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https://www.readbyqxmd.com/read/27830254/clinical-research-informatics-contributions-from-2015
#1
C Daniel, R Choquet
OBJECTIVES: To summarize key contributions to current research in the field of Clinical Research Informatics (CRI) and to select best papers published in 2015. METHOD: A bibliographic search using a combination of MeSH and free terms search over PubMed on Clinical Research Informatics (CRI) was performed followed by a double-blind review in order to select a list of candidate best papers to be then peer-reviewed by external reviewers. A consensus meeting between the two section editors and the editorial team was finally organized to conclude on the selection of best papers...
November 10, 2016: Yearbook of Medical Informatics
https://www.readbyqxmd.com/read/27794601/a-dynamically-reconfigurable-ambipolar-black-phosphorus-memory-device
#2
He Tian, Bingchen Deng, Matthew L Chin, Xiaodong Yan, Hao Jiang, Shu-Jen Han, Vivian Sun, Qiangfei Xia, Madan Dubey, Fengnian Xia, Han Wang
Nonvolatile charge-trap memory plays an important role in many modern electronics technologies, from portable electronic systems to large-scale data centers. Conventional charge-trap memory devices typically work with fixed channel carrier polarity and device characteristics. However, many emerging applications in reconfigurable electronics and neuromorphic computing require dynamically tunable properties in their electronic device components that can lead to enhanced circuit versatility and system functionalities...
November 1, 2016: ACS Nano
https://www.readbyqxmd.com/read/27754282/hw-04-3-global-network-for-her-based-big-data-analysis
#3
Peter Rijnbeek
Massive numbers of electronic health records are currently being collected globally, including structured data in the form of diagnoses, medications, laboratory test results, and unstructured data contained in clinical narratives. This opens unprecedented possibilities for research and ultimately patient care. However, actual use of these databases in a multi-center study is severely hampered by a variety of challenges, e.g., each database has a different database structure and uses different terminology systems...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27643279/hw-04-3-global-network-for-her-based-big-data-analysis
#4
Peter Rijnbeek
Massive numbers of electronic health records are currently being collected globally, including structured data in the form of diagnoses, medications, laboratory test results, and unstructured data contained in clinical narratives. This opens unprecedented possibilities for research and ultimately patient care. However, actual use of these databases in a multi-center study is severely hampered by a variety of challenges, e.g., each database has a different database structure and uses different terminology systems...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27577417/implementation-of-an-odm-and-hl7-compliant-electronic-patient-reported-outcome-system
#5
Iñaki Soto-Rey, Martin Dugas, Michael Storck
Interoperability is one of the biggest issues in health informatics despite of the huge effort invested to solve it. Clinical Data Interchange Standards Consortium (CDISC) and Health Level 7 (HL7) are two of the most recognized institutions working on this field. Several systems are becoming compliant with their standards; however, the process to accomplish it is not always straightforward. In this manuscript, we present the successful implementation of the CDISC ODM and HL7 import and export functions for "MoPat", a web-based multi-language electronic patient-reported outcomes system...
2016: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/27513627/psychometric-equivalence-of-electronic-and-telephone-completion-of-the-iciq-modules
#6
Alan D Uren, Nikki Cotterill, Sophie E Parke, Paul Abrams
AIMS: To assess the equivalence of touch-screen (hand-held iPad) and telephone completion of patient-completed International Consultation on Incontinence Questionnaire (ICIQ) modules by comparison with corresponding data collected using conventional paper-and-pencil methods. METHODS: Men and women, attending urology outpatients complaining of LUTS, were randomised to one of three groups which determined the order in which they completed three administrations of the same questionnaire: paper, iPad and telephone...
August 11, 2016: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/27499797/xafs-data-interchange-a-single-spectrum-xafs-data-file-format
#7
B Ravel, M Newville
We propose a standard data format for the interchange of XAFS data. The XAFS Data Interchange (XDI) standard is meant to encapsulate a single spectrum of XAFS along with relevant metadata. XDI is a text-based format with a simple syntax which clearly delineates metadata from the data table in a way that is easily interpreted both by a computer and by a human. The metadata header is inspired by the format of an electronic mail header, representing metadata names and values as an associative array. The data table is represented as columns of numbers...
2016: Journal of Physics. Conference Series
https://www.readbyqxmd.com/read/27494207/a-novel-epid-design-for-enhanced-contrast-and-detective-quantum-efficiency
#8
Joerg Rottmann, Daniel Morf, Rony Fueglistaller, George Zentai, Josh Star-Lack, Ross Berbeco
Beams-eye-view imaging applications such as real-time soft-tissue motion estimation are hindered by the inherently low image contrast of electronic portal imaging devices (EPID) currently available for clinical use. We introduce and characterize a novel EPID design that provides substantially increased detective quantum efficiency (DQE), contrast-to-noise ratio (CNR) and sensitivity without degradation in spatial resolution. The prototype design features a stack of four conventional EPID layers combined with low noise integrated readout electronics...
