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https://www.readbyqxmd.com/read/28548547/facing-a-health-threat-in-a-complex-information-environment-a-national-representative-survey-examining-american-adults-behavioral-responses-to-the-2009-2010-a-h1n1-pandemic
#1
Leesa Lin, Rachel F McCloud, Minsoo Jung, Kasisomayajula Viswanath
BACKGROUND: Recent A(H1N1) studies suggest that intrapersonal and interpersonal factors may exert influence on people's preventive behaviors for avoiding the flu during pandemics. AIMS: Nonpharmaceutical interventions (NPIs) and vaccinations play key roles in containing disease transmission during a pandemic. We examined how intrapersonal and interpersonal factors influenced adoption of NPIs and vaccine uptake during the A(H1N1) pandemic of 2009. METHOD: The data come from a nationally representative sample survey of 1,569 American adults...
May 1, 2017: Health Education & Behavior: the Official Publication of the Society for Public Health Education
https://www.readbyqxmd.com/read/28547736/rice-bran-metabolome-contains-amino-acids-vitamins-cofactors-and-phytochemicals-with-medicinal-and-nutritional-properties
#2
Iman Zarei, Dustin G Brown, Nora Jean Nealon, Elizabeth P Ryan
BACKGROUND: Rice bran is a functional food that has shown protection against major chronic diseases (e.g. obesity, diabetes, cardiovascular disease and cancer) in animals and humans, and these health effects have been associated with the presence of bioactive phytochemicals. Food metabolomics uses multiple chromatography and mass spectrometry platforms to detect and identify a diverse range of small molecules with high sensitivity and precision, and has not been completed for rice bran...
December 2017: Rice
https://www.readbyqxmd.com/read/28547578/academic-health-center-psychology-representation-to-the-council-of-faculty-and-academic-societies-cfas-of-the-association-of-american-medical-colleges-aamc
#3
Barbara A Cubic, Laura A Shaffer
This paper outlines the perspectives of the two currently appointed representatives of the Association of Psychologists in Academic Health Centers (APAHC) to the Council of Faculty and Academic Societies (CFAS) of the Association of American Medical Colleges (AAMC). The authors focus on why it is important for psychologists, especially those in academic health centers (AHCs), to be part of CFAS. The goal of the paper is to demonstrate how involvement in organizations like the AAMC helps AHC psychologists serve as ambassadors for psychology in AHCs and assists AHC psychologists in staying fluent regarding hot topics within academic medicine...
May 25, 2017: Journal of Clinical Psychology in Medical Settings
https://www.readbyqxmd.com/read/28546311/evidence-for-functional-networks-within-the-human-brain-s-white-matter
#4
Michael Peer, Mor Nitzan, Atira S Bick, Netta Levin, Shahar Arzy
Investigation of the functional macro-scale organization of the human cortex is fundamental in modern neuroscience. While numerous studies have identified networks of interacting functional modules in the grey-matter, limited research was directed to the functional organization of the white-matter. Recent studies have demonstrated that the white-matter exhibits blood oxygen level dependent (BOLD) signal fluctuations similar to those of the grey-matter. Here we used these signal fluctuations to investigate whether the white-matter is organized as functional networks by applying a clustering analysis on resting-state functional MRI (RSfMRI) data from white-matter voxels, in 176 subjects (of both sexes)...
May 25, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28545844/rise-and-fall-of-the-two-visual-systems-theory
#5
Yves Rossetti, Laure Pisella, Robert D McIntosh
Among the many dissociations describing the visual system, the dual theory of two visual systems, respectively dedicated to perception and action, has yielded a lot of support. There are psychophysical, anatomical and neuropsychological arguments in favor of this theory. Several behavioral studies that used sensory and motor psychophysical parameters observed differences between perceptive and motor responses. The anatomical network of the visual system in the non-human primate was very readily organized according to two major pathways, dorsal and ventral...
