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https://www.readbyqxmd.com/read/27883876/comprehensive-genomic-profiling-of-central-giant-cell-lesions-identifies-clinically-relevant-genomic-alterations
#1
Brett Bezak, Heidi Lehrke, Julia Elvin, Laurie Gay, David Schembri-Wismayer, Christopher Viozzi
PURPOSE: Comprehensive genomic profiling (CGP) can simultaneously detect clinically relevant genomic alterations (CRGAs) in hundreds of cancer-related genes and direct treatment toward patient-specific therapy options for many tumors. This pilot study aimed to use CGP to describe CRGAs present in central giant cell lesions (CGCLs) to characterize any possible underlying genomic drivers of CGCLs. MATERIALS AND METHODS: With institutional review board approval, electronic medical records were searched for patients with histologically confirmed CGCLs who underwent biopsy at Mayo Clinic from 2000 through 2014...
November 1, 2016: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/27865796/bletilla-striata-medicinal-uses-phytochemistry-and-pharmacological-activities
#2
REVIEW
Xirui He, Jiacheng Fang, Xiaoxiao Wang, Zefeng Zhao, Yu Chang, Hao Guo, Linhong Huang
ETHNOPHARMACOLOGICAL RELEVANCE: Bletilla striata (Thunb.) Reichb. f. (Orchidaceae), also known as Hyacinth Orchid and Baiji (Simplified Chinese: ), not only has been widely used for the treatment of hematemesis, hemoptysis, and traumatic bleeding due to the efficacy of arresting bleeding with astringent action, but also has been applied topically to overcome ulcers, sores, swellings, and chapped skin due to the efficacy of dispersing swelling and promoting tissue regeneration. Additional medical applications include the treatment of tuberculosis, malignant ulcers, hemorrhoids, anthrax, eye diseases, and silicosis...
November 16, 2016: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/27846927/enhanced-invitation-methods-and-uptake-of-health-checks-in-primary-care-randomised-controlled-trial-and-cohort-study-using-electronic-health-records
#3
Lisa McDermott, Alison J Wright, Victoria Cornelius, Caroline Burgess, Alice S Forster, Mark Ashworth, Bernadette Khoshaba, Philippa Clery, Frances Fuller, Jane Miller, Hiten Dodhia, Caroline Rudisill, Mark T Conner, Martin C Gulliford
BACKGROUND: A national programme of health checks to identify risk of cardiovascular disease (CVD) is being rolled out but is encountering difficulties because of low uptake. OBJECTIVE: To evaluate the effectiveness of an enhanced invitation method using the question-behaviour effect (QBE), with or without the offer of a financial incentive to return the QBE questionnaire, at increasing the uptake of health checks. The research went on to evaluate the reasons for the low uptake of invitations and compare the case mix for invited and opportunistic health checks...
November 2016: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/27830236/recent-worldwide-developments-in-ehealth-and-mhealth-to-more-effectively-manage-cancer-and-other-chronic-diseases-a-systematic-review
#4
J Lewis, P Ray, S-T Liaw
OBJECTIVES: This paper is a systematic literature review intended to gain an understanding of the most original, excellent, stateof- the-art research in the application of eHealth (including mHealth) in the management of chronic diseases with a focus on cancer over the past two years. METHOD: This review looks at peer-reviewed papers published between 2013 and 2015 and examines the background and trends in this area. It systematically searched peer-reviewed journals in databases PubMed, Proquest, Cochrane Library, Elsevier, Sage and the Institute of Electrical and Electronic Engineers (IEEE Digital Library) using a set of pre-defined keywords...
November 10, 2016: Yearbook of Medical Informatics
https://www.readbyqxmd.com/read/27808064/use-of-speech-to-text-technology-for-documentation-by-healthcare-providers
#5
REVIEW
Sima Ajami
Medical records are a critical component of a patient's treatment. However, documentation of patient-related information is considered a secondary activity in the provision of healthcare services, often leading to incomplete medical records and patient data of low quality. Advances in information technology (IT) in the health system and registration of information in electronic health records (EHR) using speechto- text conversion software have facilitated service delivery. This narrative review is a literature search with the help of libraries, books, conference proceedings, databases of Science Direct, PubMed, Proquest, Springer, SID (Scientific Information Database), and search engines such as Yahoo, and Google...