September 7, 2016: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/27467033/-online-counselling-the-prospect-of-a-therapeutic-connection
#9
O Giotakos, E Papadomarkaki
Over the last few years, Internet has become an integral part of daily life. An abundant source of information and a principal gateway of communication between individuals, Internet has been continuously gaining considerable ground as a tool of awareness and intervention in the area of public health. With regard to the field of mental health, Internet exhibits a credible potential in facilitating dialogue not only between experts and their beneficiaries but also between stakeholders. Moreover and with regard to various aspects of public concern, it can serve as a circulation portal of educational material between students and teachers...
April 2016: Psychiatrikē, Psychiatriki
https://www.readbyqxmd.com/read/27099841/high-level-of-agreement-between-electronic-and-paper-mode-of-administration-of-a-thyroid-specific-patient-reported-outcome-thypro
#10
Sofie Larsen Rasmussen, Lars Rejnmark, Eva Ebbehøj, Ulla Feldt-Rasmussen, Åse Krogh Rasmussen, Jakob Bue Bjorner, Torquil Watt
INTRODUCTION AND PURPOSE: Use of electronic questionnaires to collect health-related quality-of-life data has evolved as an alternative to paper questionnaires. For the electronic questionnaire to be used interchangeably with the validated paper questionnaire, measurement properties similar to the original must be demonstrated. The aim of the present study was to assess the equivalence between the paper version and the electronic version of the thyroid-related quality-of-life questionnaire ThyPRO...
March 2016: European Thyroid Journal
https://www.readbyqxmd.com/read/27023685/evaluation-of-a-therapeutic-interchange-from-fluticasone-salmeterol-to-mometasone-formoterol-in-patients-with-chronic-obstructive-pulmonary-disease
#11
Elaine Yip, Sahar Karimi, Linda T Pien
BACKGROUND: Combination treatment with an inhaled corticosteroid and long-acting beta2-agonist is among the many treatment options for chronic obstructive pulmonary disease (COPD) that has been shown to improve clinical outcomes. While mometasone/formoterol does not currently have an FDA-approved indication for COPD, evidence from 2 phase 3 trials demonstrated that mometasone/formoterol can improve lung function and was well tolerated in patients with moderate-to-very severe COPD. Based on these data, a therapeutic interchange was implemented in the Kaiser Permanente Mid-Atlantic States region to convert patients with a COPD diagnosis from fluticasone/salmeterol to mometasone/formoterol...
April 2016: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/26944737/current-applications-and-future-directions-for-the-cdisc-operational-data-model-standard-a-methodological-review
#12
REVIEW
Sam Hume, Jozef Aerts, Surendra Sarnikar, Vojtech Huser
INTRODUCTION: In order to further advance research and development on the Clinical Data Interchange Standards Consortium (CDISC) Operational Data Model (ODM) standard, the existing research must be well understood. This paper presents a methodological review of the ODM literature. Specifically, it develops a classification schema to categorize the ODM literature according to how the standard has been applied within the clinical research data lifecycle. This paper suggests areas for future research and development that address ODM's limitations and capitalize on its strengths to support new trends in clinical research informatics...
April 2016: Journal of Biomedical Informatics
https://www.readbyqxmd.com/read/26932349/systematic-review-of-cardiac-output-measurements-by-echocardiography-vs-thermodilution-the-techniques-are-not-interchangeable
#13
REVIEW
Mik Wetterslev, Hasse Møller-Sørensen, Rasmus Rothmann Johansen, Anders Perner
PURPOSE: Echocardiography is frequently used in the hemodynamic evaluation of critically ill patients, but inaccurate measurements may lead to wrong clinical decisions. The aim of our systematic review was to investigate the interchangeability of echocardiography with thermodilution technique in measuring cardiac output and its changes. METHODS: In August 2015 we systematically searched electronic databases and included studies investigating the echocardiographic measurement of cardiac output compared with thermodilution technique using the Bland-Altman method...
August 2016: Intensive Care Medicine
https://www.readbyqxmd.com/read/26911824/data-interchange-using-i2b2
#14
Jeffrey G Klann, Aaron Abend, Vijay A Raghavan, Kenneth D Mandl, Shawn N Murphy
OBJECTIVE: Reinventing data extraction from electronic health records (EHRs) to meet new analytical needs is slow and expensive. However, each new data research network that wishes to support its own analytics tends to develop its own data model. Joining these different networks without new data extraction, transform, and load (ETL) processes can reduce the time and expense needed to participate. The Informatics for Integrating Biology and the Bedside (i2b2) project supports data network interoperability through an ontology-driven approach...