May 22, 2017: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/28545246/increasing-the-use-of-urban-greenways-in-developing-countries-a-case-study-on-wutong-greenway-in-shenzhen-china
#6
Yiyong Chen, Weiying Gu, Tao Liu, Lei Yuan, Mali Zeng
Given the benefits of urban greenways on the health and well-being of urban populations, the increased use of urban greenways has garnered increasing attention. Studies on urban greenways, however, have been mostly conducted in Western countries, whereas there is limited knowledge on greenway use in urban areas in developing countries. To address this shortcoming, the present study selected Wutong Greenway in Shenzhen, China, as a case study and focused on the use pattern and factors that influence the frequency and duration of urban greenway use in developing countries...
May 23, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28544467/a-survey-on-the-beliefs-and-knowledge-of-gout-management-in-new-medical-graduates-new-south-wales-australia
#7
Matthew Terrill, John Riordan
AIM: To assess the beliefs and knowledge of gout management in new medical graduates. METHOD: A survey on gout management was sent to new medical graduates during their orientation week, New South Wales, Australia. RESULTS: Of 15 hospital networks, 11 agreed to participate. From these, 168 graduates responded (23.7% response rate). Most (81.1%) felt that gout was a serious disease, 51.2% answered that they had been taught adequately to manage acute gout, only 37...
May 25, 2017: International Journal of Rheumatic Diseases
https://www.readbyqxmd.com/read/28544056/exploring-the-knowledge-attitudes-and-needs-of-advance-care-planning-in-older-chinese-australians
#8
S S Yap, K Chen, K M Detering, S A Fraser
AIMS AND OBJECTIVES: The purpose of this study was to identify factors that influence the engagement of Chinese-Australians with advance care planning (ACP). BACKGROUND: Despite the benefits of ACP there is a low prevalence of ACP in the Chinese-Australian community. Reasons for this are often cited as cultural considerations and taboos surrounding future medical planning and death, however, other logistical factors may also be important. DESIGN: This qualitative study used a thematic analysis grounded theory approach to explore facilitators and barriers to engagement in ACP...
May 23, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28543973/advancing-the-adverse-outcome-pathway-framework-an-international-horizon-scanning-approach
#9
Carlie A LaLone, Gerald T Ankley, Scott E Belanger, Michelle R Embry, Geoff Hodges, Dries Knapen, Sharon Munn, Edward J Perkins, Murray A Rudd, Daniel L Villeneuve, Maurice Whelan, Catherine Willett, Xiaowei Zhang, Markus Hecker
Our ability to conduct whole-organism toxicity tests to understand chemical safety has been outpaced by the synthesis of new chemicals for a wide variety of commercial applications. As a result, scientists and risk assessors are turning to mechanistically based studies to increase efficiencies in chemical risk assessment and making greater use of in vitro and in silico methods to evaluate potential environmental and human health hazards. In this context, the adverse outcome pathway (AOP) framework has gained traction in regulatory science because it offers an efficient and effective means for capturing available knowledge describing the linkage between mechanistic data and the apical toxicity end points required for regulatory assessments...
June 2017: Environmental Toxicology and Chemistry
https://www.readbyqxmd.com/read/28542584/the-emergence-and-evolution-of-the-research-fronts-in-hiv-aids-research
#10
David Fajardo-Ortiz, Malaquias Lopez-Cervantes, Luis Duran, Michel Dumontier, Miguel Lara, Hector Ochoa, Victor M Castano
In this paper, we have identified and analyzed the emergence, structure and dynamics of the paradigmatic research fronts that established the fundamentals of the biomedical knowledge on HIV/AIDS. A search of papers with the identifiers "HIV/AIDS", "Human Immunodeficiency Virus", "HIV-1" and "Acquired Immunodeficiency Syndrome" in the Web of Science (Thomson Reuters), was carried out. A citation network of those papers was constructed. Then, a sub-network of the papers with the highest number of inter-citations (with a minimal in-degree of 28) was selected to perform a combination of network clustering and text mining to identify the paradigmatic research fronts and analyze their dynamics...
2017: PloS One
https://www.readbyqxmd.com/read/28542520/an-efficient-semi-supervised-community-detection-framework-in-social-networks
#11
Zhen Li, Yong Gong, Zhisong Pan, Guyu Hu
Community detection is an important tasks across a number of research fields including social science, biology, and physics. In the real world, topology information alone is often inadequate to accurately find out community structure due to its sparsity and noise. The potential useful prior information such as pairwise constraints which contain must-link and cannot-link constraints can be obtained from domain knowledge in many applications. Thus, combining network topology with prior information to improve the community detection accuracy is promising...