May 2016: National Medical Journal of India
https://www.readbyqxmd.com/read/27782832/factors-that-influence-the-implementation-of-e-health-a-systematic-review-of-systematic-reviews-an-update
#6
REVIEW
Jamie Ross, Fiona Stevenson, Rosa Lau, Elizabeth Murray
BACKGROUND: There is a significant potential for e-health to deliver cost-effective, quality health care, and spending on e-health systems by governments and healthcare systems is increasing worldwide. However, there remains a tension between the use of e-health in this way and implementation. Furthermore, the large body of reviews in the e-health implementation field, often based on one particular technology, setting or health condition make it difficult to access a comprehensive and comprehensible summary of available evidence to help plan and undertake implementation...
October 26, 2016: Implementation Science: IS
https://www.readbyqxmd.com/read/27772555/identifying-psychosocial-predictors-of-medication-non-adherence-following-acute-coronary-syndrome-a-systematic-review-and-meta-analysis
#7
Jacob Crawshaw, Vivian Auyeung, Sam Norton, John Weinman
OBJECTIVE: Medication non-adherence following acute coronary syndrome (ACS) is associated with poor clinical outcomes. A systematic review and meta-analysis were undertaken to identify psychosocial factors associated with medication adherence in patients with ACS. METHODS: A search of electronic databases (Cochrane Library, Medline, EMBASE, PsycINFO, Web of Science, International Pharmaceutical Abstracts, CINAHL, ASSIA, OpenGrey, EthOS and WorldCat) was undertaken to identify relevant articles published in English between 2000 and 2014...
November 2016: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/27708494/teleconsultation-and-clinical-decision-making-a-systematic-review
#8
Kolsoum Deldar, Kambiz Bahaadinbeigy, Seyed Mahmood Tara
BACKGROUND: The goal of teleconsultation is to omit geographical and functional distance between two or more geographically separated health care providers. The purpose of present study is to review and analyze physician-physician teleconsultations. METHOD: The PubMed electronic database was searched. The primary search was done on January 2015 and was updated on December 2015. A fetch and tag plan was designed by the researchers using an online Zotero library. RESULTS: 174 full-text articles of 1702 records met inclusion criteria...
July 16, 2016: Acta Informatica Medica: AIM
https://www.readbyqxmd.com/read/27575332/clinical-mutation-assay-of-tumors-new-developments
#9
Petr Starostik
Mutation detection in tumors started with classical cytogenetics as the method of choice more than 50 years ago. Karyotyping proved to be sensitive enough to detect deletions or duplications of large chromosome segments, and translocations. Over time, new techniques were developed to detect mutations that are much smaller in scope. The availability of Sanger sequencing and the invention of the PCR improved the discriminatory power of mutation detection to just one base change in the genomic DNA sequence. Techniques derived from PCR (allele-specific PCR, qPCR) and improved or modified sequencing methods (capillary electrophoresis, pyrosequencing) considerably increased the efficiency and sample throughput of mutation detection assays...
January 2017: Anti-cancer Drugs
https://www.readbyqxmd.com/read/27471845/interventions-for-treating-oral-leukoplakia-to-prevent-oral-cancer
#10
REVIEW
Giovanni Lodi, Roberto Franchini, Saman Warnakulasuriya, Elena Maria Varoni, Andrea Sardella, Alexander R Kerr, Antonio Carrassi, L C I MacDonald, Helen V Worthington
BACKGROUND: Oral leukoplakia is a relatively common oral lesion that, in a small proportion of people, precedes the development of oral cancer. Most leukoplakias are asymptomatic; therefore, the primary objective of treatment should be to prevent onset of cancer. This review updates our previous review, published in 2006. OBJECTIVES: To assess the effectiveness, safety and acceptability of treatments for leukoplakia in preventing oral cancer. SEARCH METHODS: We searched the following electronic databases: Cochrane Oral Health's Trials Register (to 16 May 2016), the Cochrane Central Register of Controlled Trials (CENTRAL) (the Cochrane Library, 2016, Issue 4), MEDLINE Ovid (1946 to 16 May 2016), Embase Ovid (1980 to 16 May 2016) and CancerLit via PubMed (1950 to 16 May 2016)...