September 2016: Journal of the American Medical Informatics Association: JAMIA
https://www.readbyqxmd.com/read/26873784/the-electron-microscopy-exchange-emx-initiative
#15
Roberto Marabini, Steven J Ludtke, Stephen C Murray, Wah Chiu, Jose M de la Rosa-Trevín, Ardan Patwardhan, J Bernard Heymann, Jose M Carazo
Three-dimensional electron microscopy (3DEM) of ice-embedded samples allows the structural analysis of large biological macromolecules close to their native state. Different techniques have been developed during the last forty years to process cryo-electron microscopy (cryo-EM) data. Not surprisingly, success in analysis and interpretation is highly correlated with the continuous development of image processing packages. The field has matured to the point where further progress in data and methods sharing depends on an agreement between the packages on how to describe common image processing tasks...
May 2016: Journal of Structural Biology
https://www.readbyqxmd.com/read/26818406/interchangeability-safety-and-efficacy-of-modified-release-drug-formulations-in-the-usa-the-case-of-opioid-and-other-nervous-system-drugs
#16
Enrique Seoane-Vazquez, Rosa Rodriguez-Monguio, Richard Hansen
BACKGROUND AND OBJECTIVES: Modified-release drugs may provide clinical advantages compared to immediate-release forms and improve convenience to the patient and health outcomes. Concerns have been raised regarding interchangeability, efficacy, and safety of modified-release formulations. This study analyses all US Food and Drug Administration (FDA)-approved modified-release formulations and market trends, and illustrates how bioequivalence and safety of generic modified-release products compare to their respective brand name drugs and other generic drugs with different formulation design characteristics...
April 2016: Clinical Drug Investigation
https://www.readbyqxmd.com/read/26770042/venous-thromboembolism-following-hip-and-knee-replacement-arthroplasty-in-korea-a-nationwide-study-based-on-claims-registry
#17
Sahnghoon Lee, Jee-In Hwang, Yunjung Kim, Pil Whan Yoon, Jeonghoon Ahn, Jeong Joon Yoo
The aim of this study was to examine the incidence and trends of clinically relevant venous thromboembolism (VTE) including deep vein thrombosis (DVT) and pulmonary embolism (PE) after hip and knee replacement arthroplasty (HKRA) in Korea. Between January 1 and December 31, 2010, 22,127 hip replacement arthroplasty (HRA) patients and 52,882 knee replacement arthroplasty (KRA) patients were enrolled in the analysis using the administrative claims database of the Health Insurance Review and Assessment Service (HIRA)...
January 2016: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/26714810/application-of-global-positioning-system-and-microsensor-technology-in-competitive-rugby-league-match-play-a-systematic-review-and-meta-analysis
#18
REVIEW
Joanne Hausler, Mark Halaki, Rhonda Orr
BACKGROUND: The use of global positioning system (GPS) devices with the inclusion of microsenor technology in rugby league enables measurement of player activity profiles to understand the demands of match-play and optimise on-field performance. OBJECTIVE: The aim of this review was to systematically review the use of GPS and microsensor technology to quantify player activity profiles in match-play, and conduct a meta-analysis of relevant movement variables in order to present the contemporary and emerging themes within rugby league...
April 2016: Sports Medicine
https://www.readbyqxmd.com/read/26691957/clinical-data-interchange-standards-consortium-standardization-of-biobank-data-a-feasibility-study
#19
Izumi Sato, Yohei Kawasaki, Kazuki Ide, Iori Sakakibara, Keiko Konomura, Hiroshi Yamada, Yasuhiro Tanaka
The National Center Biobank Network (NCBN), consisting of six national centers (NCs) for advanced and specialized medical care, was launched in Japan in 2012 to collect biological specimens and health-related data. The common data formats of the six NCs, however, are not widely known outside the NCs. Therefore, we investigated whether the data elements collected by the NCBN could be made to conform to the international standards of the Clinical Data Interchange Standards Consortium (CDISC). We attempted to map the NCBN data elements (202 items) onto the Study Data Tabulation Model (SDTM), a set of CDISC standards on the submission format of electronic clinical data approved by the Food and Drug Administration...
February 2016: Biopreservation and Biobanking
https://www.readbyqxmd.com/read/26635442/development-of-performance-dashboards-in-healthcare-sector-key-practical-issues
#20
Marjan Ghazisaeidi, Reza Safdari, Mashallah Torabi, Mahboobeh Mirzaee, Jebraeil Farzi, Azadeh Goodini
BACKGROUND: Static nature of performance reporting systems in health care sector has resulted in inconsistent, incomparable, time consuming, and static performance reports that are not able to transparently reflect a round picture of performance and effectively support healthcare managers' decision makings. So, the healthcare sector needs interactive performance management tools such as performance dashboards to measure, monitor, and manage performance more effectively. The aim of this article was to identify key issues that need to be addressed for developing high-quality performance dashboards in healthcare sector...
October 2015: Acta Informatica Medica: AIM
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