2017: PloS One
https://www.readbyqxmd.com/read/28542505/alzhcpi-a-knowledge-base-for-predicting-chemical-protein-interactions-towards-alzheimer-s-disease
#12
Jiansong Fang, Ling Wang, Yecheng Li, Wenwen Lian, Xiaocong Pang, Hong Wang, Dongsheng Yuan, Qi Wang, Ai-Lin Liu, Guan-Hua Du
Alzheimer's disease (AD) is a complicated progressive neurodegeneration disorder. To confront AD, scientists are searching for multi-target-directed ligands (MTDLs) to delay disease progression. The in silico prediction of chemical-protein interactions (CPI) can accelerate target identification and drug discovery. Previously, we developed 100 binary classifiers to predict the CPI for 25 key targets against AD using the multi-target quantitative structure-activity relationship (mt-QSAR) method. In this investigation, we aimed to apply the mt-QSAR method to enlarge the model library to predict CPI towards AD...
2017: PloS One
https://www.readbyqxmd.com/read/28542200/predicting-cryptic-links-in-host-parasite-networks
#13
Tad Dallas, Andrew W Park, John M Drake
Networks are a way to represent interactions among one (e.g., social networks) or more (e.g., plant-pollinator networks) classes of nodes. The ability to predict likely, but unobserved, interactions has generated a great deal of interest, and is sometimes referred to as the link prediction problem. However, most studies of link prediction have focused on social networks, and have assumed a completely censused network. In biological networks, it is unlikely that all interactions are censused, and ignoring incomplete detection of interactions may lead to biased or incorrect conclusions...
May 25, 2017: PLoS Computational Biology
https://www.readbyqxmd.com/read/28541580/genes-and-gene-clusters-related-to-genotype-and-drought-induced-variation-in-saccharification-potential-lignin-content-and-wood-anatomical-traits-in-populus-nigra%C3%A2
#14
Henning Wildhagen, Shanty Paul, Mike Allwright, Hazel K Smith, Marta Malinowska, Sabine K Schnabel, M João Paulo, Federica Cattonaro, Vera Vendramin, Simone Scalabrin, Dennis Janz, Cyril Douthe, Oliver Brendel, Cyril Buré, David Cohen, Irène Hummel, Didier Le Thiec, Fred van Eeuwijk, Joost J B Keurentjes, Jaume Flexas, Michele Morgante, Paul Robson, Marie-Béatrice Bogeat-Triboulot, Gail Taylor, Andrea Polle
Wood is a renewable resource that can be employed for the production of second generation biofuels by enzymatic saccharification and subsequent fermentation. Knowledge on how the saccharification potential is affected by genotype-related variation of wood traits and drought is scarce. Here, we used three Populus nigra L. genotypes from habitats differing in water availability to (i) investigate the relationships between wood anatomy, lignin content and saccharification and (ii) identify genes and co-expressed gene clusters related to genotype and drought-induced variation in wood traits and saccharification potential...
May 24, 2017: Tree Physiology
https://www.readbyqxmd.com/read/28541219/inferring-social-influence-of-anti-tobacco-mass-media-campaign
#15
Qianyi Zhan, Jiawei Zhang, Philip Yu, Sherry Emery, Junyuan Xie
Anti-tobacco mass media campaigns are designed to influence tobacco users. It has been proved that campaigns will produce users' changes in awareness, knowledge, and attitudes, and also produce meaningful behavior change of audience. Antismoking television advertising is the most important part in the campaign. Meanwhile nowadays successful online social networks are creating new media environment, however little is known about the relation between social conversations and anti-tobacco campaigns. This paper aims to infer social influence of these campaigns, and the problem is formally referred to as the Social Influence inference of anti-Tobacco mass mEdia campaigns (SITE) problem...
