with the oncologist (quality of information/communication and prognostic disclosure) and potential consequences of these discussions (trust, hope, peace of mind, prognostic understanding, depression, and anxiety)...
December 26, 2017: Cancer
https://www.readbyqxmd.com/read/29277313/quality-of-life-and-mood-in-children-with-cystic-fibrosis-associations-with-sleep-quality
#12
Moya Vandeleur, Lisa M Walter, David S Armstrong, Philip Robinson, Gillian M Nixon, Rosemary S C Horne
BACKGROUND: We aimed to investigate the relationship between sleep quality, mood and health-related quality of life (HRQOL) in children with CF and controls. METHODS: Children (7-12years) and adolescents (13-18years) with CF and controls completed sleep evaluation: overnight oximetry and 14days of actigraphy. Age-appropriate questionnaires assessed mood (Children's Depression Inventory; CDI or Beck's Depression Inventory), HRQOL (CF Questionnaire-Revised; CFQ-R or PedsQL), and sleepiness (Pediatric Daytime Sleepiness Scale)...
December 22, 2017: Journal of Cystic Fibrosis: Official Journal of the European Cystic Fibrosis Society
https://www.readbyqxmd.com/read/29260883/the-quality-of-life-of-children-under-chiropractic-care-using-promis-25-results-from-a-practice-based-research-network
#13
Joel Alcantara, Andrea E Lamont, Jeanne Ohm, Junjoe Alcantara
OBJECTIVES: To characterize pediatric chiropractic and assess pediatric quality of life (QoL). DESIGN: A prospective cohort. Setting/Locations: Individual offices within a practice-based research network located throughout the United States. SUBJECTS: A convenience sample of children (8-17 years) under chiropractic care and their parents. EXPOSURE: Chiropractic spinal adjustments and adjunctive therapies. OUTCOME MEASURES: Survey instrument measuring sociodemographic information and correlates from the clinical encounter along with the Patient Reported Outcomes Measurement Information System (PROMIS)-25 to measure QoL (i...
December 20, 2017: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
https://www.readbyqxmd.com/read/29250653/integrative-clinico-biological-pharmacogenetic-neuroimagistic-neuroendocrinological-and-psychological-correlations-in-depressive-and-anxiety-disorders
#14
Lavinia Maria Hogea, Laura Alexandra Nussbaum, Daniela Veronica Chiriac, LuminiŢa Ştefania Ageu, Nicoleta Ioana Andreescu, Mirela Loredana Grigoraş, Roxana Folescu, Ana Cristina Bredicean, Maria Puiu, Elena Cecilia Ildikó Roşca, Mihaela Adriana Simu, Codrina Mihaela Levai
We approach the theme of modern treatment strategies, based on clinico-biological, pharmacogenetic, neuroimagistic, neuroendocrinological and psychological integrative correlations in the management of depressive and comorbid anxiety disorders. We target to evaluate the efficacy of the pharmacogenetic testing and the evolution, functioning of patients in correlation with specific neurobiological, neuroimagistic and neuroendocrinological markers. Our research was conducted between 2010-2016 on 80 children and adolescents with depressive and comorbid anxiety disorders - 40 children (G1 group), who benefited in choosing the pharmacotherapy from pharmacogenetic testing and 40 children without testing (G2 group)...
2017: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/29248202/clonidine-administration-during-intraoperative-monitoring-for-pediatric-scoliosis-surgery-effects-on-central-and-peripheral-motor-responses
#15
Pedro Calderón, Paul Deltenre, Ida Stany, Jean-Paul Kaleeta Maalu, Magali Stevens, Jean Lamoureux, Michel Bellemans, Sylvie Dujardin, Philippe Van der Linden, Bernard Dachy
OBJECTIVE: To study the effect of clonidine administrated as a co-analgesic during scoliosis surgery, on the neuromonitoring of spinal motor pathways. METHODS: Using standardized intraoperative monitoring, we compared the time course of peripherally and transcranially electrically evoked motor potentials (TcEMEPs) before and after injection of a single bolus of clonidine in children under total intravenous anesthesia (TIVA). MEP data were obtained from 9 patients and somatosensory evoked potentials (SSEPs) were obtained from 2 patients...