2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27338543/review-of-information-technology-for-surgical-patient-care
#11
Jamie R Robinson, Hannah Huth, Gretchen P Jackson
BACKGROUND: Electronic health records (EHRs), computerized provider order entry (CPOE), and patient portals have experienced increased adoption by health care systems. The objective of this study was to review evidence regarding the impact of such health information technologies (HIT) on surgical practice. MATERIALS AND METHODS: A search of Medline, EMBASE, CINAHL, and the Cochrane Library was performed to identify data-driven, nonsurvey studies about the effects of HIT on surgical care...
June 1, 2016: Journal of Surgical Research
https://www.readbyqxmd.com/read/27330074/integrative-review-of-clinical-decision-support-for-registered-nurses-in-acute-care-settings
#12
Karen Dunn Lopez, Sheila M Gephart, Rebecca Raszewski, Vanessa Sousa, Lauren E Shehorn, Joanna Abraham
OBJECTIVE: To report on the state of the science of clinical decision support (CDS) for hospital bedside nurses. MATERIALS AND METHODS: We performed an integrative review of qualitative and quantitative peer-reviewed original research studies using a structured search of PubMed, Embase, Cumulative Index to Nursing and Applied Health Literature (CINAHL), Scopus, Web of Science, and IEEE Xplore (Institute of Electrical and Electronics Engineers Xplore Digital Library)...
June 21, 2016: Journal of the American Medical Informatics Association: JAMIA
https://www.readbyqxmd.com/read/27285450/interventions-for-treating-post-extraction-bleeding
#13
REVIEW
Kumbargere N Sumanth, Eachempati Prashanti, Himanshi Aggarwal, Pradeep Kumar, Ashok Lingappa, Murugan S Muthu, Salian Kiran Kumar Krishanappa
BACKGROUND: Post-extraction bleeding (PEB) is a recognised, frequently encountered complication in dental practice, which is defined as bleeding that continues beyond 8 to 12 hours after dental extraction. The incidence of post-extraction bleeding varies from 0% to 26%. If post-extraction bleeding is not managed, complications can range from soft tissue haematomas to severe blood loss. Local causes of bleeding include soft tissue and bone bleeding. Systemic causes include platelet problems, coagulation disorders or excessive fibrinolysis, and inherited or acquired problems (medication induced)...
2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27199197/electronic-health-records-then-now-and-in-the-future
#14
R S Evans
OBJECTIVES: Describe the state of Electronic Health Records (EHRs) in 1992 and their evolution by 2015 and where EHRs are expected to be in 25 years. Further to discuss the expectations for EHRs in 1992 and explore which of them were realized and what events accelerated or disrupted/derailed how EHRs evolved. METHODS: Literature search based on "Electronic Health Record", "Medical Record", and "Medical Chart" using Medline, Google, Wikipedia Medical, and Cochrane Libraries resulted in an initial review of 2,356 abstracts and other information in papers and books...
2016: Yearbook of Medical Informatics
https://www.readbyqxmd.com/read/27196988/systematic-review-of-adverse-effects-from-herbal-drugs-reported-in-randomized-controlled-trials
#15
REVIEW
Ji Young Lee, Seung Ah Jun, Sung Shin Hong, Yo Chan Ahn, Dong Soo Lee, Chang Gue Son
Herbal drugs have become a popular form of healthcare, raising concerns about their safety. This study aimed to characterize the adverse effects of herbal drugs through a systematic review of results reported in randomized controlled trials (RCTs). Using eight electronic databases including PubMed, the Cochrane library and six Korean medical databases, the frequency of reported toxicity was recorded based on drug composition and indication. Among 4957 potentially relevant articles, 242 papers comprised of 244 studies met our inclusion criteria; these included 111 studies of a single herb and 133 of multiple herbs...