May 23, 2017: IEEE Transactions on Nanobioscience
https://www.readbyqxmd.com/read/28540763/hiv-infection-risk-factors-and-health-services-use-among-male-to-female-transgender-sex-workers-a-cross-sectional-study-in-portugal
#16
Ana Gama, Maria Rosário Oliveira Martins, Luís Mendão, Henrique Barros, Sónia Dias
Male-to-female transgender sex workers (TSW) have been identified as a key population at risk for HIV. This study examined risk behaviors and HIV prevalence among TSW, and described health services use. A participatory cross-sectional survey was conducted with 125 TSW recruited in locations and networks where sex workers congregate. HIV-risk behaviors were common among participants. Inconsistent condom use with clients in the previous month was reported by 12.0% of participants and was associated with Portuguese nationality, inconsistent condom use with non-paying partners and not been reached by HIV prevention programs in the previous year...
May 25, 2017: AIDS Care
https://www.readbyqxmd.com/read/28539591/characterization-of-the-adult-head-transcriptome-and-identification-of-migration-and-olfaction-genes-in-the-oriental-armyworm-mythimna-separate
#17
Hai-Xu Bian, Hong-Fang Ma, Xi-Xi Zheng, Ming-Hui Peng, Yu-Ping Li, Jun-Fang Su, Huan Wang, Qun Li, Run-Xi Xia, Yan-Qun Liu, Xing-Fu Jiang
The oriental armyworm Mythimna separate is an economically important insect with a wide distribution and strong migratory activity. However, knowledge about the molecular mechanisms regulating the physiological and behavioural responses of the oriental armyworm is scarce. In the present study, we took a transcriptomic approach to characterize the gene network in the adult head of M. separate. The sequencing and de novo assembly yielded 63,499 transcripts, which were further assembled into 46,459 unigenes with an N50 of 1,153 bp...
May 24, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28539263/nutrients-neurogenesis-and-brain-ageing-from-disease-mechanisms-to-therapeutic-opportunities
#18
REVIEW
Marco Fidaleo, Virve Cavallucci, Giovambattista Pani
Appreciation of the physiological relevance of mammalian adult neurogenesis has in recent years rapidly expanded from a phenomenon of homeostatic cell replacement and brain repair to the current view of a complex process involved in high order cognitive functions. In parallel, an array of endogenous or exogenous triggers of neurogenesis have also been identified, among which metabolic and nutritional cues have drawn significant attention. Converging evidence from animal and in vitro studies point to nutrient sensing and energy metabolism as major physiological determinants of neural stem cell fate, and modulators of the whole neurogenic process...
May 21, 2017: Biochemical Pharmacology
https://www.readbyqxmd.com/read/28538919/expert-communities-and-interest-formation-in-the-brazilian-aids-program
#19
Regina Ferro do Lago, Nilson do Rosário Costa
This paper examines the role of the Technical Advisory Committee for antiretroviral therapy of the Brazilian AIDS program in mediating the decision-making process of including new antiretroviral (ARV) drugs in the Unified Health System services by the end of the 2000s. We conducted documental analysis and interviews with key informants from the governmental sphere and professionals. The work features the Technical Advisory Committee as an "expert community", defined as a network of individuals with expertise and competence in a particular sphere and whose knowledge is relevant in critical public policy decision areas...
May 2017: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/28538415/network-meta-analysis-of-chinese-herbal-injections-combined-with-the-chemotherapy-for-the-treatment-of-pancreatic-cancer
#20
Dan Zhang, Jiarui Wu, Shi Liu, Xiaomeng Zhang, Bing Zhang
BACKGROUND: This study sought to use a network meta-analysis to assess the effectiveness and safety of Chinese herbal injections (CHIs) combined with the chemotherapy for the treatment of pancreatic cancer. METHODS: Randomized controlled trials (RCTs) regarding CHIs to treat pancreatic cancer were searched in PubMed, the Cochrane library, Embase, the China National Knowledge Infrastructure Database (CNKI), the Wan-Fang Database, the Chinese Scientific Journals Full-text Database (VIP), and the Chinese Biomedical Literature Database (SinoMed) up to November 2016...
May 2017: Medicine (Baltimore)
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