December 13, 2017: Neurophysiologie Clinique, Clinical Neurophysiology
https://www.readbyqxmd.com/read/29248034/health-outcomes-for-children-in-haiti-since-the-2010-earthquake-a-systematic-review
#16
Annie Dube, Madeline Moffatt, Colleen Davison, Susan Bartels
BACKGROUND: Haiti remains the poorest country in the Americas and one of the poorest in the world. Children in Haiti face many health concerns, some of which were exacerbated by the 2010 earthquake. This systematic review summarizes published research conducted since the 2010 earthquake, focusing on health outcomes for children in Haiti, including physical, psychological, and socioeconomic well-being. METHODS: A literature search was conducted identifying articles published from January 2010 through May 2016 related to pediatric health outcomes in Haiti...
December 18, 2017: Prehospital and Disaster Medicine
https://www.readbyqxmd.com/read/29243974/pediatric-cerebral-venous-sinus-thrombosis-or-compression-in-the-setting-of-skull-fractures-from-blunt-head-trauma
#17
David S Hersh, Nir Shimony, Mari L Groves, Gerald F Tuite, George I Jallo, Ann Liu, Tomas Garzon-Muvdi, Thierry A G M Huisman, Ryan J Felling, Joseph A Kufera, Edward S Ahn
OBJECTIVE Pediatric cerebral venous sinus thrombosis has been previously described in the setting of blunt head trauma; however, the population demographics, risk factors for thrombosis, and the risks and benefits of detection and treatment in this patient population are poorly defined. Furthermore, few reports differentiate between different forms of sinus pathology. A series of pediatric patients with skull fractures who underwent venous imaging and were diagnosed with intrinsic cerebral venous sinus thrombosis or extrinsic sinus compression is presented...
December 15, 2017: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/29242810/-her-life-rests-on-your-shoulders-doing-worry-as-emotion-work-in-the-care-of-children-with-diabetes
#18
Lisa Watt
Research on parents' caregiving experiences in the context of diabetes management have consistently shown that parents experience high levels of pediatric parenting stress, anxiety, depression, and general worry. However, how parents understand their worry is largely unexplored and little attention is paid to the work parents are already actively doing to manage their worry. Adopting Arlie Hochschild's concept of "emotion work" and Dorothy Smith's concept of "work," this article examines how parents engage in the emotion work of doing worry...
January 2017: Global Qualitative Nursing Research
https://www.readbyqxmd.com/read/29241842/functional-impact-of-congenital-hand-differences-early-results-from-the-congenital-upper-limb-differences-could-registry
#19
Donald S Bae, Maria F Canizares, Patricia E Miller, Peter M Waters, Charles A Goldfarb
PURPOSE: To characterize the functional, emotional, and social impact of congenital upper limb differences on affected children and families before treatment, using validated functional outcome instruments. METHODS: From June 2014 to March 2016, 586 children with congenital upper limb differences from 2 pediatric hospitals were enrolled in the Congenital Upper Limb Differences registry. Demographic, clinical, and radiographic data were collected, and diagnoses categorized according to the Oberg-Manske-Tonkin classification...
December 11, 2017: Journal of Hand Surgery
https://www.readbyqxmd.com/read/29240936/grit-illness-related-distress-and-psychosocial-outcomes-in-college-students-with-a-chronic-medical-condition-a-path-analysis
#20
Christina M Sharkey, Dana M Bakula, Amanda N Baraldi, Megan N Perez, Kristina I Suorsa, John M Chaney, Larry L Mullins
Objective: Adolescents and young adults (AYAs) with chronic medical conditions are at increased risk for a host of negative psychosocial outcomes, including depressive and anxious symptoms. Although studies have shown that illness appraisals (e.g., illness intrusiveness [II] and illness uncertainty [IU]) demonstrate consistent associations with such outcomes, few studies have examined positive factors that may relate to better psychosocial outcomes and appraisals. The present study evaluated grit (i...
December 12, 2017: Journal of Pediatric Psychology
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