September 2016: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/27150187/impact-of-e-alert-for-detection-of-acute-kidney-injury-on-processes-of-care-and-outcomes-protocol-for-a-systematic-review-and-meta-analysis
#16
Philippe Lachance, Pierre-Marc Villeneuve, Francis P Wilson, Nicholas M Selby, Robin Featherstone, Oleksa Rewa, Sean M Bagshaw
INTRODUCTION: Acute kidney injury (AKI) is a common complication in hospitalised patients. It imposes significant risk for major morbidity and mortality. Moreover, patients suffering an episode of AKI consume considerable health resources. Recently, a number of studies have evaluated the implementation of automated electronic alerts (e-alerts) configured from electronic medical records (EMR) and clinical information systems (CIS) to warn healthcare providers of early or impending AKI in hospitalised patients...
May 5, 2016: BMJ Open
https://www.readbyqxmd.com/read/27107443/electronic-medical-record-phenotyping-using-the-anchor-and-learn-framework
#17
Yoni Halpern, Steven Horng, Youngduck Choi, David Sontag
BACKGROUND: Electronic medical records (EMRs) hold a tremendous amount of information about patients that is relevant to determining the optimal approach to patient care. As medicine becomes increasingly precise, a patient's electronic medical record phenotype will play an important role in triggering clinical decision support systems that can deliver personalized recommendations in real time. Learning with anchors presents a method of efficiently learning statistically driven phenotypes with minimal manual intervention...
July 2016: Journal of the American Medical Informatics Association: JAMIA
https://www.readbyqxmd.com/read/27035020/progress-in-electronic-medical-record-adoption-in-canada
#18
(no author information available yet)
OBJECTIVE: To determine the rate of adoption of electronic medical records (EMRs) by physicians across Canada, provincial incentives, and perceived benefits of and barriers to EMR adoption. DATA SOURCES: Data on EMR adoption in Canada were collected from CINAHL, MEDLINE, PubMed, EMBASE, the Cochrane Library, the Health Council of Canada, Canada Health Infoway, government websites, regional EMR associations, and health professional association websites. STUDY SELECTION: After removal of duplicate articles, 236 documents were found matching the original search...
December 2015: Canadian Family Physician M├ędecin de Famille Canadien
https://www.readbyqxmd.com/read/26940992/a-hierarchical-method-to-automatically-encode-chinese-diagnoses-through-semantic-similarity-estimation
#19
Wenxin Ning, Ming Yu, Runtong Zhang
BACKGROUND: The accumulation of medical documents in China has rapidly increased in the past years. We focus on developing a method that automatically performs ICD-10 code assignment to Chinese diagnoses from the electronic medical records to support the medical coding process in Chinese hospitals. METHODS: We propose two encoding methods: one that directly determines the desired code (flat method), and one that hierarchically determines the most suitable code until the desired code is obtained (hierarchical method)...
2016: BMC Medical Informatics and Decision Making
https://www.readbyqxmd.com/read/26892337/use-of-scientific-social-networking-to-improve-the-research-strategies-of-pubmed-readers
#20
Pavel Evdokimov, Alexey Kudryavtsev, Ekaterina Ilgisonis, Elena Ponomarenko, Andrey Lisitsa
BACKGROUND: Keeping up with journal articles on a daily basis is an important activity of scientists engaged in biomedical research. Usually, journal articles and papers in the field of biomedicine are accessed through the Medline/PubMed electronic library. In the process of navigating PubMed, researchers unknowingly generate user-specific reading profiles that can be shared within a social networking environment. This paper examines the structure of the social networking environment generated by PubMed users...
2016: BMC Research Notes
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